product summary
request information :
company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
Rabbit Polyclonal FE65 Antibody
catalog :
NB110-58360R
quantity :
0.1 ml
price :
319.00 USD
clonality :
polyclonal
host :
rabbit
conjugate :
DyLight 550
reactivity :
human, mouse, rat
application :
western blot, immunoprecipitation
more info or order :
Novus Biologicals product webpage
product information
Catalog Number :
NB110-58360R
Product Name :
Rabbit Polyclonal FE65 Antibody
List Price :
319.00 USD
Product Type :
Primary Antibodies
Package Size :
0.1 ml
AltNames :
Fe65, FE65amyloid beta A4 precursor protein-binding family B member 1, MGC:9072, Protein Fe65, RIR, stat-like protein, adaptor protein FE65a2, amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65), amyloid beta A4 precursor protein-binding, family B, member 1
Background :
FE65 is a signaling adaptor of APP protein. The FE65/APP complex was shown to translocate into the cell nucleus and regulate gene expression. Genetic studies in mice validated FE65-APP interaction and molecular studies provided evidence on the role of the complex in abnormal signaling detected in brains of Alzheimer Disease patients.
Buffer :
50mM sodium borate
Clonality :
Polyclonal
Conjugate :
DyLight 550
Application Summary :
Western Blot, Immunoprecipitation
Host :
Rabbit
Immunogen :
Recombinant rat FE65, expressed in bacteria. [Swiss-Prot# P46933]
Localization :
Cytoplasmic
Preservative :
No Preservative
Purity :
Immunogen affinity purified
CrossReactivity :
Rat, human, and mouse.
Storage :
Store at 4C in the dark.
TMW :
100 kDa
Uses :
This FE65 antibody is useful in Western blot and Immunoprecipitation. In Western blot a band is seen at ~100 kDa versus the predicted molecular weight of 77 kDa, which corresponds to earlier findings in literature (PMID: 9685356).
Research Area :
Alzheimers Research, Cell Cycle and Replication, Neurodegeneration, Neuroscience, Signal Transduction
more info or order :
Novus Biologicals product webpage
company information
Novus Biologicals
8100 Southpark Way, A-8
Littleton, CO 80120
novus@novusbio.com
www.novusbio.com
3037301950
headquarters: USA
The mission of Novus Biologicals, LLC is to accelerate scientific discovery by developing and marketing unique products in the forefront of science. Novus Biologicals was organized to provide the biological research community with a mechanism for commercializing unique biological materials. We also focus on continually monitoring scientific trends and supply materials to serve these trends. By making these products widely available to institutional and commercial researchers, Novus Biologicals plays an important role in furthering biological research. All of Novus Biologicals products are supplied with detailed technical information and ongoing support. By serving niche and emerging markets, Novus Biologicals has become specialists in markets and has formed and will continue to form ongoing partnerships with our customers.