product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
CD68/SR-D1 Antibody (KP1) - BSA Free
catalog :
NB100-683-0.1mg
quantity :
0.1 mg (also 0.025 mg, 0.5 ml)
price :
429 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
KP1
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 45
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; human; 1:200; loading ...; fig 2b
Jaworek C, Verel Yilmaz Y, Driesch S, Ostgathe S, Cook L, Wagner S, et al. Cohort Analysis of ADAM8 Expression in the PDAC Tumor Stroma. J Pers Med. 2021;11: pubmed publisher
Kater M, Huffels C, Oshima T, Renckens N, Middeldorp J, Boddeke E, et al. Prevention of microgliosis halts early memory loss in a mouse model of Alzheimer's disease. Brain Behav Immun. 2023;107:225-241 pubmed publisher
Zhai M, Gong S, Luan P, Shi Y, Kou W, Zeng Y, et al. Extracellular traps from activated vascular smooth muscle cells drive the progression of atherosclerosis. Nat Commun. 2022;13:7500 pubmed publisher
Real F, Zhu A, Huang B, Belmellat A, Sennepin A, Vogl T, et al. S100A8-mediated metabolic adaptation controls HIV-1 persistence in macrophages in vivo. Nat Commun. 2022;13:5956 pubmed publisher
Stock A, Parsons S, Sharma V, James F, Starkey G, D Costa R, et al. Intimal macrophages develop from circulating monocytes during vasculitis. Clin Transl Immunology. 2022;11:e1412 pubmed publisher
Rivellese F, Surace A, Goldmann K, Sciacca E, xc7 ubuk C, Giorli G, et al. Rituximab versus tocilizumab in rheumatoid arthritis: synovial biopsy-based biomarker analysis of the phase 4 R4RA randomized trial. Nat Med. 2022;28:1256-1268 pubmed publisher
Zhang S, Zhou Y, XIAN H, Shi Y, Liu Y, Li Z, et al. Nerve regeneration in rat peripheral nerve allografts: An assessment of the role of endogenous neurotrophic factors in nerve cryopreservation and regeneration. Eur J Neurosci. 2022;55:1895-1916 pubmed publisher
Gredic M, Wu C, Hadžić S, Pak O, Savai R, Kojonazarov B, et al. Myeloid cell-specific deletion of inducible nitric oxide synthase protects against smoke-induced pulmonary hypertension in mice. Eur Respir J. 2021;: pubmed publisher
Atta G, Schroedl F, Kaser Eichberger A, Spitzer G, Traweger A, Heindl L, et al. Scleraxis expressing scleral cells respond to inflammatory stimulation. Histochem Cell Biol. 2021;156:123-132 pubmed publisher
Jaén R, Fernandez Velasco M, Terrón V, Sánchez García S, Zaragoza C, Canales Bueno N, et al. BML-111 treatment prevents cardiac apoptosis and oxidative stress in a mouse model of autoimmune myocarditis. FASEB J. 2020;: pubmed publisher
Chen W, Lin C, Kuo S, Liu S, Lu Y, Chen Y, et al. Resistin Enhances VCAM-1 Expression and Monocyte Adhesion in Human Osteoarthritis Synovial Fibroblasts by Inhibiting MiR-381 Expression through the PKC, p38, and JNK Signaling Pathways. Cells. 2020;9: pubmed publisher
Wang M, Li H, Wang Y, Hao Y, Huang Y, Wang X, et al. Anti-Rheumatic Properties of Gentiopicroside Are Associated With Suppression of ROS-NF-κB-NLRP3 Axis in Fibroblast-Like Synoviocytes and NF-κB Pathway in Adjuvant-Induced Arthritis. Front Pharmacol. 2020;11:515 pubmed publisher
