product summary
request information :
company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
Rabbit Polyclonal Gastric Lipase Antibody
catalog :
NB110-60930F
quantity :
0.1 ml
price :
299.00 USD
clonality :
polyclonal
host :
rabbit
conjugate :
FITC
reactivity :
human, mouse, dog
application :
western blot
more info or order :
Novus Biologicals product webpage
product information
Catalog Number :
NB110-60930F
Product Name :
Rabbit Polyclonal Gastric Lipase Antibody
List Price :
299.00 USD
Product Type :
Primary Antibodies
Package Size :
0.1 ml
AltNames :
EC 3.1.1, EC 3.1.1.3, Gastric lipase, gastric triacylglycerol lipase, GL, HGL, HLAL, lipase, gastric, MGC138477, MGC142271
Background :
Gastric lipase (GL/LIPF or gastric triacylglycerol lipase) is an extremophilic enzyme which retains its activity in gastric juices fully at pH 2 under the presence of pepsin in stomach wherein the gastrointestinal lipolysis of dietary fat is initiated. Gastric lipase belongs to AB hydrolase superfamily/lipase family and is a secreted protein which is not inhibited by bile salts in the gastrointestinal tract, whereas pancreatic lipase (main lipase involved in fat digestion) requires a cofactor, namely colipase, to counteract the inhibitory effects of bile salts on lipase adsorption at lipid-water interfaces. Due to its acid resistant properties, it has been proposed as a candidate for the treatment of pancreatic enzyme insufficiency observed in chronic pancreatitis and cystic fibrosis, the gastrointestinal disorders which are characterized by exocrine pancreatic secretion deficiency, gastric acid secretion not being neutralized by pancreatic bicarbonate, and pH of the small intestine contents reaching as low as 2-3.
Buffer :
50mM sodium borate
Clonality :
Polyclonal
Conjugate :
FITC
Application Summary :
Western Blot
Host :
Rabbit
Immunogen :
A synthetic peptide within residues 1-100 of human Gastric Lipase. [Swiss-Prot# P07098]
Localization :
Secreted
Preservative :
No Preservative
Purity :
Immunogen affinity purified
CrossReactivity :
Human and mouse. Immunogen sequence has 87% homology to canine.
Storage :
Store at 4C in the dark.
Swissprot Human :
P07098
TMW :
45 kDa
Uses :
This Gastric Lipase antibody is useful for Western blot analysis, where a band is seen at ~45 kDa.
Research Area :
Autophagy, Cholesterol Metabolism, Chromatin Research, Diabetes Research, Endothelial Cell Markers, Glia Markers, Growth and Development, Lipid and Metabolism, Neuronal Cell Markers, Neuroscience, Oligodendrocyte Cell Markers, Signal Transduction
more info or order :
Novus Biologicals product webpage
company information
Novus Biologicals
8100 Southpark Way, A-8
Littleton, CO 80120
novus@novusbio.com
www.novusbio.com
3037301950
headquarters: USA
The mission of Novus Biologicals, LLC is to accelerate scientific discovery by developing and marketing unique products in the forefront of science. Novus Biologicals was organized to provide the biological research community with a mechanism for commercializing unique biological materials. We also focus on continually monitoring scientific trends and supply materials to serve these trends. By making these products widely available to institutional and commercial researchers, Novus Biologicals plays an important role in furthering biological research. All of Novus Biologicals products are supplied with detailed technical information and ongoing support. By serving niche and emerging markets, Novus Biologicals has become specialists in markets and has formed and will continue to form ongoing partnerships with our customers.