product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
SOX2 Antibody - BSA Free
catalog :
NB110-37235
quantity :
0.1 ml (also 0.025 ml)
price :
429 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
1251A
reactivity :
human, mouse, rat, dogs
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section
more info or order :
citations: 35
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; mouse; fig 3l
Duan S, Sawyer T, Sontz R, Wieland B, Diaz A, Merchant J. GFAP-directed Inactivation of Men1 Exploits Glial Cell Plasticity in Favor of Neuroendocrine Reprogramming. Cell Mol Gastroenterol Hepatol. 2022;14:1025-1051 pubmed publisher
Wei Q, Liu Z, Zhu J, Jiang W, Xie H, Feng G, et al. The Ubiquitin E3 Ligase FBXO33 Suppresses Stem Cell-Like Properties and Metastasis in Non-Small-Cell Lung Cancer by Promoting Ubiquitination and Degradation of Myc. Front Biosci (Landmark Ed). 2024;29:296 pubmed publisher
Siu W, Ma H, Ko C, Shiu H, Cheng W, Lee Y, et al. Rat Plantar Fascia Stem/Progenitor Cells Showed Lower Expression of Ligament Markers and Higher Pro-Inflammatory Cytokines after Intensive Mechanical Loading or Interleukin-1β Treatment In Vitro. Cells. 2023;12: pubmed publisher
Kim J, Cho S, Youn D, Hong E, Park C, Lee Y, et al. Therapeutic effect of a hydrogel-based neural stem cell delivery sheet for mild traumatic brain injury. Acta Biomater. 2023;167:335-347 pubmed publisher
Erda x11f E, Emekli A, G xfc nd xfc z T, K xfc xe7 xfc kali C, K xfc rt xfc nc xfc M, T xfc z xfc n E. Serum IgG of patients with relapsing inflammatory optic neuropathy immunoreacts with Sox2-positive glial cells of the optic nerve. Mult Scler Relat Disord. 2023;73:104694 pubmed publisher
Filidou E, Kandilogiannakis L, Tarapatzi G, Spathakis M, Su C, Rai A, et al. A Simplified and Effective Approach for the Isolation of Small Pluripotent Stem Cells Derived from Human Peripheral Blood. Biomedicines. 2023;11: pubmed publisher
Huan Y, Wu X, Chen T, Dou Y, Jia B, He X, et al. Necroptosis plays a crucial role in the exacerbation of retinal injury after blunt ocular trauma. Neural Regen Res. 2023;18:922-928 pubmed publisher
Yang Y, Chen C, Zuo Q, Lu H, Salman S, Lyu Y, et al. NARF is a hypoxia-induced coactivator for OCT4-mediated breast cancer stem cell specification. Sci Adv. 2022;8:eabo5000 pubmed publisher
Cesare E, Urciuolo A, Stuart H, Torchio E, Gesualdo A, Laterza C, et al. 3D ECM-rich environment sustains the identity of naive human iPSCs. Cell Stem Cell. 2022;29:1703-1717.e7 pubmed publisher
Zhigalina D, Malakhova A, Vasilyeva O, Grigor eva E, Sivtsev A, Kolesnikov N, et al. Generation of an induced pluripotent stem cell line ICGi030-A from a Wilson's disease patient carrying a frameshift mutation p.Lys1013fs and missense mutation p.H1069Q in the ATP7B gene. Stem Cell Res. 2021;57:102556 pubmed publisher
Lu H, Lyu Y, Tran L, Lan J, Xie Y, Yang Y, et al. HIF-1 recruits NANOG as a coactivator for TERT gene transcription in hypoxic breast cancer stem cells. Cell Rep. 2021;36:109757 pubmed publisher
Peskova L, Jurcikova D, Vanova T, Krivanek J, Capandova M, Srámková Z, et al. miR-183/96/182 cluster is an important morphogenetic factor targeting PAX6 expression in differentiating human retinal organoids. Stem Cells. 2020;: pubmed publisher
Wang H, Dou S, Zhu J, Shao Z, Wang C, Cheng B. Ghrelin protects dopaminergic neurons against MPTP neurotoxicity through promoting autophagy and inhibiting endoplasmic reticulum mediated apoptosis. Brain Res. 2020;1746:147023 pubmed publisher
Lovnicki J, Gan Y, Feng T, Li Y, Xie N, Ho C, et al. LIN28B promotes the development of neuroendocrine prostate cancer. J Clin Invest. 2020;130:5338-5348 pubmed publisher
Butler M, Chotiwan N, Brewster C, DiLisio J, Ackart D, Podell B, et al. Cyclin-Dependent Kinases 8 and 19 Regulate Host Cell Metabolism during Dengue Virus Serotype 2 Infection. Viruses. 2020;12: pubmed publisher
Lu H, Xie Y, Tran L, Lan J, Yang Y, Murugan N, et al. Chemotherapy-induced S100A10 recruits KDM6A to facilitate OCT4-mediated breast cancer stemness. J Clin Invest. 2020;: pubmed publisher
Wang J, Lee C, Deci M, Jasiewicz N, Verma A, Canty J, et al. MiR-101a loaded extracellular nanovesicles as bioactive carriers for cardiac repair. Nanomedicine. 2020;27:102201 pubmed publisher
Chien H, Ying T, Hsieh S, Lin C, Yu Y, Kao S, et al. α-Mangostin attenuates stemness and enhances cisplatin-induced cell death in cervical cancer stem-like cells through induction of mitochondrial-mediated apoptosis. J Cell Physiol. 2020;235:5590-5601 pubmed publisher
Cornax I, Pluhar G, Clark H, O Sullivan M. Oligodendroglioma with Neuronal Differentiation in Two Boxer Dogs. J Comp Pathol. 2019;172:11-16 pubmed publisher
