product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
ATG5 Antibody - BSA Free
catalog :
NB110-53818
quantity :
0.1 ml (also 0.025 ml)
price :
469 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
DyLight488
clone name :
OTI2B3
reactivity :
guinea pig, human, mouse, bovine, zebrafish
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, radioimmunoassay, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, proximity ligation assay, western blot knockout validation, immunohistochemistry knockout validation
more info or order :
citations: 190
Published Application/Species/Sample/DilutionReference
  • western blot knockout validation; human; 1:500; loading ...; fig s6d
Wijshake T, Zou Z, Chen B, Zhong L, Xiao G, Xie Y, et al. Tumor-suppressor function of Beclin 1 in breast cancer cells requires E-cadherin. Proc Natl Acad Sci U S A. 2021;118: pubmed publisher
  • immunohistochemistry knockout validation; mouse; loading ...; fig s1
  • immunohistochemistry - paraffin section; mouse; loading ...; fig s1
Bechelli J, Vergara L, Smalley C, Buzhdygan T, Bender S, Zhang W, et al. Atg5 Supports Rickettsia australis Infection in Macrophages In Vitro and In Vivo. Infect Immun. 2019;87: pubmed publisher
  • immunocytochemistry; human; 1:100; loading ...; fig 3b
  • immunohistochemistry; mouse; 1:100; loading ...; fig 4f
  • western blot; mouse; 1:1000; loading ...; fig 3c
Tripathi P, Guo H, Dreser A, Yamoah A, Sechi A, Jesse C, et al. Pathomechanisms of ALS8: altered autophagy and defective RNA binding protein (RBP) homeostasis due to the VAPB P56S mutation. Cell Death Dis. 2021;12:466 pubmed publisher
  • western blot; mouse; 1:1000; loading ...
Caballero B, Bourdenx M, Luengo E, Díaz A, Sohn P, Chen X, et al. Acetylated tau inhibits chaperone-mediated autophagy and promotes tau pathology propagation in mice. Nat Commun. 2021;12:2238 pubmed publisher
  • western blot; zebrafish ; loading ...; fig 1a
Hu Z, Chen B, Zhao Q. Hedgehog signaling regulates osteoblast differentiation in zebrafish larvae through modulation of autophagy. Biol Open. 2019;8: pubmed publisher
  • western blot; guinea pig; loading ...; fig 7b
Zhang Y, Jiang Q, Xie S, Wu X, Zhou J, Sun H. Lead Induced Ototoxicity and Neurotoxicity in Adult Guinea Pig. Biomed Res Int. 2019;2019:3626032 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 5a
Cai Y, Yang L, Hu G, Chen X, Niu F, Yuan L, et al. Regulation of morphine-induced synaptic alterations: Role of oxidative stress, ER stress, and autophagy. J Cell Biol. 2016;215:245-258 pubmed
  • western blot; mouse; 1:2000; loading ...; fig s1a
Starobinets H, Ye J, Broz M, Barry K, Goldsmith J, Marsh T, et al. Antitumor adaptive immunity remains intact following inhibition of autophagy and antimalarial treatment. J Clin Invest. 2016;126:4417-4429 pubmed publisher
  • western blot; mouse; fig 9
Song J, Sun Y, Peluso I, Zeng Y, Yu X, Lu J, et al. A novel curcumin analog binds to and activates TFEB in vitro and in vivo independent of MTOR inhibition. Autophagy. 2016;12:1372-89 pubmed publisher
  • western blot; bovine; fig 2b
Xia X, Che Y, Gao Y, Zhao S, Ao C, Yang H, et al. Arginine Supplementation Recovered the IFN-?-Mediated Decrease in Milk Protein and Fat Synthesis by Inhibiting the GCN2/eIF2? Pathway, Which Induces Autophagy in Primary Bovine Mammary Epithelial Cells. Mol Cells. 2016;39:410-7 pubmed publisher
Park N, Jo D, Park H, Bae J, Kim Y, Kim J, et al. Deciphering melanophagy: role of the PTK2-ITCH-MLANA-OPTN cascade on melanophagy in melanocytes. Autophagy. 2025;21:664-673 pubmed publisher
Marchese M, Bernardi S, Ogi A, Licitra R, Silvi G, Mero S, et al. Targeting autophagy impairment improves the phenotype of a novel CLN8 zebrafish model. Neurobiol Dis. 2024;197:106536 pubmed publisher
Jiang Z, He Q, Wezeman J, Darvas M, Ladiges W. A cocktail of rapamycin, acarbose, and phenylbutyrate prevents age-related cognitive decline in mice by targeting multiple aging pathways. GeroScience. 2024;46:4855-4868 pubmed publisher
Sung H, Tang J, Jahng J, Song E, Chan Y, Lone A, et al. Ischemia-induced cardiac dysfunction is exacerbated in adiponectin-knockout mice due to impaired autophagy flux. Clin Transl Sci. 2024;17:e13758 pubmed publisher
Fan R, Sportelli C, Lai Y, Salehe S, Pinnell J, Brown H, et al. A partial Drp1 knockout improves autophagy flux independent of mitochondrial function. Mol Neurodegener. 2024;19:26 pubmed publisher
Bai L, Zhang R, Zheng H, Zhang Z, Zhang Z, Li Y. Seneca Valley Virus Degrades STING via PERK and ATF6-Mediated Reticulophagy. Viruses. 2023;15: pubmed publisher
Mart xed nez Gonz xe1 lez J, Fern xe1 ndez Carbonell x, Cant xf3 A, Gimeno Hern xe1 ndez R, Almansa I, Bosch Morell F, et al. Sequences of Alterations in Inflammation and Autophagy Processes in Rd1 Mice. Biomolecules. 2023;13: pubmed publisher
Keary K, Gu Q, Chen J, Li Z. Dendritic distribution of autophagosomes underlies pathway-selective induction of LTD. Cell Rep. 2023;42:112898 pubmed publisher
Sakurai H, Iwashita H, Arakawa S, Yikelamu A, Kusaba M, Kofuji S, et al. Development of small fluorescent probes for the analysis of autophagy kinetics. iScience. 2023;26:107218 pubmed publisher
Pan Y, Yang Y, Fan M, Chen C, Jiang R, Liang L, et al. Progranulin regulation of autophagy contributes to its chondroprotective effect in osteoarthritis. Genes Dis. 2023;10:1582-1595 pubmed publisher
