| Published Application/Species/Sample/Dilution | Reference |
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- western blot; mouse; 1:200; loading ...; fig 3a
| Bouchard G, Therriault H, Geha S, Bujold R, Saucier C, Paquette B. Radiation-induced lung metastasis development is MT1-MMP-dependent in a triple-negative breast cancer mouse model. Br J Cancer. 2017;116:479-488 pubmed publisher |
| Liu L, Chen M, Lin K, Xiang X, Zheng Y, Zhu S. Inhibiting Caspase-12 Mediated Inflammasome Activation protects against Oxygen-Glucose Deprivation Injury in Primary Astrocytes. Int J Med Sci. 2020;17:1936-1945 pubmed publisher |
| Pan H, Lin Y, Dou J, Fu Z, Yao Y, Ye S, et al. Wedelolactone facilitates Ser/Thr phosphorylation of NLRP3 dependent on PKA signalling to block inflammasome activation and pyroptosis. Cell Prolif. 2020;:e12868 pubmed publisher |
| Xie W, Ding J, Xie X, Yang X, Wu X, Chen Z, et al. Hepatitis B virus X protein promotes liver cell pyroptosis under oxidative stress through NLRP3 inflammasome activation. Inflamm Res. 2020;69:683-696 pubmed publisher |
| Dang S, Zhang Z, LI K, Zheng J, Qian L, Liu X, et al. Blockade of β-adrenergic signaling suppresses inflammasome and alleviates cardiac fibrosis. Ann Transl Med. 2020;8:127 pubmed publisher |
| Strassheim D, Karoor V, Nijmeh H, Weston P, Lapel M, Schaack J, et al. c-Jun, Foxo3a, and c-Myc Transcription Factors are Key Regulators of ATP-Mediated Angiogenic Responses in Pulmonary Artery Vasa Vasorum Endothelial Cells. Cells. 2020;9: pubmed publisher |
| Chueh T, Cheng Y, Chen K, Chien C. Thromboxane A2 Synthase and Thromboxane Receptor Deletion Reduces Ischaemia/Reperfusion-Evoked Inflammation, Apoptosis, Autophagy and Pyroptosis. Thromb Haemost. 2020;120:329-343 pubmed publisher |
| Madsen P, Desu H, de Rivero Vaccari J, Florimon Y, Ellman D, Keane R, et al. Oligodendrocytes modulate the immune-inflammatory response in EAE via TNFR2 signaling. Brain Behav Immun. 2020;84:132-146 pubmed publisher |
| Wang J, Li R, Peng Z, Hu B, Rao X, Li J. HMGB1 participates in LPS‑induced acute lung injury by activating the AIM2 inflammasome in macrophages and inducing polarization of M1 macrophages via TLR2, TLR4, and RAGE/NF‑κB signaling pathways. Int J Mol Med. 2020;45:61-80 pubmed publisher |
| Pereira C, Carlos D, Ferreira N, Silva J, Zanotto C, Zamboni D, et al. Mitochondrial DNA Promotes NLRP3 Inflammasome Activation and Contributes to Endothelial Dysfunction and Inflammation in Type 1 Diabetes. Front Physiol. 2019;10:1557 pubmed publisher |
| Gericke A, Mann C, Zadeh J, Musayeva A, Wolff I, Wang M, et al. Elevated Intraocular Pressure Causes Abnormal Reactivity of Mouse Retinal Arterioles. Oxid Med Cell Longev. 2019;2019:9736047 pubmed publisher |
| Köse Vogel N, Stengel S, Gardey E, Kirchberger Tolstik T, Reuken P, Stallmach A, et al. Transcriptional Suppression of the NLRP3 Inflammasome and Cytokine Release in Primary Macrophages by Low-Dose Anthracyclines. Cells. 2019;9: pubmed publisher |
| Ferreira N, Bruder Nascimento T, Pereira C, Zanotto C, Prado D, Silva J, et al. NLRP3 Inflammasome and Mineralocorticoid Receptors Are Associated with Vascular Dysfunction in Type 2 Diabetes Mellitus. Cells. 2019;8: pubmed publisher |
| Fais R, Rodrigues F, Pereira C, Mendes A, Mestriner F, Tostes R, et al. The inflammasome NLRP3 plays a dual role on mouse corpora cavernosa relaxation. Sci Rep. 2019;9:16224 pubmed publisher |
| Li Y, Su Y, Zhou T, Hu Z, Wei J, Wang W, et al. Activation of the NLRP3 Inflammasome Pathway by Prokineticin 2 in Testicular Macrophages of Uropathogenic Escherichia coli- Induced Orchitis. Front Immunol. 2019;10:1872 pubmed publisher |
| Frew J, Hawkes J, Krueger J. A systematic review and critical evaluation of immunohistochemical associations in hidradenitis suppurativa. F1000Res. 2018;7:1923 pubmed publisher |
| Zadeh J, Ruemmler R, Hartmann E, Ziebart A, Ludwig M, Patzak A, et al. Responses of retinal arterioles and ciliary arteries in pigs with acute respiratory distress syndrome (ARDS). Exp Eye Res. 2019;184:152-161 pubmed publisher |
