Defensin alpha 5 Antibody (8C8) - BSA Free | Novus Biologicals NB110-60002 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

Defensin alpha 5 Antibody (8C8) - BSA Free

catalog :

NB110-60002

quantity :

0.1 ml (also 0.025 ml)

price :

409 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

8C8

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, dot blot

more info or order :

Novus Biologicals product webpage

citations: 19

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; human; loading ...; fig 5p	Múnera J, Sundaram N, Rankin S, Hill D, Watson C, Mahe M, et al. Differentiation of Human Pluripotent Stem Cells into Colonic Organoids via Transient Activation of BMP Signaling. Cell Stem Cell. 2017;21:51-64.e6 pubmed publisher
western blot; human	Jung J, Kim H, Yeom J, Yoo C, Shin J, Yoo J, et al. Lowered expression of galectin-2 is associated with lymph node metastasis in gastric cancer. J Gastroenterol. 2012;47:37-48 pubmed publisher
western blot; human	Bukurova I, Nikitina S, Khankin S, Krasnov G, Lisitsin N, Karpov V, et al. [Identification of protein markers for serum diagnosis of cancer based on microRNA expression profiling]. Mol Biol (Mosk). 2011;45:376-81 pubmed
immunocytochemistry; human immunohistochemistry; human	Wehkamp J, Chu H, Shen B, Feathers R, Kays R, Lee S, et al. Paneth cell antimicrobial peptides: topographical distribution and quantification in human gastrointestinal tissues. FEBS Lett. 2006;580:5344-50 pubmed
immunohistochemistry; human western blot; human	Wehkamp J, Salzman N, Porter E, Nuding S, Weichenthal M, Petras R, et al. Reduced Paneth cell alpha-defensins in ileal Crohn's disease. Proc Natl Acad Sci U S A. 2005;102:18129-34 pubmed
immunohistochemistry - paraffin section; human immunohistochemistry; human ELISA; human western blot; human	Shen B, Porter E, Reynoso E, Shen C, Ghosh D, Connor J, et al. Human defensin 5 expression in intestinal metaplasia of the upper gastrointestinal tract. J Clin Pathol. 2005;58:687-94 pubmed
	Balasubramanian I, Bandyopadhyay S, Flores J, Bianchi Smak J, Lin X, Liu H, et al. Infection and inflammation stimulate expansion of a CD74+ Paneth cell subset to regulate disease progression. EMBO J. 2023;42:e113975 pubmed publisher
	Che Y, Choi I, Song C, Park C, Lim S, Kim J, et al. Peripheral Neuron-Organoid Interaction Induces Colonic Epithelial Differentiation via Non-Synaptic Substance P Secretion. Int J Stem Cells. 2023;16:269-280 pubmed publisher
	McCauley H, Riedman A, Enriquez J, Zhang X, Watanabe Chailland M, Sanchez J, et al. Enteroendocrine Cells Protect the Stem Cell Niche by Regulating Crypt Metabolism in Response to Nutrients. Cell Mol Gastroenterol Hepatol. 2023;15:1293-1310 pubmed publisher
	Liu T, Kern J, Jain U, Sonnek N, Xiong S, Simpson K, et al. Western diet induces Paneth cell defects through microbiome alterations and farnesoid X receptor and type I interferon activation. Cell Host Microbe. 2021;29:988-1001.e6 pubmed publisher
	Schilling B, Schusterman M, Kim D, Repko A, Klett K, Christ G, et al. Adipose-derived stem cells delay muscle atrophy after peripheral nerve injury in the rodent model. Muscle Nerve. 2019;59:603-610 pubmed publisher
	Jabari S, Schrödl F, Kaser Eichberger A, Kofler B, Brehmer A. Alarin in different human intestinal epithelial cell types. Histochem Cell Biol. 2019;151:513-520 pubmed publisher
	Cerrillo E, Moret I, Iborra M, Ramos D, Buso E, Tortosa L, et al. Alpha-defensins (?-Defs) in Crohn's disease: Decrease of ileal ?-Def 5 via permanent methylation and increase in plasma ?-Def 1-3 concentrations offering biomarker utility. Clin Exp Immunol. 2017;: pubmed publisher
	Liu T, Naito T, Liu Z, VanDussen K, Haritunians T, Li D, et al. LRRK2 but not ATG16L1 is associated with Paneth cell defect in Japanese Crohn's disease patients. JCI Insight. 2017;2:e91917 pubmed publisher
	Liu T, Gurram B, Baldridge M, Head R, Lam V, Luo C, et al. Paneth cell defects in Crohn's disease patients promote dysbiosis. JCI Insight. 2016;1:e86907 pubmed publisher
	Scheede Bergdahl C, Bergdahl A, Schjerling P, Qvortrup K, Koskinen S, Dela F. Exercise-induced regulation of matrix metalloproteinases in the skeletal muscle of subjects with type 2 diabetes. Diab Vasc Dis Res. 2014;11:324-34 pubmed publisher
	Xu H, Zhang Y, Sun H, Chen S, Wang F. Effects of acupuncture at GV20 and ST36 on the expression of matrix metalloproteinase 2, aquaporin 4, and aquaporin 9 in rats subjected to cerebral ischemia/reperfusion injury. PLoS ONE. 2014;9:e97488 pubmed publisher
	Kim H, Kang U, Lee H, Jung J, Lee S, Yu M, et al. Profiling of differentially expressed proteins in stage IV colorectal cancers with good and poor outcomes. J Proteomics. 2012;75:2983-97 pubmed publisher
	Rork T, Hadzimichalis N, Kappil M, Merrill G. Acetaminophen attenuates peroxynitrite-activated matrix metalloproteinase-2-mediated troponin I cleavage in the isolated guinea pig myocardium. J Mol Cell Cardiol. 2006;40:553-61 pubmed

product information

master code :

NB110-60002

SKU :

NB110-60002

product name :

Defensin alpha 5 Antibody (8C8) - BSA Free

unit size :

0.1 ml (also 0.025 ml)

description :

The Defensin alpha 5 Antibody (8C8) - BSA Free from Novus is a mouse monoclonal antibody to Defensin alpha 5. This antibody reacts with human. The Defensin alpha 5 Antibody (8C8) - BSA Free has been validated for the following applications: Cytometric Bead Assay Standard,ELISA,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunocytochemistry/ Immunofluorescence,IF/IHC,Immunohistochemistry-Frozen,Flow Cytometry,Dot Blot.

target :

Defensin alpha 5

category :

Primary Antibodies

buffer :

Tris-Glycine and 0.15M NaCl

clonality :

Monoclonal

clone :

8C8

concentration :

2.35 mg/ml

conjugate :

Unconjugated

host :

Mouse

immunogen :

Full-length human Defensin alpha 5 [Swiss-Prot# Q01523]. The propeptide is the full-length protein. In the mature form, it is cleaved at residue 63 (alanine).

isotype :

IgG2b

purity :

Protein G purified

species :

Human

specificity :

This is specific for HD5

theoretical molecular weight :

10 kDa

gene symbol :

DEFA5

accessionNumbers :

Q01523

applications :

ELISA,Western Blot,Immunocytochemistry/ Immunofluorescence,Cytometric Bead Assay Standard,IF/IHC,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Flow Cytometry,Immunohistochemistry,Dot Blot

USD :

409 USD

alt names :

DEF5defensin, alpha 5, preproprotein, defensin 5, Defensin, alpha 5, defensin, alpha 5, Paneth cell-specific, defensin-5, HD-5, MGC129728

storage :

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

more info or order :

Novus Biologicals product webpage