product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
CEP290 Antibody
catalog :
NB100-86991
quantity :
100 ul
price :
459 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunocytochemistry, immunoprecipitation
more info or order :
citations: 5
Reference
Speight P, Rozycki M, Venugopal S, Szaszi K, Kofler M, Kapus A. Myocardin-related transcription factor and serum response factor regulate cilium turnover by both transcriptional and local mechanisms. iScience. 2021;24:102739 pubmed publisher
Corral Serrano J, Lamers I, van Reeuwijk J, Duijkers L, Hoogendoorn A, Yildirim A, et al. PCARE and WASF3 regulate ciliary F-actin assembly that is required for the initiation of photoreceptor outer segment disk formation. Proc Natl Acad Sci U S A. 2020;117:9922-9931 pubmed publisher
Dulla K, Aguilà M, Lane A, Jovanovic K, Parfitt D, Schulkens I, et al. Splice-Modulating Oligonucleotide QR-110 Restores CEP290 mRNA and Function in Human c.2991+1655A>G LCA10 Models. Mol Ther Nucleic Acids. 2018;12:730-740 pubmed publisher
Barny I, Perrault I, Michel C, Soussan M, Goudin N, Rio M, et al. Basal exon skipping and nonsense-associated altered splicing allows bypassing complete CEP290 loss-of-function in individuals with unusually mild retinal disease. Hum Mol Genet. 2018;: pubmed publisher
Kurtenbach S, Gießl A, Strömberg S, Kremers J, Atorf J, Rasche S, et al. The BEACH Protein LRBA Promotes the Localization of the Heterotrimeric G-protein Golf to Olfactory Cilia. Sci Rep. 2017;7:8409 pubmed publisher
product information
brand :
Novus
master code :
NB100-86991
SKU :
NB100-86991
product name :
CEP290 Antibody
unit size :
100 ul
seo description :
The CEP290 Antibody - BSA Free from Novus is a rabbit polyclonal antibody to CEP290. This antibody reacts with human,mouse. The CEP290 Antibody - BSA Free has been validated for the following applications: Western Blot,Immunocytochemistry/ Immunofluorescence,Immunoprecipitation.
target :
CEP290
category :
Primary Antibodies
buffer :
Tris-Citrate/Phosphate (pH 7.0 - 8.0)
clonality :
Polyclonal
concentration :
1.0 mg/ml
conjugate :
Unconjugated
dilution :
Western Blot 1:2000-1:10000, Immunocytochemistry/ Immunofluorescence 1:250-1:1000, Immunoprecipitation 2-5 ug/mg lysate
host :
Rabbit
immunogen :
The immunogen recognized by this antibody maps to a region between residue 2429 and 2479 of human centrosomal protein 290kDa using the numbering given in entry NP_079390.3 (GeneID 80184).
isotype :
IgG
purity :
Immunogen affinity purified
species :
Human,Mouse
theoretical molecular weight :
290 kDa
gene symbol :
CEP290
accessionNumbers :
NP_079390.3
applications :
Immunoprecipitation,Western Blot,Immunocytochemistry/ Immunofluorescence
USD :
459 USD
alt names :
BBS14Bardet-Biedl syndrome 14 protein, Cancer/testis antigen 87, centrosomal protein 290kDa, Cep290, CT87JBTS6, FLJ13615, JBTS5CTCL tumor antigen se2-2, KIAA0373FLJ21979, LCA10monoclonal 3H11 antigen, MKS4, Nephrocystin-6, NPHP6centrosomal protein of 290 kDa, POC3, POC3 centriolar protein homolog, prostate cancer antigen T21, rd16,3H11AG, SLSN6nephrocytsin-6,3H11Ag, Tumor antigen se2-2
storage :
Store at 4C. Do not freeze.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.