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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
WT1 Antibody (6F-H2) - BSA Free
catalog :
NB110-60011
quantity :
0.1 ml (also 0.025 ml)
price :
429 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
6F-H2
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 22
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; rat; 1:50; loading ...; fig s7a
  • immunohistochemistry; mouse; 1:50; fig s8c
Wang M, Xiong L, Jiang L, Lu Y, Liu F, Song L, et al. miR-4739 mediates pleural fibrosis by targeting bone morphogenetic protein 7. EBioMedicine. 2019;41:670-682 pubmed publisher
  • western blot; human
McCarty G, Loeb D. Hypoxia-sensitive epigenetic regulation of an antisense-oriented lncRNA controls WT1 expression in myeloid leukemia cells. PLoS ONE. 2015;10:e0119837 pubmed publisher
  • western blot; human; 1:400; loading ...; fig 2e
Jeitany M, Pineda J, Liu Q, Porreca R, Hoffschir F, Desmaze C, et al. A preclinical mouse model of glioma with an alternative mechanism of telomere maintenance (ALT). Int J Cancer. 2015;136:1546-58 pubmed publisher
Miyazaki Y, Orisaka M, Fujita Y, Mizutani T, Yazawa T, Yoshida Y. Steroidogenic differentiation of human amniotic membrane-derived mesenchymal stem cells into a progesterone-/androgen-producing cell lineage by SF-1 and an estrogen-producing cell lineage by WT1-KTS. Front Endocrinol (Lausanne). 2024;15:1410433 pubmed publisher
Yang X, Chen Z, Luo Z, Yang D, Hao Y, Hu J, et al. STING deletion alleviates podocyte injury through suppressing inflammation by targeting NLRP3 in diabetic kidney disease. Cell Signal. 2023;109:110777 pubmed publisher
Hu J, Zhang Z, Hu H, Yang K, Zhu Z, Yang Q, et al. LRH-1 activation alleviates diabetes-induced podocyte injury by promoting GLS2-mediated glutaminolysis. Cell Prolif. 2023;56:e13479 pubmed publisher
Medina Rangel P, Cross E, Liu C, Pedigo C, Tian X, Guti xe9 rrez Calabr xe9 s E, et al. Cell Cycle and Senescence Regulation by Podocyte Histone Deacetylase 1 and 2. J Am Soc Nephrol. 2023;34:433-450 pubmed publisher
Cao Y, Chen Z, Hu J, Feng J, Zhu Z, Fan Y, et al. Mfn2 Regulates High Glucose-Induced MAMs Dysfunction and Apoptosis in Podocytes via PERK Pathway. Front Cell Dev Biol. 2021;9:769213 pubmed publisher
Loubalova Z, Fulka H, Horvat F, Pasulka J, Malik R, Hirose M, et al. Formation of spermatogonia and fertile oocytes in golden hamsters requires piRNAs. Nat Cell Biol. 2021;23:992-1001 pubmed publisher
Liu L, Chen M, Lin K, Xiang X, Zheng Y, Zhu S. Inhibiting Caspase-12 Mediated Inflammasome Activation protects against Oxygen-Glucose Deprivation Injury in Primary Astrocytes. Int J Med Sci. 2020;17:1936-1945 pubmed publisher
Pruett N, Singh A, Shankar A, Schrump D, Hoang C. Normal mesothelial cell lines newly derived from human pleural biopsy explants. Am J Physiol Lung Cell Mol Physiol. 2020;319:L652-L660 pubmed publisher
Merlo S, Luaces J, Spampinato S, Toro Urrego N, Caruso G, D Amico F, et al. SIRT1 Mediates Melatonin's Effects on Microglial Activation in Hypoxia: In Vitro and In Vivo Evidence. Biomolecules. 2020;10: pubmed publisher
Hirshman N, Hughes F, Jin H, Harrison W, White S, Doan I, et al. Cyclophosphamide-induced cystitis results in NLRP3-mediated inflammation in the hippocampus and symptoms of depression in rats. Am J Physiol Renal Physiol. 2020;318:F354-F362 pubmed publisher
