Histone H2AX [p Ser139] Antibody (3F2) | Novus Biologicals NB100-74435 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

Histone H2AX [p Ser139] Antibody (3F2)

catalog :

NB100-74435

quantity :

100 ug (also 0.025 mg)

price :

429 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3F2

reactivity :

human, mouse, bovine

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Novus Biologicals product webpage

citations: 20

Published Application/Species/Sample/Dilution	Reference
western blot; human; 1:1000; loading ...; fig 1a	Jia Y, Kang X, Tan L, Ren Y, Qu L, Tang J, et al. Nicotinamide Mononucleotide Attenuates Renal Interstitial Fibrosis After AKI by Suppressing Tubular DNA Damage and Senescence. Front Physiol. 2021;12:649547 pubmed publisher
immunohistochemistry - frozen section; mouse; loading ...; fig 2b	Pelz L, Purfürst B, Rathjen F. The cell adhesion molecule BT-IgSF is essential for a functional blood-testis barrier and male fertility in mice. J Biol Chem. 2017;292:21490-21503 pubmed publisher
	Kim K, Admasu T, Stolzing A, Sharma A. Enhanced co-culture and enrichment of human natural killer cells for the selective clearance of senescent cells. Aging (Albany NY). 2022;14:2131-2147 pubmed publisher
	P xe1 ramo M, Santamar xed a E, Idoate M, Rodr xed guez Fraile M, Benito A, Collantes M, et al. A new animal model of atrophy-hypertrophy complex and liver damage following Yttrium-90 lobar selective internal radiation therapy in rabbits. Sci Rep. 2022;12:1777 pubmed publisher
	Sugaya K. Characterization of cells expressing MRI reporters for the analysis of epigenetics. Anal Biochem. 2021;633:114395 pubmed publisher
	Wang H, Muthu Karuppan M, Devadoss D, Nair M, Chand H, LAKSHMANA M. TFEB protein expression is reduced in aged brains and its overexpression mitigates senescence-associated biomarkers and memory deficits in mice. Neurobiol Aging. 2021;106:26-36 pubmed publisher
	Bui T, Butin Israeli V, Wiesolek H, Zhou M, Rehring J, Wiesmuller L, et al. Neutrophils Alter DNA Repair Landscape to Impact Survival and Shape Distinct Therapeutic Phenotypes of Colorectal Cancer. Gastroenterology. 2021;161:225-238.e15 pubmed publisher
	Kobayashi Y, Tata A, Konkimalla A, Katsura H, Lee R, Ou J, et al. Persistence of a regeneration-associated, transitional alveolar epithelial cell state in pulmonary fibrosis. Nat Cell Biol. 2020;22:934-946 pubmed publisher
	Song J, Liu L, Lv L, Hu S, Tariq A, Wang W, et al. Fluid shear stress induces Runx-2 expression via upregulation of PIEZO1 in MC3T3-E1 cells. Cell Biol Int. 2020;44:1491-1502 pubmed publisher
	Smith J, Hart C, Ramos P, Akinsanya J, Lanza I, Joyner M, et al. Metabo- and mechanoreceptor expression in human heart failure: Relationships with the locomotor muscle afferent influence on exercise responses. Exp Physiol. 2020;105:809-818 pubmed publisher
	Morozumi W, Inagaki S, Iwata Y, Nakamura S, Hara H, Shimazawa M. Piezo channel plays a part in retinal ganglion cell damage. Exp Eye Res. 2020;191:107900 pubmed publisher
	Du G, Li L, Zhang X, Liu J, Hao J, Zhu J, et al. Roles of TRPV4 and piezo channels in stretch-evoked Ca2+ response in chondrocytes. Exp Biol Med (Maywood). 2020;245:180-189 pubmed publisher
	Miyazaki A, Sugimoto A, Yoshizaki K, Kawarabayashi K, Iwata K, Kurogoushi R, et al. Coordination of WNT signaling and ciliogenesis during odontogenesis by piezo type mechanosensitive ion channel component 1. Sci Rep. 2019;9:14762 pubmed publisher
	Elsaid M, Shahi A, Wang A, Baiu D, Li C, Werner L, et al. Enhanced Radiosensitivity in Solid Tumors using a Tumor-selective Alkyl Phospholipid Ether Analog. Mol Cancer Ther. 2018;17:2320-2328 pubmed publisher
	Etem E, Ceylan G, Ozaydin S, Ceylan C, Ozercan I, Kuloglu T. The increased expression of Piezo1 and Piezo2 ion channels in human and mouse bladder carcinoma. Adv Clin Exp Med. 2018;27:1025-1031 pubmed publisher
	Hayashi M, Yoshida K, Kitada K, Kizu A, Tachibana D, Fukui M, et al. Low-dose irradiation of mouse embryos increases Smad-p21 pathway activity and preserves pluripotency. J Assist Reprod Genet. 2018;35:1061-1069 pubmed publisher
	Szczepny A, Carey K, Mckenzie L, Jayasekara W, Rossello F, González Rajal A, et al. The tumor suppressor Hic1 maintains chromosomal stability independent of Tp53. Oncogene. 2018;37:1939-1948 pubmed publisher
	Jiang L, Zhao Y, Chen W. The Function of the Novel Mechanical Activated Ion Channel Piezo1 in the Human Osteosarcoma Cells. Med Sci Monit. 2017;23:5070-5082 pubmed
	Hatanaka M, Anderson Baucum E, Lakhter A, Kono T, Maier B, Tersey S, et al. Chronic high fat feeding restricts islet mRNA translation initiation independently of ER stress via DNA damage and p53 activation. Sci Rep. 2017;7:3758 pubmed publisher
	Lee K, Guevarra M, Nguyen A, Chua M, Wang Y, Jacobs C. The primary cilium functions as a mechanical and calcium signaling nexus. Cilia. 2015;4:7 pubmed publisher

product information

brand :

Novus

master code :

NB100-74435

SKU :

NB100-74435

product name :

Histone H2AX [p Ser139] Antibody (3F2)

description :

The Histone H2AX [p Ser139] Antibody (3F2) from Novus Biologicals is a mouse monoclonal antibody to Histone H2AX. This antibody reacts with human, mouse, bovine. The Histone H2AX [p Ser139] Antibody (3F2) has been validated for the following applications: Western Blot, Simple Western, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.

target :

Histone H2AX

category :

Primary Antibodies

sizes available :

100 ug (also 0.025 mg)

buffer :

PBS with 1 mg/ml BSA

clonality :

Monoclonal

clone :

3F2

concentration :

1 mg/ml

conjugate :

Unconjugated

host :

Mouse

immunogen :

This Histone H2AX [p Ser139] Antibody (3F2) was developed against a synthetic peptide sequence surrounding phosphorylated Ser139.

isotype :

IgG1 Kappa

purity :

Protein G purified

species :

Human, Mouse, Bovine

specificity :

In Western blot this antibody detects ~17 kDa protein representing phosphorylated H2AX in gamma irradiated HeLa cell lysate

theoretical molecular weight :

15 kDa

gene symbol :

H2AX

accessionNumbers :

P16104

applications :

Western Blot, Simple Western, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin

USD :

410

USD 2023 :

429 USD

alt names :

H2A.X, H2A/X, H2AFX

storage :

Store at -20C. Avoid freeze-thaw cycles.

more info or order :

Novus Biologicals product webpage