product summary
Loading...
company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
Ki67/MKI67 Antibody - BSA Free
catalog :
NB110-89717
quantity :
0.1 ml (also 0.025 ml)
price :
469 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
Alexa Fluor 594
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 73
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - frozen section; mouse; 1:200; loading ...; fig 6j
Naito H, Iba T, Wakabayashi T, Tai Nagara I, Suehiro J, Jia W, et al. TAK1 Prevents Endothelial Apoptosis and Maintains Vascular Integrity. Dev Cell. 2019;48:151-166.e7 pubmed publisher
  • immunocytochemistry; mouse; 1:100; fig 5a
  • immunocytochemistry; human; 1:100; loading ...; fig s12a
Albrengues J, Shields M, Ng D, Park C, Ambrico A, Poindexter M, et al. Neutrophil extracellular traps produced during inflammation awaken dormant cancer cells in mice. Science. 2018;361: pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:200; fig 3
Kai T, Tsukamoto Y, Hijiya N, Tokunaga A, Nakada C, Uchida T, et al. Kidney-specific knockout of Sav1 in the mouse promotes hyperproliferation of renal tubular epithelium through suppression of the Hippo pathway. J Pathol. 2016;239:97-108 pubmed publisher
  • immunohistochemistry - paraffin section; mouse
Aggarwal A, Höbaus J, Tennakoon S, Prinz Wohlgenannt M, Graça J, Price S, et al. Active vitamin D potentiates the anti-neoplastic effects of calcium in the colon: A cross talk through the calcium-sensing receptor. J Steroid Biochem Mol Biol. 2016;155:231-8 pubmed publisher
Moon D, Padanilam B, Park K, Kim J. Loss of SAV1 in Kidney Proximal Tubule Induces Maladaptive Repair after Ischemia and Reperfusion Injury. Int J Mol Sci. 2024;25: pubmed publisher
Metti S, Da Ros F, Toniato G, Cescon M, Bonaldo P. Native collagen VI delays early muscle stem cell differentiation. J Cell Sci. 2024;137: pubmed publisher
Pastor Alonso O, Syeda Zahra A, Kaske B, Garc xed a Moreno F, Tetzlaff F, Bockelmann E, et al. Generation of adult hippocampal neural stem cells occurs in the early postnatal dentate gyrus and depends on cyclin D2. EMBO J. 2024;43:317-338 pubmed publisher
Chen F, Li H, Chung D, Mak A, Leung F, Chan H, et al. IL-4/STAT6 axis observed to reverse proliferative defect in SCA3 patient-derived neural progenitor cells. Clin Exp Pharmacol Physiol. 2024;51:30-39 pubmed publisher
Zhang A, Lau N, Wong A, Brown L, Coleman I, De Sarkar N, et al. Concurrent Targeting of HDAC and PI3K to Overcome Phenotypic Heterogeneity of Castration-resistant and Neuroendocrine Prostate Cancers. Cancer Res Commun. 2023;3:2358-2374 pubmed publisher
Kirkeby A, Nelander J, Hoban D, Rogelius N, Bjartmarz H, Storm P, et al. Preclinical quality, safety, and efficacy of a human embryonic stem cell-derived product for the treatment of Parkinson's disease, STEM-PD. Cell Stem Cell. 2023;30:1299-1314.e9 pubmed publisher
Dominicis A, Del Giovane A, Torreggiani M, Recchia A, Ciccarone F, Ciriolo M, et al. N-Acetylaspartate Drives Oligodendroglial Differentiation via Histone Deacetylase Activation. Cells. 2023;12: pubmed publisher
Burke Kleinman J, Rubianto J, Hou G, Santerre J, Bendeck M. Matrix-Binding, N-Cadherin-Targeting Chimeric Peptide Inhibits Intimal Thickening but Not Endothelial Repair in Balloon-Injured Carotid Arteries. Arterioscler Thromb Vasc Biol. 2023;43:1639-1652 pubmed publisher
Inoue M, Tanida T, Kondo T, Takenaka S, Nakajima T. Oxygen-glucose deprivation-induced glial cell reactivity in the rat primary neuron-glia co-culture. J Vet Med Sci. 2023;85:799-808 pubmed publisher
Halder S, Delorme Walker V, Milner R. β1 integrin is essential for blood-brain barrier integrity under stable and vascular remodelling conditions; effects differ with age. Fluids Barriers CNS. 2023;20:52 pubmed publisher
