product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
hnRNP A1 Antibody (4B10) - BSA Free
catalog :
NB100-672
quantity :
0.1 ml (also 0.025 ml)
price :
379 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
4B10
reactivity :
human, bovine
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation
more info or order :
citations: 38
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:2000; loading ...; fig s3b
Hu J, Khodadadi Jamayran A, Mao M, Shah K, Yang Z, Nasim M, et al. AKAP95 regulates splicing through scaffolding RNAs and RNA processing factors. Nat Commun. 2016;7:13347 pubmed publisher
  • western blot; human; loading ...; fig 2
Kamelgarn M, Chen J, Kuang L, Arenas A, Zhai J, Zhu H, et al. Proteomic analysis of FUS interacting proteins provides insights into FUS function and its role in ALS. Biochim Biophys Acta. 2016;1862:2004-14 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 7c
  • western blot; human; loading ...; fig 5b
Kunze M, Benz F, Brauß T, Lampe S, Weigand J, Braun J, et al. sST2 translation is regulated by FGF2 via an hnRNP A1-mediated IRES-dependent mechanism. Biochim Biophys Acta. 2016;1859:848-59 pubmed publisher
Zhou X, Wahane S, Friedl M, Kluge M, Friedel C, Avrampou K, et al. Microglia and macrophages promote corralling, wound compaction and recovery after spinal cord injury via Plexin-B2. Nat Neurosci. 2020;23:337-350 pubmed publisher
Clément T, Lee J, Ichkova A, Rodriguez Grande B, Fournier M, Aussudre J, et al. Juvenile mild traumatic brain injury elicits distinct spatiotemporal astrocyte responses. Glia. 2020;68:528-542 pubmed publisher
Patteson A, Pogoda K, Byfield F, Mandal K, Ostrowska Podhorodecka Z, Charrier E, et al. Loss of Vimentin Enhances Cell Motility through Small Confining Spaces. Small. 2019;15:e1903180 pubmed publisher
Ardalani H, Sengupta S, Harms V, Vickerman V, Thomson J, Murphy W. 3-D culture and endothelial cells improve maturity of human pluripotent stem cell-derived hepatocytes. Acta Biomater. 2019;95:371-381 pubmed publisher
Fang M, Markmiller S, Vu A, Javaherian A, Dowdle W, Jolivet P, et al. Small-Molecule Modulation of TDP-43 Recruitment to Stress Granules Prevents Persistent TDP-43 Accumulation in ALS/FTD. Neuron. 2019;: pubmed publisher
Marrone L, Drexler H, Wang J, Tripathi P, Distler T, Heisterkamp P, et al. FUS pathology in ALS is linked to alterations in multiple ALS-associated proteins and rescued by drugs stimulating autophagy. Acta Neuropathol. 2019;138:67-84 pubmed publisher
Casado Medrano V, Barrio Real L, Wang A, Cooke M, Lopez Haber C, Kazanietz M. Distinctive requirement of PKCε in the control of Rho GTPases in epithelial and mesenchymally transformed lung cancer cells. Oncogene. 2019;: pubmed publisher
Gasperini L, Rossi A, Cornella N, Peroni D, Zuccotti P, Potrich V, et al. The hnRNP raly regulates PRMT1 expression and interacts with the ALS-linked protein FUS: implication for reciprocal cellular localization. Mol Biol Cell. 2018;:mbcE18020108 pubmed publisher
Saxena M, Kalathur R, Neutzner M, Christofori G. PyMT-1099, a versatile murine cell model for EMT in breast cancer. Sci Rep. 2018;8:12123 pubmed publisher
Li D, Wang C, Li Z, Wang H, He J, Zhu J, et al. Nano-sized Al2O3 particle-induced autophagy reduces osteolysis in aseptic loosening of total hip arthroplasty by negative feedback regulation of RANKL expression in fibroblasts. Cell Death Dis. 2018;9:840 pubmed publisher
