product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
INSIG-1 Antibody - BSA Free
catalog :
NB110-55244
quantity :
0.1 ml (also 0.025 ml)
price :
409 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
361
reactivity :
human, rat
application :
western blot, immunocytochemistry
more info or order :
citations: 8
Reference
Egawa N, Izumi Y, Suzuki H, Tsuge I, Fujita K, Shimano H, et al. TDP-43 regulates cholesterol biosynthesis by inhibiting sterol regulatory element-binding protein 2. Sci Rep. 2022;12:7988 pubmed publisher
Nakanishi T, Tanaka R, Tonai S, Lee J, Yamaoka M, Kawai T, et al. LH Induces De Novo Cholesterol Biosynthesis via SREBP Activation in Granulosa Cells During Ovulation in Female Mice. Endocrinology. 2021;162: pubmed publisher
Ye L, Lin C, Wang X, Li Q, Li Y, Wang M, et al. Epigenetic silencing of SALL2 confers tamoxifen resistance in breast cancer. EMBO Mol Med. 2019;11:e10638 pubmed publisher
Blee A, He Y, Yang Y, Ye Z, Yan Y, Pan Y, et al. TMPRSS2-ERG Controls Luminal Epithelial Lineage and Antiandrogen Sensitivity in PTEN and TP53-Mutated Prostate Cancer. Clin Cancer Res. 2018;24:4551-4565 pubmed publisher
Zhong J, Ding L, Bohrer L, Pan Y, Liu P, Zhang J, et al. p300 acetyltransferase regulates androgen receptor degradation and PTEN-deficient prostate tumorigenesis. Cancer Res. 2014;74:1870-1880 pubmed publisher
Zhou J, Qin L, Tien J, Gao L, Chen X, Wang F, et al. Nkx3.1 functions as para-transcription factor to regulate gene expression and cell proliferation in non-cell autonomous manner. J Biol Chem. 2012;287:17248-56 pubmed publisher
Gao H, Ouyang X, Banach Petrosky W, Borowsky A, Lin Y, Kim M, et al. A critical role for p27kip1 gene dosage in a mouse model of prostate carcinogenesis. Proc Natl Acad Sci U S A. 2004;101:17204-9 pubmed
Kim M, Cardiff R, Desai N, Banach Petrosky W, Parsons R, Shen M, et al. Cooperativity of Nkx3.1 and Pten loss of function in a mouse model of prostate carcinogenesis. Proc Natl Acad Sci U S A. 2002;99:2884-9 pubmed
product information
master code :
NB110-55244
SKU :
NB110-55244
product name :
INSIG-1 Antibody - BSA Free
unit size :
0.1 ml (also 0.025 ml)
description :
The INSIG-1 Antibody - BSA Free from Novus is a rabbit polyclonal antibody to INSIG-1. This antibody reacts with human,rat. The INSIG-1 Antibody - BSA Free has been validated for the following applications: Western Blot,Immunocytochemistry/ Immunofluorescence.
target :
INSIG-1
category :
Primary Antibodies
buffer :
PBS and 30% Glycerol
clonality :
Polyclonal
concentration :
1.02 mg/ml
conjugate :
Unconjugated
host :
Rabbit
immunogen :
A synthetic peptide representing an internal region of the human INSIG-1 protein (between residues 1-100) according to Swiss-Prot# O15503.
isotype :
IgG
purity :
Immunogen affinity purified
species :
Human,Rat
specificity :
This is specific for Insig1 but not Insig2
theoretical molecular weight :
30 kDa
gene symbol :
INSIG1
applications :
Western Blot,Immunocytochemistry/ Immunofluorescence
USD :
409 USD
alt names :
CL6, CL-6, INSIG-1, INSIG-1 membrane protein, insulin induced gene 1, insulin-induced gene 1 protein, MGC1405
storage :
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.