product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
HAP1 Antibody (1B6) - BSA Free
catalog :
NB110-74569
quantity :
0.1 ml (also 0.025 ml)
price :
409 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
1B6
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 9
Reference
Cason S, Carman P, Van Duyne C, Goldsmith J, Dominguez R, Holzbaur E. Sequential dynein effectors regulate axonal autophagosome motility in a maturation-dependent pathway. J Cell Biol. 2021;220: pubmed publisher
Gong Y, Feng Y, Cao Y, Zhao J, Wu W, Zheng Y, et al. Huntingtin-associated protein 1 plays an essential role in the pathogenesis of type 2 diabetes by regulating the translocation of GLUT4 in mouse adipocytes. BMJ Open Diabetes Res Care. 2020;8: pubmed publisher
Xiang J, Yang S, Xin N, Gaertig M, Reeves R, Li S, et al. DYRK1A regulates Hap1-Dcaf7/WDR68 binding with implication for delayed growth in Down syndrome. Proc Natl Acad Sci U S A. 2017;114:E1224-E1233 pubmed publisher
Corradini E, Burgers P, Plank M, Heck A, Scholten A. Huntingtin-associated protein 1 (HAP1) is a cGMP-dependent kinase anchoring protein (GKAP) specific for the cGMP-dependent protein kinase Iβ isoform. J Biol Chem. 2015;290:7887-96 pubmed publisher
Corradini E, Vallur R, Raaijmakers L, Feil S, Feil R, Heck A, et al. Alterations in the cerebellar (Phospho)proteome of a cyclic guanosine monophosphate (cGMP)-dependent protein kinase knockout mouse. Mol Cell Proteomics. 2014;13:2004-16 pubmed publisher
Tang T, Tu H, Chan E, Maximov A, Wang Z, Wellington C, et al. Huntingtin and huntingtin-associated protein 1 influence neuronal calcium signaling mediated by inositol-(1,4,5) triphosphate receptor type 1. Neuron. 2003;39:227-39 pubmed
Torre E, Coleman S, Yi H, Gutekunst C. A protocol for isolation and biochemical characterization of stigmoid bodies from rat brain. J Neurosci Methods. 2003;125:27-32 pubmed
Gutekunst C, Torre E, Sheng Z, Yi H, Coleman S, Riedel I, et al. Stigmoid bodies contain type I receptor proteins SorLA/LR11 and sortilin: new perspectives on their function. J Histochem Cytochem. 2003;51:841-52 pubmed
Chan E, Nasir J, Gutekunst C, Coleman S, Maclean A, Maas A, et al. Targeted disruption of Huntingtin-associated protein-1 (Hap1) results in postnatal death due to depressed feeding behavior. Hum Mol Genet. 2002;11:945-59 pubmed
product information
master code :
NB110-74569
SKU :
NB110-74569
product name :
HAP1 Antibody (1B6) - BSA Free
unit size :
0.1 ml (also 0.025 ml)
description :
The HAP1 Antibody (1B6) - BSA Free from Novus is a mouse monoclonal antibody to HAP1. This antibody reacts with human,mouse,rat. The HAP1 Antibody (1B6) - BSA Free has been validated for the following applications: Western Blot,IF/IHC,Immunoprecipitation,Immunocytochemistry/ Immunofluorescence,Flow Cytometry,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen.
target :
HAP1
category :
Primary Antibodies
buffer :
PBS and 50% Glycerol
clonality :
Monoclonal
clone :
1B6
concentration :
1 mg/ml
conjugate :
Unconjugated
host :
Mouse
immunogen :
Fusion protein from rat HAP1. [UniProt# P54256]
isotype :
IgG1
purity :
Protein G purified
species :
Human,Mouse,Rat
specificity :
This is specific for isoforms A and B
gene symbol :
HAP1
applications :
IF/IHC,Immunoprecipitation,Western Blot,Immunocytochemistry/ Immunofluorescence,Flow Cytometry,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen
USD :
409 USD
alt names :
HAP2huntingtin-associated protein 2, hHLP1, HIP5, HLP1, HLPHAP-1, huntingtin-associated protein 1, Neuroan 1
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.