product summary
request information :
company name :
Novus Biologicals
product type :
antibody
product name :
Rabbit Polyclonal Caveolin 1 Antibody
catalog :
NB110-74687G
quantity :
0.1 ml
price :
399.00 USD
clonality :
polyclonal
host :
rabbit
reactivity :
human, rat, mouse
application :
western blot, immunoprecipitation, immunocytochemistry
more info or order :
product information
Catalog Number :
NB110-74687G
Product Name :
Rabbit Polyclonal Caveolin 1 Antibody
List Price :
399.00 USD
Product Type :
Primary Antibodies
Package Size :
0.1 ml
AltNames :
CAV, caveolae protein, 22kD, caveolin 1, caveolae protein, 22kDa, cell growth-inhibiting protein 32, MSTP085
Background :
Caveolae are specialized domains of the plasma membrane that are implicated in the sequestration of a variety of lipid and protein molecules. It has been suggested that these important cellular organelles have a pivotal role in such diverse biochemical processes as lipid metabolism, growth regulation, signal transduction, and apoptosis. Caveolin interacts with and regulates heterotrimeric G-proteins. Currently, there are three members of the caveolin multigene family which are known to encode 21-24 kDa integral membrane proteins that comprise the major structural component of the caveolar membrane in vivo. Caveolin-2 protein is abundantly expressed in fibroblasts and differentiated adipocytes, smooth and skeletal muscle, and endothelial cells. The expression of caveolin-1 is similar to that of caveolin-2 while caveolin-3 expression appears to be limited to muscle tissue types.
Buffer :
50mM sodium borate
Clonality :
Polyclonal
Concentration :
0.8 mg/ml
Conjugate :
DyLight 488
Application Summary :
Western Blot, Immunocytochemistry/Immunofluorescence, Immunoprecipitation
Host :
Rabbit
Immunogen :
Synthetic peptide made to an N-terminal portion of rat Caveolin 1 (within residues 1-150). [Swiss-Prot# P41350]
Localization :
Membrane
Marker :
Caveolae Marker, Endosome Marker
Preservative :
No Preservative
Purity :
Immunogen affinity purified
CrossReactivity :
Human, mouse and rat.
Storage :
Store at 4C in the dark.
TMW :
22 kDa
Uses :
This Caveolin 1 antibody is useful for Immunocytochemistry/Immunofluorescence, Western blot and Immunoprecipitation. In Western blot a band is seen ~22 kDa.
Research Area :
Cancer, Caveolae Markers, Cellular Markers, Cholesterol Metabolism, Hypoxia, Lipid and Metabolism, Lipid Droplets, Signal Transduction
more info or order :
company information
Novus Biologicals
8100 Southpark Way, A-8
Littleton, CO 80120
novus@novusbio.com
www.novusbio.com
3037301950
headquarters: usa
The mission of Novus Biologicals, LLC is to accelerate scientific discovery by developing and marketing unique products in the forefront of science. Novus Biologicals was organized to provide the biological research community with a mechanism for commercializing unique biological materials. We also focus on continually monitoring scientific trends and supply materials to serve these trends. By making these products widely available to institutional and commercial researchers, Novus Biologicals plays an important role in furthering biological research. All of Novus Biologicals products are supplied with detailed technical information and ongoing support. By serving niche and emerging markets, Novus Biologicals has become specialists in markets and has formed and will continue to form ongoing partnerships with our customers.