product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
beta-Actin Antibody (AC-15) - BSA Free
catalog :
NB110-67828
quantity :
0.1 ml
price :
489 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
AC-15
reactivity :
human, mouse, rat, dogs, chicken, bovine
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - frozen section
more info or order :
citations: 27
Reference
Nonaka H, Kondo T, Suga M, Yamanaka R, Sagara Y, Tsukita K, et al. Induced pluripotent stem cell-based assays recapture multiple properties of human astrocytes. J Cell Mol Med. 2024;28:e18214 pubmed publisher
Lie P, Yoo L, Goulbourne C, Berg M, Stavrides P, Huo C, et al. Axonal transport of late endosomes and amphisomes is selectively modulated by local Ca2+ efflux and disrupted by PSEN1 loss of function. Sci Adv. 2022;8:eabj5716 pubmed publisher
Fossati S, Giannoni P, Solesio M, Cocklin S, Cabrera E, Ghiso J, et al. The carbonic anhydrase inhibitor methazolamide prevents amyloid beta-induced mitochondrial dysfunction and caspase activation protecting neuronal and glial cells in vitro and in the mouse brain. Neurobiol Dis. 2016;86:29-40 pubmed publisher
Cox J, Abdelrahman Y, Peters J, Naher N, Belland R. Chlamydia trachomatis utilizes the mammalian CLA1 lipid transporter to acquire host phosphatidylcholine essential for growth. Cell Microbiol. 2016;18:305-18 pubmed publisher
Moiseyev G, Nikolaeva O, Chen Y, Farjo K, Takahashi Y, Ma J. Inhibition of the visual cycle by A2E through direct interaction with RPE65 and implications in Stargardt disease. Proc Natl Acad Sci U S A. 2010;107:17551-6 pubmed publisher
Alejandro E, Johnson J. Inhibition of Raf-1 alters multiple downstream pathways to induce pancreatic beta-cell apoptosis. J Biol Chem. 2008;283:2407-17 pubmed
Greer E, Oskoui P, Banko M, Maniar J, Gygi M, Gygi S, et al. The energy sensor AMP-activated protein kinase directly regulates the mammalian FOXO3 transcription factor. J Biol Chem. 2007;282:30107-19 pubmed
Zhang S, Suvannasankha A, Crean C, White V, Johnson A, Chen C, et al. OSU-03012, a novel celecoxib derivative, is cytotoxic to myeloma cells and acts through multiple mechanisms. Clin Cancer Res. 2007;13:4750-8 pubmed
Ougolkov A, Bone N, Fernandez Zapico M, Kay N, Billadeau D. Inhibition of glycogen synthase kinase-3 activity leads to epigenetic silencing of nuclear factor kappaB target genes and induction of apoptosis in chronic lymphocytic leukemia B cells. Blood. 2007;110:735-42 pubmed
Park K, Hallows J, Chakrabarty P, Davies P, Vincent I. Conditional neuronal simian virus 40 T antigen expression induces Alzheimer-like tau and amyloid pathology in mice. J Neurosci. 2007;27:2969-78 pubmed
Dennis V, Jefferson A, Singh S, Ganapamo F, Philipp M. Interleukin-10 anti-inflammatory response to Borrelia burgdorferi, the agent of Lyme disease: a possible role for suppressors of cytokine signaling 1 and 3. Infect Immun. 2006;74:5780-9 pubmed
Abramovich D, Parborell F, Tesone M. Effect of a vascular endothelial growth factor (VEGF) inhibitory treatment on the folliculogenesis and ovarian apoptosis in gonadotropin-treated prepubertal rats. Biol Reprod. 2006;75:434-41 pubmed
Rice P, Peters S, Beard K, Ahnen D. Sulindac independently modulates extracellular signal-regulated kinase 1/2 and cyclic GMP-dependent protein kinase signaling pathways. Mol Cancer Ther. 2006;5:746-54 pubmed
Csiszar A, Ahmad M, Smith K, Labinskyy N, Gao Q, Kaley G, et al. Bone morphogenetic protein-2 induces proinflammatory endothelial phenotype. Am J Pathol. 2006;168:629-38 pubmed
