product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
DRP1 Antibody - BSA Free
catalog :
NB110-55288
quantity :
0.1 ml (also 0.025 ml)
price :
409 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section
more info or order :
citations: 40
Published Application/Species/Sample/DilutionReference
  • western blot; rat; loading ...; fig 4d
Kong Y, Akatsuka S, Motooka Y, Zheng H, Cheng Z, Shiraki Y, et al. BRCA1 haploinsufficiency promotes chromosomal amplification under Fenton reaction-based carcinogenesis through ferroptosis-resistance. Redox Biol. 2022;54:102356 pubmed publisher
Filice M, Gattuso A, Imbrogno S, Mazza R, Amelio D, Caferro A, et al. Functional, structural, and molecular remodelling of the goldfish (Carassius auratus) heart under moderate hypoxia. Fish Physiol Biochem. 2024;50:667-685 pubmed publisher
Mesquita P, Godwin J, Ruple B, Sexton C, McIntosh M, Mueller B, et al. Resistance training diminishes mitochondrial adaptations to subsequent endurance training in healthy untrained men. J Physiol. 2023;601:3825-3846 pubmed publisher
Acosta C, Clemons G, Citadin C, Carr W, Udo M, Tesic V, et al. PRMT7 can prevent neurovascular uncoupling, blood-brain barrier permeability, and mitochondrial dysfunction in repetitive and mild traumatic brain injury. Exp Neurol. 2023;366:114445 pubmed publisher
Mesquita P, Godwin J, Ruple B, Sexton C, McIntosh M, Mueller B, et al. Resistance Training Diminishes Mitochondrial Adaptations to Subsequent Endurance Training. bioRxiv. 2023;: pubmed publisher
Woo J, Seo H, Lee J, Lee I, Jeon K, Kim B, et al. Polypropylene nanoplastic exposure leads to lung inflammation through p38-mediated NF-κB pathway due to mitochondrial damage. Part Fibre Toxicol. 2023;20:2 pubmed publisher
Mesquita P, Osburn S, Godwin J, Roberts M, Kavazis A. Effects of aging and long-term physical activity on mitochondrial physiology and redox state of the cortex and cerebellum of female rats. Physiol Rep. 2022;10:e15542 pubmed publisher
Saito E, Warren C, Hanegan C, Larsen J, du Randt J, Cannon M, et al. A Novel Ketone-Supplemented Diet Improves Recognition Memory and Hippocampal Mitochondrial Efficiency in Healthy Adult Mice. Metabolites. 2022;12: pubmed publisher
Xie J, Zhong F, Guo Z, Li X, Wang J, Gao Z, et al. Hyperinsulinemia impairs the metabolic switch to ketone body utilization in proximal renal tubular epithelial cells under energy crisis via the inhibition of the SIRT3/SMCT1 pathway. Front Endocrinol (Lausanne). 2022;13:960835 pubmed publisher
Kshirsagar S, Alvir R, Pradeepkiran J, Hindle A, Vijayan M, Ramasubramaniam B, et al. A Combination Therapy of Urolithin A+EGCG Has Stronger Protective Effects than Single Drug Urolithin A in a Humanized Amyloid Beta Knockin Mice for Late-Onset Alzheimer's Disease. Cells. 2022;11: pubmed publisher
Vijayan M, Reddy P. Reduced VDAC1, Maintained Mitochondrial Dynamics and Enhanced Mitochondrial Biogenesis in a Transgenic Tau Mouse Model of Alzheimer's Disease. Int J Mol Sci. 2022;23: pubmed publisher
Luk H, Jiwan N, Appell C, Levitt D, Vingren J. Sex-specific mitochondrial dynamics and mitophagy response to muscle damage. Physiol Rep. 2022;10:e15230 pubmed publisher
Ramasubramanian B, Griffith C, Hanson M, Bunquin L, Reddy A, Hegde V, et al. Protective Effects of Chaya against Mitochondrial and Synaptic Toxicities in the Type 2 Diabetes Mouse Model TallyHO. Cells. 2022;11: pubmed publisher
Yan H, Yang H, Wang L, Sun X, Han L, Cong P, et al. Disulfiram inhibits IL-1β secretion and inflammatory cells recruitment in Aspergillus fumigatus keratitis. Int Immunopharmacol. 2022;102:108401 pubmed publisher
