product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
TAZ/WWTR1 Antibody - BSA Free
catalog :
NB110-58359
quantity :
0.1 ml (also 0.025 ml)
price :
419 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, chromatin immunoprecipitation, immunohistochemistry - paraffin section, proximity ligation assay
more info or order :
Novus Biologicals product webpage
citations: 23
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:1000; fig 2a
Van Sciver N, Ohashi M, Pauly N, Bristol J, Nelson S, JOHANNSEN E, et al. Hippo signaling effectors YAP and TAZ induce Epstein-Barr Virus (EBV) lytic reactivation through TEADs in epithelial cells. PLoS Pathog. 2021;17:e1009783 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:200; loading ...; fig 1f
Kegelman C, Coulombe J, Jordan K, Horan D, Qin L, Robling A, et al. YAP and TAZ Mediate Osteocyte Perilacunar/Canalicular Remodeling. J Bone Miner Res. 2020;35:196-210 pubmed publisher
Leonard B, Park S, Kim S, Young L, Jalilian I, Cosert K, et al. Mice Deficient in TAZ (Wwtr1) Demonstrate Clinical Features of Late-Onset Fuchs' Endothelial Corneal Dystrophy. Invest Ophthalmol Vis Sci. 2023;64:22 pubmed publisher
Wu M, Matar D, Yu Z, Chen Z, Knoedler S, Ng B, et al. Continuous NPWT Regulates Fibrosis in Murine Diabetic Wound Healing. Pharmaceutics. 2022;14: pubmed publisher
Das A, Adhikary S, Chowdhury A, Barui A. Leveraging Substrate Stiffness to Promote Stem Cell Asymmetric Division via Mechanotransduction-Polarity Protein Axis and Its Bayesian Regression Analysis. Rejuvenation Res. 2022;25:59-69 pubmed publisher
Hwang J, Kim K, Oh H, Yoo G, Jeong M, Lee H, et al. TAZ links exercise to mitochondrial biogenesis via mitochondrial transcription factor A. Nat Commun. 2022;13:653 pubmed publisher
Luu A, Yao Z, Ramachandran S, Azzopardi S, Miles L, Schneider W, et al. A CRISPR Activation Screen Identifies an Atypical Rho GTPase That Enhances Zika Viral Entry. Viruses. 2021;13: pubmed publisher
Yemanyi F, Raghunathan V. Lysophosphatidic Acid and IL-6 Trans-signaling Interact via YAP/TAZ and STAT3 Signaling Pathways in Human Trabecular Meshwork Cells. Invest Ophthalmol Vis Sci. 2020;61:29 pubmed publisher
Kegelman C, Nijsure M, Moharrer Y, Pearson H, Dawahare J, Jordan K, et al. YAP and TAZ Promote Periosteal Osteoblast Precursor Expansion and Differentiation for Fracture Repair. J Bone Miner Res. 2021;36:143-157 pubmed publisher
Yemanyi F, Vranka J, Raghunathan V. Crosslinked Extracellular Matrix Stiffens Human Trabecular Meshwork Cells Via Dysregulating β-catenin and YAP/TAZ Signaling Pathways. Invest Ophthalmol Vis Sci. 2020;61:41 pubmed publisher
Li W, Zhao J, Wang J, Sun L, Xu H, Sun W, et al. ROCK-TAZ signaling axis regulates mechanical tension-induced osteogenic differentiation of rat cranial sagittal suture mesenchymal stem cells. J Cell Physiol. 2020;235:5972-5984 pubmed publisher
Udden S, Kwak Y, Godfrey V, Khan M, Khan S, Loof N, et al. NLRP12 suppresses hepatocellular carcinoma via downregulation of cJun N-terminal kinase activation in the hepatocyte. elife. 2019;8: pubmed publisher
Walker S, Wankell M, Ho V, White R, Deo N, Devine C, et al. Targeting mTOR and Src restricts hepatocellular carcinoma growth in a novel murine liver cancer model. PLoS ONE. 2019;14:e0212860 pubmed publisher
Hwang J, Kim A, Kim K, Il Park J, Oh H, Moon S, et al. TAZ couples Hippo/Wnt signalling and insulin sensitivity through Irs1 expression. Nat Commun. 2019;10:421 pubmed publisher
