product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
CD11b/c Antibody - BSA Free
catalog :
NB110-40766
quantity :
0.1 ml (also 0.025 ml)
price :
409 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 60
Published Application/Species/Sample/DilutionReference
  • flow cytometry; rat; 1:100; loading ...; fig 1c
Ichinohe N, Ishii M, Tanimizu N, Mizuguchi T, Yoshioka Y, Ochiya T, et al. Extracellular vesicles containing miR-146a-5p secreted by bone marrow mesenchymal cells activate hepatocytic progenitors in regenerating rat livers. Stem Cell Res Ther. 2021;12:312 pubmed publisher
Garcia Hernandez M, Rangel Moreno J, García Castañeda M, Kenney H, Paine A, Thullen M, et al. Dendritic cell-specific transmembrane protein is required for synovitis and bone resorption in inflammatory arthritis. Front Immunol. 2022;13:1026574 pubmed publisher
Salman S, Meyers D, Wicks E, Lee S, Datan E, Thomas A, et al. HIF inhibitor 32-134D eradicates murine hepatocellular carcinoma in combination with anti-PD1 therapy. J Clin Invest. 2022;132: pubmed publisher
Pouso V xe1 zquez E, Bai X, Batall xe9 G, Roch G, Pol O. Effects of heme oxygenase 1 in the molecular changes and neuropathy associated with type 2 diabetes in mice. Biochem Pharmacol. 2022;199:114987 pubmed publisher
Liu J, Zhou L, Zhao F, Zhou C, Yang T, Xu Z, et al. Therapeutic effect of adipose stromal vascular fraction spheroids for partial bladder outlet obstruction induced underactive bladder. Stem Cell Res Ther. 2022;13:68 pubmed publisher
Li H, Xiao Y, Li Q, Yao J, Yuan X, Zhang Y, et al. The allergy mediator histamine confers resistance to immunotherapy in cancer patients via activation of the macrophage histamine receptor H1. Cancer Cell. 2022;40:36-52.e9 pubmed publisher
Liu X, Zheng H. Modulation of Sirt1 and FoxO1 on Hypothalamic Leptin-Mediated Sympathetic Activation and Inflammation in Diet-Induced Obese Rats. J Am Heart Assoc. 2021;10:e020667 pubmed publisher
Redondo A, Riego G, Pol O. The Antinociceptive, Antioxidant and Anti-Inflammatory Effects of 5-Fluoro-2-Oxindole during Inflammatory Pain. Antioxidants (Basel). 2020;9: pubmed publisher
Samanta D, Huang T, Shah R, Yang Y, Pan F, Semenza G. BIRC2 Expression Impairs Anti-Cancer Immunity and Immunotherapy Efficacy. Cell Rep. 2020;32:108073 pubmed publisher
Yamamoto Fukuda T, Akiyama N, Kojima H. L1CAM-ILK-YAP Mechanotransduction Drives Proliferative Activity of Epithelial Cells in Middle Ear Cholesteatoma. Am J Pathol. 2020;: pubmed publisher
Meng C, Tian G, Xu C, Li X, Zhang Y, Wang Y, et al. Hippo kinases MST1 and MST2 control the differentiation of the epididymal initial segment via the MEK-ERK pathway. Cell Death Differ. 2020;: pubmed publisher
Lemons K, Fu Z, Ogura T, Lin W. TRPM5-expressing Microvillous Cells Regulate Region-specific Cell Proliferation and Apoptosis During Chemical Exposure. Neuroscience. 2020;434:171-190 pubmed publisher
Tsai M, Huang C, Wei Y, Liu T, Lin M, Yi L, et al. Combined Chibby and β-Catenin Predicts Clinical Outcomes in Patients with Hepatocellular Carcinoma. Int J Mol Sci. 2020;21: pubmed publisher
Chou P, Lin Y, Wu S, Lin S, Srinivasan P, Hsieh D, et al. Supercritical Carbon Dioxide-decellularized Porcine Acellular Dermal Matrix combined with Autologous Adipose-derived Stem Cells: Its Role in Accelerated Diabetic Wound Healing. Int J Med Sci. 2020;17:354-367 pubmed publisher
Kim Y, Tsang T, Anderson G, Posimo J, Brady D. Inhibition of BCL2 Family Members Increases the Efficacy of Copper Chelation in BRAFV600E-Driven Melanoma. Cancer Res. 2020;80:1387-1400 pubmed publisher
Alvarez Carbonell D, Ye F, Ramanath N, Garcia Mesa Y, Knapp P, Hauser K, et al. Cross-talk between microglia and neurons regulates HIV latency. PLoS Pathog. 2019;15:e1008249 pubmed publisher
