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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
Panendothelial Cell Antigen Antibody (MECA-32) - BSA Free
catalog :
NB100-77668
quantity :
0.5 mg (also 0.1 mg)
price :
399 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
MECA-32
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 34
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; 1:50; loading ...; fig e8d
Ramachandran P, Dobie R, Wilson Kanamori J, Dora E, Henderson B, Luu N, et al. Resolving the fibrotic niche of human liver cirrhosis at single-cell level. Nature. 2019;575:512-518 pubmed publisher
  • immunohistochemistry; mouse; 1:50; loading ...; fig 3g
Yanai H, Atsumi N, Tanaka T, Nakamura N, Komai Y, Omachi T, et al. Intestinal stem cells contribute to the maturation of the neonatal small intestine and colon independently of digestive activity. Sci Rep. 2017;7:9891 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; fig 6
Sharmin S, Taguchi A, Kaku Y, Yoshimura Y, Ohmori T, Sakuma T, et al. Human Induced Pluripotent Stem Cell-Derived Podocytes Mature into Vascularized Glomeruli upon Experimental Transplantation. J Am Soc Nephrol. 2016;27:1778-91 pubmed publisher
Stokes M, Calvo V, Fujisawa S, Dudgeon C, Huang S, Ballal N, et al. PERK Inhibition by HC-5404 Sensitizes Renal Cell Carcinoma Tumor Models to Antiangiogenic Tyrosine Kinase Inhibitors. Clin Cancer Res. 2023;29:4870-4882 pubmed publisher
Kushwaha R, Li Y, Makarava N, Pandit N, Molesworth K, Birukov K, et al. Reactive astrocytes associated with prion disease impair the blood brain barrier. Neurobiol Dis. 2023;185:106264 pubmed publisher
Wang X, Zhou Y, Sun Q, Zhang Q, Zhou H, Zhang J, et al. Thymosin β4 Exerts a Cytoprotective Function and Attenuates Liver Injury in Murine Hepatic Sinusoidal Obstruction Syndrome after Hematopoietic Stem Cell Transplantation. Transplant Cell Ther. 2023;29:492.e1-492.e10 pubmed publisher
Prasad R, Adu Agyeiwaah Y, Floyd J, Asare Bediako B, Li Calzi S, Chakraborty D, et al. Sustained ACE2 Expression by Probiotic Improves Integrity of Intestinal Lymphatics and Retinopathy in Type 1 Diabetic Model. J Clin Med. 2023;12: pubmed publisher
Xu L, Nirwane A, Xu T, Kang M, Devasani K, Yao Y. Fibroblasts repair blood-brain barrier damage and hemorrhagic brain injury via TIMP2. Cell Rep. 2022;41:111709 pubmed publisher
Zhu S, Liang J, Zhu F, Zhang X, Xu M, Zhao K, et al. The effects of myeloablative or non-myeloablative total body irradiations on intestinal tract in mice. Biosci Rep. 2021;41: pubmed publisher
Wang C, Yuan W, Hu A, Lin J, Xia Z, Yang C, et al. Dexmedetomidine alleviated sepsis‑induced myocardial ferroptosis and septic heart injury. Mol Med Rep. 2020;22:175-184 pubmed publisher
Yang Y, Karsli Uzunbas G, Poillet Perez L, Sawant A, Hu Z, Zhao Y, et al. Autophagy promotes mammalian survival by suppressing oxidative stress and p53. Genes Dev. 2020;34:688-700 pubmed publisher
Marinho T, Borges C, Aguila M, Mandarim de Lacerda C. Intermittent fasting benefits on alpha- and beta-cell arrangement in diet-induced obese mice pancreatic islet. J Diabetes Complications. 2020;34:107497 pubmed publisher
Vanslambrouck J, Wilson S, Tan K, Soo J, Scurr M, Spijker H, et al. A Toolbox to Characterize Human Induced Pluripotent Stem Cell-Derived Kidney Cell Types and Organoids. J Am Soc Nephrol. 2019;30:1811-1823 pubmed publisher
Tran T, Guha R, Portugal S, Skinner J, Ongoiba A, Bhardwaj J, et al. A Molecular Signature in Blood Reveals a Role for p53 in Regulating Malaria-Induced Inflammation. Immunity. 2019;51:750-765.e10 pubmed publisher
Noval Rivas M, Wakita D, Franklin M, Carvalho T, Abolhesn A, Gomez A, et al. Intestinal Permeability and IgA Provoke Immune Vasculitis Linked to Cardiovascular Inflammation. Immunity. 2019;51:508-521.e6 pubmed publisher
Fujimoto T, Colbert L, Huang Y, Molkentine J, Deorukhkar A, Baseler L, et al. Selective EGLN Inhibition Enables Ablative Radiotherapy and Improves Survival in Unresectable Pancreatic Cancer. Cancer Res. 2019;79:2327-2338 pubmed publisher
Yang X, Zhao T, Feng L, Shi Y, Jiang J, Liang S, et al. PM2.5-induced ADRB2 hypermethylation contributed to cardiac dysfunction through cardiomyocytes apoptosis via PI3K/Akt pathway. Environ Int. 2019;127:601-614 pubmed publisher
Pich C, Meylan P, Mastelic Gavillet B, Nguyen T, Loyon R, Trang B, et al. Induction of Paracrine Signaling in Metastatic Melanoma Cells by PPARγ Agonist Rosiglitazone Activates Stromal Cells and Enhances Tumor Growth. Cancer Res. 2018;78:6447-6461 pubmed publisher