Martinez Legaspi S, Segatori L. Aggregation Behavior of Nanoparticle-Peptide Systems Affects Autophagy. Bioconjug Chem. 2019;30:1986-1997 pubmed publisher
Gagliano O, Luni C, Qin W, Bertin E, Torchio E, Galvanin S, et al. Microfluidic reprogramming to pluripotency of human somatic cells. Nat Protoc. 2019;14:722-737 pubmed publisher
Dun X, Carr L, Woodley P, Barry R, Drake L, Mindos T, et al. Macrophage-Derived Slit3 Controls Cell Migration and Axon Pathfinding in the Peripheral Nerve Bridge. Cell Rep. 2019;26:1458-1472.e4 pubmed publisher
Wang J, Xu S, Duan J, Yi L, Guo Y, Shi Y, et al. Invasion of white matter tracts by glioma stem cells is regulated by a NOTCH1-SOX2 positive-feedback loop. Nat Neurosci. 2019;22:91-105 pubmed publisher
Saijo A, Goto H, Nakano M, Mitsuhashi A, Aono Y, Hanibuchi M, et al. Bone marrow-derived fibrocytes promote stem cell-like properties of lung cancer cells. Cancer Lett. 2018;421:17-27 pubmed publisher
Roberts S, Dun X, Doddrell R, Mindos T, Drake L, Onaitis M, et al. Sox2 expression in Schwann cells inhibits myelination in vivo and induces influx of macrophages to the nerve. Development. 2017;144:3114-3125 pubmed publisher
Lu H, Chen I, Shimoda L, Park Y, Zhang C, Tran L, et al. Chemotherapy-Induced Ca2+ Release Stimulates Breast Cancer Stem Cell Enrichment. Cell Rep. 2017;18:1946-1957 pubmed publisher
Verwey M, Nolte E, Joubert A, Theron A. Autophagy induced by a sulphamoylated estrone analogue contributes to its cytotoxic effect on breast cancer cells. Cancer Cell Int. 2016;16:91 pubmed
Alić I, Kosi N, Kapuralin K, Gorup D, Gajovic S, Pochet R, et al. Neural stem cells from mouse strain Thy1 YFP-16 are a valuable tool to monitor and evaluate neuronal differentiation and morphology. Neurosci Lett. 2016;634:32-41 pubmed publisher
Zhang C, Zhi W, Lu H, Samanta D, Chen I, Gabrielson E, et al. Hypoxia-inducible factors regulate pluripotency factor expression by ZNF217- and ALKBH5-mediated modulation of RNA methylation in breast cancer cells. Oncotarget. 2016;7:64527-64542 pubmed publisher
Wechman S, Rao X, Cheng P, Gomez Gutierrez J, McMasters K, Zhou H. Development of an Oncolytic Adenovirus with Enhanced Spread Ability through Repeated UV Irradiation and Cancer Selection. Viruses. 2016;8: pubmed publisher
Liu L, Liu C, Zhang Q, Shen J, Zhang H, Shan J, et al. SIRT1-mediated transcriptional regulation of SOX2 is important for self-renewal of liver cancer stem cells. Hepatology. 2016;64:814-27 pubmed publisher
Luni C, Giulitti S, Serena E, Ferrari L, Zambon A, Gagliano O, et al. High-efficiency cellular reprogramming with microfluidics. Nat Methods. 2016;13:446-52 pubmed publisher
Rad A, Farshchian M, Forghanifard M, Matin M, Bahrami A, Geerts D, et al. Predicting the molecular role of MEIS1 in esophageal squamous cell carcinoma. Tumour Biol. 2016;37:1715-25 pubmed publisher
Lu H, Samanta D, Xiang L, Zhang H, Hu H, Chen I, et al. Chemotherapy triggers HIF-1-dependent glutathione synthesis and copper chelation that induces the breast cancer stem cell phenotype. Proc Natl Acad Sci U S A. 2015;112:E4600-9 pubmed publisher
Lee Y, Yu C, Lan C, Lee C, Lee H, Kuo Y, et al. Plasminogen activator inhibitor-1 as regulator of tumor-initiating cell properties in head and neck cancers. Head Neck. 2016;38 Suppl 1:E895-904 pubmed publisher
product information
master code :
NB110-37235
SKU :
NB110-37235
product name :
SOX2 Antibody - BSA Free
unit size :
0.1 ml (also 0.025 ml)
description :
The SOX2 Antibody - BSA Free from Novus is a rabbit polyclonal antibody to SOX2. This antibody reacts with canine,human,mouse,rat,sheep. The SOX2 Antibody - BSA Free has been validated for the following applications: Immunohistochemistry,Immunocytochemistry/ Immunofluorescence,IF/IHC,Western Blot,Immunohistochemistry-Paraffin,Immunocytochemistry,Knockdown Validated,Flow Cytometry,Flow (Intracellular).
target :
SOX2
category :
Primary Antibodies
buffer :
PBS
clonality :
Polyclonal
concentration :
1.0 mg/ml
conjugate :
Unconjugated
host :
Rabbit
immunogen :
A synthetic peptide made to the N-terminal region of human SOX2 protein (within residues 1-100). [Swiss-Prot# P48431]
isotype :
IgG
purity :
Immunogen affinity purified
species :
Canine,Human,Mouse,Rat,Sheep
gene symbol :
SOX2
accessionNumbers :
P48431
applications :
Immunocytochemistry/ Immunofluorescence,IF/IHC,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunocytochemistry,Knockdown Validated,Flow Cytometry,Flow (Intracellular)
USD :
429 USD
alt names :
ANOP3, MCOPS3, MGC2413, SRY (sex determining region Y)-box 2, SRY-related HMG-box gene 2, transcription factor SOX2, transcription factor SOX-2
storage :
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.