product summary
request information :
company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
Rabbit Polyclonal IRE1 alpha Antibody
catalog :
NB110-59971H
quantity :
0.1 ml
price :
349.00 USD
clonality :
polyclonal
host :
rabbit
conjugate :
HRP
reactivity :
human, mouse
application :
western blot
more info or order :
Novus Biologicals product webpage
product information
Catalog Number :
NB110-59971H
Product Name :
Rabbit Polyclonal IRE1 alpha Antibody
List Price :
349.00 USD
Product Type :
Primary Antibodies
Package Size :
0.1 ml
AltNames :
EC 2.7.11, endoplasmic reticulum to nucleus signaling 1, Endoplasmic reticulum-to-nucleus signaling 1, ER to nucleus signalling 1, FLJ30999, hIRE1p, inositol-requiring 1, Inositol-requiring protein 1, IRE 1a, IRE1a, Ire1-alpha, ire1-alpha, IRE1MGC163279, IRE1P, MGC163277, protein kinase/endoribonuclease, serine/threonine-protein kinase/endoribonuclease IRE1
Background :
IRE1 acts as the sensor of unfolded proteins in the ER that initiates transmittance of the unfolded protein signal from the ER to the nucleus by splicing XBP1 mRNA converting it into a potent unfolded-protein response transcriptional activator. It is a transmembrane protein that has both serine-threonine kinase and endoribonuclease activities. Null mutants are viable, but IRE1 is essential for viability under stress conditions that cause unfolded proteins to accumulate in the ER.
Buffer :
PBS
Clonality :
Polyclonal
Conjugate :
HRP
Application Summary :
Western Blot
Host :
Rabbit
Immunogen :
A synthetic peptide within the human IRE1 alpha protein (within residues 200-300). [Swiss-Prot #O75460]
Localization :
Endoplasmic reticulum
Preservative :
No Preservative
Purity :
Immunogen affinity purified
CrossReactivity :
Human and mouse.
Storage :
Store at 4C in the dark.
Swissprot Human :
O75460
TMW :
110 kDa
Uses :
This IRE1 alpha antibody is useful for Western blot, where a band can be seen at ~110 kDa.
Research Area :
Apoptosis, Cell Biology, Diabetes Research, Hypoxia, Lipid and Metabolism, Neuroscience, Signal Transduction, Unfolded Protein Response
more info or order :
Novus Biologicals product webpage
company information
Novus Biologicals
8100 Southpark Way, A-8
Littleton, CO 80120
novus@novusbio.com
www.novusbio.com
3037301950
headquarters: USA
The mission of Novus Biologicals, LLC is to accelerate scientific discovery by developing and marketing unique products in the forefront of science. Novus Biologicals was organized to provide the biological research community with a mechanism for commercializing unique biological materials. We also focus on continually monitoring scientific trends and supply materials to serve these trends. By making these products widely available to institutional and commercial researchers, Novus Biologicals plays an important role in furthering biological research. All of Novus Biologicals products are supplied with detailed technical information and ongoing support. By serving niche and emerging markets, Novus Biologicals has become specialists in markets and has formed and will continue to form ongoing partnerships with our customers.