product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
VEGF Antibody (VG1) - BSA Free
catalog :
NB100-664
quantity :
0.1 mg (also 0.025 mg)
price :
429 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
VG1
reactivity :
human, mouse, rat, dogs
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 72
Published Application/Species/Sample/DilutionReference
  • western blot; mouse
Shao J, Zhang Y, Yang T, Qi J, Zhang L, Deng L. HIF-1α disturbs osteoblasts and osteoclasts coupling in bone remodeling by up-regulating OPG expression. In Vitro Cell Dev Biol Anim. 2015;51:808-14 pubmed publisher
  • immunohistochemistry - frozen section; rat
Tam J, Ko C, Lau K, To M, Kwok H, Chan Y, et al. A Chinese 2-herb formula (NF3) promotes hindlimb ischemia-induced neovascularization and wound healing of diabetic rats. J Diabetes Complications. 2014;28:436-47 pubmed publisher
  • western blot; rat
Fedorova L, Sodhi K, Gatto Weis C, Puri N, Hinds T, Shapiro J, et al. Peroxisome proliferator-activated receptor ? agonist, HPP593, prevents renal necrosis under chronic ischemia. PLoS ONE. 2013;8:e64436 pubmed publisher
  • immunocytochemistry; mouse
  • immunohistochemistry; mouse
Milanesi A, Lee J, Li Z, DA Sacco S, Villani V, Cervantes V, et al. ?-Cell regeneration mediated by human bone marrow mesenchymal stem cells. PLoS ONE. 2012;7:e42177 pubmed publisher
  • immunohistochemistry - paraffin section; mouse
Kunze D, Wuttig D, Kausch I, Blietz C, Blumhoff L, Burmeister Y, et al. Antisense-mediated inhibition of survivin, hTERT and VEGF in bladder cancer cells in vitro and in vivo. Int J Oncol. 2008;32:1049-56 pubmed
  • western blot; human
Ptaszynska M, Pendrak M, Bandle R, Stracke M, Roberts D. Positive feedback between vascular endothelial growth factor-A and autotaxin in ovarian cancer cells. Mol Cancer Res. 2008;6:352-63 pubmed publisher
  • immunohistochemistry - paraffin section; human
  • western blot; human
O Byrne K, Koukourakis M, Giatromanolaki A, Cox G, Turley H, Steward W, et al. Vascular endothelial growth factor, platelet-derived endothelial cell growth factor and angiogenesis in non-small-cell lung cancer. Br J Cancer. 2000;82:1427-32 pubmed
  • immunohistochemistry - paraffin section; human
  • ELISA; human
  • western blot; human
Turley H, Scott P, Watts V, Bicknell R, Harris A, Gatter K. Expression of VEGF in routinely fixed material using a new monoclonal antibody VG1. J Pathol. 1998;186:313-8 pubmed
  • immunohistochemistry; human
Giatromanolaki A, Koukourakis M, Kakolyris S, Turley H, O Byrne K, Scott P, et al. Vascular endothelial growth factor, wild-type p53, and angiogenesis in early operable non-small cell lung cancer. Clin Cancer Res. 1998;4:3017-24 pubmed
Li G, Li D, Wu C, Li S, Chen F, Li P, et al. Homocysteine-targeting compounds as a new treatment strategy for diabetic wounds via inhibition of the histone methyltransferase SET7/9. Exp Mol Med. 2022;54:988-998 pubmed publisher
Wu M, Yu Z, Matar D, Karvar M, Chen Z, Ng B, et al. Human Amniotic Membrane Promotes Angiogenesis in an Oxidative Stress Chronic Diabetic Murine Wound Model. Adv Wound Care (New Rochelle). 2022;: pubmed publisher
Chen Y, Chen S, Li T, Lin T, Chen C, Yen G. 4-Acetylantroquinonol B enhances cell death and inhibits autophagy by downregulating the PI3K/Akt/MDR1 pathway in gemcitabine-resistant pancreatic cancer cells. Oncol Lett. 2022;23:128 pubmed publisher
Jin Y, Pan Y, Zheng S, Liu Y, Xu J, Peng Y, et al. Inactivation of EGLN3 hydroxylase facilitates Erk3 degradation via autophagy and impedes lung cancer growth. Oncogene. 2022;41:1752-1766 pubmed publisher