Schoenenberger A, Tempfer H, Lehner C, Egloff J, Mauracher M, Bird A, et al. Macromechanics and polycaprolactone fiber organization drive macrophage polarization and regulate inflammatory activation of tendon in vitro and in vivo. Biomaterials. 2020;249:120034 pubmed publisher
Liu Y, Li M, Wei C, Tang L, Sheng Y, Liu Y, et al. TSP1-CD47-SIRPα signaling facilitates the development of endometriosis by mediating the survival of ectopic endometrium. Am J Reprod Immunol. 2020;83:e13236 pubmed publisher
McCloskey C, Cook D, Kelly B, Azzi F, Allen C, Forsyth A, et al. Metformin Abrogates Age-Associated Ovarian Fibrosis. Clin Cancer Res. 2020;26:632-642 pubmed publisher
Liu X, Chen J, Zhang B, Liu G, Zhao H, Hu Q. KDM3A inhibition modulates macrophage polarization to aggravate post-MI injuries and accelerates adverse ventricular remodeling via an IRF4 signaling pathway. Cell Signal. 2019;64:109415 pubmed publisher
Wu Y, Qin Y, Liu Y, Zhu L, Zhao X, Liu Y, et al. Cardiac troponin I autoantibody induces myocardial dysfunction by PTEN signaling activation. EBioMedicine. 2019;47:329-340 pubmed publisher
Liu W, Kämpfe Nordström C, Danckwardt Lillieström N, Rask Andersen H. Human Inner Ear Immune Activity: A Super-Resolution Immunohistochemistry Study. Front Neurol. 2019;10:728 pubmed publisher
Ding J, Yin T, Yan N, Cheng Y, Yang J. FasL on decidual macrophages mediates trophoblast apoptosis: A potential cause of recurrent miscarriage. Int J Mol Med. 2019;43:2376-2386 pubmed publisher
Kämpfe Nordström C, Danckwardt Lillieström N, Laurell G, Liu W, Rask Andersen H. The Human Endolymphatic Sac and Inner Ear Immunity: Macrophage Interaction and Molecular Expression. Front Immunol. 2018;9:3181 pubmed publisher
Triulzi T, Forte L, Regondi V, Di Modica M, Ghirelli C, Carcangiu M, et al. HER2 signaling regulates the tumor immune microenvironment and trastuzumab efficacy. Oncoimmunology. 2019;8:e1512942 pubmed publisher
Triulzi T, Regondi V, De Cecco L, Cappelletti M, Di Modica M, Paolini B, et al. Early immune modulation by single-agent trastuzumab as a marker of trastuzumab benefit. Br J Cancer. 2018;119:1487-1494 pubmed publisher
van Rooijen J, Qiu S, Timmer Bosscha H, van der Vegt B, Boers J, Schröder C, et al. Androgen receptor expression inversely correlates with immune cell infiltration in human epidermal growth factor receptor 2-positive breast cancer. Eur J Cancer. 2018;103:52-60 pubmed publisher
Li D, Wang C, Li Z, Wang H, He J, Zhu J, et al. Nano-sized Al2O3 particle-induced autophagy reduces osteolysis in aseptic loosening of total hip arthroplasty by negative feedback regulation of RANKL expression in fibroblasts. Cell Death Dis. 2018;9:840 pubmed publisher
Xiang W, Shi R, Kang X, Zhang X, Chen P, Zhang L, et al. Monoacylglycerol lipase regulates cannabinoid receptor 2-dependent macrophage activation and cancer progression. Nat Commun. 2018;9:2574 pubmed publisher