Li J, Zhang Z, Wang L, Jiang L, Qin Z, Zhao Y, et al. Maresin 1 Attenuates Lipopolysaccharide-Induced Acute Kidney Injury via Inhibiting NOX4/ROS/NF-κB Pathway. Front Pharmacol. 2021;12:782660 pubmed publisher
Parry H, Randall R, Hyatt H, Hood W, Kavazis A. Short and long-term effect of reproduction on mitochondrial dynamics and autophagy in rats. Heliyon. 2021;7:e08070 pubmed publisher
Reddy A, Sawant N, Morton H, Kshirsagar S, Bunquin L, Yin X, et al. Selective serotonin reuptake inhibitor citalopram ameliorates cognitive decline and protects against amyloid beta-induced mitochondrial dynamics, biogenesis, autophagy, mitophagy and synaptic toxicities in a mouse model of Alzheimer's disease. Hum Mol Genet. 2021;30:789-810 pubmed publisher
Grieco J, Allen M, Perry J, Wang Y, Song Y, Rohani A, et al. Progression-Mediated Changes in Mitochondrial Morphology Promotes Adaptation to Hypoxic Peritoneal Conditions in Serous Ovarian Cancer. Front Oncol. 2020;10:600113 pubmed publisher
Tiku V, Kofoed E, Yan D, Kang J, Xu M, Reichelt M, et al. Outer membrane vesicles containing OmpA induce mitochondrial fragmentation to promote pathogenesis of Acinetobacter baumannii. Sci Rep. 2021;11:618 pubmed publisher
Yazdankhah M, Ghosh S, Shang P, Stepicheva N, Hose S, Liu H, et al. BNIP3L-mediated mitophagy is required for mitochondrial remodeling during the differentiation of optic nerve oligodendrocytes. Autophagy. 2021;:1-20 pubmed publisher
Chen S, Liu S, Wang J, Wu Q, Wang A, Guan H, et al. TBK1-Mediated DRP1 Targeting Confers Nucleic Acid Sensing to Reprogram Mitochondrial Dynamics and Physiology. Mol Cell. 2020;80:810-827.e7 pubmed publisher
Abid H, Ryan Z, Delmotte P, Sieck G, Lanza I. Extramyocellular interleukin-6 influences skeletal muscle mitochondrial physiology through canonical JAK/STAT signaling pathways. FASEB J. 2020;34:14458-14472 pubmed publisher
Teodorof Diedrich C, Spector S. Human Immunodeficiency Virus Type 1 and Methamphetamine-Mediated Mitochondrial Damage and Neuronal Degeneration in Human Neurons. J Virol. 2020;94: pubmed publisher
Mesquita P, Lamb D, Parry H, Moore J, Smith M, Vann C, et al. Acute and chronic effects of resistance training on skeletal muscle markers of mitochondrial remodeling in older adults. Physiol Rep. 2020;8:e14526 pubmed publisher
Panes J, Godoy P, Silva Grecchi T, Celis M, Ramírez Molina O, Gavilan J, et al. Changes in PGC-1α/SIRT1 Signaling Impact on Mitochondrial Homeostasis in Amyloid-Beta Peptide Toxicity Model. Front Pharmacol. 2020;11:709 pubmed publisher
Weatherly L, Shane H, Friend S, Lukomska E, Baur R, Anderson S. Topical Application of the Antimicrobial Agent Triclosan Induces NLRP3 Inflammasome Activation and Mitochondrial Dysfunction. Toxicol Sci. 2020;176:147-161 pubmed publisher
Maremanda K, Sundar I, Rahman I. Protective role of mesenchymal stem cells and mesenchymal stem cell-derived exosomes in cigarette smoke-induced mitochondrial dysfunction in mice. Toxicol Appl Pharmacol. 2019;385:114788 pubmed publisher
Navas Madroñal M, Rodriguez C, Kassan M, Fite J, Escudero J, Cañes L, et al. Enhanced endoplasmic reticulum and mitochondrial stress in abdominal aortic aneurysm. Clin Sci (Lond). 2019;133:1421-1438 pubmed publisher
Zhong X, Cui P, Cai Y, Wang L, He X, Long P, et al. Mitochondrial Dynamics Is Critical for the Full Pluripotency and Embryonic Developmental Potential of Pluripotent Stem Cells. Cell Metab. 2019;29:979-992.e4 pubmed publisher
Pan J, Tang F, Xiong F, Xiong L, Zeng P, Wang B, et al. APP promotes osteoblast survival and bone formation by regulating mitochondrial function and preventing oxidative stress. Cell Death Dis. 2018;9:1077 pubmed publisher
