HLA-DR Antibody (L243) - BSA Free | Novus Biologicals NB100-77855 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

HLA-DR Antibody (L243) - BSA Free

catalog :

NB100-77855

quantity :

0.1 ml (also 0.025 ml)

price :

399 USD

clonality :

monoclonal

host :

mouse

conjugate :

AF647

clone name :

L243

reactivity :

human, dogs

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, neutralization, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Novus Biologicals product webpage

citations: 27

Reference
Balmert S, Ghozloujeh Z, Carey C, Williams L, Zhang J, Shahi P, et al. A microarray patch SARS-CoV-2 vaccine induces sustained antibody responses and polyfunctional cellular immunity. iScience. 2022;25:105045 pubmed publisher
Bhargavan B, Woollard S, McMillan J, Kanmogne G. CCR5 antagonist reduces HIV-induced amyloidogenesis, tau pathology, neurodegeneration, and blood-brain barrier alterations in HIV-infected hu-PBL-NSG mice. Mol Neurodegener. 2021;16:78 pubmed publisher
Mo Y, Cheung A, Liu Y, Liu L, Chen Z. Imaging and analysis on the interaction between human antigen-pulsed Vδ2 T cells and antigen-specific CD4 T cells. STAR Protoc. 2021;2:100453 pubmed publisher
Liu L, Fang C, Fu W, Jiang B, Li G, Qin L, et al. Endothelial Cell-Derived Interleukin-18 Released During Ischemia Reperfusion Injury Selectively Expands T Peripheral Helper Cells to Promote Alloantibody Production. Circulation. 2020;141:464-478 pubmed publisher
Shibutani M, Maeda K, Nagahara H, Fukuoka T, Matsutani S, Kashiwagi S, et al. A comparison of the local immune status between the primary and metastatic tumor in colorectal cancer: a retrospective study. BMC Cancer. 2018;18:371 pubmed publisher
Waghmare V, Rong J, Rogers C, Bowers J, Chee P, Gannaway J, et al. Comparative transmission genetics of introgressed chromatin in Gossypium (cotton) polyploids. Am J Bot. 2016;103:719-29 pubmed publisher
Kuo F, Histed S, Xu B, Bhadrasetty V, Szajek L, Williams M, et al. Immuno-PET imaging of tumor endothelial marker 8 (TEM8). Mol Pharm. 2014;11:3996-4006 pubmed publisher
Oza V, Ashwell S, Almeida L, Brassil P, Breed J, Deng C, et al. Discovery of checkpoint kinase inhibitor (S)-5-(3-fluorophenyl)-N-(piperidin-3-yl)-3-ureidothiophene-2-carboxamide (AZD7762) by structure-based design and optimization of thiophenecarboxamide ureas. J Med Chem. 2012;55:5130-42 pubmed publisher
Petersen S, Odintsova E, Haigh T, Rickinson A, Taylor G, Berditchevski F. The role of tetraspanin CD63 in antigen presentation via MHC class II. Eur J Immunol. 2011;41:2556-61 pubmed publisher
Ivanov A, Beers S, Walshe C, Honeychurch J, Alduaij W, Cox K, et al. Monoclonal antibodies directed to CD20 and HLA-DR can elicit homotypic adhesion followed by lysosome-mediated cell death in human lymphoma and leukemia cells. J Clin Invest. 2009;119:2143-59 pubmed publisher
Apps R, Murphy S, Fernando R, Gardner L, Ahad T, Moffett A. Human leucocyte antigen (HLA) expression of primary trophoblast cells and placental cell lines, determined using single antigen beads to characterize allotype specificities of anti-HLA antibodies. Immunology. 2009;127:26-39 pubmed publisher
Wahlstrom J, Dengjel J, Persson B, Duyar H, Rammensee H, Stevanovic S, et al. Identification of HLA-DR-bound peptides presented by human bronchoalveolar lavage cells in sarcoidosis. J Clin Invest. 2007;117:3576-82 pubmed
Setterblad N, Garban F, Weigl R, Assier E, Drillat P, Charron D, et al. Extracorporeal photophoresis increases sensitivity of monocytes from patients with graft-versus-host disease to HLA-DR-mediated cell death. Transfusion. 2008;48:169-77 pubmed
Dengjel J, Schoor O, Fischer R, Reich M, Kraus M, Müller M, et al. Autophagy promotes MHC class II presentation of peptides from intracellular source proteins. Proc Natl Acad Sci U S A. 2005;102:7922-7 pubmed
Ovsyannikova I, Johnson K, Naylor S, Poland G. Identification of HLA-DRB1-bound self-peptides following measles virus infection. J Immunol Methods. 2005;297:153-67 pubmed
Pashine A, Busch R, Belmares M, Munning J, Doebele R, Buckingham M, et al. Interaction of HLA-DR with an acidic face of HLA-DM disrupts sequence-dependent interactions with peptides. Immunity. 2003;19:183-92 pubmed
Gehring A, Rojas R, Canaday D, Lakey D, Harding C, Boom W. The Mycobacterium tuberculosis 19-kilodalton lipoprotein inhibits gamma interferon-regulated HLA-DR and Fc gamma R1 on human macrophages through Toll-like receptor 2. Infect Immun. 2003;71:4487-97 pubmed
Hegde N, Tomazin R, Wisner T, Dunn C, Boname J, Lewinsohn D, et al. Inhibition of HLA-DR assembly, transport, and loading by human cytomegalovirus glycoprotein US3: a novel mechanism for evading major histocompatibility complex class II antigen presentation. J Virol. 2002;76:10929-41 pubmed
Patil N, Pashine A, Belmares M, Liu W, Kaneshiro B, Rabinowitz J, et al. Rheumatoid arthritis (RA)-associated HLA-DR alleles form less stable complexes with class II-associated invariant chain peptide than non-RA-associated HLA-DR alleles. J Immunol. 2001;167:7157-68 pubmed
Kostelny S, Link B, Tso J, Vasquez M, Jorgensen B, Wang H, et al. Humanization and characterization of the anti-HLA-DR antibody 1D10. Int J Cancer. 2001;93:556-65 pubmed
Doebele R, Busch R, Scott H, Pashine A, Mellins E. Determination of the HLA-DM interaction site on HLA-DR molecules. Immunity. 2000;13:517-27 pubmed
Bainbridge D, Ellis S, Sargent I. HLA-G suppresses proliferation of CD4(+) T-lymphocytes. J Reprod Immunol. 2000;48:17-26 pubmed
van Ham M, van Lith M, Lillemeier B, Tjin E, Gruneberg U, Rahman D, et al. Modulation of the major histocompatibility complex class II-associated peptide repertoire by human histocompatibility leukocyte antigen (HLA)-DO. J Exp Med. 2000;191:1127-36 pubmed
Texier C, Pouvelle S, Busson M, Herve M, Charron D, Menez A, et al. HLA-DR restricted peptide candidates for bee venom immunotherapy. J Immunol. 2000;164:3177-84 pubmed
Bertho N, Drenou B, Laupeze B, Berre C, Amiot L, Grosset J, et al. HLA-DR-mediated apoptosis susceptibility discriminates differentiation stages of dendritic/monocytic APC. J Immunol. 2000;164:2379-85 pubmed
Appel H, Gauthier L, Pyrdol J, Wucherpfennig K. Kinetics of T-cell receptor binding by bivalent HLA-DR. Peptide complexes that activate antigen-specific human T-cells. J Biol Chem. 2000;275:312-21 pubmed
Hohn H, Pilch H, Günzel S, Neukirch C, Hilmes C, Kaufmann A, et al. CD4+ tumor-infiltrating lymphocytes in cervical cancer recognize HLA-DR-restricted peptides provided by human papillomavirus-E7. J Immunol. 1999;163:5715-22 pubmed

