Notch-1 Antibody (mN1A) - BSA Free | Novus Biologicals NB100-78486 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

Notch-1 Antibody (mN1A) - BSA Free

catalog :

NB100-78486

quantity :

0.1 ml (also 0.025 ml)

price :

459 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

mN1A

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Novus Biologicals product webpage

citations: 10

Reference
Alghamdi T, Krentz N, Smith N, Spigelman A, Rajesh V, Jha A, et al. Zmiz1 is required for mature β-cell function and mass expansion upon high fat feeding. Mol Metab. 2022;66:101621 pubmed publisher
Gong M, Yan F, Yu L, Li F. A dopamine-methacrylated hyaluronic acid hydrogel as an effective carrier for stem cells in skin regeneration therapy. Cell Death Dis. 2022;13:738 pubmed publisher
Bai J, Khajavi M, Sui L, Fu H, Tarakkad Krishnaji S, Birsner A, et al. Angiogenic responses in a 3D micro-engineered environment of primary endothelial cells and pericytes. Angiogenesis. 2020;: pubmed publisher
Kang H, Yang K, Xiao L, Guo L, Guo C, Yan Y, et al. Osteoblast Hypoxia-Inducible Factor-1? Pathway Activation Restrains Osteoclastogenesis via the Interleukin-33-MicroRNA-34a-Notch1 Pathway. Front Immunol. 2017;8:1312 pubmed publisher
Singh N, Kotla S, Kumar R, Rao G. Cyclic AMP Response Element Binding Protein Mediates Pathological Retinal Neovascularization via Modulating DLL4-NOTCH1 Signaling. EBioMedicine. 2015;2:1767-84 pubmed publisher
Qiu H, Tang X, Ma J, Shaverdashvili K, Zhang K, Bedogni B. Notch1 Autoactivation via Transcriptional Regulation of Furin, Which Sustains Notch1 Signaling by Processing Notch1-Activating Proteases ADAM10 and Membrane Type 1 Matrix Metalloproteinase. Mol Cell Biol. 2015;35:3622-32 pubmed publisher
Jundt F, Acikgoz O, Kwon S, Schwarzer R, Anagnostopoulos I, Wiesner B, et al. Aberrant expression of Notch1 interferes with the B-lymphoid phenotype of neoplastic B cells in classical Hodgkin lymphoma. Leukemia. 2008;22:1587-94 pubmed publisher
Sun H, Li L, Vercherat C, Gulbagci N, Acharjee S, Li J, et al. Stra13 regulates satellite cell activation by antagonizing Notch signaling. J Cell Biol. 2007;177:647-57 pubmed
De Strooper B, Annaert W, Cupers P, Saftig P, Craessaerts K, Mumm J, et al. A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain. Nature. 1999;398:518-22 pubmed
Ray W, Yao M, Nowotny P, Mumm J, Zhang W, Wu J, et al. Evidence for a physical interaction between presenilin and Notch. Proc Natl Acad Sci U S A. 1999;96:3263-8 pubmed

product information

brand :

Novus

master code :

NB100-78486

SKU :

NB100-78486

product name :

Notch-1 Antibody (mN1A) - BSA Free

unit size :

0.1 ml (also 0.025 ml)

seo description :

The Notch-1 Antibody (mN1A) - BSA Free from Novus is a mouse monoclonal antibody to Notch-1. This antibody reacts with human,mouse,rat (negative). The Notch-1 Antibody (mN1A) - BSA Free has been validated for the following applications: IF/IHC,Immunoprecipitation,Western Blot,Immunohistochemistry-Frozen,Immunocytochemistry/ Immunofluorescence,Flow Cytometry,Immunohistochemistry,Immunohistochemistry-Paraffin,CyTOF-ready,Knockout Validated.

target :

Notch-1

category :

Primary Antibodies

buffer :

PBS

clonality :

Monoclonal

clone :

mN1A

concentration :

1.0 mg/ml

conjugate :

Unconjugated

dilution :

Western Blot 1 - 2 ug/mL, Flow Cytometry 1 ug per million cells, Immunohistochemistry 1:10 - 1:500, Immunocytochemistry/ Immunofluorescence 1:50 - 1:100, Immunoprecipitation 1:10 - 1:100, Immunohistochemistry-Paraffin 1:10 - 1:500, CyTOF-ready, Knockout Validated

host :

Mouse

immunogen :

Mouse Notch1 protein [Uniprot: Q01705]

isotype :

IgG1 Kappa

purity :

Protein G purified

species :

Human,Mouse,Rat (Negative)

specificity :

Does not cross-react with Notch 2, 3, or 4

theoretical molecular weight :

272.505 kDa

gene symbol :

NOTCH1

Antibody validation :

Knockout/Knockdown

accessionNumbers :

Q01705

applications :

Flow Cytometry,Immunohistochemistry,Immunohistochemistry-Paraffin,CyTOF-ready,Knockout Validated,IF/IHC,Immunoprecipitation,Western Blot,Immunohistochemistry-Frozen,Immunocytochemistry/ Immunofluorescence

USD :

459 USD

alt names :

EC 2.1.2.11, EC 3.4.21.68, hN1, Notch (Drosophila) homolog 1 (translocation-associated), notch 1Notch homolog 1, translocation-associated (Drosophila), Notch homolog 1, translocation-associated, TAN1neurogenic locus notch homolog protein 1, Translocation-associated notch protein TAN-1

storage :

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

more info or order :

Novus Biologicals product webpage