product summary
request information :
company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
Mouse Monoclonal Apolipoprotein A5 Antibody
catalog :
NB110-55454H
quantity :
0.1 ml
price :
309.00 USD
clonality :
monoclonal
host :
mouse
conjugate :
HRP
reactivity :
human
application :
western blot, ELISA
more info or order :
Novus Biologicals product webpage
product information
Catalog Number :
NB110-55454H
Product Name :
Mouse Monoclonal Apolipoprotein A5 Antibody
List Price :
309.00 USD
Product Type :
Primary Antibodies
Package Size :
0.1 ml
AltNames :
FLJ97995, MGC126836, RAP3MGC126838, Regeneration-associated protein 3, APOAV, apo-AV, Apo-AV, APOA-V, ApoA-V, Apolipoprotein A5, apolipoprotein A-V
Background :
Apolipoprotein A5 (ApoA5) is fast gaining attention as a key regulator of serum triglyceride concentrations. An ApoA5 mouse knock-out model produced an approximately four fold increase in serum triglycerides, whereas a knock-in model with human ApoA5 produced 50-70% lower concentrations of mouse serum triglycerides. In addition, peroxisome proliferator-activated receptor-4 (PPAR-alpha) agonists, which are used clinically to lower serum triglyceride concentrations, cause increased ApoA5 mRNA expression. Recently, it was demonstrated that ApoA5 is present in human serum detected by polyclonal antibodies against both the NH2 and COOH termini, although at much lower concentration than other apolipoproteins. THIS PRODUCT IS THE PURIFIED VERSION OF NB 400-139.
Buffer :
PBS
Clonality :
Monoclonal
Clone :
1G5G9
Conjugate :
HRP
Application Summary :
Western Blot, ELISA
Host :
Mouse
Immunogen :
Ni-NTA purified full-length recombinant human Apolipoprotein A5 expressed in E. Coli strain BL21 (DE3). [UniProt# Q6Q788]
Isotype :
IgG1 Kappa
Localization :
Secreted
Preservative :
No Preservative
Purity :
Protein G purified
CrossReactivity :
Human
Storage :
Store at 4C in the dark.
Swissprot Human :
Q6Q788
TMW :
41 kDa
Uses :
This Apolipoprotein A5 antibody is useful in ELISA, Immunohistochemistry paraffin embedded sections and Western blot.
Research Area :
Cancer, Cholesterol Metabolism, Lipid and Metabolism, Signal Transduction
more info or order :
Novus Biologicals product webpage
company information
Novus Biologicals
8100 Southpark Way, A-8
Littleton, CO 80120
novus@novusbio.com
www.novusbio.com
3037301950
headquarters: USA
The mission of Novus Biologicals, LLC is to accelerate scientific discovery by developing and marketing unique products in the forefront of science. Novus Biologicals was organized to provide the biological research community with a mechanism for commercializing unique biological materials. We also focus on continually monitoring scientific trends and supply materials to serve these trends. By making these products widely available to institutional and commercial researchers, Novus Biologicals plays an important role in furthering biological research. All of Novus Biologicals products are supplied with detailed technical information and ongoing support. By serving niche and emerging markets, Novus Biologicals has become specialists in markets and has formed and will continue to form ongoing partnerships with our customers.