PSGL-1/CD162 Antibody (HECA-452) | Novus Biologicals NB100-78039 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

PSGL-1/CD162 Antibody (HECA-452)

catalog :

NB100-78039

quantity :

0.1 ml (also 0.025 ml)

price :

409 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

HECA-452

reactivity :

human, mouse

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, neutralization, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Novus Biologicals product webpage

citations: 7

Reference
Xu Q, Shi M, Ding L, Xia Y, Luo L, Lu X, et al. High expression of P-selectin induces neutrophil extracellular traps via the PSGL-1/Syk/Ca2+/PAD4 pathway to exacerbate acute pancreatitis. Front Immunol. 2023;14:1265344 pubmed publisher
Li G, Jiang X, Zang J, Zhu B, Jia C, Niu K, et al. B-cell receptor associated protein 31 deficiency decreases the expression of adhesion molecule CD11b/CD18 and PSGL-1 in neutrophils to ameliorate acute lung injury. Int J Biochem Cell Biol. 2022;152:106299 pubmed publisher
Shi H, Jiang C, Yao H, Zhang Y, Zhang Q, Hou X, et al. CD44 fucosylation on bone marrow-derived mesenchymal stem cells enhances homing and promotes enteric nervous system remodeling in diabetic mice. Cell Biosci. 2021;11:118 pubmed publisher
Yeini E, Ofek P, Pozzi S, Albeck N, Ben Shushan D, Tiram G, et al. P-selectin axis plays a key role in microglia immunophenotype and glioblastoma progression. Nat Commun. 2021;12:1912 pubmed publisher
Kim C, Cheong K, Park C, Lee A. Therapeutic effects of combination using glucosamine plus tacrolimus (FK-506) on the development of atopic dermatitis-like skin lesions in NC/Nga mice. Scand J Immunol. 2012;75:471-8 pubmed publisher
Yamanaka K, Dimitroff C, Fuhlbrigge R, Kakeda M, Kurokawa I, Mizutani H, et al. Vitamins A and D are potent inhibitors of cutaneous lymphocyte-associated antigen expression. J Allergy Clin Immunol. 2008;121:148-157.e3 pubmed
Walcheck B, Leppanen A, Cummings R, Knibbs R, Stoolman L, Alexander S, et al. The monoclonal antibody CHO-131 binds to a core 2 O-glycan terminated with sialyl-Lewis x, which is a functional glycan ligand for P-selectin. Blood. 2002;99:4063-9 pubmed

product information

brand :

Novus

master code :

NB100-78039

SKU :

NB100-78039

product name :

PSGL-1/CD162 Antibody (HECA-452)

unit size :

0.1 ml (also 0.025 ml)

seo description :

The PSGL-1/CD162 Antibody (HECA-452) - BSA Free from Novus is a rat monoclonal antibody to PSGL-1/CD162. This antibody reacts with human,mouse. The PSGL-1/CD162 Antibody (HECA-452) - BSA Free has been validated for the following applications: IF/IHC,ELISA,Flow Cytometry,Western Blot,Block/Neutralize,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Flow (Cell Surface),CyTOF-ready,Immunocytochemistry/ Immunofluorescence.

target :

PSGL-1/CD162

category :

Primary Antibodies

buffer :

PBS

clonality :

Monoclonal

clone :

HECA-452

concentration :

1.0 mg/ml

conjugate :

Unconjugated

dilution :

Western Blot 2 ug/ml, Flow Cytometry = 2 ug/10^6 cells in 100 ul, ELISA, Immunohistochemistry 1:10-1:500, Immunocytochemistry/ Immunofluorescence reported in scientific literature (PMID 1693467), Immunohistochemistry-Paraffin 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500, Flow (Cell Surface), CyTOF-ready

host :

Rat

immunogen :

Human tonsil stroma

isotype :

IgM Kappa

purity :

IgM purified

species :

Human,Mouse

specificity :

CLA antibody clone HECA-452 is known to recognize the cutaneous lymphocyte-associated antigen/ CLA which is a specialized glycosylated form of P-selectin glycoprotein ligand-1/PSGL-1

gene symbol :

SELPLG

applications :

Immunohistochemistry,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Flow (Cell Surface),CyTOF-ready,Immunocytochemistry/ Immunofluorescence,IF/IHC,Flow Cytometry,ELISA,Western Blot,Block/Neutralize

USD :

409 USD

alt names :

CD162, CD162 antigen, P-selectin glycoprotein ligand 1, PSGL1, PSGL-1cutaneous lymphocyte-associated associated antigen, selectin P ligandCLA

storage :

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

more info or order :

Novus Biologicals product webpage