product summary
request information :
company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
Rabbit Polyclonal Mucolipin 1 Antibody
catalog :
NB110-82375R
quantity :
0.1 ml
price :
319 USD
clonality :
polyclonal
host :
rabbit
reactivity :
human, mouse, rat
application :
western blot
more info or order :
Novus Biologicals product webpage
product information
Catalog Number :
NB110-82375R
Product Name :
Rabbit Polyclonal Mucolipin 1 Antibody
List Price :
319 USD
Product Type :
Primary Antibodies
Package Size :
0.1 ml
AltNames :
MG-2, ML4TRP-ML1, MLIV, MST080, MSTP080, mucolipidin, Mucolipidin, mucolipidosis type IV protein, mucolipin 1, mucolipin-1, TRPML1, TRP-ML1, TRPM-L1
Background :
Defects in Mucolipin-1 are the cause of mucolipidosis type IV (MLIV), also known as sialolipidosis. MLIV is an autosomal recessive lysosomal storage disorder characterized by severe psychomotor retardation and ophthalmologic abnormalities, including corneal opacity, retinal degeneration and strabismus. Storage bodies of lipids and water-soluble substances are seen by electron microscopy in almost every cell type of the patients. Most patients are unable to speak or walk independently and reach a maximal developmental level of 1-2 years. All patients have constitutive achlorhydia associated with a secondary elevation of serum gastrin levels.
Buffer :
50mM sodium borate
Clonality :
Polyclonal
Concentration :
1.0 mg/ml
Conjugate :
DyLight 550
Application Summary :
Western Blot
Host :
Rabbit
Immunogen :
Synthetic peptide made to a C-terminal portion of mouse Mucolipin 1 (within residues 500-580). [Swiss-Prot# Q99J21]
Localization :
Cell membrane; Multi-pass membrane protein
Preservative :
No Preservative
Purity :
Immunogen affinity purified
CrossReactivity :
Human, mouse and rat. Immunogen sequence has 85% homology to monkey and 78% homology to bovine.
Storage :
Store at 4C in the dark.
TMW :
66 kDa
Uses :
This Mucolipin 1 antibody is useful for Western blot, where a band can be seen at ~66 kDa.
Research Area :
Cell Biology, Neuroscience, Sensory Systems, Signal Transduction, Vision
more info or order :
Novus Biologicals product webpage
company information
Novus Biologicals
8100 Southpark Way, A-8
Littleton, CO 80120
novus@novusbio.com
www.novusbio.com
3037301950
headquarters: USA
The mission of Novus Biologicals, LLC is to accelerate scientific discovery by developing and marketing unique products in the forefront of science. Novus Biologicals was organized to provide the biological research community with a mechanism for commercializing unique biological materials. We also focus on continually monitoring scientific trends and supply materials to serve these trends. By making these products widely available to institutional and commercial researchers, Novus Biologicals plays an important role in furthering biological research. All of Novus Biologicals products are supplied with detailed technical information and ongoing support. By serving niche and emerging markets, Novus Biologicals has become specialists in markets and has formed and will continue to form ongoing partnerships with our customers.