product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
SREBP2 Antibody
catalog :
NB100-74543
quantity :
100 ug (also 0.025 mg)
price :
379 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
10F1/6
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry
more info or order :
citations: 15
Reference
Quiroz Figueroa K, Vitali C, Conlon D, Millar J, Tobias J, Bauer R, et al. TRIB1 regulates LDL metabolism through CEBPα-mediated effects on the LDL receptor in hepatocytes. J Clin Invest. 2021;131: pubmed publisher
Chu T, Tu X, Yang K, Wu J, Repa J, Yan N. Tonic prime-boost of STING signalling mediates Niemann-Pick disease type C. Nature. 2021;596:570-575 pubmed publisher
Sharma B, Gupta V, Dahiya D, Kumar H, Vaiphei K, Agnihotri N. Clinical relevance of cholesterol homeostasis genes in colorectal cancer. Biochim Biophys Acta Mol Cell Biol Lipids. 2019;1864:1314-1327 pubmed publisher
Nguyen T, Ishida C, Shang E, Shu C, Bianchetti E, Karpel Massler G, et al. Activation of LXR Receptors and Inhibition of TRAP1 Causes Synthetic Lethality in Solid Tumors. Cancers (Basel). 2019;11: pubmed publisher
Lee E, Kim M, Kim Y, Park J, Park W. Proteasome inhibition protects against diet-induced gallstone formation through modulation of cholesterol and bile acid homeostasis. Int J Mol Med. 2018;41:1715-1723 pubmed publisher
Chun J, Buechelmaier E, Powell S. Rad51 paralog complexes BCDX2 and CX3 act at different stages in the BRCA1-BRCA2-dependent homologous recombination pathway. Mol Cell Biol. 2013;33:387-95 pubmed publisher
Sage J, Gildemeister O, Knight K. Discovery of a novel function for human Rad51: maintenance of the mitochondrial genome. J Biol Chem. 2010;285:18984-90 pubmed publisher
Gildemeister O, Sage J, Knight K. Cellular redistribution of Rad51 in response to DNA damage: novel role for Rad51C. J Biol Chem. 2009;284:31945-52 pubmed publisher
Shammas M, Shmookler Reis R, Koley H, Batchu R, Li C, Munshi N. Dysfunctional homologous recombination mediates genomic instability and progression in myeloma. Blood. 2009;113:2290-7 pubmed publisher
Li B, Jog S, Reddy S, Comai L. WRN controls formation of extrachromosomal telomeric circles and is required for TRF2DeltaB-mediated telomere shortening. Mol Cell Biol. 2008;28:1892-904 pubmed publisher
Chan N, Koritzinsky M, Zhao H, Bindra R, Glazer P, Powell S, et al. Chronic hypoxia decreases synthesis of homologous recombination proteins to offset chemoresistance and radioresistance. Cancer Res. 2008;68:605-14 pubmed publisher
Compton S, Choi J, Cesare A, Ozgur S, Griffith J. Xrcc3 and Nbs1 are required for the production of extrachromosomal telomeric circles in human alternative lengthening of telomere cells. Cancer Res. 2007;67:1513-9 pubmed
Bennett B, Knight K. Cellular localization of human Rad51C and regulation of ubiquitin-mediated proteolysis of Rad51. J Cell Biochem. 2005;96:1095-109 pubmed
Fan R, Kumaravel T, Jalali F, Marrano P, Squire J, Bristow R. Defective DNA strand break repair after DNA damage in prostate cancer cells: implications for genetic instability and prostate cancer progression. Cancer Res. 2004;64:8526-33 pubmed
Forget A, Bennett B, Knight K. Xrcc3 is recruited to DNA double strand breaks early and independent of Rad51. J Cell Biochem. 2004;93:429-36 pubmed
product information
brand :
Novus
master code :
NB100-74543
SKU :
NB100-74543
product name :
SREBP2 Antibody
description :
The SREBP2 Antibody from NB100-74543 is a nb100-74543 antibody to . The SREBP2 Antibody has been validated for the following applications: Q3T1I5.
target :
SREBP2
category :
Primary Antibodies
unit sizes :
100 ug (also 0.025 mg)
buffer :
PBS with 1 mg/ml BSA
clonality :
Polyclonal
concentration :
1 mg/ml
conjugate :
Unconjugated
host :
Rabbit
immunogen :
Synthetic peptide corresponding to residues A(843) I S W L Q G D D A A V R S H(857) of rat SREBP 2.
isotype :
IgG
purity :
Immunogen affinity purified
species :
Human, Mouse, Rat
specificity :
SREBP2
gene symbol :
SREBF2
accessionNumbers :
Q3T1I5
applications :
Western Blot, Immunocytochemistry/Immunofluorescence
USD :
379 USD
alt names :
BHLHD2, bHLHd2sterol regulatory element-binding protein 2, Class D basic helix-loop-helix protein 2, SREBP2, SREBP2SREBP-2, sterol regulatory element binding transcription factor 2, Sterol regulatory element-binding transcription factor 2
storage :
Store at -20C. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.