Macke A, Pachikov A, Divita T, Morris M, Lagrange C, Holzapfel M, et al. Targeting the ATF6-Mediated ER Stress Response and Autophagy Blocks Integrin-Driven Prostate Cancer Progression. Mol Cancer Res. 2023;21:958-974 pubmed publisher
Mitsui K, Hishiyama S, Jain A, Kotoda Y, Abe M, Matsukawa T, et al. Role of macrophage autophagy in postoperative pain and inflammation in mice. J Neuroinflammation. 2023;20:102 pubmed publisher
Mukhopadhyay S, Encarnaci xf3 n Rosado J, Lin E, Sohn A, Zhang H, Mancias J, et al. Autophagy supports mitochondrial metabolism through the regulation of iron homeostasis in pancreatic cancer. Sci Adv. 2023;9:eadf9284 pubmed publisher
Bi Y, Yang G, Guo Z, Cai W, Chen S, Zhou X, et al. Chronic high‑salt intake induces cardiomyocyte autophagic vacuolization during left ventricular maladaptive remodeling in spontaneously hypertensive rats. Exp Ther Med. 2023;25:148 pubmed publisher
Wan W, Qian C, Wang Q, Li J, Zhang H, Wang L, et al. STING directly recruits WIPI2 for autophagosome formation during STING-induced autophagy. EMBO J. 2023;42:e112387 pubmed publisher
Liao Y, Wu J, Hsieh I, Lee H, Huang P. ARMS-NF-κB signaling regulates intracellular ROS to induce autophagy-associated cell death upon oxidative stress. iScience. 2023;26:106005 pubmed publisher
Lee H, Kim S, Kim Y, Kim S, Oh G, Bae J, et al. Nalfurafine Hydrochloride, a κ-Opioid Receptor Agonist, Induces Melanophagy via PKA Inhibition in B16F1 Cells. Cells. 2022;12: pubmed publisher
Ktena N, Kaplanis S, Kolotuev I, Georgilis A, Kallergi E, Stavroulaki V, et al. Autophagic degradation of CNS myelin maintains axon integrity. Cell Stress. 2022;6:93-107 pubmed publisher
Alan P, Vandevoorde K, Joshi B, Cardoen B, Gao G, Mohammadzadeh Y, et al. Basal Gp78-dependent mitophagy promotes mitochondrial health and limits mitochondrial ROS. Cell Mol Life Sci. 2022;79:565 pubmed publisher
Li L, Zhang M, Li S, Jiang B, Zhang J, Yu L, et al. Isatropolone/isarubrolone Cm from Streptomyces with biological activity of inducing incomplete autophagy. J Antibiot (Tokyo). 2022;75:702-708 pubmed publisher
Zhang R, Lin H, You Q, Zhang Z, Bai L, Chen F, et al. Peste des Petits Ruminants Virus Upregulates STING to Activate ATF6-Mediated Autophagy. J Virol. 2022;96:e0137522 pubmed publisher
Seo H, Choi H, Kim O, Park J, Hong H, Kim S. The secretome obtained under hypoxic preconditioning from human adipose-derived stem cells exerts promoted anti-apoptotic potentials through upregulated autophagic process. Mol Biol Rep. 2022;49:8859-8870 pubmed publisher
Wen Y, Chen Z, Tian Y, Yang M, Dong Q, Yang Y, et al. Incomplete autophagy promotes the proliferation of Mycoplasma hyopneumoniae through the JNK and Akt pathways in porcine alveolar macrophages. Vet Res. 2022;53:62 pubmed publisher
Bai J, Liu T, Tu B, Yuan M, Shu Z, Fan M, et al. Autophagy Loss Impedes Cancer-Associated Fibroblast Activation via Downregulating Proline Biosynthesis. Autophagy. 2022;: pubmed publisher
Della Vecchia S, Ogi A, Licitra R, Abramo F, Nardi G, Mero S, et al. Trehalose Treatment in Zebrafish Model of Lafora Disease. Int J Mol Sci. 2022;23: pubmed publisher
Cardinali B, De Luca G, Tasso R, Coco S, Garuti A, Buzzatti G, et al. Targeting PIK3CA Actionable Mutations in the Circulome: A Proof of Concept in Metastatic Breast Cancer. Int J Mol Sci. 2022;23: pubmed publisher
Jiang R, Shimozawa M, Mayer J, Tambaro S, Kumar R, Abelein A, et al. Autophagy Impairment in App Knock-in Alzheimer's Model Mice. Front Aging Neurosci. 2022;14:878303 pubmed publisher
Chua J, Bedi K, Paulsen M, Ljungman M, Tank E, Kim E, et al. Myotubularin-related phosphatase 5 is a critical determinant of autophagy in neurons. Curr Biol. 2022;32:2581-2595.e6 pubmed publisher
Chimenti I, Picchio V, Pagano F, Schirone L, Schiavon S, D Ambrosio L, et al. The impact of autophagy modulation on phenotype and survival of cardiac stromal cells under metabolic stress. Cell Death Discov. 2022;8:149 pubmed publisher
Kao C, Su T, Huang W, Lu X, Jane W, Huang C, et al. TFEB- and TFE3-dependent autophagy activation supports cancer proliferation in the absence of centrosomes. Autophagy. 2022;:1-21 pubmed publisher
Lim J, Hyun S. Minocycline treatment improves proteostasis during Drosophila aging via autophagy mediated by FOXO and Hsp70. Biomed Pharmacother. 2022;149:112803 pubmed publisher
Izumi H, Li Y, Yasunami M, Sato S, Mae T, Kaneko Y, et al. Asymmetric Pericentrosomal CD133 Endosomes Induce the Unequal Autophagic Activity During Cytokinesis in CD133-Positive Human Neuroblastoma Cells. Stem Cells. 2022;40:371-384 pubmed publisher
Chen Y, Chen S, Li T, Lin T, Chen C, Yen G. 4-Acetylantroquinonol B enhances cell death and inhibits autophagy by downregulating the PI3K/Akt/MDR1 pathway in gemcitabine-resistant pancreatic cancer cells. Oncol Lett. 2022;23:128 pubmed publisher
Chaouhan H, Li X, Sun K, Wang I, Yu T, Yu S, et al. Calycosin Alleviates Paraquat-Induced Neurodegeneration by Improving Mitochondrial Functions and Regulating Autophagy in a Drosophila Model of Parkinson's Disease. Antioxidants (Basel). 2022;11: pubmed publisher
Ji C, Kim H, Lee M, Heo A, Park D, Lim S, et al. The AUTOTAC chemical biology platform for targeted protein degradation via the autophagy-lysosome system. Nat Commun. 2022;13:904 pubmed publisher