Xiang X, Zhou L, Lin Z, Qu X, Chen Y, Xia H. Metformin regulates macrophage polarization via the Shh signaling pathway to improve pulmonary vascular development in bronchopulmonary dysplasia. IUBMB Life. 2022;74:259-271 pubmed publisher
Saleh T, El Sadoni M, Alhesa A, Awad H, Jaradat M, Al Hazaimeh M, et al. Expression of Senescence and Apoptosis Biomarkers in Synchronous Bilateral Breast Cancer: A Case Report. Curr Oncol. 2021;28:3836-3845 pubmed publisher
Li S, Li Y, Wu Z, Wu Z, Fang H. Diabetic ferroptosis plays an important role in triggering on inflammation in diabetic wound. Am J Physiol Endocrinol Metab. 2021;321:E509-E520 pubmed publisher
Doganlar O, Doganlar Z, Delen E, Doğan A. The role of melatonin in angio-miR-associated inhibition of tumorigenesis and invasion in human glioblastoma tumour spheroids. Tissue Cell. 2021;73:101617 pubmed publisher
Zhao Z, Li G, Ruan H, Chen K, Cai Z, Lu G, et al. Capturing Magnesium Ions via Microfluidic Hydrogel Microspheres for Promoting Cancellous Bone Regeneration. ACS Nano. 2021;: pubmed publisher
Zhu H, Chen D, Xie X, Li Y, Fan T. Melittin inhibits lung metastasis of human osteosarcoma: Evidence of wnt/β-catenin signaling pathway participation. Toxicon. 2021;198:132-142 pubmed publisher
Wang T, Zhang C, Xie H, Jiang M, Tian H, Lu L, et al. Anti-VEGF therapy prevents Müller intracellular edema by decreasing VEGF-A in diabetic retinopathy. Eye Vis (Lond). 2021;8:13 pubmed publisher
Akdaş Reis Y, Tapisiz O, Goktolga U, Sımşek G, Erten Ö, Kıykac Altınbaş S, et al. The Effect of Disulfiram in the Prevention of Postoperative Adhesion Formation in an Experimental Rat Uterine Horn Model. Reprod Sci. 2021;: pubmed publisher
Sene L, Scarano W, Zapparoli A, Gontijo J, Boer P. Impact of gestational low-protein intake on embryonic kidney microRNA expression and in nephron progenitor cells of the male fetus. PLoS ONE. 2021;16:e0246289 pubmed publisher
Bhattacharjee J, Mohammad S, Goudreau A, Adamo K. Physical activity differentially regulates VEGF, PlGF, and their receptors in the human placenta. Physiol Rep. 2021;9:e14710 pubmed publisher
Han X, Sun M, Chen B, Saiding Q, Zhang J, Song H, et al. Lotus seedpod-inspired internal vascularized 3D printed scaffold for bone tissue repair. Bioact Mater. 2021;6:1639-1652 pubmed publisher
Cho J, Kim T, Seok J, Jun J, Park H, Kweon M, et al. Vascular remodeling by placenta-derived mesenchymal stem cells restores ovarian function in ovariectomized rat model via the VEGF pathway. Lab Invest. 2021;101:304-317 pubmed publisher
So J, Lee J, Ahn Y, Kang D, Jung W, Bae W. The synergistic effect of biomimetic electrical stimulation and extracellular-matrix-mimetic nanopattern for upregulating cell activities. Biosens Bioelectron. 2020;167:112470 pubmed publisher
Liu D, Xu H, Zhang C, Xie H, Yang Q, Li W, et al. Erythropoietin maintains VE-cadherin expression and barrier function in experimental diabetic retinopathy via inhibiting VEGF/VEGFR2/Src signaling pathway. Life Sci. 2020;259:118273 pubmed publisher
Bombeiro A, Pereira B, Bonfanti A, Oliveira A. Immunomodulation by dimethyl fumarate treatment improves mouse sciatic nerve regeneration. Brain Res Bull. 2020;160:24-32 pubmed publisher
Patel C, Goody R, Hu W, Kurian A, James D, Torres R, et al. Primate model of chronic retinal neovascularization and vascular leakage. Exp Eye Res. 2020;195:108031 pubmed publisher
Mandell E, Ryan S, Seedorf G, Gonzalez T, Smith B, Fleet J, et al. Maternal Vitamin D Deficiency Causes Sustained Impairment of Lung Structure and Function and Increases Susceptibility to Hyperoxia-induced Lung Injury in Infant Rats. Am J Respir Cell Mol Biol. 2020;63:79-91 pubmed publisher
