product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
NPM1 Antibody - BSA Free
catalog :
NB110-61646
quantity :
0.1 ml (also 0.025 ml)
price :
409 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
HS23
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section
more info or order :
citations: 12
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; loading ...; fig 1f
Li Y, Ivica N, Dong T, Papageorgiou D, He Y, Brown D, et al. MFSD7C switches mitochondrial ATP synthesis to thermogenesis in response to heme. Nat Commun. 2020;11:4837 pubmed publisher
Wang X, Fan D, Han Q, Liu Y, Miao H, Wang X, et al. Mutant NPM1 Hijacks Transcriptional Hubs to Maintain Pathogenic Gene Programs in Acute Myeloid Leukemia. Cancer Discov. 2023;13:724-745 pubmed publisher
El Gamal R, Hashem A, Habashy D, Abou Elwafa M, Boshnak N. Flow cytometry in detection of Nucleophosmin 1 mutation in acute myeloid leukemia patients: A reproducible tertiary hospital experience. Int J Lab Hematol. 2020;: pubmed publisher
Huang H, Holub C, Rolzin P, Bilakovics J, Fanjul A, Satomi Y, et al. MetAP2 inhibition increases energy expenditure through direct action on brown adipocytes. J Biol Chem. 2019;294:9567-9575 pubmed publisher
Fujii K, Susanto T, Saurabh S, Barna M. Decoding the Function of Expansion Segments in Ribosomes. Mol Cell. 2018;72:1013-1020.e6 pubmed publisher
Zhang W, Zhao C, Zhao J, Zhu Y, Weng X, Chen Q, et al. Inactivation of PBX3 and HOXA9 by down-regulating H3K79 methylation represses NPM1-mutated leukemic cell survival. Theranostics. 2018;8:4359-4371 pubmed publisher
Jonckheere V, FijaƂkowska D, Van Damme P. Omics Assisted N-terminal Proteoform and Protein Expression Profiling On Methionine Aminopeptidase 1 (MetAP1) Deletion. Mol Cell Proteomics. 2018;17:694-708 pubmed publisher
Kleppe R, Rosati S, Jorge Finnigan A, Alvira S, Ghorbani S, Haavik J, et al. Phosphorylation dependence and stoichiometry of the complex formed by tyrosine hydroxylase and 14-3-3?. Mol Cell Proteomics. 2014;13:2017-30 pubmed publisher
Zhang F, Bhat S, Gabelli S, Chen X, Miller M, Nacev B, et al. Pyridinylquinazolines selectively inhibit human methionine aminopeptidase-1 in cells. J Med Chem. 2013;56:3996-4016 pubmed publisher
Bhat S, Shim J, Zhang F, Chong C, Liu J. Substituted oxines inhibit endothelial cell proliferation and angiogenesis. Org Biomol Chem. 2012;10:2979-92 pubmed publisher
Shim J, Matsui Y, Bhat S, Nacev B, Xu J, Bhang H, et al. Effect of nitroxoline on angiogenesis and growth of human bladder cancer. J Natl Cancer Inst. 2010;102:1855-73 pubmed publisher
Hu X, Addlagatta A, Lu J, Matthews B, Liu J. Elucidation of the function of type 1 human methionine aminopeptidase during cell cycle progression. Proc Natl Acad Sci U S A. 2006;103:18148-53 pubmed
product information
master code :
NB110-61646
SKU :
NB110-61646
product name :
NPM1 Antibody - BSA Free
unit size :
0.1 ml (also 0.025 ml)
description :
The NPM1 Antibody - BSA Free from Novus is a rabbit polyclonal antibody to NPM1. This antibody reacts with human,mouse. The NPM1 Antibody - BSA Free has been validated for the following applications: Immunoprecipitation,Western Blot,Immunocytochemistry/ Immunofluorescence,Flow Cytometry,Immunohistochemistry,Immunohistochemistry-Paraffin.
target :
NPM1
category :
Primary Antibodies
buffer :
PBS (pH 7.4)
clonality :
Polyclonal
concentration :
1.0 mg/ml
conjugate :
Unconjugated
host :
Rabbit
immunogen :
A synthetic peptide made to a C-terminal region of human mutant Nucleophosmin (within residues 250-294). [Accession# AAW67752]
isotype :
IgG
purity :
Immunogen affinity purified
species :
Human,Mouse
specificity :
This antibody is specific for the mutant form of Nucleophosmin
theoretical molecular weight :
37 kDa
gene symbol :
NPM1
applications :
Immunoprecipitation,Western Blot,Immunocytochemistry/ Immunofluorescence,Flow Cytometry,Immunohistochemistry,Immunohistochemistry-Paraffin
USD :
409 USD
alt names :
B23, MGC104254, NPMnucleophosmin/nucleoplasmin family, member 1, Nucleolar phosphoprotein B23, Nucleolar protein NO38, nucleophosmin, nucleophosmin (nucleolar phosphoprotein B23, numatrin), numatrin
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.