Dong J, Yue K, Loor J, Aboragah A, Li G, Chen L, et al. Increased adipose tissue lipolysis in dairy cows with fatty liver is associated with enhanced autophagy activity. J Dairy Sci. 2022;105:1731-1742 pubmed publisher
Hsu M, Guo B, Chen C, Hu P, Lee T. Apigenin ameliorates hepatic lipid accumulation by activating the autophagy-mitochondria pathway. J Food Drug Anal. 2021;29:240-254 pubmed publisher
Irace F, Cammisotto V, Valenti V, Forte M, Schirone L, Bartimoccia S, et al. Role of Oxidative Stress and Autophagy in Thoracic Aortic Aneurysms. JACC Basic Transl Sci. 2021;6:719-730 pubmed publisher
Peng Z, Zhao C, Du X, Yang Y, Li Y, Song Y, et al. Autophagy Induced by Palmitic Acid Regulates Neutrophil Adhesion Through the Granule-Dependent Degradation of αMβ2 Integrin in Dairy Cows With Fatty Liver. Front Immunol. 2021;12:726829 pubmed publisher
López Pedrajas R, Almansa I, Sanchez Villarejo M, Muriach B, Barcia J, Romero F, et al. Role of hippocampal NF-κB and GluN2B in the memory acquisition impairment of experiences gathered prior to cocaine administration in rats. Sci Rep. 2021;11:20033 pubmed publisher
Parry H, Randall R, Hyatt H, Hood W, Kavazis A. Short and long-term effect of reproduction on mitochondrial dynamics and autophagy in rats. Heliyon. 2021;7:e08070 pubmed publisher
Xu Y, Wu Y, Wang L, Ren Z, Song L, Zhang H, et al. Autophagy deficiency activates rDNA transcription. Autophagy. 2021;:1-12 pubmed publisher
Sekiguchi K, Miyahara H, Inoue M, Kiyota K, Sakai K, Hanada T, et al. Metabolome Characteristics of Liver Autophagy Deficiency under Starvation Conditions in Infancy. Nutrients. 2021;13: pubmed publisher
Ross B, Jia L, Kong D, Wang T, Hager H, ABCOUWER S, et al. Conditional Knock out of High-Mobility Group Box 1 (HMGB1) in Rods Reduces Autophagy Activation after Retinal Detachment. Cells. 2021;10: pubmed publisher
Bains H, Singh R. Isolation of autophagic fractions from mouse liver for biochemical analyses. STAR Protoc. 2021;2:100730 pubmed publisher
Rudnick J, Monkkonen T, Mar F, Barnes J, Starobinets H, Goldsmith J, et al. Autophagy in stromal fibroblasts promotes tumor desmoplasia and mammary tumorigenesis. Genes Dev. 2021;35:963-975 pubmed publisher
Moroki T, Matsuo S, Hatakeyama H, Hayashi S, Matsumoto I, Suzuki S, et al. Databases for technical aspects of immunohistochemistry: 2021 update. J Toxicol Pathol. 2021;34:161-180 pubmed publisher
Shi M, Shepard S, Zhou Z, Maique J, Seli O, Moe O, et al. High Dietary Phosphate Exacerbates and Acts Independently of Low Autophagy Activity in Pathological Cardiac Remodeling and Dysfunction. Cells. 2021;10: pubmed publisher
Inoue M, Miyahara H, Shiraishi H, Shimizu N, Tsumori M, Kiyota K, et al. Leucyl-tRNA synthetase deficiency systemically induces excessive autophagy in zebrafish. Sci Rep. 2021;11:8392 pubmed publisher
Wang X, Pei Z, Hossain A, Bai Y, Chen G. Transcription factor-based gene therapy to treat glioblastoma through direct neuronal conversion. Cancer Biol Med. 2021;: pubmed publisher
Xiao J, Yao J, Jia L, Ferguson T, Weber S, Sundstrom J, et al. Autophagy activation and photoreceptor survival in retinal detachment. Exp Eye Res. 2021;205:108492 pubmed publisher
Zheng J, Hu S, Wang J, Zhang X, Yuan D, Zhang C, et al. Icariin improves brain function decline in aging rats by enhancing neuronal autophagy through the AMPK/mTOR/ULK1 pathway. Pharm Biol. 2021;59:183-191 pubmed publisher
Annangi B, Lu Z, Bruniaux J, Ridoux A, da Silva V, Vantelon D, et al. Macrophage autophagy protects mice from cerium oxide nanoparticle-induced lung fibrosis. Part Fibre Toxicol. 2021;18:6 pubmed publisher
Chao T, Shih H, Hsu S, Chen P, Fan Y, Jeng Y, et al. Autophagy restricts mitochondrial DNA damage-induced release of ENDOG (endonuclease G) to regulate genome stability. Autophagy. 2021;:1-17 pubmed publisher
Zhu E, Wu H, Chen W, Qin Y, Liu J, Fan S, et al. Classical swine fever virus employs the PERK- and IRE1-dependent autophagy for viral replication in cultured cells. Virulence. 2021;12:130-149 pubmed publisher
Gu Q, Jiao S, Duan K, Wang Y, Petralia R, Li Z. The BAD-BAX-Caspase-3 Cascade Modulates Synaptic Vesicle Pools via Autophagy. J Neurosci. 2021;41:1174-1190 pubmed publisher
Pareja Cajiao M, Gransee H, Stowe J, Rana S, Sieck G, Mantilla C. Age-related impairment of autophagy in cervical motor neurons. Exp Gerontol. 2021;144:111193 pubmed publisher
Hwang J, Kim W, Cho Y, Ryu J, Choi J, Jeong S, et al. Chloroquine reverses chemoresistance via upregulation of p21WAF1/CIP1 and autophagy inhibition in ovarian cancer. Cell Death Dis. 2020;11:1034 pubmed publisher
Cui L, Song W, Zeng Y, Wu Q, Fan Z, Huang T, et al. Deubiquitinase USP7 regulates Drosophila aging through ubiquitination and autophagy. Aging (Albany NY). 2020;12:23082-23095 pubmed publisher
Her J, Lee Y, Kim S, Heo G, Choo J, Kim Y, et al. Blockage of protease-activated receptor 2 exacerbates inflammation in high-fat environment partly through autophagy inhibition. Am J Physiol Gastrointest Liver Physiol. 2021;320:G30-G42 pubmed publisher
Lee D, Park S, Ahn J, Hong S, Lee E, Jang Y, et al. Mir214-3p and Hnf4a/Hnf4α reciprocally regulate Ulk1 expression and autophagy in nonalcoholic hepatic steatosis. Autophagy. 2020;:1-17 pubmed publisher
