UCH-L1/PGP9.5 Antibody | Novus Biologicals NB110-58872 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

UCH-L1/PGP9.5 Antibody

catalog :

NB110-58872

quantity :

0.1 ml (also 0.025 ml)

price :

409 USD

clonality :

polyclonal

host :

chicken

conjugate :

nonconjugated

reactivity :

human, mouse, rat, bovine

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Novus Biologicals product webpage

citations: 15

Reference
Guan Q, Velho R, Jordan A, Pommer S, Radde I, Sehouli J, et al. Nociceptin/Orphanin FQ Opioid Peptide-Receptor Expression in the Endometriosis-Associated Nerve Fibers-Possible Treatment Option?. Cells. 2023;12: pubmed publisher
R xf6 derer P, Belu A, Heidrich L, Siobal M, Isensee J, Prolingheuer J, et al. Emergence of nociceptive functionality and opioid signaling in human induced pluripotent stem cell-derived sensory neurons. Pain. 2023;164:1718-1733 pubmed publisher
Foote A, Lungová V, Thibeault S. Piezo1-expressing vocal fold epithelia modulate remodeling via effects on self-renewal and cytokeratin differentiation. Cell Mol Life Sci. 2022;79:591 pubmed publisher
Yang N, Isensee J, Neel D, Quadros A, Zhang H, Lauzadis J, et al. Anthrax toxins regulate pain signaling and can deliver molecular cargoes into ANTXR2+ DRG sensory neurons. Nat Neurosci. 2022;25:168-179 pubmed publisher
Isensee J, van Cann M, Despang P, Araldi D, Moeller K, Petersen J, et al. Depolarization induces nociceptor sensitization by CaV1.2-mediated PKA-II activation. J Cell Biol. 2021;220: pubmed publisher
Lopez E, Carbajal A, Tian J, Bavencoffe A, Zhu M, Dessauer C, et al. Serotonin enhances depolarizing spontaneous fluctuations, excitability, and ongoing activity in isolated rat DRG neurons via 5-HT4 receptors and cAMP-dependent mechanisms. Neuropharmacology. 2021;184:108408 pubmed publisher
van Cann M, Kuzmenkov A, Isensee J, Andreev Andrievskiy A, Peigneur S, Khusainov G, et al. Scorpion toxin MeuNaTxα-1 sensitizes primary nociceptors by selective modulation of voltage-gated sodium channels. FEBS J. 2020;: pubmed publisher
Garza Carbajal A, Ebersberger A, Thiel A, Ferrari L, Acuna J, Brosig S, et al. Oncostatin M induces hyperalgesic priming and amplifies signaling of cAMP to ERK by RapGEF2 and PKA. J Neurochem. 2021;157:1821-1837 pubmed publisher
Garza Carbajal A, Bavencoffe A, Walters E, Dessauer C. Depolarization-Dependent C-Raf Signaling Promotes Hyperexcitability and Reduces Opioid Sensitivity of Isolated Nociceptors after Spinal Cord Injury. J Neurosci. 2020;40:6522-6535 pubmed publisher
Jetté M, Clary M, Prager J, Finger T. Chemical receptors of the arytenoid: A comparison of human and mouse. Laryngoscope. 2020;130:423-430 pubmed publisher
Boyd N, Walker K, Ayokanmbi A, Gordon E, Whetsel J, Smith C, et al. Chromodomain Helicase DNA-Binding Protein 7 Is Suppressed in the Perinecrotic/Ischemic Microenvironment and Is a Novel Regulator of Glioblastoma Angiogenesis. Stem Cells. 2019;37:453-462 pubmed publisher
Loos C, Moeller K, Fröhlich F, Hucho T, Hasenauer J. A Hierarchical, Data-Driven Approach to Modeling Single-Cell Populations Predicts Latent Causes of Cell-To-Cell Variability. Cell Syst. 2018;6:593-603.e13 pubmed publisher
Isensee J, Kaufholz M, Knape M, Hasenauer J, Hammerich H, Gonczarowska Jorge H, et al. PKA-RII subunit phosphorylation precedes activation by cAMP and regulates activity termination. J Cell Biol. 2018;217:2167-2184 pubmed publisher
Isensee J, Schild C, Schwede F, Hucho T. Crosstalk from cAMP to ERK1/2 emerges during postnatal maturation of nociceptive neurons and is maintained during aging. J Cell Sci. 2017;130:2134-2146 pubmed publisher
Isensee J, Krahé L, Moeller K, Pereira V, Sexton J, Sun X, et al. Synergistic regulation of serotonin and opioid signaling contributes to pain insensitivity in Nav1.7 knockout mice. Sci Signal. 2017;10: pubmed publisher

product information

master code :

NB110-58872

SKU :

NB110-58872

product name :

UCH-L1/PGP9.5 Antibody

unit size :

0.1 ml (also 0.025 ml)

description :

The UCH-L1/PGP9.5 Antibody from Novus is a chicken polyclonal antibody to UCH-L1/PGP9.5. This antibody reacts with bovine,equine,human,mouse,porcine,rat. The UCH-L1/PGP9.5 Antibody has been validated for the following applications: Immunohistochemistry-Frozen,Immunocytochemistry/ Immunofluorescence,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry.

target :

UCH-L1/PGP9.5

category :

Primary Antibodies

buffer :

Supplied as concentrated total IgY preparation from egg yolk. Exact concentration of target specific IgY is not quantifiable as the preparation contains both immune IgY specific for the target and also irrelevant, non-immune IgY.

clonality :

Polyclonal

conjugate :

Unconjugated

host :

Chicken

immunogen :

Recombinant full length human UCHL1 purified from E. coli. [UniProt# P09936]

isotype :

IgY

purity :

IgY purified

species :

Bovine,Equine,Human,Mouse,Porcine,Rat

theoretical molecular weight :

24 kDa

gene symbol :

UCHL1

accessionNumbers :

P09936

applications :

Immunocytochemistry/ Immunofluorescence,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunohistochemistry

USD :

409 USD

alt names :

EC 3.4.19.12, EC 6.-, Neuron cytoplasmic protein 9.5, PARK5, PGP 9.5, PGP9.5, PGP9.5Uch-L1, PGP95, ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase), ubiquitin carboxyl-terminal hydrolase isozyme L1, ubiquitin C-terminal hydrolase, Ubiquitin thioesterase L1, UCHL1, UCH-L1

storage :

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

more info or order :

Novus Biologicals product webpage