Grujic M, Nguyen T, H xe9 chard T, Wang H, Lampinen M, Paivandy A, et al. Phenotypic Switch and Growth of Melanoma Spheroids in the Presence of Mast Cells: Potential Impact of Nutrient-starvation Effects. Anticancer Res. 2023;43:1415-1426 pubmed publisher
Tang Y, Ponandai Srinivasan S, Frisendahl C, Andersson J, Pavone D, Stewart E, et al. Bromocriptine inhibits proliferation in the endometrium from women with adenomyosis. Front Endocrinol (Lausanne). 2023;14:1026168 pubmed publisher
Colella M, Cuomo D, Nittoli V, Amoresano A, Porciello A, Reale C, et al. A Cross-Species Analysis Reveals Dysthyroidism of the Ovaries as a Common Trait of Premature Ovarian Aging. Int J Mol Sci. 2023;24: pubmed publisher
Jara Z, Harford T, Singh K, Desnoyer R, Kumar A, Srinivasan D, et al. Distinct Mechanisms of β-Arrestin-Biased Agonist and Blocker of AT1R in Preventing Aortic Aneurysm and Associated Mortality. Hypertension. 2023;80:385-402 pubmed publisher
Li T, Akinade T, Zhou J, Wang H, Tong Q, He S, et al. Therapeutic Nanocarriers Inhibit Chemotherapy-Induced Breast Cancer Metastasis. Adv Sci (Weinh). 2022;9:e2203949 pubmed publisher
Yamamoto Fukuda T, Akiyama N, Tatsumi N, Okabe M, Kojima H. Keratinocyte Growth Factor Stimulates Growth of p75+ Neural Crest Lineage Cells During Middle Ear Cholesteatoma Formation in Mice. Am J Pathol. 2022;: pubmed publisher
Du J, Sarkar R, Li Y, He L, Kang W, Liao W, et al. N6-adenomethylation of GsdmC is essential for Lgr5+ stem cell survival to maintain normal colonic epithelial morphogenesis. Dev Cell. 2022;57:1976-1994.e8 pubmed publisher
Akiyama N, Yamamoto Fukuda T, Yoshikawa M, Kojima H. Analysis of the epidermal growth factor receptor/phosphoinositide-dependent protein kinase-1 axis in tumor of the external auditory canal in response to epidermal growth factor stimulation. Laryngoscope Investig Otolaryngol. 2022;7:730-739 pubmed publisher
Roby K, Lieberman A, Kim B, Rodr xed guez N, Posimo J, Tsang T, et al. Loss of p19Arf promotes fibroblast survival during leucine deprivation. Biol Open. 2022;11: pubmed publisher
Caire R, Audoux E, Courbon G, Michaud E, Petit C, Dalix E, et al. YAP/TAZ: Key Players for Rheumatoid Arthritis Severity by Driving Fibroblast Like Synoviocytes Phenotype and Fibro-Inflammatory Response. Front Immunol. 2021;12:791907 pubmed publisher
Sun D, Tian Y, Lin C, Hung S, Uen Y, Hseu Y, et al. A novel mechanism driving poor-prognostic gastric cancer: overexpression of the transcription factor Krüppel-like factor 16 promotes growth and metastasis of gastric cancer through regulating the Notch pathway. Am J Cancer Res. 2021;11:2717-2735 pubmed
Moroki T, Matsuo S, Hatakeyama H, Hayashi S, Matsumoto I, Suzuki S, et al. Databases for technical aspects of immunohistochemistry: 2021 update. J Toxicol Pathol. 2021;34:161-180 pubmed publisher
Sarvestani S, SIGNS S, Hu B, Yeu Y, Feng H, Ni Y, et al. Induced organoids derived from patients with ulcerative colitis recapitulate colitic reactivity. Nat Commun. 2021;12:262 pubmed publisher
Roostalu U, Lercke Skytte J, Gravesen Salinas C, Klein T, Vrang N, Jelsing J, et al. 3D quantification of changes in pancreatic islets in mouse models of diabetes type I and II. Dis Model Mech. 2020;13: pubmed publisher
Jin L, Cai Q, Wang S, Wang S, Wang J, Quan Z. Long noncoding RNA PVT1 promoted gallbladder cancer proliferation by epigenetically suppressing miR-18b-5p via DNA methylation. Cell Death Dis. 2020;11:871 pubmed publisher
Decker J, Kandagatla P, Wan L, Bernstein R, Ma J, Shea L, et al. Cyclin E overexpression confers resistance to trastuzumab through noncanonical phosphorylation of SMAD3 in HER2+ breast cancer. Cancer Biol Ther. 2020;21:994-1004 pubmed publisher
