product summary
request information :
company name :
Novus Biologicals
product type :
antibody
product name :
Rat Monoclonal Integrin beta 2/CD18 Antibody
catalog :
NB100-77379C
quantity :
0.1 mg
price :
429.00 USD
clonality :
monoclonal
host :
rat
reactivity :
human, mouse
application :
western blot, immunoprecipitation, immunohistochemistry, flow cytometry
more info or order :
Novus Biologicals product webpage
product information
Catalog Number :
NB100-77379C
Product Name :
Rat Monoclonal Integrin beta 2/CD18 Antibody
List Price :
429.00 USD
Product Type :
Primary Antibodies
Package Size :
0.1 mg
AltNames :
959 beta subunit precursor)10, CD18 antigen, CD18beta 2, cell surface adhesion glycoprotein (LFA-1, CR3, integrin beta-2, integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1;macrophage antigen 1 (mac-1) beta subunit), integrin, beta 2 (complement component 3 receptor 3 and 4 subunit), LCAMB, leukocyte cell adhesion molecule CD18, LAD, leukocyte-associated antigens CD18/11A, CD18/11B, CD18/11C, MFI7, MF17, P150
Background :
CD18 is a 95 kD protein, also known as integrin beta2 subunit. It is expressed on all leukocytes. CD18, in association with integrin alpha chain CD11a, CD11b, and CD11c forms LFA-1, Mac-1, and alphaX beta2, respectively, and plays an important role in leukocytes adhesion. The CD18 integrin complexes bind ICAM-1 (CD54), ICAM-2 (CD102), ICAM-3 (CD50), iC3b, and fibrinogen. The M18/2 antibody is able to block tumor cell metastasis and enhance cell adhesion.
Buffer :
50mM sodium borate
Clonality :
Monoclonal
Clone :
M18/2
Concentration :
1.0 mg/ml
Conjugate :
DyLight 650
Application Summary :
Western Blot, Flow Cytometry, Immunohistochemistry, Immunoprecipitation
Host :
Rat
Immunogen :
Mouse CTL glycoprotein
Isotype :
IgG2a Kappa
Preservative :
No Preservative
Purity :
Immunogen affinity purified
CrossReactivity :
Mouse
Specificity :
CD18 (M18/2)
Storage :
Store at 4C in the dark.
Uses :
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is: 0.5 microgram per one million cells in 100 microliter volume. Immunohistochemistry. It is recommended that the reagent be titrated for optimal performance for each application.
Research Area :
Apoptosis, Cytokine Research, Immunology
more info or order :
Novus Biologicals product webpage
company information
Novus Biologicals
8100 Southpark Way, A-8
Littleton, CO 80120
novus@novusbio.com
www.novusbio.com
3037301950
headquarters: usa
The mission of Novus Biologicals, LLC is to accelerate scientific discovery by developing and marketing unique products in the forefront of science. Novus Biologicals was organized to provide the biological research community with a mechanism for commercializing unique biological materials. We also focus on continually monitoring scientific trends and supply materials to serve these trends. By making these products widely available to institutional and commercial researchers, Novus Biologicals plays an important role in furthering biological research. All of Novus Biologicals products are supplied with detailed technical information and ongoing support. By serving niche and emerging markets, Novus Biologicals has become specialists in markets and has formed and will continue to form ongoing partnerships with our customers.