Bressan C, Pecora A, Gagnon D, Snapyan M, Labrecque S, De Koninck P, et al. The dynamic interplay between ATP/ADP levels and autophagy sustain neuronal migration in vivo. elife. 2020;9: pubmed publisher
Park H, Jo D, Choi H, Bae J, Park N, Kim J, et al. Melasolv induces melanosome autophagy to inhibit pigmentation in B16F1 cells. PLoS ONE. 2020;15:e0239019 pubmed publisher
Miceli C, Roccio F, Penalva Mousset L, Burtin M, Leroy C, Nemazanyy I, et al. The primary cilium and lipophagy translate mechanical forces to direct metabolic adaptation of kidney epithelial cells. Nat Cell Biol. 2020;22:1091-1102 pubmed publisher
Mukhopadhyay S, Praharaj P, Naik P, Talukdar S, Emdad L, Das S, et al. Identification of Annexin A2 as a key mTOR target to induce roller coaster pattern of autophagy fluctuation in stress. Biochim Biophys Acta Mol Basis Dis. 2020;1866:165952 pubmed publisher
Park H, Jo D, Choi D, Bae J, Park N, Kim J, et al. Ursolic acid inhibits pigmentation by increasing melanosomal autophagy in B16F1 cells. Biochem Biophys Res Commun. 2020;531:209-214 pubmed publisher
Fiorito F, Nocera F, Cantiello A, Iovane V, Lambiase S, Piccolo M, et al. Bovine herpesvirus-1 infection in mouse neuroblastoma (Neuro-2A) cells. Vet Microbiol. 2020;247:108762 pubmed publisher
Goldsmith J, Marsh T, Asthana S, Leidal A, Suresh D, Olshen A, et al. Ribosome profiling reveals a functional role for autophagy in mRNA translational control. Commun Biol. 2020;3:388 pubmed publisher
Han K, Kang R, Jeon H, Lee H, Lee J, Park H, et al. Regorafenib Regulates AD Pathology, Neuroinflammation, and Dendritic Spinogenesis in Cells and a Mouse Model of AD. Cells. 2020;9: pubmed publisher
Park S, Choi H, Ahn J, Jang Y, Ha T, Seo H, et al. Autophagy Functions to Prevent Methylglyoxal-Induced Apoptosis in HK-2 Cells. Oxid Med Cell Longev. 2020;2020:8340695 pubmed publisher
Shen H, Zhu H, Panja D, Gu Q, Li Z. Autophagy controls the induction and developmental decline of NMDAR-LTD through endocytic recycling. Nat Commun. 2020;11:2979 pubmed publisher
Yefimova M, Lefevre C, Bashamboo A, Eozenou C, Burel A, Lavault M, et al. Granulosa cells provide elimination of apoptotic oocytes through unconventional autophagy-assisted phagocytosis. Hum Reprod. 2020;35:1346-1362 pubmed publisher
Karuppan M, Ojha C, Rodriguez M, Lapierre J, Aman M, Kashanchi F, et al. Reduced-Beclin1-Expressing Mice Infected with Zika-R103451 and Viral-Associated Pathology during Pregnancy. Viruses. 2020;12: pubmed publisher
Dutta K, Thammisetty S, Boutej H, Bareil C, Julien J. Mitigation of ALS Pathology by Neuron-Specific Inhibition of Nuclear Factor Kappa B Signaling. J Neurosci. 2020;40:5137-5154 pubmed publisher
Liao K, Niu F, Hu G, Guo M, Sil S, Buch S. HIV Tat-mediated induction of autophagy regulates the disruption of ZO-1 in brain endothelial cells. Tissue Barriers. 2020;:1748983 pubmed publisher
Mawed S, He Y, Zhang J, Mei J. Strategy of Hepatic Metabolic Defects Induced by beclin1 Heterozygosity in Adult Zebrafish. Int J Mol Sci. 2020;21: pubmed publisher
Marsh T, Kenific C, Suresh D, Gonzalez H, Shamir E, Mei W, et al. Autophagic Degradation of NBR1 Restricts Metastatic Outgrowth during Mammary Tumor Progression. Dev Cell. 2020;52:591-604.e6 pubmed publisher
Hale A, Merchant M, White M. Detection and analysis of autophagy in the American alligator (Alligator mississippiensis). J Exp Zool B Mol Dev Evol. 2020;334:192-207 pubmed publisher
Chen M, Loor J, Zhai Q, Liang Y, Yu H, Du X, et al. Short communication: Enhanced autophagy activity in liver tissue of dairy cows with mild fatty liver. J Dairy Sci. 2020;103:3628-3635 pubmed publisher
Takagaki Y, Lee S, Dongqing Z, Kitada M, Kanasaki K, Koya D. Endothelial autophagy deficiency induces IL6 - dependent endothelial mesenchymal transition and organ fibrosis. Autophagy. 2020;:1-10 pubmed publisher
Bekbulat F, Schmitt D, Feldmann A, Huesmann H, Eimer S, Juretschke T, et al. RAB18 Loss Interferes With Lipid Droplet Catabolism and Provokes Autophagy Network Adaptations. J Mol Biol. 2020;432:1216-1234 pubmed publisher
An H, Chung K, Park H, Hong J, Gim J, Choi H, et al. CASP9 (caspase 9) is essential for autophagosome maturation through regulation of mitochondrial homeostasis. Autophagy. 2019;:1-20 pubmed publisher
Zhu E, Chen W, Qin Y, Ma S, Fan S, Wu K, et al. Classical Swine Fever Virus Infection Induces Endoplasmic Reticulum Stress-Mediated Autophagy to Sustain Viral Replication in vivo and in vitro. Front Microbiol. 2019;10:2545 pubmed publisher
Liu Y, Lai Y, Lin H, Chen J. Lotus Seedpod Extracts Reduced Lipid Accumulation and Lipotoxicity in Hepatocytes. Nutrients. 2019;11: pubmed publisher
Su B, Hsu P, Mo F. CCN1 triggers adaptive autophagy in cardiomyocytes to curb its apoptotic activities. J Cell Commun Signal. 2020;14:93-100 pubmed publisher
Wible D, Chao H, Tang D, Bratton S. ATG5 cancer mutations and alternative mRNA splicing reveal a conjugation switch that regulates ATG12-ATG5-ATG16L1 complex assembly and autophagy. Cell Discov. 2019;5:42 pubmed publisher
Sun C, Enkhjargal B, Reis C, Zhang T, Zhu Q, Zhou K, et al. Osteopontin-Enhanced Autophagy Attenuates Early Brain Injury via FAK-ERK Pathway and Improves Long-Term Outcome after Subarachnoid Hemorrhage in Rats. Cells. 2019;8: pubmed publisher