Testa S, Riera C, Fornetti E, Riccio F, Fuoco C, Bernardini S, et al. Skeletal Muscle-Derived Human Mesenchymal Stem Cells: Influence of Different Culture Conditions on Proliferative and Myogenic Capabilities. Front Physiol. 2020;11:553198 pubmed publisher
Mouillet J, Goff J, Sadovsky E, Sun H, Parks T, Chu T, et al. Transgenic expression of human C19MC miRNAs impacts placental morphogenesis. Placenta. 2020;101:208-214 pubmed publisher
Fein M, He X, Almeida A, Bru x17e as E, Pommier A, Yan R, et al. Cancer cell CCR2 orchestrates suppression of the adaptive immune response. J Exp Med. 2020;217: pubmed publisher
Nakane Y, Kemmochi Y, Ogawa N, Sasase T, Ohta T, Higami Y, et al. Hyperglycemia contributes to the development of Leydig cell hyperplasia in male Spontaneously Diabetic Torii rats. J Toxicol Pathol. 2020;33:121-129 pubmed publisher
Yamamoto Fukuda T, Akiyama N, Kojima H. L1CAM-ILK-YAP Mechanotransduction Drives Proliferative Activity of Epithelial Cells in Middle Ear Cholesteatoma. Am J Pathol. 2020;: pubmed publisher
Meng C, Tian G, Xu C, Li X, Zhang Y, Wang Y, et al. Hippo kinases MST1 and MST2 control the differentiation of the epididymal initial segment via the MEK-ERK pathway. Cell Death Differ. 2020;: pubmed publisher
Xu C, Wang L, Zhang Y, Li W, Li J, Wang Y, et al. Tubule-Specific Mst1/2 Deficiency Induces CKD via YAP and Non-YAP Mechanisms. J Am Soc Nephrol. 2020;31:946-961 pubmed publisher
Lemons K, Fu Z, Ogura T, Lin W. TRPM5-expressing Microvillous Cells Regulate Region-specific Cell Proliferation and Apoptosis During Chemical Exposure. Neuroscience. 2020;434:171-190 pubmed publisher
Tsai M, Huang C, Wei Y, Liu T, Lin M, Yi L, et al. Combined Chibby and β-Catenin Predicts Clinical Outcomes in Patients with Hepatocellular Carcinoma. Int J Mol Sci. 2020;21: pubmed publisher
Chou P, Lin Y, Wu S, Lin S, Srinivasan P, Hsieh D, et al. Supercritical Carbon Dioxide-decellularized Porcine Acellular Dermal Matrix combined with Autologous Adipose-derived Stem Cells: Its Role in Accelerated Diabetic Wound Healing. Int J Med Sci. 2020;17:354-367 pubmed publisher
Kim Y, Tsang T, Anderson G, Posimo J, Brady D. Inhibition of BCL2 Family Members Increases the Efficacy of Copper Chelation in BRAFV600E-Driven Melanoma. Cancer Res. 2020;80:1387-1400 pubmed publisher
Li Q, Liu B, Chao H, Ji Y, Lu Y, Mehmood R, et al. LRIG1 is a pleiotropic androgen receptor-regulated feedback tumor suppressor in prostate cancer. Nat Commun. 2019;10:5494 pubmed publisher
Li H, Yu Y, Zhao Y, Wu D, Yu X, Lu J, et al. Small molecule inhibitor agerafenib effectively suppresses neuroblastoma tumor growth in mouse models via inhibiting ERK MAPK signaling. Cancer Lett. 2019;: pubmed publisher
Gunin A, Golubtsova N, Kravtsova O, Subbotkin A, Subbotkina N, Filippov F. Number, Proliferative Activity, and Expression of Thyroid Hormone Receptors in Dermal Fibroblasts in Mice with Changed Thyroid Status. Bull Exp Biol Med. 2019;166:797-801 pubmed publisher
Li S, Song Y, Quach C, Guo H, Jang G, Maazi H, et al. Transcriptional regulation of autophagy-lysosomal function in BRAF-driven melanoma progression and chemoresistance. Nat Commun. 2019;10:1693 pubmed publisher
Amano H, Chaudhury A, Rodriguez Aguayo C, Lu L, Akhanov V, Catic A, et al. Telomere Dysfunction Induces Sirtuin Repression that Drives Telomere-Dependent Disease. Cell Metab. 2019;29:1274-1290.e9 pubmed publisher
Xu J, Song J, Yang X, Guo J, Wang T, Zhuo W. ProNGF siRNA inhibits cell proliferation and invasion of pancreatic cancer cells and promotes anoikis. Biomed Pharmacother. 2019;111:1066-1073 pubmed publisher
