MHC Class II RT1B Antibody (OX-6) | Novus Biologicals NB100-65541 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

MHC Class II RT1B Antibody (OX-6)

catalog :

NB100-65541

quantity :

0.25 mg (also 0.05 mg)

price :

329 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

OX-6

reactivity :

mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Novus Biologicals product webpage

citations: 25

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; mouse; loading ...; fig s9	Safaiyan S, Kannaiyan N, Snaidero N, Brioschi S, Biber K, Yona S, et al. Age-related myelin degradation burdens the clearance function of microglia during aging. Nat Neurosci. 2016;19:995-8 pubmed publisher
	Kingsbury C, Shear A, Heyck M, Sadanandan N, Zhang H, Gonzales Portillo B, et al. Inflammation-relevant microbiome signature of the stroke brain, gut, spleen, and thymus and the impact of exercise. J Cereb Blood Flow Metab. 2021;41:3200-3212 pubmed publisher
	Lee J, Tuazon J, Corey S, Bonsack B, Acosta S, Ehrhart J, et al. A Gutsy Move for Cell-Based Regenerative Medicine in Parkinson's Disease: Targeting the Gut Microbiome to Sequester Inflammation and Neurotoxicity. Stem Cell Rev Rep. 2019;15:690-702 pubmed publisher
	Lee J, Tuazon J, Ehrhart J, Sanberg P, Borlongan C. Gutting the brain of inflammation: A key role of gut microbiome in human umbilical cord blood plasma therapy in Parkinson's disease model. J Cell Mol Med. 2019;23:5466-5474 pubmed publisher
	Miikkulainen P, Högel H, Seyednasrollah F, Rantanen K, Elo L, Jaakkola P. Hypoxia-inducible factor (HIF)-prolyl hydroxylase 3 (PHD3) maintains high HIF2A mRNA levels in clear cell renal cell carcinoma. J Biol Chem. 2019;294:3760-3771 pubmed publisher
	Pan H, Strickland A, Madhu V, Johnson Z, Chand S, Brody J, et al. RNA binding protein HuR regulates extracellular matrix gene expression and pH homeostasis independent of controlling HIF-1α signaling in nucleus pulposus cells. Matrix Biol. 2019;77:23-40 pubmed publisher
	Yano H, Sakai M, Matsukawa T, Yagi T, Naganuma T, Mitsushima M, et al. PHD3 regulates glucose metabolism by suppressing stress-induced signalling and optimising gluconeogenesis and insulin signalling in hepatocytes. Sci Rep. 2018;8:14290 pubmed publisher
	Akat F, Ficicilar H, Durak A, Tuncay E, Dursun A, Topal Celikkan F, et al. Intermittent hypoxia induces beneficial cardiovascular remodeling in left ventricular function of type 1 diabetic rat. Anatol J Cardiol. 2018;19:259-266 pubmed publisher
	Bryant J, Brown M, Dobrikov M, Dobrikova E, Gemberling S, Zhang Q, et al. Regulation of Hypoxia-Inducible Factor 1α during Hypoxia by DAP5-Induced Translation of PHD2. Mol Cell Biol. 2018;38: pubmed publisher
	Barreto Vianna A, Aguila M, Mandarim de Lacerda C. Beneficial effects of liraglutide (GLP1 analog) in the hippocampal inflammation. Metab Brain Dis. 2017;32:1735-1745 pubmed publisher
	Miikkulainen P, Högel H, Rantanen K, Suomi T, Kouvonen P, Elo L, et al. HIF prolyl hydroxylase PHD3 regulates translational machinery and glucose metabolism in clear cell renal cell carcinoma. Cancer Metab. 2017;5:5 pubmed publisher
	Oh S, Jorgensen M, Wasserfall C, Gjymishka A, Petersen B. Suppression of islet homeostasis protein thwarts diabetes mellitus progression. Lab Invest. 2017;97:577-590 pubmed publisher
	Bruno T, Valerio M, Casadei L, De Nicola F, Goeman F, Pallocca M, et al. Che-1 sustains hypoxic response of colorectal cancer cells by affecting Hif-1Î± stabilization. J Exp Clin Cancer Res. 2017;36:32 pubmed publisher
	Oh E, Kim J, Kim J, Kim S, Lee J, Hong S, et al. NQO1 inhibits proteasome-mediated degradation of HIF-1α. Nat Commun. 2016;7:13593 pubmed publisher
	Barnes E, Chen C, Sedan O, Cornfield D. Loss of smooth muscle cell hypoxia inducible factor-1? underlies increased vascular contractility in pulmonary hypertension. FASEB J. 2017;31:650-662 pubmed publisher
	Adam M, Matt S, Christian S, Hess Stumpp H, Haegebarth A, Hofmann T, et al. SIAH ubiquitin ligases regulate breast cancer cell migration and invasion independent of the oxygen status. Cell Cycle. 2015;14:3734-47 pubmed publisher
	Iriondo O, RÃ¡bano M, Domenici G, Carlevaris O, LÃ³pez Ruiz J, Zabalza I, et al. Distinct breast cancer stem/progenitor cell populations require either HIF1Î± or loss of PHD3 to expand under hypoxic conditions. Oncotarget. 2015;6:31721-39 pubmed publisher
	HÃ¶gel H, Miikkulainen P, Bino L, Jaakkola P. Hypoxia inducible prolyl hydroxylase PHD3 maintains carcinoma cell growth by decreasing the stability of p27. Mol Cancer. 2015;14:143 pubmed publisher
	Li J, Yuan W, Jiang S, Ye W, Yang H, Shapiro I, et al. Prolyl-4-hydroxylase domain protein 2 controls NF-ÎºB/p65 transactivation and enhances the catabolic effects of inflammatory cytokines on cells of the nucleus pulposus. J Biol Chem. 2015;290:7195-207 pubmed publisher
	Vogler M, Zieseniss A, Hesse A, Levent E, Tiburcy M, Heinze E, et al. Pre- and post-conditional inhibition of prolyl-4-hydroxylase domain enzymes protects the heart from an ischemic insult. Pflugers Arch. 2015;467:2141-9 pubmed publisher
	Ling Z, Zhu Y, Tong C, Snyder J, Lipton J, Carvey P. Prenatal lipopolysaccharide does not accelerate progressive dopamine neuron loss in the rat as a result of normal aging. Exp Neurol. 2009;216:312-20 pubmed publisher
	Couty J, Rampon C, Leveque M, Laran Chich M, Bourdoulous S, Greenwood J, et al. PECAM-1 engagement counteracts ICAM-1-induced signaling in brain vascular endothelial cells. J Neurochem. 2007;103:793-801 pubmed
	Ling Z, Zhu Y, Tong C, Snyder J, Lipton J, Carvey P. Progressive dopamine neuron loss following supra-nigral lipopolysaccharide (LPS) infusion into rats exposed to LPS prenatally. Exp Neurol. 2006;199:499-512 pubmed
	Carvey P, Zhao C, Hendey B, Lum H, Trachtenberg J, Desai B, et al. 6-Hydroxydopamine-induced alterations in blood-brain barrier permeability. Eur J Neurosci. 2005;22:1158-68 pubmed
	Ling Z, Chang Q, Tong C, Leurgans S, Lipton J, Carvey P. Rotenone potentiates dopamine neuron loss in animals exposed to lipopolysaccharide prenatally. Exp Neurol. 2004;190:373-83 pubmed

