TRPM2 Antibody - BSA Free | Novus Biologicals NB110-81601 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

TRPM2 Antibody - BSA Free

catalog :

NB110-81601

quantity :

0.1 ml (also 0.025 ml)

price :

409 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Novus Biologicals product webpage

citations: 14

Reference
Sun K, Zhang X, Hou L, Lu F, Liu H, Zheng Z, et al. TRPM2-mediated feed-forward loop promotes chondrocyte damage in osteoarthritis via calcium-cGAS-STING-NF-κB pathway. J Adv Res. 2024;: pubmed publisher
Zong P, Feng J, Legere N, Li Y, Yue Z, Li C, et al. TRPM2 enhances ischemic excitotoxicity by associating with PKCγ. Cell Rep. 2024;43:113722 pubmed publisher
Rah S, Joe Y, Park J, Ryter S, Park C, Chung H, et al. CD38/ADP-ribose/TRPM2-mediated nuclear Ca2+ signaling is essential for hepatic gluconeogenesis in fasting and diabetes. Exp Mol Med. 2023;55:1492-1505 pubmed publisher
Yoshikawa C, Maegawa H, Usami N, Hanamoto H, Kudo C, Niwa H. Antagonist of transient receptor potential melastatin 2 suppresses mechanical hypersensitivity and activation of microglia induced by infraorbital nerve ligation in male rats. Biochem Biophys Res Commun. 2023;671:67-74 pubmed publisher
Zong P, Feng J, Yue Z, Yu A, Vacher J, Jellison E, et al. TRPM2 deficiency in mice protects against atherosclerosis by inhibiting TRPM2-CD36 inflammatory axis in macrophages. Nat Cardiovasc Res. 2022;1:344-360 pubmed publisher
Zong P, Feng J, Yue Z, Li Y, Wu G, Sun B, et al. Functional coupling of TRPM2 and extrasynaptic NMDARs exacerbates excitotoxicity in ischemic brain injury. Neuron. 2022;110:1944-1958.e8 pubmed publisher
Wang W, Yang Q, Zhou C, Jiang H, Sun Y, Wang H, et al. Transcriptomic changes in the hypothalamus of ovariectomized mice: Data from RNA-seq analysis. Ann Anat. 2022;241:151886 pubmed publisher
Ghosh P, Guo Y, Ashrafi A, Chen J, Dey S, Zhong S, et al. Oxygen-Enhanced Optoacoustic Tomography Reveals the Effectiveness of Targeting Heme and Oxidative Phosphorylation at Normalizing Tumor Vascular Oxygenation. Cancer Res. 2020;80:3542-3555 pubmed publisher
Iannielli A, Ugolini G, Cordiglieri C, Bido S, Rubio A, Colasante G, et al. Reconstitution of the Human Nigro-striatal Pathway on-a-Chip Reveals OPA1-Dependent Mitochondrial Defects and Loss of Dopaminergic Synapses. Cell Rep. 2019;29:4646-4656.e4 pubmed publisher
Sala D, Cunningham T, Stec M, Etxaniz U, Nicoletti C, Dall Agnese A, et al. The Stat3-Fam3a axis promotes muscle stem cell myogenic lineage progression by inducing mitochondrial respiration. Nat Commun. 2019;10:1796 pubmed publisher
Ward J, Stoyas C, Switonski P, Ichou F, Fan W, Collins B, et al. Metabolic and Organelle Morphology Defects in Mice and Human Patients Define Spinocerebellar Ataxia Type 7 as a Mitochondrial Disease. Cell Rep. 2019;26:1189-1202.e6 pubmed publisher
Yee A, Freestone P, Bai J, Lipski J. Paradoxical lower sensitivity of Locus Coeruleus than Substantia Nigra pars compacta neurons to acute actions of rotenone. Exp Neurol. 2017;287:34-43 pubmed publisher
Rah S, Kwak J, Chung Y, Kim U. ADP-ribose/TRPM2-mediated Ca2+ signaling is essential for cytolytic degranulation and antitumor activity of natural killer cells. Sci Rep. 2015;5:9482 pubmed publisher
Chung M, Asgar J, Lee J, Shim M, Dumler C, Ro J. The role of TRPM2 in hydrogen peroxide-induced expression of inflammatory cytokine and chemokine in rat trigeminal ganglia. Neuroscience. 2015;297:160-9 pubmed publisher

product information

master code :

NB110-81601

SKU :

NB110-81601

product name :

TRPM2 Antibody - BSA Free

unit size :

0.1 ml (also 0.025 ml)

description :

The TRPM2 Antibody - BSA Free from Novus is a rabbit polyclonal antibody to TRPM2. This antibody reacts with mouse,rat. The TRPM2 Antibody - BSA Free has been validated for the following applications: Western Blot,Immunocytochemistry/ Immunofluorescence,IF/IHC,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen.

target :

TRPM2

category :

Primary Antibodies

buffer :

PBS

clonality :

Polyclonal

concentration :

1.0 mg/ml

conjugate :

Unconjugated

host :

Rabbit

immunogen :

Synthetic peptide made to a C-terminal portion of the rat TRPM2 protein (within residues 1430-1508). [Swiss-Prot# Q5G856]

isotype :

IgG

purity :

Immunogen affinity purified

species :

Mouse,Rat

theoretical molecular weight :

181 kDa

gene symbol :

TRPM2

applications :

IF/IHC,Western Blot,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen

USD :

409 USD

alt names :

EC 3.6.1.13, EREG1MGC133383, Estrogen-responsive element-associated gene 1 protein, KNP3LTrpC-2, Long transient receptor potential channel 2, LTrpC2, LTRPC2TRPC7transient receptor potential cation channel subfamily M member 2, NUDT9H, NUDT9L1, transient receptor potential cation channel, subfamily M, member 2, Transient receptor potential channel 7, TrpC7

storage :

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

more info or order :

Novus Biologicals product webpage