Li Q, Ingram L, Kim S, Beharry Z, Cooper J, Cai H. Paracrine Fibroblast Growth Factor Initiates Oncogenic Synergy with Epithelial FGFR/Src Transformation in Prostate Tumor Progression. Neoplasia. 2018;20:233-243 pubmed publisher
Lampe S, Kunze M, Scholz A, Brauß T, Winslow S, Simm S, et al. Identification of the TXNIP IRES and characterization of the impact of regulatory IRES trans-acting factors. Biochim Biophys Acta. 2018;: pubmed publisher
Hulin A, Anstine L, Kim A, Potter S, DeFalco T, Lincoln J, et al. Macrophage Transitions in Heart Valve Development and Myxomatous Valve Disease. Arterioscler Thromb Vasc Biol. 2018;38:636-644 pubmed publisher
Tocchio A, Durmus N, Sridhar K, Mani V, Coskun B, El Assal R, et al. Magnetically Guided Self-Assembly and Coding of 3D Living Architectures. Adv Mater. 2018;30: pubmed publisher
Mao L, Gao W, Chen S, Song Y, Song C, Zhou Z, et al. Epothilone B impairs functional recovery after spinal cord injury by increasing secretion of macrophage colony-stimulating factor. Cell Death Dis. 2017;8:e3162 pubmed publisher
Anstine L, Horne T, Horwitz E, Lincoln J. Contribution of Extra-Cardiac Cells in Murine Heart Valves is Age-Dependent. J Am Heart Assoc. 2017;6: pubmed publisher
Sui B, Hu C, Zheng C, Shuai Y, He X, Gao P, et al. Recipient Glycemic Micro-environments Govern Therapeutic Effects of Mesenchymal Stem Cell Infusion on Osteopenia. Theranostics. 2017;7:1225-1244 pubmed publisher
Calibasi Kocal G, G ven S, Foygel K, Goldman A, Chen P, Sengupta S, et al. Dynamic Microenvironment Induces Phenotypic Plasticity of Esophageal Cancer Cells Under Flow. Sci Rep. 2016;6:38221 pubmed publisher
Behrens J, Solga R, Ziemann A, Rastetter R, Berwanger C, Herrmann H, et al. Coronin 1C-free primary mouse fibroblasts exhibit robust rearrangements in the orientation of actin filaments, microtubules and intermediate filaments. Eur J Cell Biol. 2016;95:239-51 pubmed publisher
Nakamura R, Koshiba Takeuchi K, Tsuchiya M, Kojima M, Miyazawa A, Ito K, et al. Expression analysis of Baf60c during heart regeneration in axolotls and neonatal mice. Dev Growth Differ. 2016;58:367-82 pubmed publisher
Smith L, Hammers D, Sweeney H, Barton E. Increased collagen cross-linking is a signature of dystrophin-deficient muscle. Muscle Nerve. 2016;54:71-8 pubmed publisher
Lehoczky J, Tabin C. Lgr6 marks nail stem cells and is required for digit tip regeneration. Proc Natl Acad Sci U S A. 2015;112:13249-54 pubmed publisher
Ge X, Pettan Brewer C, Morton J, Carter K, Fatemi S, Rabinovitch P, et al. Mitochondrial catalase suppresses naturally occurring lung cancer in old mice. Pathobiol Aging Age Relat Dis. 2015;5:28776 pubmed publisher
Wong J, Chen L, Huang Y, Sehba F, Friedel R, Zou H. Attenuation of Cerebral Ischemic Injury in Smad1 Deficient Mice. PLoS ONE. 2015;10:e0136967 pubmed publisher
Morissette Martin P, Maux A, Laterreur V, Mayrand D, L Gagné V, Moulin V, et al. Enhancing repair of full-thickness excisional wounds in a murine model: Impact of tissue-engineered biological dressings featuring human differentiated adipocytes. Acta Biomater. 2015;22:39-49 pubmed publisher
Pócsai K, Kalman M. Glial and perivascular structures in the subfornical organ: distinguishing the shell and core. J Histochem Cytochem. 2015;63:367-83 pubmed publisher
Marcuzzo S, Bonanno S, Kapetis D, Barzago C, Cavalcante P, D Alessandro S, et al. Up-regulation of neural and cell cycle-related microRNAs in brain of amyotrophic lateral sclerosis mice at late disease stage. Mol Brain. 2015;8:5 pubmed publisher