Li Q, Liu B, Chao H, Ji Y, Lu Y, Mehmood R, et al. LRIG1 is a pleiotropic androgen receptor-regulated feedback tumor suppressor in prostate cancer. Nat Commun. 2019;10:5494 pubmed publisher
Díaz A, Polo S, Gallardo N, Leánez S, Pol O. Analgesic and Antidepressant Effects of Oltipraz on Neuropathic Pain in Mice by Modulating Microglial Activation. J Clin Med. 2019;8: pubmed publisher
Li H, Yu Y, Zhao Y, Wu D, Yu X, Lu J, et al. Small molecule inhibitor agerafenib effectively suppresses neuroblastoma tumor growth in mouse models via inhibiting ERK MAPK signaling. Cancer Lett. 2019;: pubmed publisher
Moreno P, Cazuza R, Mendes Gomes J, Díaz A, Polo S, Leánez S, et al. The Effects of Cobalt Protoporphyrin IX and Tricarbonyldichlororuthenium (II) Dimer Treatments and Its Interaction with Nitric Oxide in the Locus Coeruleus of Mice with Peripheral Inflammation. Int J Mol Sci. 2019;20: pubmed publisher
Gunin A, Golubtsova N, Kravtsova O, Subbotkin A, Subbotkina N, Filippov F. Number, Proliferative Activity, and Expression of Thyroid Hormone Receptors in Dermal Fibroblasts in Mice with Changed Thyroid Status. Bull Exp Biol Med. 2019;166:797-801 pubmed publisher
Li S, Song Y, Quach C, Guo H, Jang G, Maazi H, et al. Transcriptional regulation of autophagy-lysosomal function in BRAF-driven melanoma progression and chemoresistance. Nat Commun. 2019;10:1693 pubmed publisher
Amano H, Chaudhury A, Rodriguez Aguayo C, Lu L, Akhanov V, Catic A, et al. Telomere Dysfunction Induces Sirtuin Repression that Drives Telomere-Dependent Disease. Cell Metab. 2019;29:1274-1290.e9 pubmed publisher
Xu J, Song J, Yang X, Guo J, Wang T, Zhuo W. ProNGF siRNA inhibits cell proliferation and invasion of pancreatic cancer cells and promotes anoikis. Biomed Pharmacother. 2019;111:1066-1073 pubmed publisher
Naito H, Iba T, Wakabayashi T, Tai Nagara I, Suehiro J, Jia W, et al. TAK1 Prevents Endothelial Apoptosis and Maintains Vascular Integrity. Dev Cell. 2019;48:151-166.e7 pubmed publisher
Gunin A, Golubtsova N, Subbotkina N, Subbotkin A. [The influence of metformin on age-related changes in the number and proliferation of dermal fibroblasts in mice.]. Adv Gerontol. 2018;31:505-509 pubmed
Ferreira Chamorro P, Redondo A, Riego G, Leánez S, Pol O. Sulforaphane Inhibited the Nociceptive Responses, Anxiety- and Depressive-Like Behaviors Associated With Neuropathic Pain and Improved the Anti-allodynic Effects of Morphine in Mice. Front Pharmacol. 2018;9:1332 pubmed publisher
Stojiljkovic M, Ain Q, Bondeva T, Heller R, Schmeer C, Witte O. Phenotypic and functional differences between senescent and aged murine microglia. Neurobiol Aging. 2019;74:56-69 pubmed publisher
Kumari A, Yokota Y, Li L, Bradley R, Mistretta C. Species generalization and differences in Hedgehog pathway regulation of fungiform and circumvallate papilla taste function and somatosensation demonstrated with sonidegib. Sci Rep. 2018;8:16150 pubmed publisher
Gopalakrishnan K, Teitelbaum S, Wetmur J, Manservisi F, Falcioni L, Panzacchi S, et al. Histology and Transcriptome Profiles of the Mammary Gland across Critical Windows of Development in Sprague Dawley Rats. J Mammary Gland Biol Neoplasia. 2018;23:149-163 pubmed publisher
Cruz V, Arner E, Wynne K, Scherer P, Brekken R. Loss of Tbk1 kinase activity protects mice from diet-induced metabolic dysfunction. Mol Metab. 2018;16:139-149 pubmed publisher
Anurag M, Punturi N, Hoog J, Bainbridge M, Ellis M, Haricharan S. Comprehensive Profiling of DNA Repair Defects in Breast Cancer Identifies a Novel Class of Endocrine Therapy Resistance Drivers. Clin Cancer Res. 2018;24:4887-4899 pubmed publisher
Duteil D, Tourrette Y, Eberlin A, Willmann D, Patel D, Friedrichs N, et al. The histone acetyltransferase inhibitor Nir regulates epidermis development. Development. 2018;145: pubmed publisher