| Pronin A, Pham D, An W, Dvoriantchikova G, Reshetnikova G, Qiao J, et al. Inflammasome Activation Induces Pyroptosis in the Retina Exposed to Ocular Hypertension Injury. Front Mol Neurosci. 2019;12:36 pubmed publisher |
| Mejias N, Martinez C, Stephens M, de Rivero Vaccari J. Contribution of the inflammasome to inflammaging. J Inflamm (Lond). 2018;15:23 pubmed publisher |
| Serganova I, Cohen I, Vemuri K, Shindo M, Maeda M, Mane M, et al. LDH-A regulates the tumor microenvironment via HIF-signaling and modulates the immune response. PLoS ONE. 2018;13:e0203965 pubmed publisher |
| Kerr N, Garcia Contreras M, Abbassi S, Mejias N, Desousa B, Ricordi C, et al. Inflammasome Proteins in Serum and Serum-Derived Extracellular Vesicles as Biomarkers of Stroke. Front Mol Neurosci. 2018;11:309 pubmed publisher |
| Raval A, Schatz M, Bhattacharya P, d Adesky N, Rundek T, Dietrich W, et al. Whole Body Vibration Therapy after Ischemia Reduces Brain Damage in Reproductively Senescent Female Rats. Int J Mol Sci. 2018;19: pubmed publisher |
| Furuya M, Asano T, Sumichika Y, Sato S, Kobayashi H, Watanabe H, et al. Tofacitinib inhibits granulocyte-macrophage colony-stimulating factor-induced NLRP3 inflammasome activation in human neutrophils. Arthritis Res Ther. 2018;20:196 pubmed publisher |
| d Adesky N, de Rivero Vaccari J, Bhattacharya P, Schatz M, Perez Pinzon M, Bramlett H, et al. Nicotine Alters Estrogen Receptor-Beta-Regulated Inflammasome Activity and Exacerbates Ischemic Brain Damage in Female Rats. Int J Mol Sci. 2018;19: pubmed publisher |
| Chen D, Chen Y, Chen H, Hsieh C, Gung N, Hung W, et al. Human parvovirus B19 nonstructural protein NS1 activates NLRP3 inflammasome signaling in adult‑onset Still's disease. Mol Med Rep. 2018;17:3364-3371 pubmed publisher |
| Fleetwood A, Lee M, Singleton W, Achuthan A, Lee M, O Brien Simpson N, et al. Metabolic Remodeling, Inflammasome Activation, and Pyroptosis in Macrophages Stimulated by Porphyromonas gingivalis and Its Outer Membrane Vesicles. Front Cell Infect Microbiol. 2017;7:351 pubmed publisher |
| Knudsen E, Balaji U, Freinkman E, McCue P, Witkiewicz A. Unique metabolic features of pancreatic cancer stroma: relevance to the tumor compartment, prognosis, and invasive potential. Oncotarget. 2016;7:78396-78411 pubmed publisher |
| Lévesque S, Paré A, Mailhot B, Bellver Landete V, Kébir H, Lécuyer M, et al. Myeloid cell transmigration across the CNS vasculature triggers IL-1β-driven neuroinflammation during autoimmune encephalomyelitis in mice. J Exp Med. 2016;213:929-49 pubmed publisher |
| Lin Q, Li C, Zha Q, Xu L, Pan H, Zhao G, et al. Gossypol induces pyroptosis in mouse macrophages via a non-canonical inflammasome pathway. Toxicol Appl Pharmacol. 2016;292:56-64 pubmed publisher |
| De Bruycker S, Vangestel C, Van den Wyngaert T, Wyffels L, Wouters A, Pauwels P, et al. Baseline [(18)F]FMISO μPET as a Predictive Biomarker for Response to HIF-1α Inhibition Combined with 5-FU Chemotherapy in a Human Colorectal Cancer Xenograft Model. Mol Imaging Biol. 2016;18:606-16 pubmed publisher |
| Fernandez M, Miller E, Krammer F, Gopal R, Greenbaum B, Bhardwaj N. Ion efflux and influenza infection trigger NLRP3 inflammasome signaling in human dendritic cells. J Leukoc Biol. 2016;99:723-34 pubmed publisher |
| Melehani J, James D, Dumont A, Torres V, Duncan J. Staphylococcus aureus Leukocidin A/B (LukAB) Kills Human Monocytes via Host NLRP3 and ASC when Extracellular, but Not Intracellular. PLoS Pathog. 2015;11:e1004970 pubmed publisher |
| Queen J, Agarwal S, Dolores J, Stehlik C, Satchell K. Mechanisms of inflammasome activation by Vibrio cholerae secreted toxins vary with strain biotype. Infect Immun. 2015;83:2496-506 pubmed publisher |
| Rimessi A, Bezzerri V, Patergnani S, Marchi S, Cabrini G, Pinton P. Mitochondrial Ca2+-dependent NLRP3 activation exacerbates the Pseudomonas aeruginosa-driven inflammatory response in cystic fibrosis. Nat Commun. 2015;6:6201 pubmed publisher |