Sun C, Enkhjargal B, Reis C, Zhou K, Xie Z, Wu L, et al. Osteopontin attenuates early brain injury through regulating autophagy-apoptosis interaction after subarachnoid hemorrhage in rats. CNS Neurosci Ther. 2019;25:1162-1172 pubmed publisher
Koerver L, Papadopoulos C, Liu B, Kravic B, Rota G, Brecht L, et al. The ubiquitin-conjugating enzyme UBE2QL1 coordinates lysophagy in response to endolysosomal damage. EMBO Rep. 2019;20:e48014 pubmed publisher
Chiramel A, Meyerson N, McNally K, Broeckel R, Montoya V, Méndez Solís O, et al. TRIM5α Restricts Flavivirus Replication by Targeting the Viral Protease for Proteasomal Degradation. Cell Rep. 2019;27:3269-3283.e6 pubmed publisher
Bankston A, Forston M, Howard R, Andres K, Smith A, Ohri S, et al. Autophagy is essential for oligodendrocyte differentiation, survival, and proper myelination. Glia. 2019;: pubmed publisher
Lee H, Lee J, Hwang D, Lee G, Kim N, Kwon M, et al. Dehydrocostus lactone suppresses osteoclast differentiation by regulating NFATc1 and inhibits osteoclast activation through modulating migration and lysosome function. FASEB J. 2019;33:9685-9694 pubmed publisher
Das J, Agarwal T, Chakraborty S, Maiti T. Compressive stress-induced autophagy promotes invasion of HeLa cells by facilitating protein turnover in vitro. Exp Cell Res. 2019;381:201-207 pubmed publisher
Li L, Li S, Jiang B, Zhang M, Zhang J, Yang B, et al. Isarubrolones Containing a Pyridooxazinium Unit from Streptomyces as Autophagy Activators. J Nat Prod. 2019;82:1149-1154 pubmed publisher
Zheng W, Xie W, Yin D, Luo R, Liu M, Guo F. ATG5 and ATG7 induced autophagy interplays with UPR via PERK signaling. Cell Commun Signal. 2019;17:42 pubmed publisher
Shin J, Park S, Jo D, Park N, Kim J, Bae J, et al. Down-regulated TMED10 in Alzheimer disease induces autophagy via ATG4B activation. Autophagy. 2019;:1-11 pubmed publisher
You Z, Xu Y, Wan W, Zhou L, Li J, Zhou T, et al. TP53INP2 contributes to autophagosome formation by promoting LC3-ATG7 interaction. Autophagy. 2019;15:1309-1321 pubmed publisher
Bonello F, Hassoun S, Mouton Liger F, Shin Y, Muscat A, Tesson C, et al. LRRK2 impairs PINK1/Parkin-dependent mitophagy via its kinase activity: pathologic insights into Parkinson's disease. Hum Mol Genet. 2019;28:1645-1660 pubmed publisher
Kong D, Hua X, Qin T, Zhang J, He K, Xia Q. Inhibition of glycogen synthase kinase 3β protects liver against ischemia/reperfusion injury by activating 5' adenosine monophosphate-activated protein kinase-mediated autophagy. Hepatol Res. 2019;49:462-472 pubmed publisher
Choi G, Oh J, Lee H, Chae C, Kim J, Jung Y, et al. Glucocorticoid-mediated ER-mitochondria contacts reduce AMPA receptor and mitochondria trafficking into cell terminus via microtubule destabilization. Cell Death Dis. 2018;9:1137 pubmed publisher
Wan W, You Z, Zhou L, Xu Y, Peng C, Zhou T, et al. mTORC1-Regulated and HUWE1-Mediated WIPI2 Degradation Controls Autophagy Flux. Mol Cell. 2018;72:303-315.e6 pubmed publisher
Gorgulu K, Diakopoulos K, Ai J, Schoeps B, Kabacaoglu D, Karpathaki A, et al. Levels of the Autophagy-Related 5 Protein Affect Progression and Metastasis of Pancreatic Tumors in Mice. Gastroenterology. 2019;156:203-217.e20 pubmed publisher
Ye T, Jiang K, Wei L, Barr M, Xu Q, Zhang G, et al. Oncolytic Newcastle disease virus induces autophagy-dependent immunogenic cell death in lung cancer cells. Am J Cancer Res. 2018;8:1514-1527 pubmed
Arbogast F, Arnold J, Hammann P, Kuhn L, Chicher J, Murera D, et al. ATG5 is required for B cell polarization and presentation of particulate antigens. Autophagy. 2019;15:280-294 pubmed publisher
Jiang Z, Bo L, Meng Y, Wang C, Chen T, Wang C, et al. Overexpression of homeodomain-interacting protein kinase 2 (HIPK2) attenuates sepsis-mediated liver injury by restoring autophagy. Cell Death Dis. 2018;9:847 pubmed publisher
Dutta K, Patel P, Julien J. Protective effects of Withania somnifera extract in SOD1G93A mouse model of amyotrophic lateral sclerosis. Exp Neurol. 2018;309:193-204 pubmed publisher
Li D, Wang C, Li Z, Wang H, He J, Zhu J, et al. Nano-sized Al2O3 particle-induced autophagy reduces osteolysis in aseptic loosening of total hip arthroplasty by negative feedback regulation of RANKL expression in fibroblasts. Cell Death Dis. 2018;9:840 pubmed publisher
Lin H, Chung Y, Cheng C, Ouyang C, Fu Y, Kuo C, et al. Autophagic reliance promotes metabolic reprogramming in oncogenic KRAS-driven tumorigenesis. Autophagy. 2018;14:1481-1498 pubmed publisher
Yao J, Qiu Y, Frontera E, Jia L, Khan N, Klionsky D, et al. Inhibiting autophagy reduces retinal degeneration caused by protein misfolding. Autophagy. 2018;14:1226-1238 pubmed publisher
Park S, Lim J, Ramakrishina S, Kim S, Kim W, Lee J, et al. Brain Somatic Mutations in MTOR Disrupt Neuronal Ciliogenesis, Leading to Focal Cortical Dyslamination. Neuron. 2018;99:83-97.e7 pubmed publisher
Chen P, Liu A, Ho K, Chiu Y, Anne Lin Z, Lee Y, et al. microRNA-199a/b-5p enhance imatinib efficacy via repressing WNT2 signaling-mediated protective autophagy in imatinib-resistant chronic myeloid leukemia cells. Chem Biol Interact. 2018;291:144-151 pubmed publisher
Wu X, Chen W, Hu Y, Cao L, Nie P, Chang M. RIP2 Is a Critical Regulator for NLRs Signaling and MHC Antigen Presentation but Not for MAPK and PI3K/Akt Pathways. Front Immunol. 2018;9:726 pubmed publisher
