product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
DUOX2 Antibody - BSA Free
catalog :
NB110-61576
quantity :
0.1 ml (also 0.025 ml)
price :
399 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
P4C10
reactivity :
human, mouse, rat, dogs
application :
western blot, immunohistochemistry, immunocytochemistry, neutralization, immunohistochemistry - paraffin section
more info or order :
citations: 17
Published Application/Species/Sample/DilutionReference
  • western blot; human; fig 4m
Mota M, Metge B, Hinshaw D, Alsheikh H, Chen D, Samant R, et al. Merlin deficiency alters the redox management program in breast cancer. Mol Oncol. 2021;15:942-956 pubmed publisher
  • western blot; mouse; 1:500; loading ...; fig 3
Dyikanov D, Vasiluev P, Rysenkova K, Aleksandrushkina N, Tyurin Kuzmin P, Kulebyakin K, et al. Optimization of CRISPR/Cas9 technology to knock-out genes of interest in aneuploid cell lines. Tissue Eng Part C Methods. 2019;: pubmed publisher
Poinsignon L, Chissey A, Ajjaji A, Hernandez I, Vignaud M, Ferecatu I, et al. Placental cartography of NADPH oxidase (NOX) family proteins: Involvement in the pathophysiology of preeclampsia. Arch Biochem Biophys. 2023;749:109787 pubmed publisher
Zhou Y, Lu X, Chen H, Wang X, Cheng W, Zhang Q, et al. Single-cell Transcriptomics Reveals Early Molecular and Immune Alterations Underlying the Serrated Neoplasia Pathway Toward Colorectal Cancer. Cell Mol Gastroenterol Hepatol. 2023;15:393-424 pubmed publisher
Lee H, Ryu H, Park H, Yu J, Yoo G, Choi C, et al. Dual Oxidase 2 (DUOX2) as a Proteomic Biomarker for Predicting Treatment Response to Chemoradiation Therapy for Locally Advanced Rectal Cancer: Using High-Throughput Proteomic Analysis and Machine Learning Algorithm. Int J Mol Sci. 2022;23: pubmed publisher
Tang H, Liang T, Zhou Y, Ju H, Song D, Fang H. Telocytes reduce oxidative stress by downregulating DUOX2 expression in inflamed lungs of mice. Acta Biochim Biophys Sin (Shanghai). 2022;54:574-582 pubmed publisher
Yang M, Zhao Y, Ding Y, Wang J, Tan Y, Xu D, et al. A truncated protein product of the germline variant of the DUOX2 gene leads to adenomatous polyposis. Cancer Biol Med. 2021;18:215-226 pubmed publisher
Lv Q, Xu D, Ma J, Wang Y, Yang X, Zhao P, et al. Uric acid drives intestinal barrier dysfunction through TSPO-mediated NLRP3 inflammasome activation. Inflamm Res. 2021;70:127-137 pubmed publisher
Shen L, Ke Q, Chai J, Zhang C, Qiu L, Peng F, et al. PAG1 promotes the inherent radioresistance of laryngeal cancer cells via activation of STAT3. Exp Cell Res. 2018;370:127-136 pubmed publisher
Li S, Xiong N, Peng Y, Tang K, Bai H, Lv X, et al. Acidic pHe regulates cytoskeletal dynamics through conformational integrin ?1 activation and promotes membrane protrusion. Biochim Biophys Acta Mol Basis Dis. 2018;1864:2395-2408 pubmed publisher
Pinnington S, Marshall J, Wheeler A. Correlative 3D Structured Illumination Microscopy and Single-Molecule Localization Microscopy for Imaging Cancer Invasion. Methods Mol Biol. 2018;1764:253-265 pubmed publisher
Jafari N, Kim H, Park R, Li L, Jang M, Morris A, et al. CRISPR-Cas9 Mediated NOX4 Knockout Inhibits Cell Proliferation and Invasion in HeLa Cells. PLoS ONE. 2017;12:e0170327 pubmed publisher
Fan D, Takawale A, Shen M, Samokhvalov V, Basu R, Patel V, et al. A Disintegrin and Metalloprotease-17 Regulates Pressure Overload-Induced Myocardial Hypertrophy and Dysfunction Through Proteolytic Processing of Integrin ?1. Hypertension. 2016;68:937-48 pubmed publisher
Tyurin Kuzmin P, Zhdanovskaya N, Sukhova A, Sagaradze G, Albert E, Ageeva L, et al. Nox4 and Duox1/2 Mediate Redox Activation of Mesenchymal Cell Migration by PDGF. PLoS ONE. 2016;11:e0154157 pubmed publisher
Wakatsuki S, Furuno A, Ohshima M, Araki T. Oxidative stress-dependent phosphorylation activates ZNRF1 to induce neuronal/axonal degeneration. J Cell Biol. 2015;211:881-96 pubmed publisher
Beauséjour M, Noël D, Thibodeau S, Bouchard V, Harnois C, Beaulieu J, et al. Integrin/Fak/Src-mediated regulation of cell survival and anoikis in human intestinal epithelial crypt cells: selective engagement and roles of PI3-K isoform complexes. Apoptosis. 2012;17:566-78 pubmed publisher
Li E, Brown S, Stupack D, Puente X, Cheresh D, Nemerow G. Integrin alpha(v)beta1 is an adenovirus coreceptor. J Virol. 2001;75:5405-9 pubmed
product information
master code :
NB110-61576
SKU :
NB110-61576
product name :
DUOX2 Antibody - BSA Free
unit size :
0.1 ml (also 0.025 ml)
description :
The DUOX2 Antibody - BSA Free from Novus is a rabbit polyclonal antibody to DUOX2. This antibody reacts with canine,human,mouse,porcine,rat. The DUOX2 Antibody - BSA Free has been validated for the following applications: Western Blot,Immunohistochemistry,Immunohistochemistry-Paraffin,Block/Neutralize,Immunocytochemistry/ Immunofluorescence,Knockdown Validated.
target :
DUOX2
category :
Primary Antibodies
buffer :
PBS
clonality :
Polyclonal
concentration :
1.0 mg/ml
conjugate :
Unconjugated
host :
Rabbit
immunogen :
Synthetic peptide made to an internal portion of human DUOX2 (within residues 400-500). [Swiss-Prot# Q9NRD8]
isotype :
IgG
purity :
Immunogen affinity purified
species :
Canine,Human,Mouse,Porcine,Rat
gene symbol :
DUOX2
Antibody validation :
Knockout/Knockdown
applications :
Western Blot,Immunohistochemistry,Immunohistochemistry-Paraffin,Block/Neutralize,Immunocytochemistry/ Immunofluorescence,Knockdown Validated
USD :
399 USD
alt names :
dual oxidase 2, dual oxidase-like domains 2, EC 1.11.1.-, EC 1.6.3.1, flavoprotein NADPH oxidase, Large NOX 2, LNOX2P138(TOX), Long NOX 2, NADH/NADPH thyroid oxidase p138-tox, NADPH oxidase/peroxidase DUOX2, NADPH thyroid oxidase 2, nicotinamide adenine dinucleotide phosphate oxidase, NOXEF2, p138 thyroid oxidase, P138-TOX, THOX2TDH6, Thyroid oxidase 2
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.