Lu N, Li Y, Zhang Z, Xing J, Sun Y, Yao S, et al. Human Semaphorin-4A drives Th2 responses by binding to receptor ILT-4. Nat Commun. 2018;9:742 pubmed publisher
Tachikawa S, Shimizu M, Maruyama K, Ohnuma K. Thalidomide induces apoptosis during early mesodermal differentiation of human induced pluripotent stem cells. In Vitro Cell Dev Biol Anim. 2018;54:231-240 pubmed publisher
Riego G, Redondo A, Leánez S, Pol O. Mechanism implicated in the anti-allodynic and anti-hyperalgesic effects induced by the activation of heme oxygenase 1/carbon monoxide signaling pathway in the central nervous system of mice with neuropathic pain. Biochem Pharmacol. 2018;148:52-63 pubmed publisher
Kumari P, Saha I, Narayanan A, Narayanan S, Takaoka A, Kumar N, et al. Essential role of HCMV deubiquitinase in promoting oncogenesis by targeting anti-viral innate immune signaling pathways. Cell Death Dis. 2017;8:e3078 pubmed publisher
Yamakami Y, Kohashi K, Oyama K, Mohri Y, Hidema S, Nishimori K. LGR4 is required for sequential molar development. Biochem Biophys Rep. 2016;8:174-183 pubmed publisher
Pavlidou T, Rosina M, Fuoco C, Gerini G, Gargioli C, Castagnoli L, et al. Regulation of myoblast differentiation by metabolic perturbations induced by metformin. PLoS ONE. 2017;12:e0182475 pubmed publisher
Fishbein I, Guerrero D, Alferiev I, Foster J, Minutolo N, Chorny M, et al. Stent-based delivery of adeno-associated viral vectors with sustained vascular transduction and iNOS-mediated inhibition of in-stent restenosis. Gene Ther. 2017;24:717-726 pubmed publisher
Furukawa S, Nagaike M, Ozaki K. Databases for technical aspects of immunohistochemistry. J Toxicol Pathol. 2017;30:79-107 pubmed publisher
Ding Z, Xu W, Zhang J, Zou W, Guo Q, Huang C, et al. Normalizing GDNF expression in the spinal cord alleviates cutaneous hyperalgesia but not ongoing pain in a rat model of bone cancer pain. Int J Cancer. 2017;140:411-422 pubmed publisher
Kalliokoski S, Piqueras V, Frías R, Sulic A, Määttä J, Kähkönen N, et al. Transglutaminase 2-specific coeliac disease autoantibodies induce morphological changes and signs of inflammation in the small-bowel mucosa of mice. Amino Acids. 2017;49:529-540 pubmed publisher
Liang X, Luo M, Wei X, Ma C, Yang Y, Shao B, et al. A folate receptor-targeted lipoplex delivering interleukin-15 gene for colon cancer immunotherapy. Oncotarget. 2016;7:52207-52217 pubmed publisher
Yancu D, Blouin M, Birman E, Florianova L, Aleynikova O, Zakikhani M, et al. A phenotype of IGFBP-3 knockout mice revealed by dextran sulfate-induced colitis. J Gastroenterol Hepatol. 2017;32:146-153 pubmed publisher
Kai T, Tsukamoto Y, Hijiya N, Tokunaga A, Nakada C, Uchida T, et al. Kidney-specific knockout of Sav1 in the mouse promotes hyperproliferation of renal tubular epithelium through suppression of the Hippo pathway. J Pathol. 2016;239:97-108 pubmed publisher
Chen N, Chyau C, Lee Y, Tseng H, Chou F. Promotion of mitotic catastrophe via activation of PTEN by paclitaxel with supplement of mulberry water extract in bladder cancer cells. Sci Rep. 2016;6:20417 pubmed publisher
Castany S, Carcolé M, Leánez S, Pol O. The Induction of Heme Oxygenase 1 Decreases Painful Diabetic Neuropathy and Enhances the Antinociceptive Effects of Morphine in Diabetic Mice. PLoS ONE. 2016;11:e0146427 pubmed publisher
Biktasova A, Dudimah D, Uzhachenko R, Park K, Akhter A, Arasada R, et al. Multivalent Forms of the Notch Ligand DLL-1 Enhance Antitumor T-cell Immunity in Lung Cancer and Improve Efficacy of EGFR-Targeted Therapy. Cancer Res. 2015;75:4728-41 pubmed publisher
Velarde M, Demaria M, Melov S, Campisi J. Pleiotropic age-dependent effects of mitochondrial dysfunction on epidermal stem cells. Proc Natl Acad Sci U S A. 2015;112:10407-12 pubmed publisher