Nanni M, Ranieri D, Rosato B, Torrisi M, Belleudi F. Role of Fibroblast Growth Factor Receptor 2b in the Cross Talk between Autophagy and Differentiation: Involvement of Jun N-Terminal Protein Kinase Signaling. Mol Cell Biol. 2018;38: pubmed publisher
Murera D, Arbogast F, Arnold J, Bouis D, Muller S, Gros F. CD4 T cell autophagy is integral to memory maintenance. Sci Rep. 2018;8:5951 pubmed publisher
Kim Y, Kwak M, Shin J, Hayuningtyas R, Choi J, Shin J. Inflachromene inhibits autophagy through modulation of Beclin 1 activity. J Cell Sci. 2018;131: pubmed publisher
Shim S, Choi H, Sung K, Lee Y, Kim S, Kim D, et al. The endoplasmic reticulum-residing chaperone BiP is short-lived and metabolized through N-terminal arginylation. Sci Signal. 2018;11: pubmed publisher
Xia X, Wang L, Zhang X, Wang S, Lei L, Cheng L, et al. Halofuginone-induced Autophagy Suppresses the Migration and Invasion of MCF-7 Cells via Regulation of STMN1 and p53. J Cell Biochem. 2017;: pubmed publisher
Byun Y, Lee H, Shin S, Chung S. Elevation of autophagy markers in Sjögren syndrome dry eye. Sci Rep. 2017;7:17280 pubmed publisher
Yang P, Hsieh M, Chang Y, Huang P, Lee J. Genetic polymorphisms of ATG5 predict survival and recurrence in patients with early-stage esophageal squamous cell carcinoma. Oncotarget. 2017;8:91494-91504 pubmed publisher
Baron O, Boudi A, Dias C, Schilling M, Nölle A, Vizcay Barrena G, et al. Stall in Canonical Autophagy-Lysosome Pathways Prompts Nucleophagy-Based Nuclear Breakdown in Neurodegeneration. Curr Biol. 2017;27:3626-3642.e6 pubmed publisher
Sun P, Zhang S, Qin X, Chang X, Cui X, Li H, et al. Foot-and-mouth disease virus capsid protein VP2 activates the cellular EIF2S1-ATF4 pathway and induces autophagy via HSPB1. Autophagy. 2018;14:336-346 pubmed publisher
Martínez López N, Tarabra E, Toledo M, García Macia M, Sahu S, Coletto L, et al. System-wide Benefits of Intermeal Fasting by Autophagy. Cell Metab. 2017;26:856-871.e5 pubmed publisher
Fiorito F, Iovane V, Cantiello A, Marullo A, De Martino L, Iovane G. MG-132 reduces virus release in Bovine herpesvirus-1 infection. Sci Rep. 2017;7:13306 pubmed publisher
Kuss Duerkop S, Wang J, Mena I, White K, Metreveli G, Sakthivel R, et al. Influenza virus differentially activates mTORC1 and mTORC2 signaling to maximize late stage replication. PLoS Pathog. 2017;13:e1006635 pubmed publisher
Meckes J, Caramés B, Olmer M, Kiosses W, Grogan S, Lotz M, et al. Compromised autophagy precedes meniscus degeneration and cartilage damage in mice. Osteoarthritis Cartilage. 2017;25:1880-1889 pubmed publisher
Mans L, Querol Cano L, van Pelt J, Giardoglou P, Keune W, Haramis A. The tumor suppressor LKB1 regulates starvation-induced autophagy under systemic metabolic stress. Sci Rep. 2017;7:7327 pubmed publisher
Zhang R, Xu J, Zhao J, Bai J. Mir-30d suppresses cell proliferation of colon cancer cells by inhibiting cell autophagy and promoting cell apoptosis. Tumour Biol. 2017;39:1010428317703984 pubmed publisher
Li Z, Yuan Y, Meng Y, Rong Y, Bai H, Chen L. Autophagy upregulation ameliorates cell injury in Sequestosome 1 knockout podocytes in vitro. Biochem Biophys Res Commun. 2017;490:98-103 pubmed publisher
Hine C, Kim H, Zhu Y, Harputlugil E, Longchamp A, Matos M, et al. Hypothalamic-Pituitary Axis Regulates Hydrogen Sulfide Production. Cell Metab. 2017;25:1320-1333.e5 pubmed publisher
Zielniok K, Sobolewska A, Gajewska M. Mechanisms of autophagy induction by sex steroids in bovine mammary epithelial cells. J Mol Endocrinol. 2017;59:29-48 pubmed publisher
Sathyanarayan A, Mashek M, Mashek D. ATGL Promotes Autophagy/Lipophagy via SIRT1 to Control Hepatic Lipid Droplet Catabolism. Cell Rep. 2017;19:1-9 pubmed publisher
Zhu L, Wang H, Wu Y, He Z, Qin Y, Shen Q. The Autophagy Level Is Increased in the Synovial Tissues of Patients with Active Rheumatoid Arthritis and Is Correlated with Disease Severity. Mediators Inflamm. 2017;2017:7623145 pubmed publisher
Okerlund N, Schneider K, Leal Ortiz S, Montenegro Venegas C, Kim S, Garner L, et al. Bassoon Controls Presynaptic Autophagy through Atg5. Neuron. 2017;93:897-913.e7 pubmed publisher
Maus M, Cuk M, Patel B, Lian J, Ouimet M, Kaufmann U, et al. Store-Operated Ca2+ Entry Controls Induction of Lipolysis and the Transcriptional Reprogramming to Lipid Metabolism. Cell Metab. 2017;25:698-712 pubmed publisher
Gankam Kengne F, Couturier B, Soupart A, Brion J, Decaux G. Osmotic Stress-Induced Defective Glial Proteostasis Contributes to Brain Demyelination after Hyponatremia Treatment. J Am Soc Nephrol. 2017;28:1802-1813 pubmed publisher
Lee E, Wei Y, Zou Z, Tucker K, Rakheja D, Levine B, et al. Genetic inhibition of autophagy promotes p53 loss-of-heterozygosity and tumorigenesis. Oncotarget. 2016;7:67919-67933 pubmed publisher
Tan X, Wang H, Liang R, Chuang S. Human Rad23A plays a regulatory role in autophagy. Biochem Biophys Res Commun. 2016;478:1772-9 pubmed publisher
Xia X, Gao Y, Zhang J, Wang L, Zhao S, Che Y, et al. Autophagy mediated by arginine depletion activation of the nutrient sensor GCN2 contributes to interferon-?-induced malignant transformation of primary bovine mammary epithelial cells. Cell Death Discov. 2016;2:15065 pubmed publisher
