product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
MAT2A Antibody - BSA Free
catalog :
NB110-94158
quantity :
0.1 ml (also 0.025 ml)
price :
399 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat, bovine
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
more info or order :
citations: 27
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:1000; fig 3
  • western blot; mouse; 1:1000; fig 3
Scotton C, Bovolenta M, Schwartz E, Falzarano M, Martoni E, Passarelli C, et al. Deep RNA profiling identified CLOCK and molecular clock genes as pathophysiological signatures in collagen VI myopathy. J Cell Sci. 2016;129:1671-84 pubmed publisher
Hoang L, Aoyama E, Hiasa M, Omote H, Kubota S, Kuboki T, et al. Positive Regulation of S-Adenosylmethionine on Chondrocytic Differentiation via Stimulation of Polyamine Production and the Gene Expression of Chondrogenic Differentiation Factors. Int J Mol Sci. 2023;24: pubmed publisher
Acosta C, Clemons G, Citadin C, Carr W, Udo M, Tesic V, et al. A role for protein arginine methyltransferase 7 in repetitive and mild traumatic brain injury. Neurochem Int. 2023;166:105524 pubmed publisher
Yamamoto J, Inubushi S, Han Q, Tashiro Y, Sugisawa N, Hamada K, et al. Linkage of methionine addiction, histone lysine hypermethylation, and malignancy. iScience. 2022;25:104162 pubmed publisher
Ampomah P, Cai B, Sukka S, Gerlach B, Yurdagul A, Wang X, et al. Macrophages use apoptotic cell-derived methionine and DNMT3A during efferocytosis to promote tissue resolution. Nat Metab. 2022;4:444-457 pubmed publisher
LeBlanc L, Kim M, Kambhampati A, Son A, Ramirez N, Kim J. β-catenin links cell seeding density to global gene expression during mouse embryonic stem cell differentiation. iScience. 2022;25:103541 pubmed publisher
Scarborough A, Flaherty J, Hunter O, Liu K, Kumar A, Xing C, et al. SAM homeostasis is regulated by CFIm-mediated splicing of MAT2A. elife. 2021;10: pubmed publisher
Secker K, Bloechl B, Keppeler H, Duerr Stoerzer S, Schmid H, Schneidawind D, et al. MAT2A as Key Regulator and Therapeutic Target in MLLr Leukemogenesis. Cancers (Basel). 2020;12: pubmed publisher
Zhang M, Liu L, Cao X, Liu Y, Di J, Huang X, et al. Efficiently accumulating germ-like stem cells from mouse postnatal ovary by in situ tissue culture. Dev Growth Differ. 2020;62:223-231 pubmed publisher
Zhang R, Ma J, Avery J, Sambandam V, Nguyen T, Xu B, et al. GLI1 Inhibitor SRI-38832 Attenuates Chemotherapeutic Resistance by Downregulating NBS1 Transcription in BRAFV600E Colorectal Cancer. Front Oncol. 2020;10:241 pubmed publisher
Wheeler M, Clark I, Tjon E, Li Z, Zandee S, Couturier C, et al. MAFG-driven astrocytes promote CNS inflammation. Nature. 2020;578:593-599 pubmed publisher
Roy D, Chen J, Mamane V, Ma E, Muhire B, Sheldon R, et al. Methionine Metabolism Shapes T Helper Cell Responses through Regulation of Epigenetic Reprogramming. Cell Metab. 2020;31:250-266.e9 pubmed publisher
Lei W, Han F, Hu M, Liang Q, Meng T, Zhou Q, et al. Protein phosphatase 6 is a key factor regulating spermatogenesis. Cell Death Differ. 2019;: pubmed publisher
Tu Z, Mu X, Chen X, Geng Y, Zhang Y, Li Q, et al. Dibutyl phthalate exposure disrupts the progression of meiotic prophase I by interfering with homologous recombination in fetal mouse oocytes. Environ Pollut. 2019;252:388-398 pubmed publisher
Bhattacharyya T, Walker M, Powers N, Brunton C, Fine A, Petkov P, et al. Prdm9 and Meiotic Cohesin Proteins Cooperatively Promote DNA Double-Strand Break Formation in Mammalian Spermatocytes. Curr Biol. 2019;29:1002-1018.e7 pubmed publisher
Morgan M, Kabayama Y, Much C, Ivanova I, Di Giacomo M, Auchynnikava T, et al. A programmed wave of uridylation-primed mRNA degradation is essential for meiotic progression and mammalian spermatogenesis. Cell Res. 2019;29:221-232 pubmed publisher