| de Rivero Vaccari J, Brand F, Adamczak S, Lee S, Perez Barcena J, Wang M, et al. Exosome-mediated inflammasome signaling after central nervous system injury. J Neurochem. 2016;136 Suppl 1:39-48 pubmed publisher |
| Paciello I, Silipo A, Lembo Fazio L, Curcurù L, Zumsteg A, Noël G, et al. Intracellular Shigella remodels its LPS to dampen the innate immune recognition and evade inflammasome activation. Proc Natl Acad Sci U S A. 2013;110:E4345-54 pubmed publisher |
| Zhang X, Ibrahim E, de Rivero Vaccari J, Lotocki G, Aballa T, Dietrich W, et al. Involvement of the inflammasome in abnormal semen quality of men with spinal cord injury. Fertil Steril. 2013;99:118-24 pubmed publisher |
| Taxman D, Swanson K, Broglie P, Wen H, Holley Guthrie E, Huang M, et al. Porphyromonas gingivalis mediates inflammasome repression in polymicrobial cultures through a novel mechanism involving reduced endocytosis. J Biol Chem. 2012;287:32791-9 pubmed |
| Tomura S, de Rivero Vaccari J, Keane R, Bramlett H, Dietrich W. Effects of therapeutic hypothermia on inflammasome signaling after traumatic brain injury. J Cereb Blood Flow Metab. 2012;32:1939-47 pubmed publisher |
| de Rivero Vaccari J, Sawaya M, Brand F, Nusbaum B, Bauman A, Bramlett H, et al. Caspase-1 level is higher in the scalp in androgenetic alopecia. Dermatol Surg. 2012;38:1033-9 pubmed publisher |
| de Rivero Vaccari J, Bastien D, Yurcisin G, Pineau I, Dietrich W, De Koninck Y, et al. P2X4 receptors influence inflammasome activation after spinal cord injury. J Neurosci. 2012;32:3058-66 pubmed publisher |
| Mawhinney L, de Rivero Vaccari J, Dale G, Keane R, Bramlett H. Heightened inflammasome activation is linked to age-related cognitive impairment in Fischer 344 rats. BMC Neurosci. 2011;12:123 pubmed publisher |
| Nadeau S, Filali M, Zhang J, Kerr B, Rivest S, Soulet D, et al. Functional recovery after peripheral nerve injury is dependent on the pro-inflammatory cytokines IL-1? and TNF: implications for neuropathic pain. J Neurosci. 2011;31:12533-42 pubmed publisher |
| Taxman D, Holley Guthrie E, Huang M, Moore C, Bergstralh D, Allen I, et al. The NLR adaptor ASC/PYCARD regulates DUSP10, mitogen-activated protein kinase (MAPK), and chemokine induction independent of the inflammasome. J Biol Chem. 2011;286:19605-16 pubmed publisher |
| Atay S, Gercel Taylor C, Taylor D. Human trophoblast-derived exosomal fibronectin induces pro-inflammatory IL-1? production by macrophages. Am J Reprod Immunol. 2011;66:259-69 pubmed publisher |
| Rawat R, Cohen T, Ampong B, Francia D, Henriques Pons A, Hoffman E, et al. Inflammasome up-regulation and activation in dysferlin-deficient skeletal muscle. Am J Pathol. 2010;176:2891-900 pubmed publisher |
| Banerjee M, Datta M, Majumder P, Mukhopadhyay D, Bhattacharyya N. Transcription regulation of caspase-1 by R393 of HIPPI and its molecular partner HIP-1. Nucleic Acids Res. 2010;38:878-92 pubmed publisher |
| Craven R, Gao X, Allen I, Gris D, Bubeck Wardenburg J, McElvania TeKippe E, et al. Staphylococcus aureus alpha-hemolysin activates the NLRP3-inflammasome in human and mouse monocytic cells. PLoS ONE. 2009;4:e7446 pubmed publisher |
| Duncan J, Gao X, Huang M, O Connor B, Thomas C, Willingham S, et al. Neisseria gonorrhoeae activates the proteinase cathepsin B to mediate the signaling activities of the NLRP3 and ASC-containing inflammasome. J Immunol. 2009;182:6460-9 pubmed publisher |
| Hurst J, Prinz N, Lorenz M, Bauer S, Chapman J, Lackner K, et al. TLR7 and TLR8 ligands and antiphospholipid antibodies show synergistic effects on the induction of IL-1beta and caspase-1 in monocytes and dendritic cells. Immunobiology. 2009;214:683-91 pubmed publisher |
| Dostert C, Petrilli V, van Bruggen R, Steele C, Mossman B, Tschopp J. Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica. Science. 2008;320:674-7 pubmed publisher |
| Dorfleutner A, Bryan N, Talbott S, Funya K, Rellick S, Reed J, et al. Cellular pyrin domain-only protein 2 is a candidate regulator of inflammasome activation. Infect Immun. 2007;75:1484-92 pubmed |