Fujiya M, Konishi H, Mohamed Kamel M, Ueno N, Inaba Y, Moriichi K, et al. microRNA-18a induces apoptosis in colon cancer cells via the autophagolysosomal degradation of oncogenic heterogeneous nuclear ribonucleoprotein A1. Oncogene. 2014;33:4847-56 pubmed publisher
Huelga S, Vu A, Arnold J, Liang T, Liu P, Yan B, et al. Integrative genome-wide analysis reveals cooperative regulation of alternative splicing by hnRNP proteins. Cell Rep. 2012;1:167-78 pubmed
Lin Y, Yen P. A novel nucleocytoplasmic shuttling sequence of DAZAP1, a testis-abundant RNA-binding protein. RNA. 2006;12:1486-93 pubmed
Bonnal S, Pileur F, Orsini C, Parker F, Pujol F, Prats A, et al. Heterogeneous nuclear ribonucleoprotein A1 is a novel internal ribosome entry site trans-acting factor that modulates alternative initiation of translation of the fibroblast growth factor 2 mRNA. J Biol Chem. 2005;280:4144-53 pubmed
Pino I, Pio R, Toledo G, Zabalegui N, Vicent S, Rey N, et al. Altered patterns of expression of members of the heterogeneous nuclear ribonucleoprotein (hnRNP) family in lung cancer. Lung Cancer. 2003;41:131-43 pubmed
Guil S, Gattoni R, Carrascal M, Abian J, Stevenin J, Bach Elias M. Roles of hnRNP A1, SR proteins, and p68 helicase in c-H-ras alternative splicing regulation. Mol Cell Biol. 2003;23:2927-41 pubmed
Mili S, Shu H, Zhao Y, Pinol Roma S. Distinct RNP complexes of shuttling hnRNP proteins with pre-mRNA and mRNA: candidate intermediates in formation and export of mRNA. Mol Cell Biol. 2001;21:7307-19 pubmed
van der Houven van Oordt W, Diaz Meco M, Lozano J, Krainer A, Moscat J, Caceres J. The MKK(3/6)-p38-signaling cascade alters the subcellular distribution of hnRNP A1 and modulates alternative splicing regulation. J Cell Biol. 2000;149:307-16 pubmed
product information
brand :
Novus
master code :
NB100-672
SKU :
NB100-672
product name :
hnRNP A1 Antibody (4B10) - BSA Free
description :
The hnRNP A1 Antibody (4B10) - BSA Free from Novus Biologicals is a mouse monoclonal antibody to hnRNP A1. This antibody reacts with human, mouse, bovine, canine. The hnRNP A1 Antibody (4B10) - BSA Free has been validated for the following applications: Western Blot, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Microarray, Knockdown Validated.
target :
hnRNP A1
category :
Primary Antibodies
sizes available :
0.1 ml (also 0.025 ml)
buffer :
PBS
clonality :
Monoclonal
clone :
4B10
concentration :
1.0 mg/ml
conjugate :
Unconjugated
host :
Mouse
immunogen :
Full length partially purified human hnRNP A1. [UniProt# P09651]
isotype :
IgG2a
purity :
Protein G purified
species :
Human, Mouse, Bovine, Canine
specificity :
Does not react with hnRNP A2 or B
gene symbol :
HNRNPA1
accessionNumbers :
P09651
applications :
Western Blot, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Microarray, Knockdown Validated
USD :
356
USD 2023 :
379 USD
alt names :
Helix-destabilizing protein, heterogeneous nuclear ribonucleoprotein A1, heterogeneous nuclear ribonucleoprotein A1B protein, heterogeneous nuclear ribonucleoprotein B2 protein, heterogeneous nuclear ribonucleoprotein core protein A1, hnRNP A1, hnRNP core protein A1, hnRNPA1, hnRNP-A1, HNRPA1MGC102835, nuclear ribonucleoprotein particle A1 protein, single-strand DNA-binding protein UP1, Single-strand RNA-binding protein
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.