product summary
Loading...
company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
PHF6 Antibody
catalog :
NB100-68262
quantity :
0.1 ml
price :
399 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunoprecipitation, chromatin immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, western blot knockout validation
more info or order :
citations: 13
Published Application/Species/Sample/DilutionReference
  • western blot knockout validation; human; fig 3b
Xiang J, Wang G, Xia T, Chen Z. The depletion of PHF6 decreases the drug sensitivity of T-cell acute lymphoblastic leukemia to prednisolone. Biomed Pharmacother. 2019;109:2210-2217 pubmed publisher
Oh S, Boo K, Kim J, Baek S, Jeon Y, You J, et al. The chromatin-binding protein PHF6 functions as an E3 ubiquitin ligase of H2BK120 via H2BK12Ac recognition for activation of trophectodermal genes. Nucleic Acids Res. 2020;48:9037-9052 pubmed publisher
Gan L, Sun J, Yang S, Zhang X, Chen W, Sun Y, et al. Chromatin-Binding Protein PHF6 Regulates Activity-Dependent Transcriptional Networks to Promote Hunger Response. Cell Rep. 2020;30:3717-3728.e6 pubmed publisher
Konno T, Kohno T, Kikuchi S, Shimada H, Satohisa S, Saito T, et al. Epithelial barrier dysfunction and cell migration induction via JNK/cofilin/actin by angubindin-1. Tissue Barriers. 2020;8:1695475 pubmed publisher
Konno T, Kohno T, Kikuchi S, Shimada H, Satohisa S, Takano K, et al. Localization of Tricellular Tight Junction Molecule LSR at Midbody and Centrosome During Cytokinesis in Human Epithelial Cells. J Histochem Cytochem. 2020;68:59-72 pubmed publisher
Warmerdam D, Alonso de Vega I, Wiegant W, van den Broek B, Rother M, Wolthuis R, et al. PHF6 promotes non-homologous end joining and G2 checkpoint recovery. EMBO Rep. 2019;:e48460 pubmed publisher
Cheng C, Deng P, Ikeuchi Y, Yuede C, Li D, Rensing N, et al. Characterization of a Mouse Model of Börjeson-Forssman-Lehmann Syndrome. Cell Rep. 2018;25:1404-1414.e6 pubmed publisher
Konno T, Takano K, Kaneko Y, Kakuki T, Nomura K, Yajima R, et al. Guanylate binding protein-1-mediated epithelial barrier in human salivary gland duct epithelium. Exp Cell Res. 2018;371:31-41 pubmed publisher
Shimada H, Satohisa S, Kohno T, Konno T, Takano K, Takahashi S, et al. Downregulation of lipolysis-stimulated lipoprotein receptor promotes cell invasion via claudin-1-mediated matrix metalloproteinases in human endometrial cancer. Oncol Lett. 2017;14:6776-6782 pubmed publisher
Takano K, Kakuki T, Kaneko Y, Kohno T, Kikuchi S, Himi T, et al. Histone deacetylase inhibition prevents cell death induced by loss of tricellular tight junction proteins in temperature-sensitive mouse cochlear cells. PLoS ONE. 2017;12:e0182291 pubmed publisher
Miyata R, Kakuki T, Nomura K, Ohkuni T, Ogasawara N, Takano K, et al. Poly(I:C) induced microRNA-146a regulates epithelial barrier and secretion of proinflammatory cytokines in human nasal epithelial cells. Eur J Pharmacol. 2015;761:375-82 pubmed publisher
Sohet F, Lin C, Munji R, Lee S, Ruderisch N, Soung A, et al. LSR/angulin-1 is a tricellular tight junction protein involved in blood-brain barrier formation. J Cell Biol. 2015;208:703-11 pubmed publisher
Meacham C, LAWTON L, Soto Feliciano Y, Pritchard J, Joughin B, Ehrenberger T, et al. A genome-scale in vivo loss-of-function screen identifies Phf6 as a lineage-specific regulator of leukemia cell growth. Genes Dev. 2015;29:483-8 pubmed publisher
product information
brand :
Novus
master code :
NB100-68262
SKU :
NB100-68262
product name :
PHF6 Antibody
description :
The PHF6 Antibody from NB100-68262 is a nb100-68262 antibody to . The PHF6 Antibody has been validated for the following applications: Q8IWS0.
target :
PHF6
category :
Primary Antibodies
unit sizes :
0.1 ml
buffer :
TBS and 0.1% BSA
clonality :
Polyclonal
concentration :
0.2 mg/ml
conjugate :
Unconjugated
host :
Rabbit
immunogen :
The immunogen recognized by this antibody maps to a region between residue 315 and 365 of human PHD finger protein 6 (NP_115834.1).
isotype :
IgG
purity :
Immunogen affinity purified
species :
Human, Mouse
theoretical molecular weight :
41.29 kDa
gene symbol :
PHF6
accessionNumbers :
Q8IWS0
applications :
Western Blot, Immunohistochemistry, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Chromatin Immunoprecipitation (ChIP)
USD :
399 USD
alt names :
BFLS, BORJ, Borjeson-Forssman-Lehmann syndrome, KIAA1823, MGC14797, PHD finger protein 6, PHD-like zinc finger protein
storage :
Store at 4C. Do not freeze.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.