Presenilin-1 Antibody (APS 18) | Novus Biologicals NB100-74510 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

Presenilin-1 Antibody (APS 18)

catalog :

NB100-74510

quantity :

200 ug (also 50 ug)

price :

409 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

APS 18

reactivity :

human, mouse, rat

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section

more info or order :

Novus Biologicals product webpage

citations: 11

Reference
Zhang H, Jiang R, Zhou J, Wang J, Xu Y, Zhang H, et al. CTL Attenuation Regulated by PS1 in Cancer-Associated Fibroblast. Front Immunol. 2020;11:999 pubmed publisher
Luo H, Zhu G, Xu J, Lai Q, Yan B, Guo Y, et al. HOTTIP lncRNA Promotes Hematopoietic Stem Cell Self-Renewal Leading to AML-like Disease in Mice. Cancer Cell. 2019;36:645-659.e8 pubmed publisher
Lv L, Li Q, Chen S, Zhang X, Tao X, Tang X, et al. miR-133b suppresses colorectal cancer cell stemness and chemoresistance by targeting methyltransferase DOT1L. Exp Cell Res. 2019;385:111597 pubmed publisher
Liu B, Yang L, Zhu X, Li H, Zhu P, Wu J, et al. Yeats4 drives ILC lineage commitment via activation of Lmo4 transcription. J Exp Med. 2019;216:2653-2668 pubmed publisher
Szablewski V, Bret C, Kassambara A, Devin J, Cartron G, Costes Martineau V, et al. An epigenetic regulator-related score (EpiScore) predicts survival in patients with diffuse large B cell lymphoma and identifies patients who may benefit from epigenetic therapy. Oncotarget. 2018;9:19079-19099 pubmed publisher
Loeser H, Waldschmidt D, Kuetting F, Heydt C, Zander T, Plum P, et al. Copy-number variation and protein expression of DOT1L in pancreatic adenocarcinoma as a potential drug target. Mol Clin Oncol. 2017;6:639-642 pubmed publisher
Lakhdar R, Drost E, MacNee W, Bastos R, Rabinovich R. 2D-DIGE proteomic analysis of vastus lateralis from COPD patients with low and normal fat free mass index and healthy controls. Respir Res. 2017;18:81 pubmed publisher
Gilan O, Lam E, Becher I, Lugo D, Cannizzaro E, Joberty G, et al. Functional interdependence of BRD4 and DOT1L in MLL leukemia. Nat Struct Mol Biol. 2016;23:673-81 pubmed publisher
McCombs J, Gibson E, Palmer A. Using a genetically targeted sensor to investigate the role of presenilin-1 in ER Ca2+ levels and dynamics. Mol Biosyst. 2010;6:1640-9 pubmed publisher
Diehlmann A, Ida N, Weggen S, Grunberg J, Haass C, Masters C, et al. Analysis of presenilin 1 and presenilin 2 expression and processing by newly developed monoclonal antibodies. J Neurosci Res. 1999;56:405-19 pubmed
Stahl B, Diehlmann A, Sudhof T. Direct interaction of Alzheimer's disease-related presenilin 1 with armadillo protein p0071. J Biol Chem. 1999;274:9141-8 pubmed

product information

brand :

Novus Biologicals, a Bio-Techne brand

catalog number base :

NB100-74510

SKU :

NB100-74510

product name :

Presenilin-1 Antibody (APS 18)

description :

The Presenilin-1 Antibody (APS 18) from Novus Biologicals is a mouse monoclonal antibody to Presenilin-1. This antibody reacts with human,mouse,primate,rat. The Presenilin-1 Antibody (APS 18) has been validated for the following applications: Immunohistochemistry,Immunohistochemistry-Paraffin,IF/IHC,ELISA,Immunoprecipitation,Western Blot,Immunocytochemistry/ Immunofluorescence.

target :

Presenilin-1

unit size :

200 ug (also 50 ug)

category :

Primary Antibodies

buffer :

PBS with 1 mg/ml BSA

clonality :

Monoclonal

clone :

APS 18

concentration :

1 mg/ml

conjugate :

Unconjugated

host :

Mouse

immunogen :

Synthetic peptide corresponding to residues C S(313) K Y N A E S T E R E S Q D T V A E N D D G(334) of humen PS1.

isotype :

IgG1

purity :

Protein G purified

species :

Human,Mouse,Primate,Rat

specificity :

Presenilin 1 (APS 18)

storage :

Store at -20C. Avoid freeze-thaw cycles.

gene symbol :

PSEN1

applications :

Immunohistochemistry,Immunohistochemistry-Paraffin,IF/IHC,ELISA,Immunoprecipitation,Western Blot,Immunocytochemistry/ Immunofluorescence

USD :

399

USD 2025 :

409 USD

alt names :

AD3EC 3.4.23.-, Alzheimer disease 3, EC 3.4.23, FAD, presenilin 1, Protein S182, PS-1, PS1presenilin-1, PSNL1, S182

more info or order :

Novus Biologicals product webpage