product summary
request information :
company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
Mouse Monoclonal Dopamine D5 R/DRD5 Antibody
catalog :
NB110-60019H
quantity :
0.1 ml
price :
309.00 USD
clonality :
monoclonal
host :
mouse
conjugate :
HRP
reactivity :
human, mouse, rat
application :
western blot
more info or order :
Novus Biologicals product webpage
product information
Catalog Number :
NB110-60019H
Product Name :
Mouse Monoclonal Dopamine D5 R/DRD5 Antibody
List Price :
309.00 USD
Product Type :
Primary Antibodies
Package Size :
0.1 ml
AltNames :
D(1B) dopamine receptor, D(5) dopamine receptor, D1beta dopamine receptor, Dopamine D5 receptor, dopamine receptor D1B, dopamine receptor D5, DRD1BDBDR, DRD1L2MGC10601
Background :
The members of the G protein-coupled receptor family are distinguished by their slow transmitting response to ligand binding. These seven transmembrane proteins include the adrenergic, serotonin, and dopamine receptors. The effect of the signaling molecule can be excitatory or inhibitory depending on the type of receptor to which it binds. Beta-adrenergic receptor bound to adrenaline activates adenylyl cyclase, while alpha 2-adrenergic receptor bound to adrenaline inhibits adenylyl cyclase. The dopamine receptors are divided into two classes; D1 and D2, which differ in their functional characteristics. D1 receptors stimulate adenylyl cyclase, while D2 receptors inhibit adenylyl cyclase activity. Five different subtypes of dopamine receptor have been described to date. D1DR and D5DR belong to the D1 subclass, while D2DR, D3DR and D4DR belong to the D2 subclass of dopamine receptors.
Buffer :
PBS
Clonality :
Monoclonal
Clone :
SG4-D1b
Conjugate :
HRP
Application Summary :
Western Blot
Host :
Mouse
Immunogen :
Recombinant rat Dopamine Receptor D5 (within the last 118 residues of the C-terminus). [Swiss-Prot# P25115]
Isotype :
IgG1 Kappa
Localization :
Cell membrane; Multi-pass membrane protein.
Preservative :
No Preservative
Purity :
Protein A purified
CrossReactivity :
Rat. Reactivity with mouse has had mixed results. It does not react with human protein.
Storage :
Store at 4C in the dark.
Uses :
This Dopamine Receptor D5 antibody is useful for Immunocytochemistry/Immunofluorescence, Western Blot and Immunohistochemistry. In Western Blot a band is seen ~52-64 kDa in SF9 cell lysate. There is no band in striatal tissue lysate. Do NOT boil samples.
Research Area :
Cancer, GPCR, Neuroscience, Neurotransmission, Signal Transduction
more info or order :
Novus Biologicals product webpage
company information
Novus Biologicals
8100 Southpark Way, A-8
Littleton, CO 80120
novus@novusbio.com
www.novusbio.com
3037301950
headquarters: USA
The mission of Novus Biologicals, LLC is to accelerate scientific discovery by developing and marketing unique products in the forefront of science. Novus Biologicals was organized to provide the biological research community with a mechanism for commercializing unique biological materials. We also focus on continually monitoring scientific trends and supply materials to serve these trends. By making these products widely available to institutional and commercial researchers, Novus Biologicals plays an important role in furthering biological research. All of Novus Biologicals products are supplied with detailed technical information and ongoing support. By serving niche and emerging markets, Novus Biologicals has become specialists in markets and has formed and will continue to form ongoing partnerships with our customers.