product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
Nox4 Antibody - BSA Free
catalog :
NB110-58851
quantity :
0.1 ml (also 0.025 ml)
price :
399 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
AF700
clone name :
6C5cc
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 27
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - frozen section; mouse; 1:100; loading ...; fig 1c
  • western blot; mouse; 1:1000; loading ...; fig 1b
Chen C, Wang S, Yu L, Mueller J, Fortunato F, Rausch V, et al. H2O2-mediated autophagy during ethanol metabolism. Redox Biol. 2021;46:102081 pubmed publisher
Lee G, Shin Y, Kim J, Shim D, Lee H, Zhao L, et al. The Combination of Curcumae Radix and Syzygium Aromaticum Extracts Mitigates Benign Prostatic Hyperplasia through Anti-Proliferative and Anti-Inflammatory Effects. World J Mens Health. 2024;: pubmed publisher
Lee W, Probst S, Scharner B, Deba T, Dahdouh F, Th xe9 venod F. Distinct concentration-dependent oxidative stress profiles by cadmium in a rat kidney proximal tubule cell line. Arch Toxicol. 2024;98:1043-1059 pubmed publisher
Kang L, Piao M, Liu N, Gu W, Feng C. Sevoflurane Exposure Induces Neuronal Cell Ferroptosis Initiated by Increase of Intracellular Hydrogen Peroxide in the Developing Brain via ER Stress ATF3 Activation. Mol Neurobiol. 2024;61:2313-2335 pubmed publisher
Arias Cavieres A, Garcia A. A Consequence of Immature Breathing induces Persistent Changes in Hippocampal Synaptic Plasticity and Behavior: A Role of Pro-Oxidant State and NMDA Receptor Imbalance. bioRxiv. 2023;: pubmed publisher
Hwang S, Kim S, Yoo K, Chung M, Lee J, Son K. Exogenous 8-hydroxydeoxyguanosine attenuates doxorubicin-induced cardiotoxicity by decreasing pyroptosis in H9c2 cardiomyocytes. BMC Mol Cell Biol. 2022;23:55 pubmed publisher
Mellone M, Piotrowska K, Venturi G, James L, Bzura A, Lopez M, et al. ATM Regulates Differentiation of Myofibroblastic Cancer-Associated Fibroblasts and Can Be Targeted to Overcome Immunotherapy Resistance. Cancer Res. 2022;82:4571-4585 pubmed publisher
Tang P, Sheng J, Peng X, Zhang R, Xu T, Hu J, et al. Targeting NOX4 disrupts the resistance of papillary thyroid carcinoma to chemotherapeutic drugs and lenvatinib. Cell Death Discov. 2022;8:177 pubmed publisher
Wang N, Peng Y, Su X, Prabhakar N, Nanduri J. Histone Deacetylase 5 Is an Early Epigenetic Regulator of Intermittent Hypoxia Induced Sympathetic Nerve Activation and Blood Pressure. Front Physiol. 2021;12:688322 pubmed publisher
Ke G, Chen X, Liao R, Xu L, Zhang L, Zhang H, et al. Receptor activator of NF-κB mediates podocyte injury in diabetic nephropathy. Kidney Int. 2021;100:377-390 pubmed publisher
Vandenberg G, Dawson N, Head A, Scott G, Scott A. Astrocyte-mediated disruption of ROS homeostasis in Fragile X mouse model. Neurochem Int. 2021;146:105036 pubmed publisher
García Arroyo F, Tapia E, Muñoz Jimenez I, Gonzaga Sánchez G, Arellano Buendía A, Osorio Alonso H, et al. Fluid Intake Restriction Concomitant to Sweetened Beverages Hydration Induce Kidney Damage. Oxid Med Cell Longev. 2020;2020:8850266 pubmed publisher
Lee H, Kim H, Hoang T, Yang S, Kim H, Chae H. The correlation of IRE1α oxidation with Nox4 activation in aging-associated vascular dysfunction. Redox Biol. 2020;37:101727 pubmed publisher
Wang N, Shi X, Khan S, Wang B, Semenza G, Prabhakar N, et al. Hypoxia-inducible factor-1 mediates pancreatic β-cell dysfunction by intermittent hypoxia. Am J Physiol Cell Physiol. 2020;319:C922-C932 pubmed publisher
Schader T, Löwe O, Reschke C, Malacarne P, Hahner F, Müller N, et al. Oxidation of HDAC4 by Nox4-derived H2O2 maintains tube formation by endothelial cells. Redox Biol. 2020;36:101669 pubmed publisher
Karageorgiadi D, Tsilimigras D, Selemenakis P, Vlachou V, de Lastic A, Rodi M, et al. Conditioning attenuates kidney and heart injury in rats following transient suprarenal occlusion of the abdominal aorta. Sci Rep. 2020;10:5040 pubmed publisher