product information

brand :

Novus

master code :

NB100-65541

SKU :

NB100-65541

product name :

MHC Class II RT1B Antibody (OX-6)

description :

The MHC Class II RT1B Antibody (OX-6) from NB100-65541 is a nb100-65541 antibody to .

target :

MHC Class II RT1B

category :

Primary Antibodies

unit sizes :

0.25 mg (also 0.05 mg)

buffer :

PBS

clonality :

Monoclonal

clone :

OX-6

concentration :

1.0 mg/ml

conjugate :

Unconjugated

host :

Mouse

immunogen :

Rat thymocyte membrane glycoproteins

isotype :

IgG1

purity :

Protein G purified

species :

Mouse, Rat

specificity :

NB100-65541 recognizes a monomorphic determinant of the rat I-A antigen present on B lymphocytes, dendritic cells, some macrophages and certain epithelial cells

gene symbol :

RT1-B

applications :

Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Immunohistochemistry Free-Floating, CyTOF-ready

USD :

329 USD

alt names :

anti-OX-6 RT1B, anti-RT1B OX-6, Clone OX6, DMA, DMB, DP beta 1, DPB 1, DPB1, DRB, HLA class II histocompatibility antigen DM beta chain, HLA DMB, HLA DPB1, HLADM, HLADP1B, Major histocompatibility complex class II, Major histocompatibility complex class II DP beta 1, MHC class II antigen DMB, MHC class II DQ, MHC DPB1, Non-polymorphic MHC Class II, RING6, RING7, RT1B

storage :

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

more info or order :

Novus Biologicals product webpage