Xu C, Diao Y, Wang J, Xu H, Zhao M, Luan Z, et al. Intravenously infusing the secretome of adipose-derived mesenchymal stem cells ameliorates neuroinflammation and neurological functioning after traumatic brain injury. Stem Cells Dev. 2019;: pubmed publisher
Han T, Root J, Reyes L, Huchinson E, Hoffmann J, Lee W, et al. Human GNPTAB stuttering mutations engineered into mice cause vocalization deficits and astrocyte pathology in the corpus callosum. Proc Natl Acad Sci U S A. 2019;116:17515-17524 pubmed publisher
Gurung S, Reuter N, Preno A, Dubaut J, Nadeau H, Hyatt K, et al. Zika virus infection at mid-gestation results in fetal cerebral cortical injury and fetal death in the olive baboon. PLoS Pathog. 2019;15:e1007507 pubmed publisher
Horne S, Vasquez J, Guo Y, Ly V, Piret S, Leonardo A, et al. Podocyte-Specific Loss of Krüppel-Like Factor 6 Increases Mitochondrial Injury in Diabetic Kidney Disease. Diabetes. 2018;67:2420-2433 pubmed publisher
Merlo S, Spampinato S, Beneventano M, Sortino M. The contribution of microglia to early synaptic compensatory responses that precede β-amyloid-induced neuronal death. Sci Rep. 2018;8:7297 pubmed publisher
Yang H, Fu Y, Liu X, Shahi P, Mavlyutov T, Li J, et al. Role of the sigma-1 receptor chaperone in rod and cone photoreceptor degenerations in a mouse model of retinitis pigmentosa. Mol Neurodegener. 2017;12:68 pubmed publisher
Fan Y, Li X, Xiao W, Fu J, Harris R, Lindenmeyer M, et al. BAMBI elimination enhances alternative TGF-β signaling and glomerular dysfunction in diabetic mice. Diabetes. 2015;64:2220-33 pubmed publisher
McCarty G, Awad O, Loeb D. WT1 protein directly regulates expression of vascular endothelial growth factor and is a mediator of tumor response to hypoxia. J Biol Chem. 2011;286:43634-43 pubmed publisher
Rauscher F, Morris J, Fredericks W, Lopez Guisa J, Balakrishnan C, Jost M, et al. Characterization of monoclonal antibodies directed to the amino-terminus of the WT1, Wilms' tumor suppressor protein. Hybridoma. 1998;17:191-8 pubmed
product information
master code :
NB110-60011
SKU :
NB110-60011
product name :
WT1 Antibody (6F-H2) - BSA Free
unit size :
0.1 ml (also 0.025 ml)
description :
The WT1 Antibody (6F-H2) - BSA Free from Novus is a mouse monoclonal antibody to WT1. This antibody reacts with hamster,human,mouse. The WT1 Antibody (6F-H2) - BSA Free has been validated for the following applications: Immunohistochemistry,Immunocytochemistry/ Immunofluorescence,Western Blot,Immunoprecipitation,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Simple Western.
target :
WT1
category :
Primary Antibodies
buffer :
PBS
clonality :
Monoclonal
clone :
6F-H2
concentration :
1.0 mg/ml
conjugate :
Unconjugated
host :
Mouse
immunogen :
Human recombinant Wilms Tumor 1 protein (WT1) (residues 1-181). [Swiss-Prot: P19544]
isotype :
IgG1 Kappa
purity :
Protein G purified
species :
Hamster,Human,Mouse
theoretical molecular weight :
55 kDa
gene symbol :
WT1
applications :
Immunohistochemistry,Immunocytochemistry/ Immunofluorescence,Western Blot,Immunoprecipitation,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Simple Western
USD :
429 USD
alt names :
AWT1, NPHS4GUD, WAGR, Wilms tumor 1, Wilms tumor protein, WIT-2, WT33
storage :
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.