García Arroyo F, Gonzaga G, Muñoz Jimenez I, Osorio Alonso H, Iroz A, Vecchio M, et al. Antioxidant supplements as a novel mean for blocking recurrent heat stress-induced kidney damage following rehydration with fructose-containing beverages. Free Radic Biol Med. 2019;141:182-191 pubmed publisher
Diebold B, Wilder S, De Deken X, Meitzler J, Doroshow J, McCoy J, et al. Guidelines for the Detection of NADPH Oxidases by Immunoblot and RT-qPCR. Methods Mol Biol. 2019;1982:191-229 pubmed publisher
Stuart J, Fonseca J, Moradi F, Cunningham C, Seliman B, Worsfold C, et al. How Supraphysiological Oxygen Levels in Standard Cell Culture Affect Oxygen-Consuming Reactions. Oxid Med Cell Longev. 2018;2018:8238459 pubmed publisher
Varga Z, Pipicz M, Baán J, Baranyai T, Koncsos G, Leszek P, et al. Alternative Splicing of NOX4 in the Failing Human Heart. Front Physiol. 2017;8:935 pubmed publisher
Bidwell P, Liu G, Nagarajan N, Lam C, Haghighi K, Gardner G, et al. HAX-1 regulates SERCA2a oxidation and degradation. J Mol Cell Cardiol. 2018;114:220-233 pubmed publisher
Feng C, Zhang Y, Yang M, Lan M, Liu H, Huang B, et al. Oxygen-Sensing Nox4 Generates Genotoxic ROS to Induce Premature Senescence of Nucleus Pulposus Cells through MAPK and NF-?B Pathways. Oxid Med Cell Longev. 2017;2017:7426458 pubmed publisher
Goitre L, DiStefano P, Moglia A, Nobiletti N, Baldini E, Trabalzini L, et al. Up-regulation of NADPH oxidase-mediated redox signaling contributes to the loss of barrier function in KRIT1 deficient endothelium. Sci Rep. 2017;7:8296 pubmed publisher
Shi Y, Zhang X, Chen C, Tang M, Wang Z, Liang X, et al. Schisantherin A attenuates ischemia/reperfusion-induced neuronal injury in rats via regulation of TLR4 and C5aR1 signaling pathways. Brain Behav Immun. 2017;66:244-256 pubmed publisher
Fierro Fernández M, Busnadiego Ã, Sandoval P, Espinosa Díez C, Blanco Ruiz E, Rodríguez M, et al. miR-9-5p suppresses pro-fibrogenic transformation of fibroblasts and prevents organ fibrosis by targeting NOX4 and TGFBR2. EMBO Rep. 2015;16:1358-77 pubmed publisher
Stanicka J, Russell E, Woolley J, Cotter T. NADPH oxidase-generated hydrogen peroxide induces DNA damage in mutant FLT3-expressing leukemia cells. J Biol Chem. 2015;290:9348-61 pubmed publisher
Padron A, Neto R, Pantaleão T, de Souza Dos Santos M, Araujo R, de Andrade B, et al. Administration of 3,5-diiodothyronine (3,5-T2) causes central hypothyroidism and stimulates thyroid-sensitive tissues. J Endocrinol. 2014;221:415-27 pubmed publisher
product information
master code :
NB110-58851
SKU :
NB110-58851
product name :
Nox4 Antibody - BSA Free
unit size :
0.1 ml (also 0.025 ml)
description :
The Nox4 Antibody - BSA Free from Novus is a rabbit polyclonal antibody to Nox4. This antibody reacts with human,mouse,porcine,primate,rat. The Nox4 Antibody - BSA Free has been validated for the following applications: Western Blot,IF/IHC,Immunoprecipitation,Immunohistochemistry-Paraffin,Immunocytochemistry/ Immunofluorescence,Simple Western,Flow Cytometry,Immunohistochemistry,Flow (Intracellular).
target :
Nox4
category :
Primary Antibodies
buffer :
PBS
clonality :
Polyclonal
concentration :
1.0 mg/ml
conjugate :
Unconjugated
host :
Rabbit
immunogen :
A synthetic peptide made to a C-terminal region (within residues 500-578) of the human NOX4 protein sequence. [Swiss-Prot# Q9NPH5].
isotype :
IgG
purity :
Immunogen affinity purified
species :
Human,Mouse,Porcine,Primate,Rat
gene symbol :
NOX4
Antibody validation :
Biological Validation
applications :
IF/IHC,Immunoprecipitation,Western Blot,Immunohistochemistry-Paraffin,Immunocytochemistry/ Immunofluorescence,Simple Western,Flow Cytometry,Immunohistochemistry,Flow (Intracellular)
USD :
399 USD
alt names :
EC 1.6.3, Kidney oxidase-1, Kidney superoxide-producing NADPH oxidase, KOX, KOX-1Renal NAD(P)H-oxidase, NADPH oxidase 4, RENOXEC 1.6.3.-
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.