product summary
request information :
company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
Rabbit Polyclonal EPS15 Antibody
catalog :
NB110-74688R
quantity :
0.2 ml
price :
479 USD
clonality :
polyclonal
host :
rabbit
reactivity :
mouse, human, rat
application :
immunoprecipitation, western blot, immunocytochemistry
more info or order :
Novus Biologicals product webpage
product information
Catalog Number :
NB110-74688R
Product Name :
Rabbit Polyclonal EPS15 Antibody
List Price :
479 USD
Product Type :
Primary Antibodies
Package Size :
0.2 ml
AltNames :
AF1P, AF-1P, ALL1 fused gene from chromosome 1, epidermal growth factor receptor pathway substrate 15, epidermal growth factor receptor substrate 15, MLLT5, Protein AF-1p, Protein Eps15
Background :
EPS15 is a ubiquitously expressed protein that is involved in cell growth regulation and may be involved in the regulation of mitogenic signals and control of cell proliferation. Phosphorylation of EPS15 on Tyrosine 849 upon DNA damage is involved in the internalization of EGFR. A chromosomal aberration involving EPS15 is also found in acute leukemias, resulting in a rogue activator protein.
Buffer :
50mM sodium borate
Clonality :
Polyclonal
Concentration :
0.3 mg/ml
Conjugate :
DyLight 550
Application Summary :
Western Blot, Immunocytochemistry/Immunofluorescence, Immunoprecipitation
Host :
Rabbit
Immunogen :
Synthetic peptide made to an internal portion of human EPS15 (within residues 460-560). [Swiss-Prot# P42566]
Localization :
Cytoplasmic. Recruited to the plasma membrane upon EGFR activation and localizes to coated pits.
Preservative :
No Preservative
Purity :
Immunogen affinity purified
CrossReactivity :
Human, mouse and rat.
Storage :
Store at 4C in the dark.
Swissprot Human :
P42566
TMW :
135 kDa
Uses :
This EPS15 antibody is useful for Immunocytochemistry/Immunofluorescence, Immunoprecipitation and Western blot analysis, where a band is seen at ~135 kDa.
Research Area :
Cell Biology, Signal Transduction
more info or order :
Novus Biologicals product webpage
company information
Novus Biologicals
8100 Southpark Way, A-8
Littleton, CO 80120
novus@novusbio.com
www.novusbio.com
3037301950
headquarters: USA
The mission of Novus Biologicals, LLC is to accelerate scientific discovery by developing and marketing unique products in the forefront of science. Novus Biologicals was organized to provide the biological research community with a mechanism for commercializing unique biological materials. We also focus on continually monitoring scientific trends and supply materials to serve these trends. By making these products widely available to institutional and commercial researchers, Novus Biologicals plays an important role in furthering biological research. All of Novus Biologicals products are supplied with detailed technical information and ongoing support. By serving niche and emerging markets, Novus Biologicals has become specialists in markets and has formed and will continue to form ongoing partnerships with our customers.