Astrin Antibody | Novus Biologicals NB100-74638 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

Astrin Antibody

catalog :

NB100-74638

quantity :

100 ul

price :

459 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

OC2-2A6

reactivity :

human

application :

western blot, immunocytochemistry, neutralization, immunoprecipitation

more info or order :

Novus Biologicals product webpage

citations: 9

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; human; 1:1000; loading ...; fig 2d	Conti D, Gul P, Islam A, Martín Durán J, Pickersgill R, Draviam V. Kinetochores attached to microtubule-ends are stabilised by Astrin bound PP1 to ensure proper chromosome segregation. elife. 2019;8: pubmed publisher
	Schatton D, Di Pietro G, Szczepanowska K, Veronese M, Marx M, Braun xf6 hler K, et al. CLUH controls astrin-1 expression to couple mitochondrial metabolism to cell cycle progression. elife. 2022;11: pubmed publisher
	Song X, Conti D, Shrestha R, Braun D, Draviam V. Counteraction between Astrin-PP1 and Cyclin-B-CDK1 pathways protects chromosome-microtubule attachments independent of biorientation. Nat Commun. 2021;12:7010 pubmed publisher
	Scott S, Li X, Jammula S, Devonshire G, Lindon C, Fitzgerald R, et al. Evidence that polyploidy in esophageal adenocarcinoma originates from mitotic slippage caused by defective chromosome attachments. Cell Death Differ. 2021;28:2179-2193 pubmed publisher
	Shrestha R, Rossi A, Wangsa D, Hogan A, Zaldana K, Suva E, et al. CENP-A overexpression promotes aneuploidy with karyotypic heterogeneity. J Cell Biol. 2021;220: pubmed publisher
	Gama Braga L, Cisneros A, Mathieu M, Clerc M, Garcia P, Lottin B, et al. BUBR1 Pseudokinase Domain Promotes Kinetochore PP2A-B56 Recruitment, Spindle Checkpoint Silencing, and Chromosome Alignment. Cell Rep. 2020;33:108397 pubmed publisher
	Shrestha R, Conti D, Tamura N, Braun D, Ramalingam R, Cieśliński K, et al. Aurora-B kinase pathway controls the lateral to end-on conversion of kinetochore-microtubule attachments in human cells. Nat Commun. 2017;8:150 pubmed publisher
	Dorrell C, Erker L, Schug J, Kopp J, Canaday P, Fox A, et al. Prospective isolation of a bipotential clonogenic liver progenitor cell in adult mice. Genes Dev. 2011;25:1193-203 pubmed publisher
	Dorrell C, Erker L, Lanxon Cookson K, Abraham S, Victoroff T, Ro S, et al. Surface markers for the murine oval cell response. Hepatology. 2008;48:1282-91 pubmed publisher

product information

brand :

Novus Biologicals, a Bio-Techne brand

catalog number base :

NB100-74638

SKU :

NB100-74638

product name :

Astrin Antibody

description :

The Astrin Antibody from Novus Biologicals is a rabbit polyclonal antibody to Astrin. This antibody reacts with human. The Astrin Antibody has been validated for the following applications: Immunoprecipitation,Western Blot (Negative),Block/Neutralize,Immunocytochemistry/ Immunofluorescence.

target :

Astrin

unit size :

100 ul

category :

Primary Antibodies

buffer :

Tris-Citrate/Phosphate (pH 7.0 - 8.0)

clonality :

Polyclonal

concentration :

1.0 mg/ml

conjugate :

Unconjugated

host :

Rabbit

immunogen :

The immunogen recognized by this antibody maps to a region between residue 1 and 50 of human astrin (mitotic spindle associated protein p126) using the numbering given in entry NP_006452.3 (GeneID 10615).

isotype :

IgG

purity :

Immunogen affinity purified

species :

Human

storage :

Store at 4C. Do not freeze.

gene symbol :

SPAG5

Antibody validation :

Independent Antibodies

accessionNumbers :

Q96R06

applications :

Immunoprecipitation,Western Blot (Negative),Block/Neutralize,Immunocytochemistry/ Immunofluorescence

USD :

449

USD 2025 :

459 USD

alt names :

Astrin, Deepest, hMAP126, MAP126mitotic spindle coiled-coil related protein, mitotic spindle associated protein p126, Mitotic spindle-associated protein p126, sperm associated antigen 5, sperm-associated antigen 5

more info or order :

Novus Biologicals product webpage