CD14 Antibody (M5E2) - BSA Free | Novus Biologicals NB100-77758 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

CD14 Antibody (M5E2) - BSA Free

catalog :

NB100-77758

quantity :

0.1 mg (also 0.025 mg, 0.5 mg)

price :

269 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

M5E2

reactivity :

human, dogs, bovine

application :

western blot, immunohistochemistry, immunocytochemistry, neutralization, flow cytometry, immunohistochemistry - frozen section

more info or order :

Novus Biologicals product webpage

citations: 46

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - frozen section; human; 1:100; loading ...; fig 2a	Gherardini J, Uchida Y, Hardman J, Chéret J, Mace K, Bertolini M, et al. Tissue-resident macrophages can be generated de novo in adult human skin from resident progenitor cells during substance P-mediated neurogenic inflammation ex vivo. PLoS ONE. 2020;15:e0227817 pubmed publisher
	Spindler L, Feuerhake A, Ladel S, G xfc nday C, Flamm J, G xfc nday T xfc reli N, et al. Nano-in-Micro-Particles Consisting of PLGA Nanoparticles Embedded in Chitosan Microparticles via Spray-Drying Enhances Their Uptake in the Olfactory Mucosa. Front Pharmacol. 2021;12:732954 pubmed publisher
	Sekiguchi M, Seki M, Kawai T, Yoshida K, Yoshida M, Isobe T, et al. Integrated multiomics analysis of hepatoblastoma unravels its heterogeneity and provides novel druggable targets. NPJ Precis Oncol. 2020;4:20 pubmed publisher
	Chatterjee A, Kosmacek E, Shrishrimal S, McDonald J, Oberley Deegan R. MnTE-2-PyP, a manganese porphyrin, reduces cytotoxicity caused by irradiation in a diabetic environment through the induction of endogenous antioxidant defenses. Redox Biol. 2020;34:101542 pubmed publisher
	Shrishrimal S, Chatterjee A, Kosmacek E, Davis P, McDonald J, Oberley Deegan R. Manganese porphyrin, MnTE-2-PyP, treatment protects the prostate from radiation-induced fibrosis (RIF) by activating the NRF2 signaling pathway and enhancing SOD2 and sirtuin activity. Free Radic Biol Med. 2020;152:255-270 pubmed publisher
	Nitta S, Kusakari Y, Yamada Y, Kubo T, Neo S, Igarashi H, et al. Conversion of mesenchymal stem cells into a canine hepatocyte-like cells by Foxa1 and Hnf4a. Regen Ther. 2020;14:165-176 pubmed publisher
	Amin S, Anderson K, Boudreau C, Martinez Ledesma E, Kocakavuk E, Johnson K, et al. Comparative Molecular Life History of Spontaneous Canine and Human Gliomas. Cancer Cell. 2020;37:243-257.e7 pubmed publisher
	Serafini M, Catanzaro M, Fagiani F, Simoni E, Caporaso R, Dacrema M, et al. Modulation of Keap1/Nrf2/ARE Signaling Pathway by Curcuma- and Garlic-Derived Hybrids. Front Pharmacol. 2019;10:1597 pubmed publisher
	Kakiuchi Kiyota S, Obert L, Crowell D, Xia S, Roy M, Coskran T, et al. Expression of Hematopoietic Stem and Endothelial Cell Markers in Canine Hemangiosarcoma. Toxicol Pathol. 2020;48:481-493 pubmed publisher
	Petrillo S, D Amico J, La Rosa P, Bertini E, Piemonte F. Targeting NRF2 for the Treatment of Friedreich's Ataxia: A Comparison among Drugs. Int J Mol Sci. 2019;20: pubmed publisher
	La Rosa P, Russo M, D Amico J, Petrillo S, Aquilano K, Lettieri Barbato D, et al. Nrf2 Induction Re-establishes a Proper Neuronal Differentiation Program in Friedreich's Ataxia Neural Stem Cells. Front Cell Neurosci. 2019;13:356 pubmed publisher
	Yim S, Clish C, Gladyshev V. Selenium Deficiency Is Associated with Pro-longevity Mechanisms. Cell Rep. 2019;27:2785-2797.e3 pubmed publisher
	Peng J, Zhou F, Wang Y, Xu Y, Zhang H, Zou F, et al. Differential response to lead toxicity in rat primary microglia and astrocytes. Toxicol Appl Pharmacol. 2018;363:64-71 pubmed publisher