Ao J, Zhu X, Chai Z, Cai H, Zhang Y, Zhang K, et al. Colony-Stimulating Factor 1 Receptor Blockade Inhibits Tumor Growth by Altering the Polarization of Tumor-Associated Macrophages in Hepatocellular Carcinoma. Mol Cancer Ther. 2017;16:1544-1554 pubmed publisher
Liu X, Guo X, Li J, Wu M, Zhan X. Interferon-? Aggravated L-Arginine-Induced Acute Pancreatitis in Sprague-Dawley Rats and Its Possible Mechanism: Trypsinogen Activation and Autophagy Up-regulation. Pancreas. 2017;46:619-625 pubmed publisher
Feng X, Weng D, Zhou F, Owen Y, Qin H, Zhao J, et al. Activation of PPAR? by a Natural Flavonoid Modulator, Apigenin Ameliorates Obesity-Related Inflammation Via Regulation of Macrophage Polarization. EBioMedicine. 2016;9:61-76 pubmed publisher
Miao H, Ou J, Peng Y, Zhang X, Chen Y, Hao L, et al. Macrophage ABHD5 promotes colorectal cancer growth by suppressing spermidine production by SRM. Nat Commun. 2016;7:11716 pubmed publisher
Koh M, Gagea M, Sargis T, Lemos R, Grandjean G, Charbono A, et al. A new HIF-1α/RANTES-driven pathway to hepatocellular carcinoma mediated by germline haploinsufficiency of SART1/HAF in mice. Hepatology. 2016;63:1576-91 pubmed publisher
Pandurangan A, Ismail S, Saadatdoust Z, Esa N. Allicin Alleviates Dextran Sodium Sulfate- (DSS-) Induced Ulcerative Colitis in BALB/c Mice. Oxid Med Cell Longev. 2015;2015:605208 pubmed publisher
Lin F, Hsiao F, Huang C, Shih C, Tsao N, Tsai C, et al. Porphyromonas gingivalis GroEL induces osteoclastogenesis of periodontal ligament cells and enhances alveolar bone resorption in rats. PLoS ONE. 2014;9:e102450 pubmed publisher
Joshi Barr S, Bett C, Chiang W, Trejo M, Goebel H, Sikorska B, et al. De novo prion aggregates trigger autophagy in skeletal muscle. J Virol. 2014;88:2071-82 pubmed publisher
Herwig M, Bergstrom C, Wells J, Höller T, Grossniklaus H. M2/M1 ratio of tumor associated macrophages and PPAR-gamma expression in uveal melanomas with class 1 and class 2 molecular profiles. Exp Eye Res. 2013;107:52-8 pubmed publisher
Spigoni V, Picconi A, Cito M, Ridolfi V, Bonomini S, Casali C, et al. Pioglitazone improves in vitro viability and function of endothelial progenitor cells from individuals with impaired glucose tolerance. PLoS ONE. 2012;7:e48283 pubmed publisher
Ayari H, Legedz L, Lantelme P, Feugier P, Randon J, Cerutti C, et al. Auto-amplification of cortisol actions in human carotid atheroma is linked to arterial remodeling and stroke. Fundam Clin Pharmacol. 2014;28:53-64 pubmed publisher
Chan C, Cheng L, Lin C, Huang Y, Lin H, Lee F. The protective role of natural phytoalexin resveratrol on inflammation, fibrosis and regeneration in cholestatic liver injury. Mol Nutr Food Res. 2011;55:1841-9 pubmed publisher
Della Puppa A, Persano L, Masi G, Rampazzo E, Sinigaglia A, Pistollato F, et al. MGMT expression and promoter methylation status may depend on the site of surgical sample collection within glioblastoma: a possible pitfall in stratification of patients?. J Neurooncol. 2012;106:33-41 pubmed publisher