Sousa C, Biancur D, Wang X, Halbrook C, Sherman M, Zhang L, et al. Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion. Nature. 2016;536:479-83 pubmed publisher
Choi M, Kim H, Ham M, Choi D, Lee T, Shin D. Amber Light (590 nm) Induces the Breakdown of Lipid Droplets through Autophagy-Related Lysosomal Degradation in Differentiated Adipocytes. Sci Rep. 2016;6:28476 pubmed publisher
Goodall M, Fitzwalter B, Zahedi S, Wu M, Rodriguez D, Mulcahy Levy J, et al. The Autophagy Machinery Controls Cell Death Switching between Apoptosis and Necroptosis. Dev Cell. 2016;37:337-349 pubmed publisher
Orhon I, Dupont N, Zaidan M, Boitez V, Burtin M, Schmitt A, et al. Primary-cilium-dependent autophagy controls epithelial cell volume in response to fluid flow. Nat Cell Biol. 2016;18:657-67 pubmed publisher
Sharifi M, Mowers E, Drake L, Collier C, Chen H, Zamora M, et al. Autophagy Promotes Focal Adhesion Disassembly and Cell Motility of Metastatic Tumor Cells through the Direct Interaction of Paxillin with LC3. Cell Rep. 2016;15:1660-72 pubmed publisher
Choudhury K, Bucha S, Baksi S, Mukhopadhyay D, Bhattacharyya N. Chaperone-like protein HYPK and its interacting partners augment autophagy. Eur J Cell Biol. 2016;95:182-94 pubmed publisher
Yun W, Kim E, Park J, Jo S, Bang S, Chang E, et al. Microtubule-associated protein light chain 3 is involved in melanogenesis via regulation of MITF expression in melanocytes. Sci Rep. 2016;6:19914 pubmed publisher
Imam S, Talley S, Nelson R, Dharan A, O CONNOR C, Hope T, et al. TRIM5α Degradation via Autophagy Is Not Required for Retroviral Restriction. J Virol. 2016;90:3400-10 pubmed publisher
Martínez López N, García Macia M, Sahu S, ATHONVARANGKUL D, Liebling E, Merlo P, et al. Autophagy in the CNS and Periphery Coordinate Lipophagy and Lipolysis in the Brown Adipose Tissue and Liver. Cell Metab. 2016;23:113-27 pubmed publisher
Sun Y, Chen K, Kwon C, Chen K. CK0403, a 9‑aminoacridine, is a potent anti‑cancer agent in human breast cancer cells. Mol Med Rep. 2016;13:933-8 pubmed publisher
Zhang F, Wang J, Chu J, Yang C, Xiao H, Zhao C, et al. MicroRNA-146a Induced by Hypoxia Promotes Chondrocyte Autophagy through Bcl-2. Cell Physiol Biochem. 2015;37:1442-53 pubmed publisher
Baisantry A, Bhayana S, Rong S, Ermeling E, Wrede C, Hegermann J, et al. Autophagy Induces Prosenescent Changes in Proximal Tubular S3 Segments. J Am Soc Nephrol. 2016;27:1609-16 pubmed publisher
Liu L, Li C, Lu Y, Zong X, Luo C, Sun J, et al. Baclofen mediates neuroprotection on hippocampal CA1 pyramidal cells through the regulation of autophagy under chronic cerebral hypoperfusion. Sci Rep. 2015;5:14474 pubmed publisher
Pal I, Parida S, Prashanth Kumar B, Banik P, Kumar Dey K, Chakraborty S, et al. Blockade of autophagy enhances proapoptotic potential of BI-69A11, a novel Akt inhibitor, in colon carcinoma. Eur J Pharmacol. 2015;765:217-27 pubmed publisher
Lee Y, Chen H, Su L, Chueh P. Sirtuin 1 (SIRT1) Deacetylase Activity and NAD⁺/NADH Ratio Are Imperative for Capsaicin-Mediated Programmed Cell Death. J Agric Food Chem. 2015;63:7361-70 pubmed publisher
Johansson I, Monsen V, Pettersen K, Mildenberger J, Misund K, Kaarniranta K, et al. The marine n-3 PUFA DHA evokes cytoprotection against oxidative stress and protein misfolding by inducing autophagy and NFE2L2 in human retinal pigment epithelial cells. Autophagy. 2015;11:1636-51 pubmed publisher
Dever S, Rodriguez M, Lapierre J, COSTIN B, El Hage N. Differing roles of autophagy in HIV-associated neurocognitive impairment and encephalitis with implications for morphine co-exposure. Front Microbiol. 2015;6:653 pubmed publisher
Pukaß K, Goldbaum O, Richter Landsberg C. Mitochondrial impairment and oxidative stress compromise autophagosomal degradation of α-synuclein in oligodendroglial cells. J Neurochem. 2015;135:194-205 pubmed publisher
Herpin A, Englberger E, Zehner M, Wacker R, Gessler M, Schartl M. Defective autophagy through epg5 mutation results in failure to reduce germ plasm and mitochondria. FASEB J. 2015;29:4145-61 pubmed publisher
Yang S, Long L, Li D, Zhang J, Jin S, Wang F, et al. β-Guanidinopropionic acid extends the lifespan of Drosophila melanogaster via an AMP-activated protein kinase-dependent increase in autophagy. Aging Cell. 2015;14:1024-33 pubmed publisher
Till A, Saito R, Merkurjev D, Liu J, Syed G, Kolnik M, et al. Evolutionary trends and functional anatomy of the human expanded autophagy network. Autophagy. 2015;11:1652-67 pubmed publisher
Yao J, Jia L, Khan N, Lin C, Mitter S, Boulton M, et al. Deletion of autophagy inducer RB1CC1 results in degeneration of the retinal pigment epithelium. Autophagy. 2015;11:939-53 pubmed publisher
Xin W, Zhao X, Liu L, Xu Y, Li Z, Chen L, et al. Acetyl-CoA carboxylase 2 suppression rescues human proximal tubular cells from palmitic acid induced lipotoxicity via autophagy. Biochem Biophys Res Commun. 2015;463:364-9 pubmed publisher
Kaushik S, Cuervo A. Degradation of lipid droplet-associated proteins by chaperone-mediated autophagy facilitates lipolysis. Nat Cell Biol. 2015;17:759-70 pubmed publisher
Kim Y, Kang Y, Lee N, Kim K, Hwang Y, Kim H, et al. Uvrag targeting by Mir125a and Mir351 modulates autophagy associated with Ewsr1 deficiency. Autophagy. 2015;11:796-811 pubmed publisher