Gunin A, Golubtsova N, Subbotkina N, Subbotkin A. [The influence of metformin on age-related changes in the number and proliferation of dermal fibroblasts in mice.]. Adv Gerontol. 2018;31:505-509 pubmed
Stojiljkovic M, Ain Q, Bondeva T, Heller R, Schmeer C, Witte O. Phenotypic and functional differences between senescent and aged murine microglia. Neurobiol Aging. 2019;74:56-69 pubmed publisher
Kumari A, Yokota Y, Li L, Bradley R, Mistretta C. Species generalization and differences in Hedgehog pathway regulation of fungiform and circumvallate papilla taste function and somatosensation demonstrated with sonidegib. Sci Rep. 2018;8:16150 pubmed publisher
Gopalakrishnan K, Teitelbaum S, Wetmur J, Manservisi F, Falcioni L, Panzacchi S, et al. Histology and Transcriptome Profiles of the Mammary Gland across Critical Windows of Development in Sprague Dawley Rats. J Mammary Gland Biol Neoplasia. 2018;23:149-163 pubmed publisher
Anurag M, Punturi N, Hoog J, Bainbridge M, Ellis M, Haricharan S. Comprehensive Profiling of DNA Repair Defects in Breast Cancer Identifies a Novel Class of Endocrine Therapy Resistance Drivers. Clin Cancer Res. 2018;24:4887-4899 pubmed publisher
Duteil D, Tourrette Y, Eberlin A, Willmann D, Patel D, Friedrichs N, et al. The histone acetyltransferase inhibitor Nir regulates epidermis development. Development. 2018;145: pubmed publisher
Tachikawa S, Shimizu M, Maruyama K, Ohnuma K. Thalidomide induces apoptosis during early mesodermal differentiation of human induced pluripotent stem cells. In Vitro Cell Dev Biol Anim. 2018;54:231-240 pubmed publisher
Kumari P, Saha I, Narayanan A, Narayanan S, Takaoka A, Kumar N, et al. Essential role of HCMV deubiquitinase in promoting oncogenesis by targeting anti-viral innate immune signaling pathways. Cell Death Dis. 2017;8:e3078 pubmed publisher
Yamakami Y, Kohashi K, Oyama K, Mohri Y, Hidema S, Nishimori K. LGR4 is required for sequential molar development. Biochem Biophys Rep. 2016;8:174-183 pubmed publisher
Pavlidou T, Rosina M, Fuoco C, Gerini G, Gargioli C, Castagnoli L, et al. Regulation of myoblast differentiation by metabolic perturbations induced by metformin. PLoS ONE. 2017;12:e0182475 pubmed publisher
Fishbein I, Guerrero D, Alferiev I, Foster J, Minutolo N, Chorny M, et al. Stent-based delivery of adeno-associated viral vectors with sustained vascular transduction and iNOS-mediated inhibition of in-stent restenosis. Gene Ther. 2017;24:717-726 pubmed publisher
Furukawa S, Nagaike M, Ozaki K. Databases for technical aspects of immunohistochemistry. J Toxicol Pathol. 2017;30:79-107 pubmed publisher
Kalliokoski S, Piqueras V, Frías R, Sulic A, Määttä J, Kähkönen N, et al. Transglutaminase 2-specific coeliac disease autoantibodies induce morphological changes and signs of inflammation in the small-bowel mucosa of mice. Amino Acids. 2017;49:529-540 pubmed publisher
Liang X, Luo M, Wei X, Ma C, Yang Y, Shao B, et al. A folate receptor-targeted lipoplex delivering interleukin-15 gene for colon cancer immunotherapy. Oncotarget. 2016;7:52207-52217 pubmed publisher
Steven A, Leisz S, Sychra K, Hiebl B, Wickenhauser C, Mougiakakos D, et al. Hypoxia-mediated alterations and their role in the HER-2/neuregulated CREB status and localization. Oncotarget. 2016;7:52061-52084 pubmed publisher
Yancu D, Blouin M, Birman E, Florianova L, Aleynikova O, Zakikhani M, et al. A phenotype of IGFBP-3 knockout mice revealed by dextran sulfate-induced colitis. J Gastroenterol Hepatol. 2017;32:146-153 pubmed publisher
Chen N, Chyau C, Lee Y, Tseng H, Chou F. Promotion of mitotic catastrophe via activation of PTEN by paclitaxel with supplement of mulberry water extract in bladder cancer cells. Sci Rep. 2016;6:20417 pubmed publisher