Avouac J, Fürnrohr B, Tomcik M, Palumbo K, Zerr P, Horn A, et al. Inactivation of the transcription factor STAT-4 prevents inflammation-driven fibrosis in animal models of systemic sclerosis. Arthritis Rheum. 2011;63:800-9 pubmed publisher
Thenappan T, Goel A, Marsboom G, Fang Y, Toth P, Zhang H, et al. A central role for CD68(+) macrophages in hepatopulmonary syndrome. Reversal by macrophage depletion. Am J Respir Crit Care Med. 2011;183:1080-91 pubmed publisher
Canioni D, Salles G, Mounier N, Brousse N, Keuppens M, Morchhauser F, et al. High numbers of tumor-associated macrophages have an adverse prognostic value that can be circumvented by rituximab in patients with follicular lymphoma enrolled onto the GELA-GOELAMS FL-2000 trial. J Clin Oncol. 2008;26:440-6 pubmed
Lau S, Chu P, Weiss L. CD163: a specific marker of macrophages in paraffin-embedded tissue samples. Am J Clin Pathol. 2004;122:794-801 pubmed
King B, Crisi G, Tsai S, Haffty B, Phillips R, Rimm D. Immunocytochemical analysis of breast cells obtained by ductal lavage. Cancer. 2002;96:244-9 pubmed
Chang C, Eshoa C, Kampalath B, Shidham V, Perkins S. Immunophenotypic profile of myeloid cells in granulocytic sarcoma by immunohistochemistry. Correlation with blast differentiation in bone marrow. Am J Clin Pathol. 2000;114:807-11 pubmed
Mallat Z, Heymes C, Ohan J, Faggin E, Leseche G, Tedgui A. Expression of interleukin-10 in advanced human atherosclerotic plaques: relation to inducible nitric oxide synthase expression and cell death. Arterioscler Thromb Vasc Biol. 1999;19:611-6 pubmed
image
image 1 :
Novus Biologicals NB100-683-0.1mg image 1
Immunohistochemistry: CD68/SR-D1 Antibody (KP1) [NB100-683] - Representative images (40x) of infiltrated macrophages stained with anti-CD 68 in the gingiva. The black arrowheads indicate the infiltrated macrophages. The right graphs show the quantitative data of CD68-positive cells in HPF (magnification of 200x). Data are expressed as the mean +/- SEM of three slides. *p<0.05 compared with control cells. Image collected and cropped by CiteAb from the following publication (//doi.org/10.1371/journal.pone.0102450) licensed under a CC-BY licence.
product information
brand :
Novus
master code :
NB100-683
SKU :
NB100-683-0.1mg
product name :
CD68/SR-D1 Antibody (KP1) - BSA Free
description :
The CD68/SR-D1 Antibody (KP1) - BSA Free from Novus is a mouse monoclonal antibody to CD68/SR-D1. This antibody reacts with human, mouse, rat. The CD68/SR-D1 Antibody (KP1) - BSA Free has been validated for the following applications: Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Electron Microscopy, Dual RNAscope ISH-IHC.
target :
CD68/SR-D1
category :
Primary Antibodies
sizes available :
0.1 mg (also 0.025 mg, 0.5 ml)
buffer :
PBS
clonality :
Monoclonal
clone :
KP1
concentration :
1.0 mg/ml
conjugate :
Unconjugated
host :
Mouse
immunogen :
This CD68/SR-D1 Antibody (KP1) was developed against subcellular fraction of human alveolar macrophages.
