CRM1 Antibody | Novus Biologicals NB100-79802 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

CRM1 Antibody

catalog :

NB100-79802

quantity :

0.1 ml

price :

469 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section

more info or order :

Novus Biologicals product webpage

citations: 10

Reference
Kim W, Buckley A, Lee D, Hiroto A, Nenninger C, Olson A, et al. Androgen deprivation induces double-null prostate cancer via aberrant nuclear export and ribosomal biogenesis through HGF and Wnt activation. Nat Commun. 2024;15:1231 pubmed publisher
Wang X, Fan D, Han Q, Liu Y, Miao H, Wang X, et al. Mutant NPM1 Hijacks Transcriptional Hubs to Maintain Pathogenic Gene Programs in Acute Myeloid Leukemia. Cancer Discov. 2023;13:724-745 pubmed publisher
Gorostieta Salas E, Moreno Blas D, Gerónimo Olvera C, Cisneros B, Court F, Castro Obregon S. Enhanced Activity of Exportin-1/CRM1 in Neurons Contributes to Autophagy Dysfunction and Senescent Features in Old Mouse Brain. Oxid Med Cell Longev. 2021;2021:6682336 pubmed publisher
Meiners A, Bäcker S, Hadrović I, Heid C, Beuck C, Ruiz Blanco Y, et al. Specific inhibition of the Survivin-CRM1 interaction by peptide-modified molecular tweezers. Nat Commun. 2021;12:1505 pubmed publisher
Balukoff N, Ho J, Theodoridis P, Wang M, Bokros M, Llanio L, et al. A translational program that suppresses metabolism to shield the genome. Nat Commun. 2020;11:5755 pubmed publisher
Agote Aran A, Schmucker S, Jerabkova K, Jmel Boyer I, Berto A, Pacini L, et al. Spatial control of nucleoporin condensation by fragile X-related proteins. EMBO J. 2020;39:e104467 pubmed publisher
García Aguirre I, Alamillo Iniesta A, Rodríguez Pérez R, Vélez Aguilera G, Amaro Encarnación E, Jiménez Gutiérrez E, et al. Enhanced nuclear protein export in premature aging and rescue of the progeria phenotype by modulation of CRM1 activity. Aging Cell. 2019;18:e13002 pubmed publisher
Shakhparonov M, Antipova N, Shender V, Shnaider P, Arapidi G, Pestov N, et al. Expression and Intracellular Localization of Paraoxonase 2 in Different Types of Malignancies. Acta Naturae. 2018;10:92-99 pubmed
Vélez Aguilera G, de Dios Gómez López J, Jiménez Gutiérrez G, Vásquez Limeta A, Laredo Cisneros M, Gomez P, et al. Control of nuclear ?-dystroglycan content is crucial for the maintenance of nuclear envelope integrity and function. Biochim Biophys Acta Mol Cell Res. 2018;1865:406-420 pubmed publisher
Vercruysse T, De Bie J, Neggers J, Jacquemyn M, Vanstreels E, Schmid Burgk J, et al. The Second-Generation Exportin-1 Inhibitor KPT-8602 Demonstrates Potent Activity against Acute Lymphoblastic Leukemia. Clin Cancer Res. 2017;23:2528-2541 pubmed publisher

product information

brand :

Novus

master code :

NB100-79802

SKU :

NB100-79802

product name :

CRM1 Antibody

unit size :

0.1 ml

seo description :

The CRM1 Antibody - BSA Free from Novus is a rabbit polyclonal antibody to CRM1. This antibody reacts with human,mouse,rat. The CRM1 Antibody - BSA Free has been validated for the following applications: Simple Western,Immunoprecipitation,Western Blot,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry,Immunohistochemistry-Paraffin.

target :

CRM1

category :

Primary Antibodies

buffer :

Tris-Citrate/Phosphate (pH 7.0 - 8.0)

clonality :

Polyclonal

concentration :

1.0 mg/ml

conjugate :

Unconjugated

dilution :

Western Blot 1:2000-1:10000, Simple Western 1:500, Immunohistochemistry 1:1000-1:5000, Immunocytochemistry/ Immunofluorescence 1:1000 to 1:10000, Immunoprecipitation 2-10 ug/mg lysate, Immunohistochemistry-Paraffin 1:1000-1:5000

host :

Rabbit

immunogen :

The immunogen recognized by this antibody maps to a region between residue 1025 and the C-terminus (residue 1071) of human Chromosome Region Maintenance 1 (Exportin 1) (NP_003391.1).

isotype :

IgG

purity :

Immunogen affinity purified

species :

Human,Mouse,Rat

theoretical molecular weight :

123 kDa

gene symbol :

XPO1

Antibody validation :

Independent Antibodies

accessionNumbers :

O14980

applications :

Immunohistochemistry,Immunohistochemistry-Paraffin,Immunoprecipitation,Western Blot,Simple Western,Immunocytochemistry/ Immunofluorescence

USD :

469 USD

alt names :

Chromosome region maintenance 1 protein homolog, DKFZp686B1823, emb, exp1, exportin 1 (CRM1 homolog, yeast), exportin 1 (CRM1, yeast, homolog), exportin-1, Exportin-1 (required for chromosome region maintenance), yeast, homolog

storage :

Store at 4C. Do not freeze.

more info or order :

Novus Biologicals product webpage