Wang X, Pan B, Honda G, Wang X, Hashimoto Y, Ohkawara H, et al. Cytoprotective and pro-angiogenic functions of thrombomodulin are preserved in the C loop of the fifth epidermal growth factor-like domain. Haematologica. 2018;103:1730-1740 pubmed publisher
Kutwin M, Sawosz E, Jaworski S, Hinzmann M, Wierzbicki M, Hotowy A, et al. Investigation of platinum nanoparticle properties against U87 glioblastoma multiforme. Arch Med Sci. 2017;13:1322-1334 pubmed publisher
Graham N, Minasyan A, Lomova A, Cass A, Balanis N, Friedman M, et al. Recurrent patterns of DNA copy number alterations in tumors reflect metabolic selection pressures. Mol Syst Biol. 2017;13:914 pubmed publisher
Tărlungeanu D, Deliu E, Dotter C, Kara M, Janiesch P, Scalise M, et al. Impaired Amino Acid Transport at the Blood Brain Barrier Is a Cause of Autism Spectrum Disorder. Cell. 2016;167:1481-1494.e18 pubmed publisher
Shi M, Ma L, Zhou L, Fu P. Renal Protective Effects of 17β-Estradiol on Mice with Acute Aristolochic Acid Nephropathy. Molecules. 2016;21: pubmed
Ge X, Pettan Brewer C, Morton J, Carter K, Fatemi S, Rabinovitch P, et al. Mitochondrial catalase suppresses naturally occurring lung cancer in old mice. Pathobiol Aging Age Relat Dis. 2015;5:28776 pubmed publisher
Biswas A, Mitchell D, Johnson D. E2F1 responds to ultraviolet radiation by directly stimulating DNA repair and suppressing carcinogenesis. Cancer Res. 2014;74:3369-77 pubmed publisher
Pippin J, Sparks M, Glenn S, Buitrago S, Coffman T, Duffield J, et al. Cells of renin lineage are progenitors of podocytes and parietal epithelial cells in experimental glomerular disease. Am J Pathol. 2013;183:542-57 pubmed publisher
Lange S, Bedford E, Reh S, Wittschieben J, Carbajal S, Kusewitt D, et al. Dual role for mammalian DNA polymerase ? in maintaining genome stability and proliferative responses. Proc Natl Acad Sci U S A. 2013;110:E687-96 pubmed publisher
Pan S, Wu L, Chen C, Shieh S, Chiu H. Angiogenin expression in burn blister fluid: implications for its role in burn wound neovascularization. Wound Repair Regen. 2012;20:731-9 pubmed publisher
Ma L, Young J, Prabhala H, Pan E, Mestdagh P, Muth D, et al. miR-9, a MYC/MYCN-activated microRNA, regulates E-cadherin and cancer metastasis. Nat Cell Biol. 2010;12:247-56 pubmed publisher
Jensen M, Factor V, Fantozzi A, Helin K, Huh C, Thorgeirsson S. Reduced hepatic tumor incidence in cyclin G1-deficient mice. Hepatology. 2003;37:862-70 pubmed
Ran S, Downes A, Thorpe P. Increased exposure of anionic phospholipids on the surface of tumor blood vessels. Cancer Res. 2002;62:6132-40 pubmed
Mandriota S, Jussila L, Jeltsch M, Compagni A, Baetens D, Prevo R, et al. Vascular endothelial growth factor-C-mediated lymphangiogenesis promotes tumour metastasis. EMBO J. 2001;20:672-82 pubmed
Asher G, Lotem J, Cohen B, Sachs L, Shaul Y. Regulation of p53 stability and p53-dependent apoptosis by NADH quinone oxidoreductase 1. Proc Natl Acad Sci U S A. 2001;98:1188-93 pubmed
Tanneau G, Hibrand Saint Oyant L, Chevaleyre C, Salmon H. Differential recruitment of T- and IgA B-lymphocytes in the developing mammary gland in relation to homing receptors and vascular addressins. J Histochem Cytochem. 1999;47:1581-92 pubmed
product information
brand :
Novus Biologicals, a Bio-Techne Brand
catalog number base :
NB100-77668
SKU :
NB100-77668
product name :
Panendothelial Cell Antigen Antibody (MECA-32) - BSA Free
Description :
The Panendothelial Cell Antigen Antibody (MECA-32) - BSA Free from Novus is a rat monoclonal antibody to Panendothelial Cell Antigen. This antibody reacts with human, mouse. The Panendothelial Cell Antigen Antibody (MECA-32) - BSA Free has been validated for the following applications: Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/ Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, CyTOF-ready.
target :
Panendothelial Cell Antigen
category :
Primary Antibodies
unit size :
0.5 mg (also 0.1 mg)
buffer :
PBS
clonality :
Monoclonal
clone :
MECA-32
concentration :
1.0 mg/ml
conjugate :
Unconjugated
host :
Rat
immunogen :
Mouse lymph node stromal cells.
isotype :
IgG2a Kappa
purity :
Protein G purified
species :
Human, Mouse
specificity :
Pan endothelial cells except for CNS & muscle capillaries
gene symbol :
Plvap
accessionNumbers :
Q91VC4
applications :
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/ Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, CyTOF-ready
USD :
399 USD
alt names :
FELS, Fenestrated endothelial-linked structure protein, gp68, MECA32, MECA-32, Panendothelial Cell Antigen, plasmalemma vesicle associated protein, Plasmalemma Vesicle Protein 1, PV-1 protein
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.