product information

brand :

Novus

master code :

NB100-77855

SKU :

NB100-77855

product name :

HLA-DR Antibody (L243) - BSA Free

unit size :

0.1 ml (also 0.025 ml)

seo description :

The HLA-DR Antibody (L243) - BSA Free from Novus is a mouse monoclonal antibody to HLA-DR. This antibody reacts with baboon,canine,human,primate. The HLA-DR Antibody (L243) - BSA Free has been validated for the following applications: ICC/F,IF/IHC,ELISA,Flow Cytometry,Immunoprecipitation,Western Blot,Immunohistochemistry-Frozen,In vitro assay,Electron Microscopy,Fluorophore-linked immunosorbent assay,Block/Neutralize,Functional Assay,Immunohistochemistry,Immunohistochemistry-Paraffin,Functional,Flow (Cell Surface),CyTOF-ready,Dual RNAscope ISH-IHC,Immunocytochemistry/ Immunofluorescence.

target :

HLA-DR

category :

Primary Antibodies

buffer :

PBS

clonality :

Monoclonal

clone :

L243

concentration :

1.0 mg/ml

conjugate :

Unconjugated

dilution :

Western Blot 1:100 - 1:2000, Flow Cytometry 0.5 ug/10^6 cells, ELISA reported in scientific literature (PMID 11070170), Immunohistochemistry 1:10 - 1:500, Immunocytochemistry/ Immunofluorescence reported in scientific literature (PMID 7835916), Immunoprecipitation 1:10 - 1:500, Immunohistochemistry-Paraffin 1:100, Immunohistochemistry-Frozen 1:10 - 1:500, Functional reported in scientific literature (PMID 17900279), In vitro assay reported in scientific literature (PMID 19620786), Electron Microscopy reported in scientific literature (PMID 21660937), Flow (Cell Surface), CyTOF-ready, Block/Neutralize reported in scientific literature (PMID 12874328), Dual RNAscope ISH-IHC

host :

Mouse

immunogen :

Human lymphoblastoid cell line (RPMI 8866).

isotype :

IgG2a Kappa

purity :

Protein A purified

species :

Baboon,Canine,Human,Primate

theoretical molecular weight :

28 kDa

gene symbol :

HLA-DRA

Antibody validation :

Orthogonal Validation

applications :

Immunohistochemistry,Immunohistochemistry-Paraffin,Functional,Flow (Cell Surface),CyTOF-ready,Dual RNAscope ISH-IHC,Immunocytochemistry/ Immunofluorescence,ICC/F,IF/IHC,Flow Cytometry,ELISA,Immunoprecipitation,Western Blot,Immunohistochemistry-Frozen,In vitro assay,Electron Microscopy,Fluorophore-linked immunosorbent assay,Block/Neutralize,Functional Assay

USD :

399 USD

alt names :

FLJ51114, histocompatibility antigen HLA-DR alpha, HLA class II histocompatibility antigen, DR alpha chain, HLA-DRA1, major histocompatibility complex, class II, DR alpha, MHC cell surface glycoprotein, MHC class II antigen DRA, MLRW

storage :

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

more info or order :

Novus Biologicals product webpage