Tian H, Billings T, Petkov P. CXXC1 is not essential for normal DNA double-strand break formation and meiotic recombination in mouse. PLoS Genet. 2018;14:e1007657 pubmed publisher
Stone O, El Brolosy M, Wilhelm K, Liu X, Romão A, Grillo E, et al. Loss of pyruvate kinase M2 limits growth and triggers innate immune signaling in endothelial cells. Nat Commun. 2018;9:4077 pubmed publisher
Adams S, Maezawa S, Alavattam K, Abe H, Sakashita A, Shroder M, et al. RNF8 and SCML2 cooperate to regulate ubiquitination and H3K27 acetylation for escape gene activation on the sex chromosomes. PLoS Genet. 2018;14:e1007233 pubmed publisher
Testa E, Nardozi D, Antinozzi C, Faieta M, Di Cecca S, Caggiano C, et al. H2AFX and MDC1 promote maintenance of genomic integrity in male germ cells. J Cell Sci. 2018;131: pubmed publisher
Zhong Q, Liu Z, Lin Z, Hu Z, Yuan L, Liu Y, et al. The RARS-MAD1L1 Fusion Gene Induces Cancer Stem Cell-like Properties and Therapeutic Resistance in Nasopharyngeal Carcinoma. Clin Cancer Res. 2018;24:659-673 pubmed publisher
Tomasi M, Cossu C, Spissu Y, Floris A, Ryoo M, Iglesias Ara A, et al. S-adenosylmethionine and methylthioadenosine inhibit cancer metastasis by targeting microRNA 34a/b-methionine adenosyltransferase 2A/2B axis. Oncotarget. 2017;8:78851-78869 pubmed publisher
Wojtas M, Pandey R, Mendel M, Homolka D, Sachidanandam R, Pillai R. Regulation of m6A Transcripts by the 3'?5' RNA Helicase YTHDC2 Is Essential for a Successful Meiotic Program in the Mammalian Germline. Mol Cell. 2017;68:374-387.e12 pubmed publisher
Dai J, Voloshin O, Potapova S, Camerini Otero R. Meiotic Knockdown and Complementation Reveals Essential Role of RAD51 in Mouse Spermatogenesis. Cell Rep. 2017;18:1383-1394 pubmed publisher
Parvanov E, Tian H, Billings T, Saxl R, Spruce C, Aithal R, et al. PRDM9 interactions with other proteins provide a link between recombination hotspots and the chromosomal axis in meiosis. Mol Biol Cell. 2017;28:488-499 pubmed publisher
Ikegami K, Atsumi Y, Yorinaga E, Ono H, Murayama I, Nakane Y, et al. Low temperature-induced circulating triiodothyronine accelerates seasonal testicular regression. Endocrinology. 2015;156:647-59 pubmed publisher
Ramani K, Donoyan S, Tomasi M, Park S. Role of methionine adenosyltransferase α2 and β phosphorylation and stabilization in human hepatic stellate cell trans-differentiation. J Cell Physiol. 2015;230:1075-85 pubmed publisher
product information
master code :
NB110-94158
SKU :
NB110-94158
product name :
MAT2A Antibody - BSA Free
unit size :
0.1 ml (also 0.025 ml)
description :
The MAT2A Antibody - BSA Free from Novus is a rabbit polyclonal antibody to MAT2A. This antibody reacts with bovine,human,mouse,porcine,primate,rat. The MAT2A Antibody - BSA Free has been validated for the following applications: Immunoprecipitation,Western Blot,Immunohistochemistry,Immunohistochemistry-Paraffin,Simple Western,Immunocytochemistry/ Immunofluorescence.
target :
MAT2A
category :
Primary Antibodies
buffer :
PBS
clonality :
Polyclonal
concentration :
1.0 mg/ml
conjugate :
Unconjugated
host :
Rabbit
immunogen :
Synthetic peptide made to an N-terminal portion of human MAT2A (within residues 1-100). [Swiss-Prot# P31153]
isotype :
IgG
purity :
Immunogen affinity purified
species :
Bovine,Human,Mouse,Porcine,Primate,Rat
theoretical molecular weight :
43 kDa
gene symbol :
MAT2A
applications :
Immunoprecipitation,Western Blot,Immunohistochemistry,Immunohistochemistry-Paraffin,Simple Western,Immunocytochemistry/ Immunofluorescence
USD :
399 USD
alt names :
AdoMet synthase 2, AMS2, EC 2.5.1.6, MAT 2, MATA2SAMS2adoMet synthetase 2, MATII, MAT-II, Methionine adenosyltransferase 2, Methionine adenosyltransferase II, methionine adenosyltransferase II, alpha, S-adenosylmethionine synthase isoform type-2, S-adenosylmethionine synthetase isoform type-2
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.