Granzyme B Antibody | Novus Biologicals NB100-684 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

Granzyme B Antibody

catalog :

NB100-684

quantity :

0.5 ml (also 0.1 ml)

price :

679 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

62N3G8

reactivity :

human

application :

immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Novus Biologicals product webpage

citations: 9

Reference
Chen X, Zhao J, Herjan T, Hong L, Liao Y, Liu C, et al. IL-17-induced HIF1α drives resistance to anti-PD-L1 via fibroblast-mediated immune exclusion. J Exp Med. 2022;219: pubmed publisher
Fujiwara H, Seike K, Brooks M, Mathew A, Kovalenko I, Pal A, et al. Mitochondrial complex II in intestinal epithelial cells regulates T cell-mediated immunopathology. Nat Immunol. 2021;22:1440-1451 pubmed publisher
Fang W, Zhou T, Shi H, Yao M, Zhang D, Qian H, et al. Progranulin induces immune escape in breast cancer via up-regulating PD-L1 expression on tumor-associated macrophages (TAMs) and promoting CD8+ T cell exclusion. J Exp Clin Cancer Res. 2021;40:4 pubmed publisher
Luchtel R, Bhagat T, Pradhan K, Jacobs W, Levine M, Verma A, et al. High-dose ascorbic acid synergizes with anti-PD1 in a lymphoma mouse model. Proc Natl Acad Sci U S A. 2020;117:1666-1677 pubmed publisher
Zhao Y, Lee C, Lin C, Gassen R, Xu X, Huang Z, et al. PD-L1:CD80 Cis-Heterodimer Triggers the Co-stimulatory Receptor CD28 While Repressing the Inhibitory PD-1 and CTLA-4 Pathways. Immunity. 2019;51:1059-1073.e9 pubmed publisher
Giles A, Hao S, Padget M, Song H, Zhang W, Lynes J, et al. Efficient ADCC killing of meningioma by avelumab and a high-affinity natural killer cell line, haNK. JCI Insight. 2019;4: pubmed publisher
Medler T, Murugan D, Horton W, Kumar S, Cotechini T, Forsyth A, et al. Complement C5a Fosters Squamous Carcinogenesis and Limits T Cell Response to Chemotherapy. Cancer Cell. 2018;34:561-578.e6 pubmed publisher
Herrera M, Söderberg M, Sabirsh A, Valastro B, Mölne J, Santamaria B, et al. Inhibition of T-cell activation by the CTLA4-Fc Abatacept is sufficient to ameliorate proteinuric kidney disease. Am J Physiol Renal Physiol. 2017;312:F748-F759 pubmed publisher
Gunderson A, Kaneda M, Tsujikawa T, Nguyen A, Affara N, Ruffell B, et al. Bruton Tyrosine Kinase-Dependent Immune Cell Cross-talk Drives Pancreas Cancer. Cancer Discov. 2016;6:270-85 pubmed publisher

product information

brand :

Novus Biologicals, a Bio-Techne brand

catalog number base :

NB100-684

SKU :

NB100-684

product name :

Granzyme B Antibody

description :

The Granzyme B Antibody from Novus Biologicals is a rabbit polyclonal antibody to Granzyme B. This antibody reacts with human,mouse. The Granzyme B Antibody has been validated for the following applications: Immunohistochemistry,Immunohistochemistry-Frozen,IF/IHC,Flow Cytometry,Immunohistochemistry-Paraffin,In vivo assay,Immunocytochemistry/ Immunofluorescence.

target :

Granzyme B

unit size :

0.5 ml (also 0.1 ml)

category :

Primary Antibodies

buffer :

PBS (pH 7.4), 0.2% BSA, Tween-20

clonality :

Polyclonal

conjugate :

Unconjugated

host :

Rabbit

immunogen :

Synthetic peptide: EIIGGHEAKPHSRPYMAYL, corresponding to amino acids 20-38 of Human Granzyme B (N-terminus).

isotype :

IgG

purity :

Affinity purified

species :

Human,Mouse

specificity :

This reacts with a 32 kDa protein

storage :

Store at 4C. Do not freeze.

gene symbol :

GZMB

applications :

Immunohistochemistry,Immunohistochemistry-Frozen,IF/IHC,Flow Cytometry,Immunohistochemistry-Paraffin,In vivo assay,Immunocytochemistry/ Immunofluorescence

USD :

669

USD 2025 :

679 USD

alt names :

C11, CCPI, CGL1, CGL-1, CSPB, CSP-B, CTLA1, CTSGL1, granzyme B, GranzymeB, GZMB, HLP, SECT

more info or order :

Novus Biologicals product webpage