product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
Enolase 2/Neuron-specific Enolase Antibody
catalog :
NB110-58870
quantity :
0.1 ml (also 0.025 ml)
price :
409 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry
more info or order :
citations: 18
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; human; 1:300; loading ...; fig 3e
Powers R, Daza R, Koehler A, Courchet J, Calabrese B, Hevner R, et al. Growth cone macropinocytosis of neurotrophin receptor and neuritogenesis are regulated by neuron navigator 1. Mol Biol Cell. 2022;33:ar64 pubmed publisher
  • immunohistochemistry; human; fig 3c
Jung Y, Cackowski F, Yumoto K, Decker A, Wang J, Kim J, et al. CXCL12γ Promotes Metastatic Castration-Resistant Prostate Cancer by Inducing Cancer Stem Cell and Neuroendocrine Phenotypes. Cancer Res. 2018;78:2026-2039 pubmed publisher
Niture S, Tricoli L, Qi Q, Gadi S, Hayes K, Kumar D. MicroRNA-99b-5p targets mTOR/AR axis, induces autophagy and inhibits prostate cancer cell proliferation. Tumour Biol. 2022;44:107-127 pubmed publisher
Traub S, Heilker R. hiPS Cell-Derived Neurons for High-Throughput Screening. Methods Mol Biol. 2019;1994:243-263 pubmed publisher
Modarai S, Gupta A, Opdenaker L, Kowash R, Masters G, Viswanathan V, et al. The anti-cancer effect of retinoic acid signaling in CRC occurs via decreased growth of ALDH+ colon cancer stem cells and increased differentiation of stem cells. Oncotarget. 2018;9:34658-34669 pubmed publisher
Okazaki M, Fushida S, Tsukada T, Kinoshita J, Oyama K, Miyashita T, et al. The effect of HIF-1? and PKM1 expression on acquisition of chemoresistance. Cancer Manag Res. 2018;10:1865-1874 pubmed publisher
Shanmugasundaram K, Nayak B, Friedrichs W, Kaushik D, Rodriguez R, Block K. NOX4 functions as a mitochondrial energetic sensor coupling cancer metabolic reprogramming to drug resistance. Nat Commun. 2017;8:997 pubmed publisher
Minami K, Taniguchi K, Sugito N, Kuranaga Y, Inamoto T, Takahara K, et al. MiR-145 negatively regulates Warburg effect by silencing KLF4 and PTBP1 in bladder cancer cells. Oncotarget. 2017;8:33064-33077 pubmed publisher
Takai T, Yoshikawa Y, Inamoto T, Minami K, Taniguchi K, Sugito N, et al. A Novel Combination RNAi toward Warburg Effect by Replacement with miR-145 and Silencing of PTBP1 Induces Apoptotic Cell Death in Bladder Cancer Cells. Int J Mol Sci. 2017;18: pubmed publisher
Sugiyama T, Taniguchi K, Matsuhashi N, Tajirika T, Futamura M, Takai T, et al. MiR-133b inhibits growth of human gastric cancer cells by silencing pyruvate kinase muscle-splicer polypyrimidine tract-binding protein 1. Cancer Sci. 2016;107:1767-1775 pubmed publisher
Casson R, Wood J, Han G, Kittipassorn T, Peet D, Chidlow G. M-Type Pyruvate Kinase Isoforms and Lactate Dehydrogenase A in the Mammalian Retina: Metabolic Implications. Invest Ophthalmol Vis Sci. 2016;57:66-80 pubmed publisher
Taniguchi K, Sugito N, Kumazaki M, Shinohara H, Yamada N, Matsuhashi N, et al. Positive feedback of DDX6/c-Myc/PTB1 regulated by miR-124 contributes to maintenance of the Warburg effect in colon cancer cells. Biochim Biophys Acta. 2015;1852:1971-80 pubmed publisher
Taniguchi K, Sugito N, Kumazaki M, Shinohara H, Yamada N, Nakagawa Y, et al. MicroRNA-124 inhibits cancer cell growth through PTB1/PKM1/PKM2 feedback cascade in colorectal cancer. Cancer Lett. 2015;363:17-27 pubmed publisher
Taniguchi K, Ito Y, Sugito N, Kumazaki M, Shinohara H, Yamada N, et al. Organ-specific PTB1-associated microRNAs determine expression of pyruvate kinase isoforms. Sci Rep. 2015;5:8647 pubmed publisher
Shinohara H, Taniguchi K, Kumazaki M, Yamada N, Ito Y, Otsuki Y, et al. Anti-cancer fatty-acid derivative induces autophagic cell death through modulation of PKM isoform expression profile mediated by bcr-abl in chronic myeloid leukemia. Cancer Lett. 2015;360:28-38 pubmed publisher
Fong M, Zhou W, Liu L, Alontaga A, Chandra M, Ashby J, et al. Breast-cancer-secreted miR-122 reprograms glucose metabolism in premetastatic niche to promote metastasis. Nat Cell Biol. 2015;17:183-94 pubmed publisher
Palsson McDermott E, Curtis A, Goel G, Lauterbach M, Sheedy F, Gleeson L, et al. Pyruvate kinase M2 regulates Hif-1? activity and IL-1? induction and is a critical determinant of the warburg effect in LPS-activated macrophages. Cell Metab. 2015;21:65-80 pubmed publisher
Bruns D, Brown R, Stenmark K, Buttrick P, Walker L. Mitochondrial integrity in a neonatal bovine model of right ventricular dysfunction. Am J Physiol Lung Cell Mol Physiol. 2015;308:L158-67 pubmed publisher
product information
master code :
NB110-58870
SKU :
NB110-58870
product name :
Enolase 2/Neuron-specific Enolase Antibody
unit size :
0.1 ml (also 0.025 ml)
description :
The Enolase 2/Neuron-specific Enolase Antibody from Novus is a rabbit polyclonal antibody to Enolase 2/Neuron-specific Enolase. This antibody reacts with human,mouse,rat. The Enolase 2/Neuron-specific Enolase Antibody has been validated for the following applications: Western Blot,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry,Simple Western,Knockdown Validated.
target :
Enolase 2/Neuron-specific Enolase
category :
Primary Antibodies
buffer :
Supplied as serum
clonality :
Polyclonal
conjugate :
Unconjugated
host :
Rabbit
immunogen :
Recombinant full length human NSE purified from E. coli. [UniProt# P09104]
isotype :
IgG
purity :
Unpurified
species :
Human,Mouse,Rat
theoretical molecular weight :
47 kDa
gene symbol :
ENO2
accessionNumbers :
P09104
applications :
Western Blot,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry,Simple Western,Knockdown Validated
USD :
409 USD
alt names :
2-phospho-D-glycerate hydrolyase, 2-phospho-D-glycerate hydro-lyase, EC 4.2.1.11, Enolase 2, enolase 2 (gamma, neuronal), gamma-enolase, Neural enolase, neuron specific gamma enolase, neurone-specific enolase, Neuron-specific enolase, NSE
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.