Chou P, Lin Y, Wu S, Lin S, Srinivasan P, Hsieh D, et al. Supercritical Carbon Dioxide-decellularized Porcine Acellular Dermal Matrix combined with Autologous Adipose-derived Stem Cells: Its Role in Accelerated Diabetic Wound Healing. Int J Med Sci. 2020;17:354-367 pubmed publisher
Li J, Zhou W, Chen W, Wang H, Zhang Y, Yu T. Mechanism of the hypoxia inducible factor 1/hypoxic response element pathway in rat myocardial ischemia/diazoxide post‑conditioning. Mol Med Rep. 2020;21:1527-1536 pubmed publisher
Gao L, Mei S, Zhang S, Qin Q, Li H, Liao Y, et al. Cardio-renal Exosomes in Myocardial Infarction Serum Regulate Proangiogenic Paracrine Signaling in Adipose Mesenchymal Stem Cells. Theranostics. 2020;10:1060-1073 pubmed publisher
Su C, Hsu T, Hsiao C, Chiu C, Tzang B. Effects of antibodies against human parvovirus B19 on angiogenic signaling. Mol Med Rep. 2020;21:1320-1327 pubmed publisher
Guo Q, Zhang Y, Zhang S, Jin J, Pang S, Wu X, et al. Genome-wide translational reprogramming of genes important for myocyte functions in overload-induced heart failure. Biochim Biophys Acta Mol Basis Dis. 2020;1866:165649 pubmed publisher
Wen G, Xu J, Wu T, Zhang S, Chai Y, Kang Q, et al. Functionalized Polycaprolactone/Hydroxyapatite Composite Microspheres for Promoting Bone Consolidation in a Rat Distraction Osteogenesis Model. J Orthop Res. 2020;38:961-971 pubmed publisher
Militi A, Cutroneo G, Favaloro A, Matarese G, Di Mauro D, Lauritano F, et al. An immunofluorescence study on VEGF and extracellular matrix proteins in human periodontal ligament during tooth movement. Heliyon. 2019;5:e02572 pubmed publisher
Lin Y, Chen R, Liang J, Hung Y, Yeh L, Chang W, et al. Immunohistochemical Biomarkers of Survival in Patients With Adenocarcinoma of the Uterine Cervix Receiving Chemoradiotherapy. Anticancer Res. 2019;39:3231-3240 pubmed publisher
Saito H, Tanaka K, Fujiwara M, Iwasaki T, Numata T, Oda A, et al. Pathological findings of progressive renal involvement in a patient with TAFRO syndrome. CEN Case Rep. 2019;: pubmed publisher
Dewangan J, Srivastava S, Mishra S, Divakar A, Kumar S, Rath S. Salinomycin inhibits breast cancer progression via targeting HIF-1α/VEGF mediated tumor angiogenesis in vitro and in vivo. Biochem Pharmacol. 2019;164:326-335 pubmed publisher
Jarman E, Ward C, Turnbull A, Martinez Perez C, Meehan J, Xintaropoulou C, et al. HER2 regulates HIF-2α and drives an increased hypoxic response in breast cancer. Breast Cancer Res. 2019;21:10 pubmed publisher
Shen W, Lee S, Yam M, Zhu L, Zhang T, Pye V, et al. A Combination Therapy Targeting Endoglin and VEGF-A Prevents Subretinal Fibro-Neovascularization Caused by Induced Müller Cell Disruption. Invest Ophthalmol Vis Sci. 2018;59:6075-6088 pubmed publisher
Yan Y, Chen H, Zhang H, Guo C, Yang K, Chen K, et al. Vascularized 3D printed scaffolds for promoting bone regeneration. Biomaterials. 2018;190-191:97-110 pubmed publisher
Chen Y, Gao S, Yan Y, Qian J, Chen H. Aerosolized deferoxamine administration in mouse model of bronchopulmonary dysplasia improve pulmonary development. Am J Transl Res. 2018;10:325-332 pubmed
Wang C, Wang Q, Gao W, Zhang Z, Lou Y, Jin H, et al. Highly efficient local delivery of endothelial progenitor cells significantly potentiates angiogenesis and full-thickness wound healing. Acta Biomater. 2018;69:156-169 pubmed publisher
Xu J, Sun Y, Wu T, Liu Y, Shi L, Zhang J, et al. Enhancement of bone regeneration with the accordion technique via HIF-1α/VEGF activation in a rat distraction osteogenesis model. J Tissue Eng Regen Med. 2018;12:e1268-e1276 pubmed publisher
Farjood F, Vargis E. Physical disruption of cell-cell contact induces VEGF expression in RPE cells. Mol Vis. 2017;23:431-446 pubmed