Katare R, Rawal S, Munasinghe P, Tsuchimochi H, Inagaki T, Fujii Y, et al. Ghrelin Promotes Functional Angiogenesis in a Mouse Model of Critical Limb Ischemia Through Activation of Proangiogenic MicroRNAs. Endocrinology. 2016;157:432-45 pubmed publisher
Velarde M, Demaria M, Melov S, Campisi J. Pleiotropic age-dependent effects of mitochondrial dysfunction on epidermal stem cells. Proc Natl Acad Sci U S A. 2015;112:10407-12 pubmed publisher
Nowak D, Cho H, Herzka T, Watrud K, DeMarco D, Wang V, et al. MYC Drives Pten/Trp53-Deficient Proliferation and Metastasis due to IL6 Secretion and AKT Suppression via PHLPP2. Cancer Discov. 2015;5:636-51 pubmed publisher
Franz H, Greschik H, Willmann D, Ozretić L, Jilg C, Wardelmann E, et al. The histone code reader SPIN1 controls RET signaling in liposarcoma. Oncotarget. 2015;6:4773-89 pubmed
Lindley L, Curtis K, Sánchez Mejías A, Rieger M, Robbins D, Briegel K. The WNT-controlled transcriptional regulator LBH is required for mammary stem cell expansion and maintenance of the basal lineage. Development. 2015;142:893-904 pubmed publisher
Zhou Y, Rychahou P, Wang Q, Weiss H, Evers B. TSC2/mTORC1 signaling controls Paneth and goblet cell differentiation in the intestinal epithelium. Cell Death Dis. 2015;6:e1631 pubmed publisher
Rachidi S, Sun S, Wu B, Jones E, Drake R, Ogretmen B, et al. Endoplasmic reticulum heat shock protein gp96 maintains liver homeostasis and promotes hepatocellular carcinogenesis. J Hepatol. 2015;62:879-88 pubmed publisher
Mathes A, Rice L, Affandi A, Dimarzio M, Rifkin I, Stifano G, et al. CpGB DNA activates dermal macrophages and specifically recruits inflammatory monocytes into the skin. Exp Dermatol. 2015;24:133-9 pubmed publisher
Beristain A, Molyneux S, Joshi P, Pomroy N, Di Grappa M, Chang M, et al. PKA signaling drives mammary tumorigenesis through Src. Oncogene. 2015;34:1160-73 pubmed publisher
product information
master code :
NB110-89717
SKU :
NB110-89717
product name :
Ki67/MKI67 Antibody - BSA Free
unit size :
0.1 ml (also 0.025 ml)
description :
The Ki67/MKI67 Antibody - BSA Free from Novus is a rabbit polyclonal antibody to Ki67/MKI67. This antibody reacts with human,mouse,porcine,rat,fish - danio rerio (zebrafish). The Ki67/MKI67 Antibody - BSA Free has been validated for the following applications: Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,IF/IHC,Flow Cytometry,Immunohistochemistry-Frozen,Immunocytochemistry/ Immunofluorescence,Flow (Intracellular),Knockout Validated.
target :
Ki67/MKI67
category :
Primary Antibodies
buffer :
PBS
clonality :
Polyclonal
concentration :
1 mg/ml
conjugate :
Unconjugated
host :
Rabbit
immunogen :
The immunogen for this KI67/MKI67 Antibody was made using a synthetic peptide from the internal region of Mouse KI67/MKI67, between aminoacids 1850-1950 (1899-1916) Uniprot# E9PVX6.
isotype :
IgG
purity :
Immunogen affinity purified
species :
Human,Mouse,Porcine,Rat,Fish - Danio rerio (Zebrafish)
theoretical molecular weight :
351 kDa
gene symbol :
MKI67
Antibody validation :
Knockout/Knockdown
accessionNumbers :
Q61769
applications :
Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,IF/IHC,Flow Cytometry,Immunohistochemistry-Frozen,Immunocytochemistry/ Immunofluorescence,Flow (Intracellular),Knockout Validated
USD :
469 USD
alt names :
antigen identified by monoclonal Ki-67, antigen KI-67, Antigen Ki67, Ki67, Ki-67, KIA, Marker Of Proliferation Ki-67, MIB-, MIB-1, PPP1R105, Proliferation Marker Protein Ki-67, proliferation-related Ki-67 antigen, Protein Phosphatase 1, Regulatory Subunit 105
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.