product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
Lysine (K)-specific Demethylase 5B/KDM5B/JARID1B Antibody - BSA Free
catalog :
NB100-97821
quantity :
100 ul
price :
459 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section
more info or order :
Novus Biologicals product webpage
citations: 13
Reference
Smith T, White T, Chen Z, Stewart L. The KDM5 inhibitor PBIT reduces proliferation of castration-resistant prostate cancer cells via cell cycle arrest and the induction of senescence. Exp Cell Res. 2024;437:113991 pubmed publisher
Ullrich V, Ertmer S, Baginska A, Dorsch M, Gull H, Cima I, et al. KDM5B predicts temozolomide-resistant subclones in glioblastoma. iScience. 2024;27:108596 pubmed publisher
Chauvistr xe9 H, Shannan B, Daignault Mill S, Ju R, Picard D, Egetemaier S, et al. Persister state-directed transitioning and vulnerability in melanoma. Nat Commun. 2022;13:3055 pubmed publisher
Zhang S, Cai W, Liu X, Thakral D, Luo J, Chan L, et al. KDM5B promotes immune evasion by recruiting SETDB1 to silence retroelements. Nature. 2021;598:682-687 pubmed publisher
Li G, Kanagasabai T, Lu W, Zou M, Zhang S, Celada S, et al. KDM5B Is Essential for the Hyperactivation of PI3K/AKT Signaling in Prostate Tumorigenesis. Cancer Res. 2020;80:4633-4643 pubmed publisher
Coste Pradas J, Auguste G, Matkovich S, Lombardi R, Chen S, Garnett T, et al. Identification of Genes and Pathways Regulated by Lamin A in Heart. J Am Heart Assoc. 2020;9:e015690 pubmed publisher
Webster M, Fane M, Alicea G, Basu S, Kossenkov A, Marino G, et al. Paradoxical Role for Wild-Type p53 in Driving Therapy Resistance in Melanoma. Mol Cell. 2020;77:633-644.e5 pubmed publisher
Vogel F, Bordag N, Zügner E, Trajkovic Arsic M, Chauvistré H, Shannan B, et al. Targeting the H3K4 demethylase KDM5B reprograms the metabolome and phenotype of melanoma cells. J Invest Dermatol. 2019;: pubmed publisher
Shannan B, Matschke J, Chauvistré H, Vogel F, Klein D, Meier F, et al. Sequence-dependent cross-resistance of combined radiotherapy plus BRAFV600E inhibition in melanoma. Eur J Cancer. 2019;109:137-153 pubmed publisher
Hayashi K, Tasaka T, Kondo T, Ishikawa Y, Goto M, Matsuhashi Y, et al. Successful Cord Blood Transplantation in a Werner Syndrome Patient with High-risk Myelodysplastic Syndrome. Intern Med. 2019;58:109-113 pubmed publisher
Boyle S, Fedele C, Corbin V, Wybacz E, Szeto P, Lewin J, et al. CD271 Expression on Patient Melanoma Cells Is Unstable and Unlinked to Tumorigenicity. Cancer Res. 2016;76:3965-77 pubmed publisher
Thangavel S, Berti M, Levikova M, Pinto C, Gomathinayagam S, Vujanovic M, et al. DNA2 drives processing and restart of reversed replication forks in human cells. J Cell Biol. 2015;208:545-62 pubmed publisher
Lu W, Liu S, Li B, Xie Y, Adhiambo C, Yang Q, et al. SKP2 inactivation suppresses prostate tumorigenesis by mediating JARID1B ubiquitination. Oncotarget. 2015;6:771-88 pubmed
product information
master code :
NB100-97821
SKU :
NB100-97821
product name :
Lysine (K)-specific Demethylase 5B/KDM5B/JARID1B Antibody - BSA Free
unit size :
100 ul
description :
The Lysine (K)-specific Demethylase 5B/KDM5B/JARID1B Antibody - BSA Free from Novus is a rabbit polyclonal antibody to Lysine (K)-specific Demethylase 5B/KDM5B/JARID1B. This antibody reacts with human. The Lysine (K)-specific Demethylase 5B/KDM5B/JARID1B Antibody - BSA Free has been validated for the following applications: Western Blot,Chemotaxis,IF/IHC,Flow Cytometry,Immunoprecipitation,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry,Immunohistochemistry-Paraffin.
target :
Lysine (K)-specific Demethylase 5B/KDM5B/JARID1B
category :
Primary Antibodies
buffer :
Tris-Citrate/Phosphate (pH 7.0 - 8.0)
clonality :
Polyclonal
concentration :
1.0 mg/ml
conjugate :
Unconjugated
host :
Rabbit
immunogen :
The immunogen recognized by this antibody maps to a region between residue 1494 and 1544 of human Jumonji, AT rich interactive domain 1B (NP_006609.3).
isotype :
IgG
purity :
Immunogen affinity purified
species :
Human
gene symbol :
KDM5B
accessionNumbers :
Q9UGL1
applications :
Chemotaxis,IF/IHC,Flow Cytometry,Immunoprecipitation,Western Blot,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry,Immunohistochemistry-Paraffin
USD :
459 USD
alt names :
CT31FLJ10538, EC 1.14.11, EC 1.14.11.-, homolog 1A, JARID1BFLJ16281, jumonji, AT rich interactive domain 1B, Jumonji, AT rich interactive domain 1B (RBP2-like), lysine (K)-specific demethylase 5B, PLU-1FLJ12459, PLU1FLJ23670, PUT1, RBBP2H1, RBBP2H1AFLJ12491, RBP2-H1, Retinoblastoma-binding protein 2 homolog 1
storage :
Store at 4C. Do not freeze.
more info or order :
Novus Biologicals product webpage
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.