	Wang Y, Feng F, Liu M, Xue J, Huang H. Resveratrol ameliorates sepsis-induced acute kidney injury in a pediatric rat model via Nrf2 signaling pathway. Exp Ther Med. 2018;16:3233-3240 pubmed publisher
	Bricambert J, Alves Guerra M, Esteves P, Prip Buus C, Bertrand Michel J, Guillou H, et al. The histone demethylase Phf2 acts as a molecular checkpoint to prevent NAFLD progression during obesity. Nat Commun. 2018;9:2092 pubmed publisher
	Bertolo A, Pavlicek D, Gemperli A, Baur M, Pötzel T, Stoyanov J. Increased motility of mesenchymal stem cells is correlated with inhibition of stimulated peripheral blood mononuclear cells in vitro. J Stem Cells Regen Med. 2017;13:62-74 pubmed
	Chen C, Chen Y, Sung P, Sun C, Chen K, Chen Y, et al. Effective protection against acute respiratory distress syndrome/sepsis injury by combined adipose-derived mesenchymal stem cells and preactivated disaggregated platelets. Oncotarget. 2017;8:82415-82429 pubmed publisher
	Shrishrimal S, Kosmacek E, Chatterjee A, Tyson M, Oberley Deegan R. The SOD Mimic, MnTE-2-PyP, Protects from Chronic Fibrosis and Inflammation in Irradiated Normal Pelvic Tissues. Antioxidants (Basel). 2017;6: pubmed publisher
	Petrillo S, Piermarini E, Pastore A, Vasco G, Schirinzi T, Carrozzo R, et al. Nrf2-Inducers Counteract Neurodegeneration in Frataxin-Silenced Motor Neurons: Disclosing New Therapeutic Targets for Friedreich's Ataxia. Int J Mol Sci. 2017;18: pubmed publisher
	Waksman R, Lipinski M, Acampado E, Cheng Q, Adams L, Torii S, et al. Comparison of Acute Thrombogenicity for Metallic and Polymeric Bioabsorbable Scaffolds: Magmaris Versus Absorb in a Porcine Arteriovenous Shunt Model. Circ Cardiovasc Interv. 2017;10: pubmed publisher
	Simoni E, Serafini M, Caporaso R, Marchetti C, Racchi M, Minarini A, et al. Targeting the Nrf2/Amyloid-Beta Liaison in Alzheimer's Disease: A Rational Approach. ACS Chem Neurosci. 2017;8:1618-1627 pubmed publisher
	Kim J, Lim J, Kang B, Jung K, Choi H. Capillarisin augments anti-oxidative and anti-inflammatory responses by activating Nrf2/HO-1 signaling. Neurochem Int. 2017;105:11-20 pubmed publisher
	Bertolo A, Capossela S, Fränkl G, Baur M, Pötzel T, Stoyanov J. Oxidative status predicts quality in human mesenchymal stem cells. Stem Cell Res Ther. 2017;8:3 pubmed publisher
	Zhang T, Hu Q, Shi L, Qin L, Zhang Q, Mi M. Equol Attenuates Atherosclerosis in Apolipoprotein E-Deficient Mice by Inhibiting Endoplasmic Reticulum Stress via Activation of Nrf2 in Endothelial Cells. PLoS ONE. 2016;11:e0167020 pubmed publisher
	He Z, Riva M, Björk P, Swärd K, Morgelin M, Leanderson T, et al. CD14 Is a Co-Receptor for TLR4 in the S100A9-Induced Pro-Inflammatory Response in Monocytes. PLoS ONE. 2016;11:e0156377 pubmed publisher
	Qin T, Yin S, Yang J, Zhang Q, Liu Y, Huang F, et al. Sinomenine attenuates renal fibrosis through Nrf2-mediated inhibition of oxidative stress and TGF? signaling. Toxicol Appl Pharmacol. 2016;304:1-8 pubmed publisher
	Qin T, Du R, Huang F, Yin S, Yang J, Qin S, et al. Sinomenine activation of Nrf2 signaling prevents hyperactive inflammation and kidney injury in a mouse model of obstructive nephropathy. Free Radic Biol Med. 2016;92:90-99 pubmed publisher
	BouÅ¡ovÃ¡ I, BÃ¡rtÃkovÃ¡ H, MatouÅ¡kovÃ¡ P, LnÄ›niÄkovÃ¡ K, Zappe L, ValentovÃ¡ K, et al. Cranberry extract-enriched diets increase NAD(P)H:quinone oxidoreductase and catalase activities in obese but not in nonobese mice. Nutr Res. 2015;35:901-9 pubmed publisher
	Qin S, Du R, Yin S, Liu X, Xu G, Cao W. Nrf2 is essential for the anti-inflammatory effect of carbon monoxide in LPS-induced inflammation. Inflamm Res. 2015;64:537-48 pubmed publisher
	Bertolo A, Gemperli A, Gruber M, Gantenbein B, Baur M, PÃ¶tzel T, et al. In vitro cell motility as a potential mesenchymal stem cell marker for multipotency. Stem Cells Transl Med. 2015;4:84-90 pubmed publisher