Tarpey M, Davy K, McMillan R, Bowser S, Halliday T, Boutagy N, et al. Skeletal muscle autophagy and mitophagy in endurance-trained runners before and after a high-fat meal. Mol Metab. 2017;6:1597-1609 pubmed publisher
Kandimalla R, Manczak M, Yin X, Wang R, Reddy P. Hippocampal phosphorylated tau induced cognitive decline, dendritic spine loss and mitochondrial abnormalities in a mouse model of Alzheimer's disease. Hum Mol Genet. 2018;27:30-40 pubmed publisher
Vartanian V, Tumová J, Dobrzyn P, Dobrzyn A, Nakabeppu Y, Lloyd R, et al. 8-oxoguanine DNA glycosylase (OGG1) deficiency elicits coordinated changes in lipid and mitochondrial metabolism in muscle. PLoS ONE. 2017;12:e0181687 pubmed publisher
Wang L, Zhang T, Wang L, Cai Y, Zhong X, He X, et al. Fatty acid synthesis is critical for stem cell pluripotency via promoting mitochondrial fission. EMBO J. 2017;36:1330-1347 pubmed publisher
Chan Y, Saad S, Al Odat I, Oliver B, Pollock C, Jones N, et al. Maternal L-Carnitine Supplementation Improves Brain Health in Offspring from Cigarette Smoke Exposed Mothers. Front Mol Neurosci. 2017;10:33 pubmed publisher
Xu S, Wang P, Zhang H, Gong G, Gutiérrez Cortés N, Zhu W, et al. CaMKII induces permeability transition through Drp1 phosphorylation during chronic ?-AR stimulation. Nat Commun. 2016;7:13189 pubmed publisher
Chen H, Chan Y, Nguyen L, Mao Y, de Rosa A, Beh I, et al. Moderate traumatic brain injury is linked to acute behaviour deficits and long term mitochondrial alterations. Clin Exp Pharmacol Physiol. 2016;43:1107-1114 pubmed publisher
Lennon F, Cianci G, Kanteti R, Riehm J, Arif Q, Poroyko V, et al. Unique fractal evaluation and therapeutic implications of mitochondrial morphology in malignant mesothelioma. Sci Rep. 2016;6:24578 pubmed publisher
Zhang M, Sun T, Jian C, Lei L, Han P, Lv Q, et al. Remodeling of Mitochondrial Flashes in Muscular Development and Dystrophy in Zebrafish. PLoS ONE. 2015;10:e0132567 pubmed publisher
Palubinsky A, Stankowski J, Kale A, Codreanu S, Singer R, Liebler D, et al. CHIP Is an Essential Determinant of Neuronal Mitochondrial Stress Signaling. Antioxid Redox Signal. 2015;23:535-49 pubmed publisher
product information
master code :
NB110-55288
SKU :
NB110-55288
product name :
DRP1 Antibody - BSA Free
unit size :
0.1 ml (also 0.025 ml)
description :
The DRP1 Antibody - BSA Free from Novus is a rabbit polyclonal antibody to DRP1. This antibody reacts with fish,human,mouse,primate,rat. The DRP1 Antibody - BSA Free has been validated for the following applications: Immunoprecipitation,Western Blot,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry,Simple Western,IF/IHC,Immunohistochemistry-Paraffin,Flow Cytometry,Flow (Intracellular).
target :
DRP1
category :
Primary Antibodies
buffer :
PBS
clonality :
Polyclonal
concentration :
1 mg/ml
conjugate :
Unconjugated
host :
Rabbit
immunogen :
A synthetic peptide made to an internal region within residues 500-600 of the human DRP1 protein. [Swiss-Prot# O00429]
isotype :
IgG
purity :
Immunogen affinity purified
species :
Fish,Human,Mouse,Primate,Rat
theoretical molecular weight :
81 kDa
gene symbol :
DNM1L
Antibody validation :
Knockout/Knockdown
accessionNumbers :
O00429
applications :
Immunohistochemistry,Western Blot,Immunocytochemistry/ Immunofluorescence,Simple Western,IF/IHC,Immunoprecipitation,Immunohistochemistry-Paraffin,Flow Cytometry,Flow (Intracellular)
USD :
409 USD
alt names :
DLP1, DRP1Dnm1p/Vps1p-like protein, DVLPEC 3.6.5.5, Dymple, DYMPLEDYNIV-11, dynamin 1-like, Dynamin family member proline-rich carboxyl-terminal domain less, dynamin-1-like protein, Dynamin-like protein, Dynamin-like protein 4, Dynamin-like protein IV, Dynamin-related protein 1, FLJ41912, HDYNIV, VPS1
storage :
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.