product summary
request information :
company name :
Novus Biologicals
product type :
antibody
product name :
Mouse Monoclonal CD13 Antibody
catalog :
NB110-58720G
quantity :
0.05 mg
price :
429.00 USD
clonality :
monoclonal
host :
mouse
reactivity :
human
application :
immunoprecipitation, immunohistochemistry, flow cytometry
more info or order :
Novus Biologicals product webpage
product information
Catalog Number :
NB110-58720G
Product Name :
Mouse Monoclonal CD13 Antibody
List Price :
429.00 USD
Product Type :
Primary Antibodies
Package Size :
0.05 mg
AltNames :
alanyl (membrane) aminopeptidase, Alanyl aminopeptidase, AP-M, Aminopeptidase M, aminopeptidase N, AP-N, CD13APN, CD13 antigen, EC 3.4.11, EC 3.4.11.2, gp150, GP150, LAP1, Microsomal aminopeptidase, Myeloid plasma membrane glycoprotein CD13, P150, p150, PEPNhAPN
Background :
Human CD13 is expressed on the majority of peripheral blood monocytes and granulocytes. It is also expressed by the majority of acute myeloid leukemias, chronic myeloid leukemias in myeloid blast crisis, a smaller percentage of lymphoid leukemias and myeloid cell lines. CD13 is also found in several types of non hematopoietic cells such as fibroblasts and endothelial cells and in a soluble form in blood plasma. CD13 is not expressed on B cells, T cells, platelets or erythrocytes. In the mouse, CD13 is a non-covalently linked homodimer of approximately 150kD subunits expressed by a variety of cells including monocytes, macrophages, dendritic cell and veiled cells. CD13 plays a role in biologically active peptide metabolism, in the control of growth and differentiation, in phagocytosis and in bactericidal/tumoricidal activities. CD13 also serves as a receptor for human coronaviruses (HCV).
Buffer :
50mM sodium borate
Clonality :
Monoclonal
Clone :
WM15
Concentration :
1.0 mg/ml
Conjugate :
DyLight 488
Application Summary :
Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Frozen, Immunoprecipitation
Host :
Mouse
Immunogen :
Human AML cells (NM_001150.2).
Isotype :
IgG1
Preservative :
No Preservative
Purity :
Protein A purified
CrossReactivity :
Human and non-human primates.
Specificity :
The WM15 recognises the human CD13 cell surface glycoprotein, a 150kD molecule expressed on granulocytes, endothelial cells, epithelial cells and myeloid progenitors.
Storage :
Store at 4C in the dark.
Swissprot Human :
P15144
Uses :
Functional: The antibody WM15 inhibits infection of cells by human coronavirus and inhibits aminopeptidase N activity of the CD13 molecule immunoprecipitates. Purity is > 95% (by SDS-PAGE).
Research Area :
Angiogenesis, Cellular Markers, Hematopoietic Stem Cell Markers, Immunology, Mesenchymal Stem Cell Markers, Stem Cell Markers
more info or order :
Novus Biologicals product webpage
company information
Novus Biologicals
8100 Southpark Way, A-8
Littleton, CO 80120
novus@novusbio.com
www.novusbio.com
3037301950
headquarters: usa
The mission of Novus Biologicals, LLC is to accelerate scientific discovery by developing and marketing unique products in the forefront of science. Novus Biologicals was organized to provide the biological research community with a mechanism for commercializing unique biological materials. We also focus on continually monitoring scientific trends and supply materials to serve these trends. By making these products widely available to institutional and commercial researchers, Novus Biologicals plays an important role in furthering biological research. All of Novus Biologicals products are supplied with detailed technical information and ongoing support. By serving niche and emerging markets, Novus Biologicals has become specialists in markets and has formed and will continue to form ongoing partnerships with our customers.