Liu X, Manser T. Antinuclear antigen B cells that down-regulate surface B cell receptor during development to mature, follicular phenotype do not display features of anergy in vitro. J Immunol. 2005;174:4505-15 pubmed
Sung S, Yang H, Uryu K, Lee E, Zhao L, Shineman D, et al. Modulation of nuclear factor-kappa B activity by indomethacin influences A beta levels but not A beta precursor protein metabolism in a model of Alzheimer's disease. Am J Pathol. 2004;165:2197-206 pubmed
Adler S, Huang H. Oxidant stress in kidneys of spontaneously hypertensive rats involves both oxidase overexpression and loss of extracellular superoxide dismutase. Am J Physiol Renal Physiol. 2004;287:F907-13 pubmed
Chong V, Costain W, Marriott J, Sindwani S, Knauer D, Wang J, et al. Differential display polymerase chain reaction reveals increased expression of striatal rat glia-derived nexin following chronic clozapine treatment. Pharmacogenomics J. 2004;4:379-87 pubmed
Mukherjee P, Abate L, Seyfried T. Antiangiogenic and proapoptotic effects of dietary restriction on experimental mouse and human brain tumors. Clin Cancer Res. 2004;10:5622-9 pubmed
Laughlin R, McGugan G, Powell R, Welter B, Temesvari L. Involvement of raft-like plasma membrane domains of Entamoeba histolytica in pinocytosis and adhesion. Infect Immun. 2004;72:5349-57 pubmed
Watters J, Kraja A, Meucci M, Province M, McLeod H. Genome-wide discovery of loci influencing chemotherapy cytotoxicity. Proc Natl Acad Sci U S A. 2004;101:11809-14 pubmed
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Liao J, Xu X, Wargovich M. Direct reprobing with anti-beta-actin antibody as an internal control for western blotting analysis. Biotechniques. 2000;28:216-8 pubmed
product information
master code :
NB110-67828
SKU :
NB110-67828
product name :
beta-Actin Antibody (AC-15) - BSA Free
unit size :
0.1 ml
description :
The beta-Actin Antibody (AC-15) - BSA Free from Novus is a mouse monoclonal antibody to beta-Actin. This antibody reacts with bovine,canine,chicken,drosophila (negative),feline,fish,guinea pig,hamster,human,leech,mammal,mouse,porcine,primate,rabbit,rat,sheep,squirrel,turkey,zebrafish. The beta-Actin Antibody (AC-15) - BSA Free has been validated for the following applications: Simple Western,Western Blot,Flow Cytometry,Immunohistochemistry,Immunohistochemistry-Frozen,Microarray,Knockout Validated,Knockdown Validated,Immunocytochemistry/ Immunofluorescence.
target :
beta-Actin
category :
Primary Antibodies
buffer :
10mM PBS (pH 7.4)
clonality :
Monoclonal
clone :
AC-15
concentration :
1.0 mg/ml
conjugate :
Unconjugated
host :
Mouse
immunogen :
This beta-Actin Antibody (AC-15) was made to a slightly modified Beta-cytoplasmic actin N-terminal peptide, Ac-Asp-Asp-Asp-Ile-Ala-Ala-Leu-Val-Ile-Asp-Asn-Gly-Ser-Gly-Lys, conjugated to KLH.
isotype :
IgG1
purity :
Protein A or G purified
species :
Bovine,Canine,Chicken,Drosophila (Negative),Feline,Fish,Guinea Pig,Hamster,Human,Leech,Mammal,Mouse,Porcine,Primate,Rabbit,Rat,Sheep,Squirrel,Turkey,Zebrafish
specificity :
Beta-actin (AC-15)
theoretical molecular weight :
42 kDa
gene symbol :
ACTB
applications :
Simple Western,Western Blot,Flow Cytometry,Immunohistochemistry,Immunohistochemistry-Frozen,Microarray,Knockout Validated,Knockdown Validated,Immunocytochemistry/ Immunofluorescence
USD :
489 USD
alt names :
ACTB, actin, beta, actin, cytoplasmic 1, B-Actin, Beta Actin, beta cytoskeletal actin, Beta-actin, BRWS1, I(2)-Actin, PS1TP5-binding protein 1, PS1TP5BP1
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.