Yu B, Huo L, Liu Y, Deng P, Szymanski J, Li J, et al. PGC-1α Controls Skeletal Stem Cell Fate and Bone-Fat Balance in Osteoporosis and Skeletal Aging by Inducing TAZ. Cell Stem Cell. 2018;23:193-209.e5 pubmed publisher
Knittelfelder O, Traikov S, Vvedenskaya O, Schuhmann A, Segeletz S, Shevchenko A, et al. Shotgun Lipidomics Combined with Laser Capture Microdissection: A Tool To Analyze Histological Zones in Cryosections of Tissues. Anal Chem. 2018;90:9868-9878 pubmed publisher
Janardhan K, Jensen H, Clayton N, Herbert R. Immunohistochemistry in Investigative and Toxicologic Pathology. Toxicol Pathol. 2018;46:488-510 pubmed publisher
Wu L, Deng Y, Wang J, Zhao C, Wang J, Rao R, et al. Programming of Schwann Cells by Lats1/2-TAZ/YAP Signaling Drives Malignant Peripheral Nerve Sheath Tumorigenesis. Cancer Cell. 2018;33:292-308.e7 pubmed publisher
Stradiot L, Verhulst S, Roosens T, Øie C, Moya I, Halder G, et al. Functionality based method for simultaneous isolation of rodent hepatic sinusoidal cells. Biomaterials. 2017;139:91-101 pubmed publisher
Deng Y, Wu L, Bai S, Zhao C, Wang H, Wang J, et al. A reciprocal regulatory loop between TAZ/YAP and G-protein Gαs regulates Schwann cell proliferation and myelination. Nat Commun. 2017;8:15161 pubmed publisher
Luijten M, Zwart E, Dollé M, de Pooter M, Cox J, White P, et al. Evaluation of the LacZ reporter assay in cryopreserved primary hepatocytes for In vitro genotoxicity testing. Environ Mol Mutagen. 2016;57:643-655 pubmed publisher
Xiang L, Gilkes D, Hu H, Luo W, Bullen J, Liang H, et al. HIF-1α and TAZ serve as reciprocal co-activators in human breast cancer cells. Oncotarget. 2015;6:11768-78 pubmed
Pandey V, Jain S, Rana A, Puri N, Arudra S, Mopidevi B, et al. Dexamethasone promotes hypertension by allele-specific regulation of the human angiotensinogen gene. J Biol Chem. 2015;290:5749-58 pubmed publisher
product information
master code :
NB110-58359
SKU :
NB110-58359
product name :
TAZ/WWTR1 Antibody - BSA Free
unit size :
0.1 ml (also 0.025 ml)
description :
The TAZ/WWTR1 Antibody - BSA Free from Novus is a rabbit polyclonal antibody to TAZ/WWTR1. This antibody reacts with human,mouse,rat. The TAZ/WWTR1 Antibody - BSA Free has been validated for the following applications: Immunohistochemistry,Immunocytochemistry/ Immunofluorescence,Chemotaxis,Immunoprecipitation,Western Blot,Immunohistochemistry-Paraffin,Chromatin Immunoprecipitation,Proximity Ligation Assay,Simple Western,Chromatin Immunoprecipitation (ChIP).
target :
TAZ/WWTR1
category :
Primary Antibodies
buffer :
PBS
clonality :
Polyclonal
concentration :
1.0 mg/ml
conjugate :
Unconjugated
host :
Rabbit
immunogen :
Synthetic peptides made to the human TAZ protein. These peptides were selected for the lack of homology to YAP protein. [UniProt# Q9GZV5]
isotype :
IgG
purity :
Immunogen affinity purified
species :
Human,Mouse,Rat
gene symbol :
WWTR1
accessionNumbers :
Q9GZV5
applications :
Immunohistochemistry,Immunocytochemistry/ Immunofluorescence,Chemotaxis,Immunoprecipitation,Western Blot,Immunohistochemistry-Paraffin,Chromatin Immunoprecipitation,Proximity Ligation Assay,Simple Western,Chromatin Immunoprecipitation (ChIP)
USD :
419 USD
alt names :
FLJ27004, FLJ45718, TAZDKFZp586I1419, transcriptional co-activator with PDZ-binding motif, Transcriptional coactivator with PDZ-binding motif, WW domain containing transcription regulator 1, WW domain-containing transcription regulator protein 1
storage :
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
more info or order :
Novus Biologicals product webpage
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.