product summary
request information :
company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
Rabbit Polyclonal PEDF R/PNPLA2/ATGL Antibody
catalog :
NB110-41536H
quantity :
0.1 ml
price :
309.00 USD
clonality :
polyclonal
host :
rabbit
conjugate :
HRP
reactivity :
human, mouse
application :
western blot
more info or order :
Novus Biologicals product webpage
product information
Catalog Number :
NB110-41536H
Product Name :
Rabbit Polyclonal PEDF R/PNPLA2/ATGL Antibody
List Price :
309.00 USD
Product Type :
Primary Antibodies
Package Size :
0.1 ml
AltNames :
Desnutrin, desnutrin, EC 3.1.1.3, FP17548, IPLA2-zeta, patatin-like phospholipase domain containing 2, patatin-like phospholipase domain-containing protein 2, patatin-like phospholipase domain-containing protein 2-like, PEDF-R, Pigment epithelium-derived factor, Transport-secretion protein 2, transport-secretion protein 2.2, triglyceride hydrolase, TTS2.2, TTS-2.2, TTS2DKFZp667M109, Adipose triglyceride lipase, ATGL1110001C14Rik, Calcium-independent phospholipase A2
Background :
Lipolytic enzymes are required for mobilization of fatty acids from triglyceride stores in adipose tissue. Energy homeostasis is affected by dysfunctional lipolysis and may contribute to the pathogenesis of obesity and insulin resistance. Until recently, hormone-sensitive lipase (HSL) was the only enzyme known to hydrolyze triglycerides in mammalian adipose tissue. It is now thought that a second enzyme, adipose triglyceride lipase (ATGL), catalyzes the initial step in triglyceride hydrolysis. ATGL is highly expressed in adipose tissue of mice and humans. It exhibits high substrate specificity for triacylglycerol and is associated with lipid droplets. Inhibition of ATGL markedly decreases total adipose acyl-hydrolase activity. Thus, ATGL and HSL coordinately catabolize stored triglycerides in adipose tissue of mammals.
Buffer :
PBS
Clonality :
Polyclonal
Conjugate :
HRP
Application Summary :
Western Blot
Host :
Rabbit
Immunogen :
A synthetic peptide within the C-terminal region (residues 400-500) of human ATGL. [Accession# NP_005171]
Localization :
Cytoplasm, Adiposomes
Preservative :
No Preservative
Purity :
Immunogen affinity purified
CrossReactivity :
Human and mouse.
Storage :
Store at 4C in the dark.
Swissprot Human :
Q96AD5
Uses :
This ATGL antibody is useful for Western Blot and Immunocytochemistry/Immunofluorescence. In ICC/IF, cytoplasmic/adiposomal staining was observed in HeLa cells.
Research Area :
Autophagy, Cancer, Lipid and Metabolism, Lipid Droplets, Signal Transduction
more info or order :
Novus Biologicals product webpage
company information
Novus Biologicals
8100 Southpark Way, A-8
Littleton, CO 80120
novus@novusbio.com
www.novusbio.com
3037301950
headquarters: USA
The mission of Novus Biologicals, LLC is to accelerate scientific discovery by developing and marketing unique products in the forefront of science. Novus Biologicals was organized to provide the biological research community with a mechanism for commercializing unique biological materials. We also focus on continually monitoring scientific trends and supply materials to serve these trends. By making these products widely available to institutional and commercial researchers, Novus Biologicals plays an important role in furthering biological research. All of Novus Biologicals products are supplied with detailed technical information and ongoing support. By serving niche and emerging markets, Novus Biologicals has become specialists in markets and has formed and will continue to form ongoing partnerships with our customers.