Wu Q, Jiang D, Huang C, van Dyk L, Li L, Chu H. Trehalose-mediated autophagy impairs the anti-viral function of human primary airway epithelial cells. PLoS ONE. 2015;10:e0124524 pubmed publisher
Gonnella R, Granato M, Farina A, Santarelli R, Faggioni A, Cirone M. PKC theta and p38 MAPK activate the EBV lytic cycle through autophagy induction. Biochim Biophys Acta. 2015;1853:1586-95 pubmed publisher
Mohanty S, Jagannathan L, Ganguli G, Padhi A, Roy D, Alaridah N, et al. A mycobacterial phosphoribosyltransferase promotes bacillary survival by inhibiting oxidative stress and autophagy pathways in macrophages and zebrafish. J Biol Chem. 2015;290:13321-43 pubmed publisher
Sharifi M, Mowers E, Drake L, Macleod K. Measuring autophagy in stressed cells. Methods Mol Biol. 2015;1292:129-50 pubmed publisher
Roux C, Aligny C, Lesueur C, Girault V, Brunel V, Ramdani Y, et al. NMDA receptor blockade in the developing cortex induces autophagy-mediated death of immature cortical GABAergic interneurons: An ex vivo and in vivo study in Gad67-GFP mice. Exp Neurol. 2015;267:177-93 pubmed publisher
Prosser S, Morrison C. Centrin2 regulates CP110 removal in primary cilium formation. J Cell Biol. 2015;208:693-701 pubmed publisher
Caramés B, Olmer M, Kiosses W, Lotz M. The relationship of autophagy defects to cartilage damage during joint aging in a mouse model. Arthritis Rheumatol. 2015;67:1568-76 pubmed publisher
Reed M, Morris S, Owczarczyk A, Lukacs N. Deficiency of autophagy protein Map1-LC3b mediates IL-17-dependent lung pathology during respiratory viral infection via ER stress-associated IL-1. Mucosal Immunol. 2015;8:1118-30 pubmed publisher
Park E, Park M, Na H, Chung J. Xylitol induces cell death in lung cancer A549 cells by autophagy. Biotechnol Lett. 2015;37:983-90 pubmed publisher
Binotti B, Pavlos N, Riedel D, Wenzel D, Vorbrüggen G, Schalk A, et al. The GTPase Rab26 links synaptic vesicles to the autophagy pathway. elife. 2015;4:e05597 pubmed publisher
Lin H. In Vitro and in Vivo Atheroprotective Effects of Gossypetin against Endothelial Cell Injury by Induction of Autophagy. Chem Res Toxicol. 2015;28:202-15 pubmed
Malhotra R, Warne J, Salas E, Xu A, Debnath J. Loss of Atg12, but not Atg5, in pro-opiomelanocortin neurons exacerbates diet-induced obesity. Autophagy. 2015;11:145-54 pubmed publisher
Varga M, Fodor E, Vellai T. Autophagy in zebrafish. Methods. 2015;75:172-80 pubmed publisher
Sun K, Chen M, Tu M, Wang I, Chang S, Li C. MicroRNA-20a regulates autophagy related protein-ATG16L1 in hypoxia-induced osteoclast differentiation. Bone. 2015;73:145-53 pubmed publisher
Kraya A, Piao S, Xu X, Zhang G, Herlyn M, Gimotty P, et al. Identification of secreted proteins that reflect autophagy dynamics within tumor cells. Autophagy. 2015;11:60-74 pubmed publisher
El Hage N, Rodriguez M, Dever S, Masvekar R, Gewirtz D, Shacka J. HIV-1 and morphine regulation of autophagy in microglia: limited interactions in the context of HIV-1 infection and opioid abuse. J Virol. 2015;89:1024-35 pubmed publisher
Rožman S, Yousefi S, Oberson K, Kaufmann T, Benarafa C, Simon H. The generation of neutrophils in the bone marrow is controlled by autophagy. Cell Death Differ. 2015;22:445-56 pubmed publisher
product information
master code :
NB110-53818
SKU :
NB110-53818
product name :
ATG5 Antibody - BSA Free
unit size :
0.1 ml (also 0.025 ml)
description :
The ATG5 Antibody - BSA Free from Novus is a rabbit polyclonal antibody to ATG5. This antibody reacts with alligator,bovine,drosophila,drosophilia,fish,guinea pig,human,insect - drosophila,mouse,porcine,primate,rat,xenopus,zebrafish,fish - danio rerio (zebrafish). The ATG5 Antibody - BSA Free has been validated for the following applications: Immunohistochemistry,Western Blot,Immunocytochemistry/ Immunofluorescence,Simple Western,IF/IHC,ELISA,Flow Cytometry,Immunoprecipitation,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Radioimmunoassay,Proximity Ligation Assay,Electron Microscopy,Knockout Validated,Immunoblotting,Knockdown Validated.
target :
ATG5
category :
Primary Antibodies
buffer :
PBS
clonality :
Polyclonal
concentration :
1.0 mg/ml
conjugate :
Unconjugated
host :
Rabbit
immunogen :
This ATG5 Antibody was made to a synthetic peptide of an N-terminal region of the human ATG5 protein (within residues 1-50) [Swiss-Prot Q9H1Y0].
isotype :
IgG
purity :
Immunogen affinity purified
species :
Alligator,Bovine,Drosophila,Drosophilia,Fish,Guinea Pig,Human,Insect - Drosophila,Mouse,Porcine,Primate,Rat,Xenopus,Zebrafish,Fish - Danio rerio (Zebrafish)
specificity :
This is selective for the full-length and calpain cleaved isoform proteins
theoretical molecular weight :
32 kDa
gene symbol :
ATG5
Antibody validation :
Knockout/Knockdown
applications :
Immunohistochemistry,Western Blot,Immunocytochemistry/ Immunofluorescence,Simple Western,IF/IHC,ELISA,Flow Cytometry,Immunoprecipitation,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Radioimmunoassay,Proximity Ligation Assay,Electron Microscopy,Knockout Validated,Immunoblotting,Knockdown Validated
USD :
469 USD
alt names :
APG5, APG5 (Autophagy 5, S. Cerevisiae)-Like, APG5 autophagy 5-like (S. cerevisiae), APG5L, APG5-LIKE, ASP, ASPAPG5-LIKE, ATG5 Autophagy Related 5 Homolog, ATG5 autophagy related 5 homolog (S. cerevisiae), Autophagy protein 5, Autophagy Related 5, HAPG5, SCAR25
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.