CD8 Antibody (4B11) | Novus Biologicals NB100-65729 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

CD8 Antibody (4B11)

catalog :

NB100-65729

quantity :

0.1 ml (also 0.025 ml)

price :

409 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

4B11

reactivity :

human

application :

immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Novus Biologicals product webpage

citations: 6

Reference
Chimote A, Gawali V, Newton H, Wise Draper T, Conforti L. A Compartmentalized Reduction in Membrane-Proximal Calmodulin Reduces the Immune Surveillance Capabilities of CD8+ T Cells in Head and Neck Cancer. Front Pharmacol. 2020;11:143 pubmed publisher
Soh J, Jo S, Lee H, Do E, Hwang S, Park S, et al. Immunoprofiling of Colitis-associated and Sporadic Colorectal Cancer and its Clinical Significance. Sci Rep. 2019;9:6833 pubmed publisher
Park I, An S, Kim S, Lim H, Hong S, Kim M, et al. Prediction of radio-responsiveness with immune-profiling in patients with rectal cancer. Oncotarget. 2017;8:79793-79802 pubmed publisher
Cao Y, Wang X, Xu C, Gao Z, Zhou H, Wang Y, et al. 4-HPR impairs bladder cancer cell migration and invasion by interfering with the Wnt5a/JNK and Wnt5a/MMP-2 signaling pathways. Oncol Lett. 2016;12:1833-1839 pubmed
Monteiro da Rocha A, Ding J, Slawny N, Wolf A, Smith G. Loss of glycogen synthase kinase 3 isoforms during murine oocyte growth induces offspring cardiac dysfunction. Biol Reprod. 2015;92:127 pubmed publisher
van Esch E, van Poelgeest M, Kouwenberg S, Osse E, Trimbos J, Fleuren G, et al. Expression of coinhibitory receptors on T cells in the microenvironment of usual vulvar intraepithelial neoplasia is related to proinflammatory effector T cells and an increased recurrence-free survival. Int J Cancer. 2015;136:E95-106 pubmed publisher

product information

brand :

Novus Biologicals, a Bio-Techne brand

catalog number base :

NB100-65729

SKU :

NB100-65729

product name :

CD8 Antibody (4B11)

description :

The CD8 Antibody (4B11) from Novus Biologicals is a mouse monoclonal antibody to CD8. This antibody reacts with human. The CD8 Antibody (4B11) has been validated for the following applications: Immunohistochemistry,Immunohistochemistry-Frozen,Dual RNAscope ISH-IHC,Immunohistochemistry-Paraffin,Immunofluorescence.

target :

CD8

unit size :

0.1 ml (also 0.025 ml)

category :

Primary Antibodies

buffer :

Tissue culture supernatant

clonality :

Monoclonal

clone :

4B11

conjugate :

Unconjugated

host :

Mouse

immunogen :

Synthetic peptide derived from the carboxy terminal region of the human CD8 alpha chain coupled to a N-terminal cysteine, with the sequence C-KSDGKPSLSARYV. The peptide was coupled to bovine serum albumin and keyhole limpet hemocyanin

isotype :

IgG2b

purity :

Tissue culture supernatant

species :

Human

specificity :

CD8 Antibody (4B11) recognizes the human CD8 cell surface antigen, a 32kD glycoprotein expressed by the cytotoxic/suppressor subset of T-cells and weakly by NK cells

storage :

Store at 4C. Do not freeze.

theoretical molecular weight :

26 kDa

gene symbol :

CD8A

Antibody validation :

Orthogonal Validation

accessionNumbers :

P01732

applications :

Immunohistochemistry,Immunohistochemistry-Frozen,Dual RNAscope ISH-IHC,Immunohistochemistry-Paraffin,Immunofluorescence

USD :

399

USD 2025 :

409 USD

alt names :

CD_antigen: CD8a, CD8, CD8 antigen, alpha polypeptide (p32), CD8A, CD8a molecule, LEU2, Leu2 T-lymphocyte antigen, MAL, OKT8 T-cell antigen, p32, T cell co-receptor, T8 T-cell antigen, T-cell antigen Leu2, T-cell surface glycoprotein CD8 alpha chain, T-lymphocyte differentiation antigen T8/Leu-2

more info or order :

Novus Biologicals product webpage