Li H, Yang S, Yu G, Shen L, Fan J, Xu L, et al. Aptamer Internalization via Endocytosis Inducing S-Phase Arrest and Priming Maver-1 Lymphoma Cells for Cytarabine Chemotherapy. Theranostics. 2017;7:1204-1213 pubmed publisher
Du C, Mendelson A, Guan Q, Dairi G, Chafeeva I, da Roza G, et al. Hyperbranched polyglycerol is superior to glucose for long-term preservation of peritoneal membrane in a rat model of chronic peritoneal dialysis. J Transl Med. 2016;14:338 pubmed
Lin Y, Chen R, Chen S, Hsieh T, Yen K, Liang J, et al. Immunohistochemical studies and fluorodeoxyglucose uptake on positron emission tomography in pharyngeal cancer for predicting radiotherapy-based treatment outcomes. Clin Otolaryngol. 2017;42:608-619 pubmed publisher
Su J, Mar A, Wu S, Tai W, Chu P, Wu C, et al. Disrupting VEGF-A paracrine and autocrine loops by targeting SHP-1 suppresses triple negative breast cancer metastasis. Sci Rep. 2016;6:28888 pubmed publisher
Chen S, Lin Y, Chen R, Hsieh T, Yen K, Liang J, et al. Immunohistochemical overexpression of hypoxia-induced factor 1? associated with slow reduction in 18fluoro-2-deoxy-D-glucose uptake for chemoradiotherapy in patients with pharyngeal cancer. Eur J Nucl Med Mol Imaging. 2016;43:2343-2352 pubmed
Chen H, Jia P, Kang H, Zhang H, Liu Y, Yang P, et al. Upregulating Hif-1α by Hydrogel Nanofibrous Scaffolds for Rapidly Recruiting Angiogenesis Relative Cells in Diabetic Wound. Adv Healthc Mater. 2016;5:907-18 pubmed publisher
Ram M, Singh V, Kumawat S, Kant V, Tandan S, Kumar D. Bilirubin modulated cytokines, growth factors and angiogenesis to improve cutaneous wound healing process in diabetic rats. Int Immunopharmacol. 2016;30:137-149 pubmed publisher
Srinivas C, Ramaiah M, Lavanya A, Yerramsetty S, Kavi Kishor P, Basha S, et al. Novel Etoposide Analogue Modulates Expression of Angiogenesis Associated microRNAs and Regulates Cell Proliferation by Targeting STAT3 in Breast Cancer. PLoS ONE. 2015;10:e0142006 pubmed publisher
André H, Tunik S, Aronsson M, Kvanta A. Hypoxia-Inducible Factor-1α Is Associated With Sprouting Angiogenesis in the Murine Laser-Induced Choroidal Neovascularization Model. Invest Ophthalmol Vis Sci. 2015;56:6591-604 pubmed publisher
Ram M, Singh V, Kumawat S, Kumar D, Lingaraju M, Uttam Singh T, et al. Deferoxamine modulates cytokines and growth factors to accelerate cutaneous wound healing in diabetic rats. Eur J Pharmacol. 2015;764:9-21 pubmed publisher
Parlakgumus H, Aka Bolat F, Bulgan Kilicdag E, Simsek E, Parlakgumus A. Atorvastatin for ovarian torsion: effects on follicle counts, AMH, and VEGF expression. Eur J Obstet Gynecol Reprod Biol. 2014;175:186-90 pubmed publisher
Johansen F, Hasseldam H, Rasmussen R, Bisgaard A, Bonfils P, Poulsen S, et al. Drug-induced hypothermia as beneficial treatment before and after cerebral ischemia. Pathobiology. 2014;81:42-52 pubmed publisher
Hong D, Kurzrock R, Oh Y, Wheler J, Naing A, Brail L, et al. A phase 1 dose escalation, pharmacokinetic, and pharmacodynamic evaluation of eIF-4E antisense oligonucleotide LY2275796 in patients with advanced cancer. Clin Cancer Res. 2011;17:6582-91 pubmed publisher
Van der Auwera I, Van Laere S, Van den Eynden G, Benoy I, Van Dam P, Colpaert C, et al. Increased angiogenesis and lymphangiogenesis in inflammatory versus noninflammatory breast cancer by real-time reverse transcriptase-PCR gene expression quantification. Clin Cancer Res. 2004;10:7965-71 pubmed
Couvelard A, O Toole D, Turley H, Leek R, Sauvanet A, Degott C, et al. Microvascular density and hypoxia-inducible factor pathway in pancreatic endocrine tumours: negative correlation of microvascular density and VEGF expression with tumour progression. Br J Cancer. 2005;92:94-101 pubmed