Massó Vallés D, Jauset T, Serrano E, Sodir N, Pedersen K, Affara N, et al. Ibrutinib exerts potent antifibrotic and antitumor activities in mouse models of pancreatic adenocarcinoma. Cancer Res. 2015;75:1675-81 pubmed publisher
Nowak D, Cho H, Herzka T, Watrud K, DeMarco D, Wang V, et al. MYC Drives Pten/Trp53-Deficient Proliferation and Metastasis due to IL6 Secretion and AKT Suppression via PHLPP2. Cancer Discov. 2015;5:636-51 pubmed publisher
Aggarwal A, Höbaus J, Tennakoon S, Prinz Wohlgenannt M, Graça J, Price S, et al. Active vitamin D potentiates the anti-neoplastic effects of calcium in the colon: A cross talk through the calcium-sensing receptor. J Steroid Biochem Mol Biol. 2016;155:231-8 pubmed publisher
Franz H, Greschik H, Willmann D, Ozretić L, Jilg C, Wardelmann E, et al. The histone code reader SPIN1 controls RET signaling in liposarcoma. Oncotarget. 2015;6:4773-89 pubmed
Lindley L, Curtis K, Sánchez Mejías A, Rieger M, Robbins D, Briegel K. The WNT-controlled transcriptional regulator LBH is required for mammary stem cell expansion and maintenance of the basal lineage. Development. 2015;142:893-904 pubmed publisher
Zhou Y, Rychahou P, Wang Q, Weiss H, Evers B. TSC2/mTORC1 signaling controls Paneth and goblet cell differentiation in the intestinal epithelium. Cell Death Dis. 2015;6:e1631 pubmed publisher
Jin D, Yang J, Hu J, Wang L, Zuo J. MCP-1 stimulates spinal microglia via PI3K/Akt pathway in bone cancer pain. Brain Res. 2015;1599:158-67 pubmed publisher
Rachidi S, Sun S, Wu B, Jones E, Drake R, Ogretmen B, et al. Endoplasmic reticulum heat shock protein gp96 maintains liver homeostasis and promotes hepatocellular carcinogenesis. J Hepatol. 2015;62:879-88 pubmed publisher
Mathes A, Rice L, Affandi A, Dimarzio M, Rifkin I, Stifano G, et al. CpGB DNA activates dermal macrophages and specifically recruits inflammatory monocytes into the skin. Exp Dermatol. 2015;24:133-9 pubmed publisher
Beristain A, Molyneux S, Joshi P, Pomroy N, Di Grappa M, Chang M, et al. PKA signaling drives mammary tumorigenesis through Src. Oncogene. 2015;34:1160-73 pubmed publisher
product information
master code :
NB110-40766
SKU :
NB110-40766
product name :
CD11b/c Antibody - BSA Free
unit size :
0.1 ml (also 0.025 ml)
description :
The CD11b/c Antibody - BSA Free from Novus is a rabbit polyclonal antibody to CD11b/c. This antibody reacts with human,mouse,rat. The CD11b/c Antibody - BSA Free has been validated for the following applications: Immunohistochemistry,Immunocytochemistry/ Immunofluorescence,IF/IHC,Flow Cytometry,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen.
target :
CD11b/c
category :
Primary Antibodies
buffer :
PBS, 30% Glycerol
clonality :
Polyclonal
concentration :
1.0 mg/ml
conjugate :
Unconjugated
host :
Rabbit
immunogen :
A synthetic peptide made to an internal region (within residues 500-600) of the mouse CD11 (b/c) protein. [Swiss-Prot: P05555]
isotype :
IgG
purity :
Immunogen affinity purified
species :
Human,Mouse,Rat
theoretical molecular weight :
160 kDa
gene symbol :
ITGAM
Antibody validation :
Biological Validation
applications :
Immunohistochemistry,Immunocytochemistry/ Immunofluorescence,IF/IHC,Flow Cytometry,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen
USD :
409 USD
alt names :
antigen CD11b (p170), CD11 antigen-like family member B, CD11b, CD11b antigen, CD11Bintegrin, alpha M (complement component receptor 3, alpha; also known as CD11b(p170), macrophage antigen alpha polypeptide), Cell surface glycoprotein MAC-1 subunit alpha, CR-3 alpha chain, CR3AMGC117044, integrin alpha-M, integrin, alpha M (complement component 3 receptor 3 subunit), Leukocyte adhesion receptor MO1, MAC-1, MAC1A, macrophage antigen alpha polypeptide, MO1A, Neutrophil adherence receptor, neutrophil adherence receptor alpha-M subunit, SLEB6
storage :
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.