isotype :
IgG1 Kappa
purity :
Protein G purified
species :
Human, Mouse, Rat
specificity :
This CD68/SR-D1 Antibody (KP1) is specific to macrophages in a wide variety of human tissues
gene symbol :
CD68
images :
https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/CD68-SR-D1-Antibody-(KP1)-Immunohistochemistry-NB100-683-img0009.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/CD68-SR-D1-Antibody-(KP1)-Immunohistochemistry-NB100-683-img0009.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/CD68-SR-D1-Antibody-(KP1)-Immunohistochemistry-NB100-683-img0009.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/CD68-SR-D1-Antibody-(KP1)-Immunohistochemistry-NB100-683-img0009.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/CD68-SR-D1-Antibody-(KP1)-Flow-Cytometry-NB100-683-img0004.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/CD68-SR-D1-Antibody-(KP1)-Flow-Cytometry-NB100-683-img0004.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/CD68-SR-D1-Antibody-(KP1)-Flow-Cytometry-NB100-683-img0004.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/CD68-SR-D1-Antibody-(KP1)-Flow-Cytometry-NB100-683-img0004.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/CD68-SR-D1-Antibody-(KP1)-Immunocytochemistry-Immunofluorescence-NB100-683-img0012.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/CD68-SR-D1-Antibody-(KP1)-Immunocytochemistry-Immunofluorescence-NB100-683-img0012.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/CD68-SR-D1-Antibody-(KP1)-Immunocytochemistry-Immunofluorescence-NB100-683-img0012.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/CD68-SR-D1-Antibody-(KP1)-Immunocytochemistry-Immunofluorescence-NB100-683-img0012.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/CD68-SR-D1-Antibody-(KP1)-Western-Blot-NB100-683-img0007.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/CD68-SR-D1-Antibody-(KP1)-Western-Blot-NB100-683-img0007.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/CD68-SR-D1-Antibody-(KP1)-Western-Blot-NB100-683-img0007.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/CD68-SR-D1-Antibody-(KP1)-Western-Blot-NB100-683-img0007.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/CD68-SR-D1-Antibody-(KP1)-Flow-Cytometry-NB100-683-img0013.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/CD68-SR-D1-Antibody-(KP1)-Flow-Cytometry-NB100-683-img0013.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/CD68-SR-D1-Antibody-(KP1)-Flow-Cytometry-NB100-683-img0013.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/CD68-SR-D1-Antibody-(KP1)-Flow-Cytometry-NB100-683-img0013.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/CD68-SR-D1-Antibody-(KP1)-Immunocytochemistry-Immunofluorescence-NB100-683-img0011.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/CD68-SR-D1-Antibody-(KP1)-Immunocytochemistry-Immunofluorescence-NB100-683-img0011.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/CD68-SR-D1-Antibody-(KP1)-Immunocytochemistry-Immunofluorescence-NB100-683-img0011.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/CD68-SR-D1-Antibody-(KP1)-Immunocytochemistry-Immunofluorescence-NB100-683-img0011.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/CD68-SR-D1-Antibody-(KP1)-Immunohistochemistry-Paraffin-NB100-683-img0006.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/CD68-SR-D1-Antibody-(KP1)-Immunohistochemistry-Paraffin-NB100-683-img0006.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/CD68-SR-D1-Antibody-(KP1)-Immunohistochemistry-Paraffin-NB100-683-img0006.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/CD68-SR-D1-Antibody-(KP1)-Immunohistochemistry-Paraffin-NB100-683-img0006.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/CD68-SR-D1-Antibody-(KP1)-Flow-Cytometry-NB100-683-img0005.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/CD68-SR-D1-Antibody-(KP1)-Flow-Cytometry-NB100-683-img0005.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/CD68-SR-D1-Antibody-(KP1)-Flow-Cytometry-NB100-683-img0005.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/CD68-SR-D1-Antibody-(KP1)-Flow-Cytometry-NB100-683-img0005.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/CD68-SR-D1-Antibody-(KP1)-Dual-RNAscope-ISH-IHC-NB100-683-img0010.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/CD68-SR-D1-Antibody-(KP1)-Dual-RNAscope-ISH-IHC-NB100-683-img0010.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/CD68-SR-D1-Antibody-(KP1)-Dual-RNAscope-ISH-IHC-NB100-683-img0010.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/CD68-SR-D1-Antibody-(KP1)-Dual-RNAscope-ISH-IHC-NB100-683-img0010.jpg
accessionNumbers :
P34810
applications :
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Electron Microscopy, Dual RNAscope ISH-IHC
extended description :
Clone KP1 was used by HLDA to establish CD designation.
USD :
429 USD
product details :
Clone KP1 was used by HLDA to establish CD designation.
alt names :
CD_antigen: CD68, CD68, CD68 antigen, CD68 molecule, DKFZp686M18236, GP110, LAMP4, macrophage antigen CD68, macrosialin, SCARD1, scavenger receptor class D, member 1
storage :
Store at 4C. Do not freeze.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.