Giatromanolaki A, Koukourakis M, Simopoulos C, Polychronidis A, Sivridis E. Vascular endothelial growth factor (VEGF) expression in operable gallbladder carcinomas. Eur J Surg Oncol. 2003;29:879-83 pubmed
Kapsoritakis A, Sfiridaki A, Maltezos E, Simopoulos K, Giatromanolaki A, Sivridis E, et al. Vascular endothelial growth factor in inflammatory bowel disease. Int J Colorectal Dis. 2003;18:418-22 pubmed
Giatromanolaki A, Koukourakis M, Sivridis E, Turley H, Wykoff C, Gatter K, et al. DEC1 (STRA13) protein expression relates to hypoxia- inducible factor 1-alpha and carbonic anhydrase-9 overexpression in non-small cell lung cancer. J Pathol. 2003;200:222-8 pubmed
Giatromanolaki A, Sivridis E, Maltezos E, Papazoglou D, Simopoulos C, Gatter K, et al. Hypoxia inducible factor 1alpha and 2alpha overexpression in inflammatory bowel disease. J Clin Pathol. 2003;56:209-13 pubmed
Salgado R, Benoy I, Weytjens R, Van Bockstaele D, Van Marck E, Huget P, et al. Arterio-venous gradients of IL-6, plasma and serum VEGF and D-dimers in human cancer. Br J Cancer. 2002;87:1437-44 pubmed
Zhang H, Scott P, Morbidelli L, Peak S, Moore J, Turley H, et al. The 121 amino acid isoform of vascular endothelial growth factor is more strongly tumorigenic than other splice variants in vivo. Br J Cancer. 2000;83:63-8 pubmed
Koukourakis M, Giatromanolaki A, Thorpe P, Brekken R, Sivridis E, Kakolyris S, et al. Vascular endothelial growth factor/KDR activated microvessel density versus CD31 standard microvessel density in non-small cell lung cancer. Cancer Res. 2000;60:3088-95 pubmed
Adams J, Carder P, Downey S, Forbes M, MacLennan K, Allgar V, et al. Vascular endothelial growth factor (VEGF) in breast cancer: comparison of plasma, serum, and tissue VEGF and microvessel density and effects of tamoxifen. Cancer Res. 2000;60:2898-905 pubmed
Giatromanolaki A, Koukourakis M, Sivridis E, O Byrne K, Cox G, Thorpe P, et al. Coexpression of MUC1 glycoprotein with multiple angiogenic factors in non-small cell lung cancer suggests coactivation of angiogenic and migration pathways. Clin Cancer Res. 2000;6:1917-21 pubmed
Kakolyris S, Giatromanolaki A, Koukourakis M, Leigh I, Georgoulias V, Kanavaros P, et al. Assessment of vascular maturation in non-small cell lung cancer using a novel basement membrane component, LH39: correlation with p53 and angiogenic factor expression. Cancer Res. 1999;59:5602-7 pubmed
product information
brand :
Novus
master code :
NB100-664
SKU :
NB100-664
product name :
VEGF Antibody (VG1) - BSA Free
description :
The VEGF Antibody (VG1) - BSA Free from Novus Biologicals is a mouse monoclonal antibody to VEGF. This antibody reacts with human, mouse, rat, porcine, canine. The VEGF Antibody (VG1) - BSA Free has been validated for the following applications: Western Blot, Simple Western, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, CyTOF-ready.
target :
VEGF
category :
Primary Antibodies
sizes available :
0.1 mg (also 0.025 mg)
buffer :
PBS
clonality :
Monoclonal
clone :
VG1
concentration :
1 mg/ml
conjugate :
Unconjugated
host :
Mouse
immunogen :
Recombinant VEGF 189 protein.
isotype :
IgG1 Kappa
purity :
Protein G purified
species :
Human, Mouse, Rat, Porcine, Canine
specificity :
This VEGF Antibody (VG1) detects the 189, 165 and 121 isoforms of VEGF
gene symbol :
VEGFA
accessionNumbers :
P15692
applications :
Western Blot, Simple Western, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, CyTOF-ready
USD :
410
USD 2023 :
429 USD
alt names :
MVCD1, vascular endothelial growth factor A, Vascular permeability factor, VEGF-A, VEGFMGC70609, VPFvascular endothelial growth factor
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.