	Bertolo A, Steffen F, Malonzo Marty C, Stoyanov J. Canine Mesenchymal Stem Cell Potential and the Importance of Dog Breed: Implication for Cell-Based Therapies. Cell Transplant. 2015;24:1969-80 pubmed publisher
	Suyama K, Watanabe M, Sakabe K, Otomo A, Okada Y, Terayama H, et al. GRP78 suppresses lipid peroxidation and promotes cellular antioxidant levels in glial cells following hydrogen peroxide exposure. PLoS ONE. 2014;9:e86951 pubmed publisher
	Zhang T, Liang X, Shi L, Wang L, Chen J, Kang C, et al. Estrogen receptor and PI3K/Akt signaling pathway involvement in S-(-)equol-induced activation of Nrf2/ARE in endothelial cells. PLoS ONE. 2013;8:e79075 pubmed publisher
	Wang B, Zhu X, Kim Y, Li J, Huang S, Saleem S, et al. Histone deacetylase inhibition activates transcription factor Nrf2 and protects against cerebral ischemic damage. Free Radic Biol Med. 2012;52:928-36 pubmed publisher
	Gao M, Singh A, Macri K, Reynolds C, Singhal V, Biswal S, et al. Antioxidant components of naturally-occurring oils exhibit marked anti-inflammatory activity in epithelial cells of the human upper respiratory system. Respir Res. 2011;12:92 pubmed publisher
	Solis L, Behrens C, Dong W, Suraokar M, Ozburn N, Moran C, et al. Nrf2 and Keap1 abnormalities in non-small cell lung carcinoma and association with clinicopathologic features. Clin Cancer Res. 2010;16:3743-53 pubmed publisher
	Li C, Kim M, Godoy L, Thiantanawat A, Trudel L, Wogan G. Nitric oxide activation of Keap1/Nrf2 signaling in human colon carcinoma cells. Proc Natl Acad Sci U S A. 2009;106:14547-51 pubmed publisher
	Salama S, Kamel M, Diaz Arrastia C, Xu X, Veenstra T, Salih S, et al. Effect of tumor necrosis factor-alpha on estrogen metabolism and endometrial cells: potential physiological and pathological relevance. J Clin Endocrinol Metab. 2009;94:285-93 pubmed publisher
	Cho H, Imani F, Miller DeGraff L, Walters D, Melendi G, Yamamoto M, et al. Antiviral activity of Nrf2 in a murine model of respiratory syncytial virus disease. Am J Respir Crit Care Med. 2009;179:138-50 pubmed publisher
	Lee J, Bhora F, Sun J, Cheng G, Arguiri E, Solomides C, et al. Dietary flaxseed enhances antioxidant defenses and is protective in a mouse model of lung ischemia-reperfusion injury. Am J Physiol Lung Cell Mol Physiol. 2008;294:L255-65 pubmed
	Dehn D, Siegel D, Zafar K, Reigan P, Swann E, Moody C, et al. 5-Methoxy-1,2-dimethyl-3-[(4-nitrophenoxy)methyl]indole-4,7-dione, a mechanism-based inhibitor of NAD(P)H:quinone oxidoreductase 1, exhibits activity against human pancreatic cancer in vitro and in vivo. Mol Cancer Ther. 2006;5:1702-9 pubmed
	Slitt A, Cherrington N, Dieter M, Aleksunes L, Scheffer G, Huang W, et al. trans-Stilbene oxide induces expression of genes involved in metabolism and transport in mouse liver via CAR and Nrf2 transcription factors. Mol Pharmacol. 2006;69:1554-63 pubmed
	Zhang J, Schulz W, Li Y, Wang R, Zotz R, Wen D, et al. Association of NAD(P)H: quinone oxidoreductase 1 (NQO1) C609T polymorphism with esophageal squamous cell carcinoma in a German Caucasian and a northern Chinese population. Carcinogenesis. 2003;24:905-9 pubmed
	Anwar A, Dehn D, Siegel D, Kepa J, Tang L, Pietenpol J, et al. Interaction of human NAD(P)H:quinone oxidoreductase 1 (NQO1) with the tumor suppressor protein p53 in cells and cell-free systems. J Biol Chem. 2003;278:10368-73 pubmed
	Siegel D, Anwar A, Winski S, Kepa J, Zolman K, Ross D. Rapid polyubiquitination and proteasomal degradation of a mutant form of NAD(P)H:quinone oxidoreductase 1. Mol Pharmacol. 2001;59:263-8 pubmed
	Siegel D, Ross D. Immunodetection of NAD(P)H:quinone oxidoreductase 1 (NQO1) in human tissues. Free Radic Biol Med. 2000;29:246-53 pubmed

