GSK-3 beta [p Tyr279, p Tyr216] Antibody | Novus Biologicals NB100-81946 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

GSK-3 beta [p Tyr279, p Tyr216] Antibody

catalog :

NB100-81946

quantity :

0.05 ml (also 0.025 ml)

price :

409 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

more info or order :

Novus Biologicals product webpage

citations: 10

Reference
Toshima T, Yagi M, Do Y, Hirai H, Kunisaki Y, Kang D, et al. Mitochondrial translation failure represses cholesterol gene expression via Pyk2-Gsk3β-Srebp2 axis. Life Sci Alliance. 2024;7: pubmed publisher
Xu M, Lantz M, Nichols R, Li Q. Anti-Neuroinflammatory Effects of a Semi-Synthetic Isoorientin-Based Glycogen Synthase Kinase-3β Inhibitor in Lipopolysaccharide-Activated Microglial Cells. ACS Chem Neurosci. 2022;13:43-52 pubmed publisher
Hsing C, Tsai C, Chen C, Lin Y, Tseng P, Satria R, et al. Pharmacologically Inhibiting Glycogen Synthase Kinase-3β Ameliorates Renal Inflammation and Nephrotoxicity in an Animal Model of Cisplatin-Induced Acute Kidney Injury. Biomedicines. 2021;9: pubmed publisher
Takaichi Y, Chambers J, Ano Y, Takashima A, Nakayama H, Uchida K. Deposition of Phosphorylated α-Synuclein and Activation of GSK-3β and PP2A in the PS19 Mouse Model of Tauopathy. J Neuropathol Exp Neurol. 2021;80:731-740 pubmed publisher
Takaichi Y, Chambers J, Takahashi K, Soeda Y, Koike R, Katsumata E, et al. Amyloid β and tau pathology in brains of aged pinniped species (sea lion, seal, and walrus). Acta Neuropathol Commun. 2021;9:10 pubmed publisher
Wu L, Lin W, Liao Q, Wang H, Lin C, Tang L, et al. Calcium Channel Blocker Nifedipine Suppresses Colorectal Cancer Progression and Immune Escape by Preventing NFAT2 Nuclear Translocation. Cell Rep. 2020;33:108327 pubmed publisher
Liu Z, Selby C, Yang Y, Lindsey Boltz L, Cao X, Eynullazada K, et al. Circadian regulation of c-MYC in mice. Proc Natl Acad Sci U S A. 2020;117:21609-21617 pubmed publisher
Takaichi Y, Chambers J, Inoue H, Ano Y, Takashima A, Nakayama H, et al. Phosphorylation and oligomerization of α-synuclein associated with GSK-3β activation in the rTg4510 mouse model of tauopathy. Acta Neuropathol Commun. 2020;8:86 pubmed publisher
Wu X, Kosaraju J, Tam K. Anti-neuroinflammatory effects of SLOH in Aβ-induced BV-2 microglial cells and 3xTg-AD mice involve the inhibition of GSK-3β. Neurosci Lett. 2018;687:207-215 pubmed publisher
Wu X, Kosaraju J, Zhou W, Tam K. SLOH, a carbazole-based fluorophore, mitigates neuropathology and behavioral impairment in the triple-transgenic mouse model of Alzheimer's disease. Neuropharmacology. 2018;131:351-363 pubmed publisher

product information

brand :

Novus

master code :

NB100-81946

SKU :

NB100-81946

product name :

GSK-3 beta [p Tyr279, p Tyr216] Antibody

unit size :

0.05 ml (also 0.025 ml)

seo description :

The GSK-3 beta [p Tyr279, p Tyr216] Antibody - BSA Free from Novus is a rabbit polyclonal antibody to GSK-3 beta. This antibody reacts with human,mammal,mouse,rat. The GSK-3 beta [p Tyr279, p Tyr216] Antibody - BSA Free has been validated for the following applications: IF/IHC,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry,Immunocytochemistry/ Immunofluorescence.

target :

GSK-3 beta

category :

Primary Antibodies

buffer :

0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol

clonality :

Polyclonal

concentration :

1.0 mg/ml

conjugate :

Unconjugated

dilution :

Western Blot 1:500-1:1000, Immunohistochemistry 1:100-1:200, Immunocytochemistry/ Immunofluorescence 1:100-1:200, Immunohistochemistry-Paraffin 1:10-1:500

host :

Rabbit

immunogen :

The antiserum was produced against synthesized phosphopeptide derived from human GSK-3 beta around the phosphorylation site of tyrosine 279/216 (V-S-YP-I-C).

isotype :

IgG

purity :

Immunogen affinity purified

species :

Human,Mammal,Mouse,Rat

specificity :

Detects endogenous levels of GSK-3 beta only when phosphorylated at tyrosine 216/279

theoretical molecular weight :

46 kDa

gene symbol :

GSK3B

accessionNumbers :

P49841

applications :

Immunohistochemistry,Immunocytochemistry/ Immunofluorescence,IF/IHC,Western Blot,Immunohistochemistry-Paraffin

USD :

409 USD

alt names :

EC 2.7.11, EC 2.7.11.26, glycogen synthase kinase 3 beta, glycogen synthase kinase-3 beta, GSK-3 beta, GSK3beta isoform

storage :

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

more info or order :

Novus Biologicals product webpage