product information

brand :

Novus

master code :

NB100-77758

SKU :

NB100-77758

product name :

CD14 Antibody (M5E2) - BSA Free

unit size :

0.1 mg (also 0.025 mg, 0.5 mg)

seo description :

The CD14 Antibody (M5E2) - BSA Free from Novus is a mouse monoclonal antibody to CD14. This antibody reacts with bovine,canine,human,porcine,primate. The CD14 Antibody (M5E2) - BSA Free has been validated for the following applications: IF/IHC,Flow Cytometry,Immunohistochemistry,Western Blot,Block/Neutralize,Immunohistochemistry-Frozen,Simple Western,CyTOF-ready,Dual RNAscope ISH-IHC,Immunocytochemistry/ Immunofluorescence.

target :

CD14

category :

Primary Antibodies

buffer :

PBS

clonality :

Monoclonal

clone :

M5E2

concentration :

1.0 mg/ml

conjugate :

Unconjugated

dilution :

Simple Western 50 ug/ml, Flow Cytometry 2.0 ug/10^6 cells in 100 ul, Immunohistochemistry 1:10 - 1:500, Immunocytochemistry/ Immunofluorescence 1:10 - 1:500, Immunohistochemistry-Frozen 1:10 - 1:500, CyTOF-ready, Block/Neutralize reported in scientific literature (PMID 27228163), Dual RNAscope ISH-IHC

host :

Mouse

immunogen :

Human peripheral blood cells.

isotype :

IgG2a Kappa

purity :

Protein G purified

species :

Bovine,Canine,Human,Porcine,Primate

gene symbol :

CD14

applications :

Immunohistochemistry-Frozen,Simple Western,CyTOF-ready,Dual RNAscope ISH-IHC,Immunocytochemistry/ Immunofluorescence,IF/IHC,Flow Cytometry,Immunohistochemistry,Western Blot,Block/Neutralize

extended description :

Clone M5E2 was used by HLDA to establish CD designation.

USD :

269 USD

product details :

Clone M5E2 was used by HLDA to establish CD designation.

alt names :

CD14 antigen, CD14 molecule, monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein

storage :

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

more info or order :

Novus Biologicals product webpage